NGDN

General Information

Gene Name       : NGDN
Gene ID             : ENSG00000129460.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NGDN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NGDNENSG00000129460.1545.3642.4343.89ENCSR000AEF
HepG2NGDNENSG00000129460.15167.84184.43176.13ENCSR985KAT
K562NGDNENSG00000129460.1551.9549.8050.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NGDN is not avaliable on ENCORE database.



Proteins bound to RNA
  • NGDN RNA is bound by 28 proteins.  







eCLIP assay for NGDN is not avaliable on ENCORE database.





28 proteins are bound to NGDN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr142394725423947359+3'-UTR,intron-Distal4.2756511.93232HepG2LARP4
chr142394673423946810+3'-UTR,CDS,intron-Proximal4.8007711.09609HepG2PRPF8
chr142394724923947357+3'-UTR,intron-Distal3.627285.35418HepG2FUBP3
chr142394718923947257+3'-UTR,CDS,intron-Distal,intron-Proximal3.450389.30274HepG2U2AF2
chr142394640823946546+3'-UTR,CDS,intron-Proximal3.262224.70577HepG2G3BP1
chr142394726623947370+3'-UTR,intron-Distal3.443638.02252HepG2ZC3H11A
chr142394716423947219+3'-UTR,CDS,intron-Distal,intron-Proximal3.993204.69223K562SF3B4
chr142394675323946784+3'-UTR,CDS,intron-Proximal3.551575.74979HepG2GRWD1
chr142394640823946471+3'-UTR,CDS,intron-Proximal4.423803.66349K562LIN28B
chr142394724323947337+3'-UTR,intron-Distal5.4354862.22407K562PUM2
chr142394666223946807+3'-UTR,CDS,intron-Proximal4.1423815.79499HepG2BUD13
chr142394670523946777+3'-UTR,CDS,intron-Proximal3.548043.66187K562ZNF622
chr142393921223939343+5'-UTR,CDS,intron-Proximal3.173479.47473HepG2EFTUD2
chr142393891723938979+5'-UTR,CDS,intron-Proximal3.704035.76569HepG2PRPF8
chr142393927723939311+5'-UTR,CDS,intron-Proximal3.092326.90893HepG2GRWD1
chr142393922023939291+5'-UTR,CDS,intron-Proximal3.856035.73990HepG2PRPF8
chr142393891123938938+5'-UTR,CDS,intron-Proximal3.556677.16836HepG2NCBP2
chr142393896123939086+5'-UTR,intron-Distal,intron-Proximal3.848729.63838HepG2EFTUD2
chr142393923023939334+5'-UTR,CDS,intron-Proximal3.4999214.39942HepG2BUD13
chr142394544623945542+5'-UTR,CDS,intron-Proximal3.4469113.12156HepG2BCLAF1
chr142393924023939299+5'-UTR,CDS,intron-Proximal5.069607.45424HepG2AQR
chr142393929923939311+5'-UTR,CDS,intron-Proximal4.263673.28019K562DDX3X
chr142394544923945522+5'-UTR,CDS3.635434.31813HepG2G3BP1
chr142393925023939291+5'-UTR,CDS,intron-Proximal4.762606.89039K562RBM15
chr142394547123945524+5'-UTR,CDS3.399379.91328HepG2PPIG
chr142393891823938938+5'-UTR,CDS,intron-Proximal4.362915.16052K562RBM15
chr142394552023945575+5'-UTR,CDS3.272548.35247HepG2GRWD1
chr142394558423945616+5'-UTR,CDS4.062993.47885K562LIN28B
chr142393893123939009+5'-UTR,CDS,intron-Proximal5.082406.04760K562AQR
chr142394544323945520+5'-UTR,CDS,intron-Proximal3.257494.67625HepG2ZNF800
chr142394544623945471+5'-UTR,CDS,intron-Proximal3.748919.97127HepG2PPIG
chr142393925523939308+5'-UTR,CDS3.909843.04254K562UCHL5
chr142394545323945527+5'-UTR,CDS3.496854.40383K562UCHL5
chr142394544523945469+5'-UTR,CDS,intron-Proximal3.328537.88565HepG2GRWD1
chr142394545223945521+5'-UTR,CDS3.616243.29519HepG2UCHL5
chr142394011323940186+5'-UTR,CDS,intron-Proximal3.006526.92518HepG2PPIG
chr142394443123944494+CDS3.8751810.84088HepG2GRWD1
chr142394528123945362+CDS,intron-Proximal4.4031012.70642HepG2GRWD1
chr142394438023944409+CDS4.450155.47493HepG2BUD13
chr142394526123945267+CDS4.8623713.19760K562LIN28B
chr142394438323944431+CDS3.424347.44851HepG2GRWD1
