SRPRB

General Information

Gene Name : SRPRB
Gene ID : ENSG00000144867.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SRPRB)

Not Available

Antibody Validation

Bethyl Labs: A305-440A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SRPRB	ENSG00000144867.11	26.75	31.51	29.13	ENCSR000AEF
HepG2	SRPRB	ENSG00000144867.11	36.27	48.54	42.41	ENCSR985KAT
K562	SRPRB	ENSG00000144867.11	31.67	34.34	33.01	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SRPRB		A305-440A	1				BGHcLV36-41, Submitted, ENCORE2	BGKcLV37-43, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
SRPRB	K562	CRISPR			SRPRB-BGKcLV37-43,SRPRB-BGKcLV37-44	NT-BGKcLV37-1,NT-BGKcLV37-2	61.8,65.2	Submitting	ENCORE2
SRPRB	HepG2	CRISPR			SRPRB-BGHcLV36-41,SRPRB-BGHcLV36-42	NT-BGHcLV36-1,NT-BGHcLV36-2	74.7,64.9	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SRPRB	Product_ID: A305-440A Lot_ID: 1 Source: Bethyl Labs Target Name: SRPRB-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SRPRB is not avaliable on ENCORE database.

Proteins bound to RNA

SRPRB RNA is bound by 12 proteins.

CanvasJS.com

eCLIP assay for SRPRB is not avaliable on ENCORE database.

12 proteins are bound to SRPRB RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	133524665	133524794	+	3'-UTR,5'-UTR,CDS	5.61042	21.71690	HepG2	DDX3X
chr3	133538400	133538494	+	CDS	4.35558	16.94123	HepG2	SND1
chr3	133524668	133524824	+	3'-UTR,5'-UTR,CDS	4.14102	11.42614	K562	DDX3X
chr3	133524696	133524823	+	CDS	4.54414	10.82619	HepG2	RPS3
chr3	133539299	133539393	+	3'-UTR,intron-Distal	5.74074	10.75082	HepG2	UPF1
chr3	133538499	133538623	+	3'-UTR,CDS	4.12910	10.11508	HepG2	RPS3
chr3	133538514	133538587	+	CDS	4.28518	9.64451	HepG2	SND1
chr3	133539330	133539410	+	3'-UTR,intron-Distal	5.47791	8.76530	K562	UPF1
chr3	133539085	133539159	+	3'-UTR,intron-Distal	4.96254	6.96152	HepG2	UPF1
chr3	133529960	133530011	+	CDS,intron-Proximal	4.92773	6.43734	HepG2	SND1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 34 entries

eCLIP assay for SRPRB is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SRPRB is not available on ENCORE database.
100 RBPs can affect the levels of SRPRB.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SRPRB is not available on ENCORE database.

100 RBPs can affect the gene expression of SRPRB :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SRPRB	ENSG00000144867.7	1652.74070	775.67430	1.09120	36.60540	34.79350	HepG2	UTP3
SRPRB	ENSG00000144867.7	2513.59460	1086.74080	1.20960	22.74510	21.13010	HepG2	DDX3X
SRPRB	ENSG00000144867.7	2633.92690	1134.46390	1.21510	19.88860	18.59780	HepG2	AKAP1
SRPRB	ENSG00000144867.7	2282.88190	1006.58220	1.18130	19.25210	17.70670	HepG2	MATR3
SRPRB	ENSG00000144867.7	1340.01020	883.61210	0.60070	13.49100	12.51090	HepG2	ZNF622
SRPRB	ENSG00000144867.7	1636.24460	996.33150	0.71560	12.78760	11.60240	HepG2	CELF1
SRPRB	ENSG00000144867.7	1463.32230	670.38430	1.12610	13.03140	11.23420	K562	RPS19
SRPRB	ENSG00000144867.7	884.61620	544.60210	0.69970	12.11690	10.91610	HepG2	SAFB2
SRPRB	ENSG00000144867.7	1196.34690	795.67990	0.58830	11.54070	10.37060	HepG2	CKAP4
SRPRB	ENSG00000144867.7	946.25760	540.50010	0.80780	12.06130	10.34530	K562	SYNCRIP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 112 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SRPRB is not available on ENCORE database.

5 RBPs can affect the splicing of SRPRB :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	SRPRB	ENSG00000144867.7	chr3	+	133535702	133535776	133535721	133535776	133534433	133534570	0.08800	0.00000	0.00000	longer	K562	AQR
SE	SRPRB	ENSG00000144867.7	chr3	+	133529960	133530043	133526589	133526667	133534433	133534570	-0.14900	0.00006	0.00205	excluded	K562	U2AF1
SE	SRPRB	ENSG00000144867.7	chr3	+	133529960	133530043	133526589	133526667	133534433	133534570	-0.06900	0.00067	0.02019	excluded	K562	AGGF1
SE	SRPRB	ENSG00000144867.7	chr3	+	133529960	133530043	133526589	133526667	133534433	133534570	-0.05800	0.00174	0.04151	excluded	K562	RBM15
SE	SRPRB	ENSG00000144867.7	chr3	+	133529960	133530043	133526589	133526667	133534433	133534570	-0.05100	0.00412	0.05375	excluded	K562	PUS1

Showing 1 to 5 of 5 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SRPRB

General Information

Functions

Localization

Domains (AlphaFold: SRPRB)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SRPRB is not avaliable on ENCORE database.

12 proteins are bound to SRPRB RNA:

eCLIP assay for SRPRB is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SRPRB is not available on ENCORE database.

100 RBPs can affect the gene expression of SRPRB :

The Knockdown/knockout RNA-Seq assay for SRPRB is not available on ENCORE database.

5 RBPs can affect the splicing of SRPRB :

The Knockdown/knockout RNA-Seq assay for SRPRB is not avaliable on ENCORE database.