CLASP2

General Information

Gene Name : CLASP2
Gene ID : ENSG00000163539.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CLASP2)

Not Available

Antibody Validation

Bethyl Labs: A302-155A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CLASP2	ENSG00000163539.16	16.78	17.66	17.22	ENCSR000AEF
HepG2	CLASP2	ENSG00000163539.16	13.74	17.11	15.43	ENCSR985KAT
K562	CLASP2	ENSG00000163539.16	37.80	45.27	41.53	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CLASP2-BGKcLV28-K562	ENCSR331MLG	CLASP2	K562	Released		ENCSR220DTX	CRISPR	KD% = 57.9,55.0

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CLASP2	ENCAB751CST	A302-155A	2			Released, ENCODE4		BGKcLV28-19, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CLASP2	K562	CRISPR	ENCSR331MLG	ENCSR220DTX	CLASP2-BGKcLV28-19,CLASP2-BGKcLV28-20	NT-BGKcLV28-1,NT-BGKcLV28-2	57.9,55.0	Released	ENCODE4
CLASP2	HepG2	CRISPR			BGHcLV29-19,BGHcLV29-20	BGHcLV29-1,BGHcLV29-2	no clear band,	NotSatisfied	ENCODE4
CLASP2	HepG2	CRISPR			BGHcLV34-9,BGHcLV34-10	BGHcLV34-1,BGHcLV34-2	no clear band,	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CLASP2	Product_ID: A302-155A Lot_ID: 2 Source: Bethyl Labs Target Name: CLASP2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CLASP2 is not avaliable on ENCORE database.

Proteins bound to RNA

CLASP2 RNA is bound by 39 proteins.

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eCLIP assay for CLASP2 is not avaliable on ENCORE database.

39 proteins are bound to CLASP2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	33702886	33703026	-	intron-Distal	5.87309	24.33261	K562	QKI
chr3	33692005	33692082	-	intron-Distal	5.25432	22.57437	K562	PTBP1
chr3	33692174	33692292	-	intron-Distal	4.32336	21.06121	K562	PTBP1
chr3	33539751	33539796	-	3'-UTR,intron-Distal	4.53612	19.01326	K562	PUM2
chr3	33686306	33686396	-	5'-UTR,CDS,intron-Distal,intron-Proximal	6.26662	17.69106	HepG2	BCLAF1
chr3	33692019	33692171	-	intron-Distal	5.92918	16.12824	K562	MATR3
chr3	33692103	33692174	-	intron-Distal	5.34813	14.02358	K562	PTBP1
chr3	33611535	33611655	-	intron-Distal	4.11582	12.39197	K562	KHSRP
chr3	33704511	33704575	-	intron-Distal	5.73359	11.38968	K562	KHSRP
chr3	33759457	33759672	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.59123	11.10825	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 166 entries

eCLIP assay for CLASP2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CLASP2 is not available on ENCORE database.
109 RBPs can affect the levels of CLASP2.

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The Knockdown/knockout RNA-Seq assay for CLASP2 is not available on ENCORE database.

109 RBPs can affect the gene expression of CLASP2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CLASP2	ENSG00000163539.11	1818.50600	764.93390	1.24920	46.52860	45.10350	HepG2	SRSF1
CLASP2	ENSG00000163539.11	1404.53820	2717.21910	-0.95200	30.93720	28.57160	K562	SF3A3
CLASP2	ENSG00000163539.11	322.08430	733.59040	-1.18750	25.44060	23.75830	HepG2	SAFB2
CLASP2	ENSG00000163539.11	2229.73510	3666.71070	-0.71760	13.89120	12.17720	K562	GRSF1
CLASP2	ENSG00000163539.11	437.90430	800.41740	-0.87010	13.00890	12.06150	HepG2	TIAL1
CLASP2	ENSG00000163539.11	1162.14640	687.53760	0.75720	13.09530	12.01120	HepG2	TAF15
CLASP2	ENSG00000163539.11	1469.33060	2340.28990	-0.67150	12.75840	10.83350	K562	SF3B4
CLASP2	ENSG00000163539.11	725.13170	1108.19960	-0.61190	12.03290	10.71810	HepG2	HNRNPL
CLASP2	ENSG00000163539.11	502.69600	823.75830	-0.71250	11.49990	10.33450	HepG2	HNRNPU
CLASP2	ENSG00000163539.11	875.99590	1382.31360	-0.65810	11.08080	10.19490	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 130 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CLASP2 is not available on ENCORE database.

13 RBPs can affect the splicing of CLASP2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CLASP2	ENSG00000163539.11	chr3	-	33605455	33605458			33602299	33602463	33612218	33612282	-0.50000	0.00001	0.00193	excluded	HepG2	QKI
SE	CLASP2	ENSG00000163539.11	chr3	-	33605455	33605458			33602299	33602463	33612218	33612282	-0.29200	0.00001	0.00252	excluded	K562	HNRNPM
A3SS	CLASP2	ENSG00000163539.11	chr3	-	33580280	33580491			33580280	33580434	33584924	33585031	0.05400	0.00003	0.00031	longer	K562	AQR
SE	CLASP2	ENSG00000163539.11	chr3	-	33653492	33653563			33650058	33650118	33661094	33661230	-0.10200	0.00017	0.00524	excluded	K562	U2AF1
MXE	CLASP2	ENSG00000163539.11	chr3	-	33543143	33543260	33552049	33552256	33537736	33540209	33557514	33557643	0.16400	0.00017	0.03316	1included	K562	SMNDC1
A3SS	CLASP2	ENSG00000163539.11	chr3	-	33653492	33653596			33653492	33653563	33661094	33661230	0.05400	0.00018	0.00145	longer	K562	AQR
SE	CLASP2	ENSG00000163539.11	chr3	-	33586766	33586839			33586189	33586333	33592743	33592887	0.05200	0.00023	0.00620	included	K562	SRSF1
SE	CLASP2	ENSG00000163539.11	chr3	-	33586766	33586839			33586189	33586333	33592743	33592887	0.08400	0.00036	0.03661	included	K562	XRCC6
SE	CLASP2	ENSG00000163539.11	chr3	-	33636442	33636460			33633886	33633988	33644443	33644617	-0.11300	0.00064	0.04651	excluded	K562	HNRNPL
SE	CLASP2	ENSG00000163539.11	chr3	-	33681360	33681564			33673783	33673863	33686248	33686395	0.18500	0.00118	0.02570	included	K562	U2AF1

Showing 1 to 10 of 16 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CLASP2

General Information

Functions

Localization

Domains (AlphaFold: CLASP2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CLASP2 is not avaliable on ENCORE database.

39 proteins are bound to CLASP2 RNA:

eCLIP assay for CLASP2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CLASP2 is not available on ENCORE database.

109 RBPs can affect the gene expression of CLASP2 :

The Knockdown/knockout RNA-Seq assay for CLASP2 is not available on ENCORE database.

13 RBPs can affect the splicing of CLASP2 :

The Knockdown/knockout RNA-Seq assay for CLASP2 is not avaliable on ENCORE database.