chr142394655123946567+CDS,intron-Proximal3.813148.76261HepG2GRWD1
chr142394526723945294+CDS4.350838.58756K562LIN28B
chr142394532623945358+CDS3.409235.21025HepG2PPIG
chr142394474923944837+CDS,intron-Distal,intron-Proximal3.417247.38298HepG2AQR
chr142394443623944525+CDS,intron-Proximal3.542043.10693HepG2UCHL5
chr142394651723946571+CDS,intron-Proximal3.442173.90826K562ZNF622
chr142394496123944988+CDS,intron-Distal,intron-Proximal4.691096.59937HepG2LIN28B
chr142394523823945309+CDS4.704195.71225HepG2G3BP1
chr142394517223945285+CDS,intron-Proximal3.420753.37120HepG2SF3B4
chr142394497323944987+CDS,intron-Distal5.2974217.75173K562LIN28B
chr142394018323940229+CDS,intron-Proximal4.630254.35676HepG2PRPF8
chr142394671023946728+CDS,intron-Proximal3.297786.83963HepG2GRWD1
chr142394651923946576+CDS,intron-Proximal3.332067.51172HepG2PPIG
chr142394650823946551+CDS5.4440311.76439HepG2GRWD1
chr142394523623945261+CDS,intron-Proximal5.9163430.20920K562LIN28B
chr142394523623945266+CDS,intron-Proximal4.9266118.23578HepG2LIN28B
chr142394642723946493+CDS3.128956.21281HepG2GRWD1
chr142394477323944805+CDS,intron-Distal3.148555.76243HepG2BUD13
chr142394531923945361+CDS3.226437.49108HepG2BCLAF1
chr142394526623945309+CDS3.827274.63409HepG2LIN28B
chr142394531823945362+CDS,intron-Proximal4.113903.68241HepG2G3BP1
chr142394503023945085+intron-Distal,intron-Proximal4.553613.77802HepG2U2AF2
chr142395604123956217+intron-Distal3.8098910.77637HepG2PTBP1
chr142395285923952955+intron-Distal3.039493.17725HepG2PTBP1
chr142395581223955950+intron-Distal3.6678815.23340HepG2SUGP2
chr142396883123969024+intron-Distal3.599155.50064HepG2PTBP1
chr142395661923956680+intron-Distal4.2655311.27213HepG2RBFOX2
chr142395473623954763+intron-Distal3.091593.46325HepG2SUGP2
chr142395392223953966+intron-Distal4.300213.62238HepG2MATR3
chr142395606223956202+intron-Distal4.076488.02679HepG2MATR3
chr142395376223953818+intron-Distal3.457216.72722HepG2SUGP2
chr142395526423955285+intron-Distal3.174443.34056HepG2MATR3
chr142395353223953563+intron-Distal4.196983.96879HepG2MATR3
chr142395268823952755+intron-Distal3.316033.60809HepG2HNRNPK
chr142395386823953922+intron-Distal3.825706.02668HepG2SUGP2
chr142396883223969013+intron-Distal4.477347.67287HepG2MATR3
chr142395547923955537+intron-Distal4.933736.08205HepG2MATR3
chr142395580823955904+intron-Distal4.5830111.03373HepG2MATR3
chr142395287323952907+intron-Distal3.678723.10961HepG2MATR3
chr142395663523956671+intron-Distal3.696244.57452HepG2SUGP2
chr142395659023956619+intron-Distal5.001226.92529HepG2RBFOX2
chr142395176923951866+intron-Distal4.101443.63122HepG2PRPF4
chr142395216223952228+intron-Distal4.230197.24590HepG2MATR3
chr142395536123955387+intron-Distal3.444223.91859HepG2SUGP2
chr142395394523953991+intron-Distal4.728787.09509HepG2SUGP2
chr142395301323953087+intron-Distal3.529836.21102HepG2MATR3
chr142395557923955698+intron-Distal3.5661710.18635HepG2SUGP2
chr142395548823955546+intron-Distal3.8348010.05116HepG2SUGP2
chr142396898723969112+intron-Distal3.273353.00129HepG2SUGP2
chr142394513023945191+intron-Distal,intron-Proximal4.3213811.45682HepG2U2AF2
chr142394376423943874+intron-Distal3.390336.90182HepG2HNRNPL
chr142395646923956530+intron-Distal3.925694.61322HepG2MATR3
chr142394663523946687+intron-Proximal3.578794.50387HepG2AQR
chr142394634923946405+intron-Proximal4.455944.32536HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NGDN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NGDN is not available on ENCORE database.

