CCNT1

General Information

Gene Name : CCNT1
Gene ID : ENSG00000129315.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CCNT1)

Not Available

Antibody Validation

View validation images for all CCNT1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CCNT1	ENSG00000129315.10	16.73	15.99	16.36	ENCSR000AEF
HepG2	CCNT1	ENSG00000129315.10	11.42	12.09	11.75	ENCSR985KAT
K562	CCNT1	ENSG00000129315.10	19.61	22.49	21.05	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CCNT1-BGKcLV26-K562	ENCSR035MKJ	CCNT1	K562	Released		ENCSR900GQL	CRISPR	KD% = 74.6,72.5

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CCNT1	ENCAB283VHI	A303-496A	1	Released, ENCODE4		BGKcLV26-65, Released, ENCODE4
CCNT1	ENCAB973MTR	A303-497A	1	Released, ENCODE4		BGKcLV26-65, Released, ENCODE4
CCNT1		81464S	1	Submitted, ENCORE2	BGHcLV45-9, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CCNT1	K562	CRISPR	ENCSR035MKJ	ENCSR900GQL	CCNT1-BGKcLV26-65,CCNT1-BGKcLV26-66	NT-BGKcLV26-1,NT-BGKcLV26-2	74.6,72.5	Released	ENCODE4
CCNT1	K562	CRISPR			BGKcLV44-91,BGKcLV44-92	BGKcLV44-1,BGKcLV44-2	79.5,85.5	NotSatisfied	ENCORE2
CCNT1	K562	CRISPR			BGKcLV44-93,BGKcLV44-94	BGKcLV44-1,BGKcLV44-2	83.9,85.3	NotSatisfied	ENCORE2
CCNT1	HepG2	CRISPR			BGHcLV27-47,BGHcLV27-48	BGHcLV27-1,BGHcLV27-2	1.0,0.0	NotSatisfied	ENCODE4
CCNT1	HepG2	CRISPR			CCNT1-BGHcLV45-9,CCNT1-BGHcLV45-10	NT-BGHcLV45-1,NT-BGHcLV45-2	83.7,84.2148	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CCNT1	Product_ID: A303-496A Lot_ID: 1 Source: Bethyl Labs Target Name: CCNT1-human
CCNT1	Product_ID: A303-497A Lot_ID: 1 Source: Bethyl Labs Target Name: CCNT1-human
CCNT1	Product_ID: 81464S Lot_ID: 1 Source: Cell Signaling Technology Target Name: CCNT1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CCNT1 is not avaliable on ENCORE database.

Proteins bound to RNA

CCNT1 RNA is bound by 24 proteins.

CanvasJS.com

eCLIP assay for CCNT1 is not avaliable on ENCORE database.

24 proteins are bound to CCNT1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	49086182	49086255	-	3'-UTR,intron-Distal	5.05834	21.21593	K562	GTF2F1
chr12	49086196	49086245	-	3'-UTR,intron-Distal	4.94205	14.46250	K562	DDX6
chr12	49085036	49085136	-	3'-UTR,intron-Distal	5.11175	12.87307	K562	EXOSC5
chr12	49093518	49093606	-	CDS,intron-Distal,intron-Proximal	4.98805	12.15723	HepG2	PRPF8
chr12	49086180	49086254	-	3'-UTR,intron-Distal	3.55198	11.83905	K562	FAM120A
chr12	49086053	49086140	-	3'-UTR,intron-Distal	3.58761	9.80275	K562	FAM120A
chr12	49086058	49086173	-	3'-UTR,intron-Distal	4.64948	9.34567	HepG2	FUBP3
chr12	49100276	49100329	-	intron-Distal	4.83149	8.24653	K562	KHSRP
chr12	49084147	49084196	-	3'-UTR,intron-Distal	4.11821	7.31419	K562	EXOSC5
chr12	49091927	49091975	-	CDS,intron-Distal,intron-Proximal	5.15443	7.19009	HepG2	U2AF2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 55 entries

eCLIP assay for CCNT1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CCNT1 is not available on ENCORE database.
65 RBPs can affect the levels of CCNT1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CCNT1 is not available on ENCORE database.

65 RBPs can affect the gene expression of CCNT1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CCNT1	ENSG00000129315.5	7295.94990	3268.22320	1.15850	31.71090	29.91990	K562	AQR
CCNT1	ENSG00000129315.5	532.16530	925.70960	-0.79870	14.85040	13.69190	HepG2	TRIM56
CCNT1	ENSG00000129315.5	1952.59160	1290.79010	0.59700	13.44860	12.57450	HepG2	SRSF1
CCNT1	ENSG00000129315.5	2767.03810	1833.58060	0.59360	10.86800	9.26630	K562	U2AF2
CCNT1	ENSG00000129315.5	2352.55010	1740.22400	0.43490	9.33810	8.56740	HepG2	SRFBP1
CCNT1	ENSG00000129315.5	618.38940	944.23780	-0.61060	9.49280	8.42160	HepG2	HNRNPU
CCNT1	ENSG00000129315.5	3084.65660	1775.67010	0.79660	10.54740	8.20380	K562	U2AF1
CCNT1	ENSG00000129315.5	1586.74660	2088.76470	-0.39660	6.61770	5.79480	K562	AGGF1
CCNT1	ENSG00000129315.5	1694.89720	2272.98020	-0.42340	6.71790	5.66940	K562	EIF2S2
CCNT1	ENSG00000129315.5	2116.20950	2703.45030	-0.35330	6.62730	5.56950	K562	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 74 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CCNT1 is not available on ENCORE database.

13 RBPs can affect the splicing of CCNT1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.37900	0.00000	0.00004	excluded	K562	PRPF8
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.43600	0.00000	0.00000	excluded	K562	XRCC6
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.47400	0.00000	0.00048	excluded	HepG2	HNRNPU
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091962	-0.32100	0.00000	0.00001	excluded	K562	PTBP1
A3SS	CCNT1	ENSG00000129315.5	chr12	-	49094795	49094884			49094795	49094856	49099550	49099742	0.32200	0.00000	0.00000	longer	K562	AQR
MXE	CCNT1	ENSG00000129315.5	chr12	-	49094795	49094856	49099550	49099679	49082246	49088219	49108225	49108307	-0.29200	0.00002	0.00087	2included	K562	PUS1
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.30600	0.00010	0.03033	excluded	K562	SERBP1
SE	CCNT1	ENSG00000129315.5	chr12	-	49099550	49099679			49082246	49088219	49108225	49108307	-0.40500	0.00014	0.00326	excluded	K562	PUS1
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.35500	0.00014	0.00638	excluded	HepG2	SF3A3
SE	CCNT1	ENSG00000129315.5	chr12	-	49089781	49089945			49089541	49089612	49091920	49091966	-0.25000	0.00024	0.00637	excluded	K562	SF3B4

Showing 1 to 10 of 19 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CCNT1

General Information

Functions

Localization

Domains (AlphaFold: CCNT1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CCNT1 is not avaliable on ENCORE database.

24 proteins are bound to CCNT1 RNA:

eCLIP assay for CCNT1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CCNT1 is not available on ENCORE database.

65 RBPs can affect the gene expression of CCNT1 :

The Knockdown/knockout RNA-Seq assay for CCNT1 is not available on ENCORE database.

13 RBPs can affect the splicing of CCNT1 :

The Knockdown/knockout RNA-Seq assay for CCNT1 is not avaliable on ENCORE database.