  • 74 RBPs can affect the levels of NGDN.  








The Knockdown/knockout RNA-Seq assay for NGDN is not available on ENCORE database.





74 RBPs can affect the gene expression of NGDN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NGDNENSG00000129460.113109.245802314.630500.425703.260602.68990HepG2AKAP1
NGDNENSG00000129460.11951.391901273.24950-0.420402.733601.83950HepG2BCLAF1
NGDNENSG00000129460.111658.694901358.427700.288004.122503.34160HepG2CKAP4
NGDNENSG00000129460.111485.857801256.611400.241702.884802.03470HepG2DDX19B
NGDNENSG00000129460.111109.977101831.11980-0.722207.681706.72990HepG2EIF2S1
NGDNENSG00000129460.111469.407001970.11070-0.423002.462301.81140HepG2EIF4B
NGDNENSG00000129460.112656.014102310.467900.201002.489201.68670HepG2EIF4G1
NGDNENSG00000129460.111652.581802213.23300-0.421403.862902.91150HepG2EIF4G2
NGDNENSG00000129460.111781.855401327.712700.424304.020403.01480HepG2EWSR1
NGDNENSG00000129460.111844.729602152.21210-0.222402.166901.33000HepG2HNRNPA2B1
NGDNENSG00000129460.111646.107201958.57500-0.250702.716902.00570HepG2HNRNPF
NGDNENSG00000129460.111811.217002132.99160-0.235903.099002.38880HepG2HNRNPL
NGDNENSG00000129460.111043.697201581.30430-0.599406.297405.39120HepG2HNRNPLL
NGDNENSG00000129460.111535.606201928.64690-0.328803.180802.40890HepG2IGF2BP1
NGDNENSG00000129460.111427.764601936.31150-0.439602.731401.73590HepG2KHSRP
NGDNENSG00000129460.111195.716501612.76490-0.431702.339501.45470HepG2MTPAP
NGDNENSG00000129460.111684.926902102.06370-0.319101.876601.34860HepG2NCBP2
NGDNENSG00000129460.111124.481401402.14200-0.318402.223401.55010HepG2NSUN2
NGDNENSG00000129460.111183.160401872.32050-0.662206.026904.97230HepG2PABPC4
NGDNENSG00000129460.111628.949301981.15480-0.282403.462302.86510HepG2PTBP1
NGDNENSG00000129460.111689.959002216.65070-0.391403.905103.21020HepG2PUF60
NGDNENSG00000129460.111944.958202351.39140-0.273802.477901.84320HepG2PUM2
NGDNENSG00000129460.111576.059702145.55400-0.445006.339705.44900HepG2QKI
NGDNENSG00000129460.112277.097401830.114200.315203.351602.41610HepG2RBM15
NGDNENSG00000129460.113051.919402303.748900.405606.792906.06640HepG2RBM22
NGDNENSG00000129460.111463.662501947.26050-0.411904.522903.67770HepG2RBM25
NGDNENSG00000129460.111635.783802204.80170-0.430707.424506.61380HepG2NELFE
NGDNENSG00000129460.111684.229002053.53370-0.286003.661102.96520HepG2RECQL
NGDNENSG00000129460.113571.711001565.904901.189509.745808.41930HepG2SF3A3
NGDNENSG00000129460.111698.505202062.56590-0.280203.511002.85580HepG2SF3B4
NGDNENSG00000129460.111725.941802125.62660-0.300503.831003.02620HepG2SLBP
NGDNENSG00000129460.113782.575802601.974400.5397016.4728015.51900HepG2SRFBP1
NGDNENSG00000129460.113000.459902152.901600.4788011.5227010.69990HepG2SRSF1
NGDNENSG00000129460.111423.846701751.52550-0.298804.077703.43230HepG2SRSF9
NGDNENSG00000129460.112199.169702489.09700-0.178701.893401.36110HepG2SUCLG1
NGDNENSG00000129460.111406.051301935.19350-0.460807.171106.34140HepG2TAF15
NGDNENSG00000129460.11982.639101541.33060-0.649407.879506.73810HepG2TARDBP
NGDNENSG00000129460.111489.894401778.09260-0.255102.067201.34180HepG2TIA1
NGDNENSG00000129460.111020.887201273.69740-0.319203.787303.14980HepG2TRIM56
NGDNENSG00000129460.111777.089202165.73620-0.285302.355601.55580HepG2TUFM
NGDNENSG00000129460.112144.826701460.705200.554106.650705.68990HepG2U2AF1
NGDNENSG00000129460.111068.94790847.235200.335302.214401.53520HepG2UCHL5
NGDNENSG00000129460.111209.125401388.71860-0.199801.913601.31490HepG2UPF1
NGDNENSG00000129460.112418.529301340.752700.8510029.5187027.87780HepG2UTP3
NGDNENSG00000129460.112027.489801527.324100.408608.863408.02710HepG2ZNF622
NGDNENSG00000129460.11746.01550459.897200.697809.202008.24370K562AGGF1
NGDNENSG00000129460.11709.21900478.535700.567504.770703.90580K562AKAP8L
NGDNENSG00000129460.112009.240001011.990400.9894017.7846016.46410K562AQR
NGDNENSG00000129460.11639.05240502.083600.347902.450901.59500K562ATP5C1
NGDNENSG00000129460.11519.84570657.20360-0.338302.689901.74210K562BCLAF1
NGDNENSG00000129460.111151.10560807.362300.511606.677405.72910K562DDX47
NGDNENSG00000129460.11670.51350514.990200.380603.043702.11830K562DKC1
NGDNENSG00000129460.11711.64850498.013700.514903.846502.75730K562EFTUD2
NGDNENSG00000129460.11620.89050850.67100-0.454304.785803.87340K562EIF2S2
NGDNENSG00000129460.11624.13160480.898600.376002.322201.59020K562EIF3G
NGDNENSG00000129460.11476.32400355.564600.421702.487001.70890K562EIF4A3
NGDNENSG00000129460.11704.34750369.770400.9296014.0945012.83320K562FXR1
NGDNENSG00000129460.11353.97950511.23580-0.530303.672002.99700K562HNRNPC
NGDNENSG00000129460.11802.89030486.596100.722406.711304.72260K562HNRNPK
NGDNENSG00000129460.111050.12780658.856000.672406.185504.71770K562HNRNPM
NGDNENSG00000129460.11770.53180507.874800.601305.446604.20340K562KIF1C
NGDNENSG00000129460.11730.14030512.030400.511804.665303.56750K562MAGOH
NGDNENSG00000129460.11779.36780568.944000.453903.419502.39070K562MBNL1
NGDNENSG00000129460.11765.93430398.786000.941503.666302.61720K562NAA15
NGDNENSG00000129460.11789.37880455.579600.792908.933707.14700K562PCBP2
NGDNENSG00000129460.11508.33960665.21400-0.388002.167701.43130K562PCBP3
NGDNENSG00000129460.111339.18380484.624201.4663029.2162026.78770K562PRPF8
NGDNENSG00000129460.11738.56880497.469800.570005.818104.88410K562PTBP1
NGDNENSG00000129460.111746.713301285.621300.442104.106603.11910K562PUF60
NGDNENSG00000129460.111303.60530474.634901.4575028.4772026.71920K562PUS1
NGDNENSG00000129460.11776.58290462.411500.747904.159103.44880K562RBM15
NGDNENSG00000129460.11752.13680477.012200.656906.582705.21600K562RBM22
NGDNENSG00000129460.11305.31850418.20830-0.453902.591301.63610K562RCC2
NGDNENSG00000129460.11647.53320493.659100.391302.090801.38520K562RPS19
NGDNENSG00000129460.11646.22350423.112200.610906.425005.08340K562SF3B4
NGDNENSG00000129460.11878.43480487.686700.8489011.8580010.40020K562SRSF1
NGDNENSG00000129460.11750.76190511.781400.552705.507304.34050K562SYNCRIP
NGDNENSG00000129460.11354.42310468.37870-0.402202.269201.42540K562TRIM56
NGDNENSG00000129460.11653.38570394.450600.728005.949704.21000K562U2AF1
NGDNENSG00000129460.11631.50420407.333800.632506.526805.29970K562U2AF2
NGDNENSG00000129460.11811.56360481.170900.754103.631402.08880K562UTP18
NGDNENSG00000129460.11460.45940618.09420-0.424803.163702.23120K562WDR3
NGDNENSG00000129460.11927.660501140.12590-0.297502.170701.41710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NGDN is not available on ENCORE database.





12 RBPs can affect the splicing of NGDN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENGDNENSG00000129460.11chr14+2395640523956465239467112394676923978548239790710.287000.001010.06051includedHepG2SRSF9
A5SSNGDNENSG00000129460.11chr14+2393921423939431239392142393931023940114239403890.071000.000000.00007longerK562AQR
RINGDNENSG00000129460.11chr14+2394437923944851239443792394451723944766239448510.152000.000000.00000includedK562PUS1
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.491000.000000.00000includedK562PUS1
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.051000.000210.00405includedHepG2PRPF8
RINGDNENSG00000129460.11chr14+239464082394676923946408239465652394671123946769-0.054000.002550.05015excludedK562SRSF1
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.303000.000000.00000includedK562AGGF1
RINGDNENSG00000129460.11chr14+2394437923944851239443792394451723944766239448510.060000.000080.00126includedK562AKAP8L
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.269000.000000.00000includedK562AKAP8L
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.122000.000010.00181includedK562WDR3
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.273000.000000.00000includedK562RBM15
RINGDNENSG00000129460.11chr14+239443792394536123944379239445172394523723945361-0.540000.007640.04962excludedHepG2SF3B4
RINGDNENSG00000129460.11chr14+2394437923944851239443792394451723944766239448510.075000.000050.00108includedK562UTP18
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.311000.000000.00000includedK562UTP18
RINGDNENSG00000129460.11chr14+2394437923944851239443792394451723944766239448510.055000.000000.00000includedK562AQR
RINGDNENSG00000129460.11chr14+2394640823946769239464082394656523946711239467690.285000.000000.00000includedK562AQR
RINGDNENSG00000129460.11chr14+239464082394676923946408239465652394671123946769-0.111000.000050.00173excludedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NGDN is not avaliable on ENCORE database.