ALDOA

General Information

Gene Name : ALDOA
Gene ID : ENSG00000149925.18
Essential Gene : Yes

Functions

Novel RBP

Localization

Not Available

Domains (AlphaFold: ALDOA)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

Bethyl Labs: A304-495A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ALDOA	ENSG00000149925.18	189.50	511.24	350.37	ENCSR000AEF
HepG2	ALDOA	ENSG00000149925.18	1790.14	845.13	1317.63	ENCSR985KAT
K562	ALDOA	ENSG00000149925.18	1452.12	990.04	1221.08	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	ALDOA-BGKcLV26-K562	ENCSR071DBC	ALDOA	K562	Released		ENCSR900GQL	CRISPR	KD% = 70.0,72.0
knockdown followed by RNA-seq	ALDOA-BGHcLV27-HepG2	ENCSR735FXX	ALDOA	HepG2	Released		ENCSR650TTU	CRISPR	KD% = 87.9,87.2

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
ALDOA	ENCAB040UCI	A304-495A	1				BGHcLV27-7, Released, ENCODE4	BGKcLV26-23, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
ALDOA	K562	CRISPR	ENCSR071DBC	ENCSR900GQL	ALDOA-BGKcLV26-23,ALDOA-BGKcLV26-24	NT-BGKcLV26-1,NT-BGKcLV26-2	70.0,72.0	Released	ENCODE4
ALDOA	HepG2	CRISPR	ENCSR735FXX	ENCSR650TTU	ALDOA-BGHcLV27-7,ALDOA-BGHcLV27-8	NT-BGHcLV27-1,NT-BGHcLV27-2	87.9,87.2	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
ALDOA	Product_ID: A304-495A Lot_ID: 1 Source: Bethyl Labs Target Name: ALDOA-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ALDOA is not avaliable on ENCORE database.

Proteins bound to RNA

ALDOA RNA is bound by 39 proteins.

CanvasJS.com

eCLIP assay for ALDOA is not avaliable on ENCORE database.

39 proteins are bound to ALDOA RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	30081594	30081609	+	3'-UTR,intron-Proximal	3.37568	400.00000	K562	XRCC6
chr16	30081536	30081577	+	3'-UTR,intron-Proximal	4.23974	400.00000	K562	METAP2
chr16	30081635	30081680	+	3'-UTR	3.81314	400.00000	K562	METAP2
chr16	30081677	30081689	+	3'-UTR	6.41226	400.00000	HepG2	SUB1
chr16	30081660	30081677	+	3'-UTR	5.06443	400.00000	K562	PABPC4
chr16	30081567	30081572	+	3'-UTR,intron-Proximal	3.02011	400.00000	K562	YBX3
chr16	30081509	30081524	+	3'-UTR,CDS	3.54380	400.00000	K562	PABPC4
chr16	30081548	30081557	+	3'-UTR,intron-Proximal	3.04107	400.00000	K562	YBX3
chr16	30081526	30081583	+	3'-UTR,CDS,intron-Proximal	3.14365	400.00000	HepG2	LARP4
chr16	30081597	30081677	+	3'-UTR,intron-Proximal	3.29755	400.00000	HepG2	SUB1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 387 entries

eCLIP assay for ALDOA is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ALDOA is not available on ENCORE database.
137 RBPs can affect the levels of ALDOA.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ALDOA is not available on ENCORE database.

137 RBPs can affect the gene expression of ALDOA :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ALDOA	ENSG00000149925.12	10045.88580	58181.73220	-2.53400	134.28610	132.26320	HepG2	SRSF1
ALDOA	ENSG00000149925.12	9307.25400	23940.07270	-1.36300	71.64390	69.74610	HepG2	TIAL1
ALDOA	ENSG00000149925.12	13266.00130	43778.45750	-1.72250	66.32230	64.45610	HepG2	RBM22
ALDOA	ENSG00000149925.12	15464.51830	27441.68580	-0.82740	66.10030	63.75630	HepG2	ZC3H8
ALDOA	ENSG00000149925.12	12975.44910	42927.80930	-1.72610	56.04100	54.46090	HepG2	SSB
ALDOA	ENSG00000149925.12	56381.69640	36845.34130	0.61360	44.72150	42.41400	HepG2	HNRNPL
ALDOA	ENSG00000149925.12	25724.50450	59584.88110	-1.21180	43.77630	42.20430	HepG2	NELFE
ALDOA	ENSG00000149925.12	23573.99600	53542.05220	-1.18350	43.68970	42.06860	HepG2	PTBP1
ALDOA	ENSG00000149925.12	25083.11070	55499.35890	-1.14580	42.68030	40.83590	HepG2	RECQL
ALDOA	ENSG00000149925.12	23190.91570	40647.47610	-0.80960	39.76680	38.05800	HepG2	PUM1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 166 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ALDOA is not available on ENCORE database.

61 RBPs can affect the splicing of ALDOA :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	-0.16700	0.00000	excluded	K562	TAF15
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.10900	0.00050	included	HepG2	G3BP1
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.17900	0.00000	included	K562	IGF2BP2
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.13800	0.00284	included	K562	RPS3
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.11200	0.00043	included	K562	FTO
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.11900	0.00008	included	K562	SF3B4
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078679	0.16500	0.00000	included	K562	TIA1
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30076059	30076105	30078554	30078687	0.07900	0.00134	included	HepG2	DDX59
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.12700	0.00003	included	K562	METAP2
SE	ALDOA	ENSG00000149925.12	chr16	+	30077196	30077248	30075744	30075826	30078554	30078687	0.08100	0.00091	included	HepG2	SRSF7

Showing 1 to 10 of 74 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ALDOA

General Information

Functions

Localization

Domains (AlphaFold: ALDOA)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ALDOA is not avaliable on ENCORE database.

39 proteins are bound to ALDOA RNA:

eCLIP assay for ALDOA is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ALDOA is not available on ENCORE database.

137 RBPs can affect the gene expression of ALDOA :

The Knockdown/knockout RNA-Seq assay for ALDOA is not available on ENCORE database.

61 RBPs can affect the splicing of ALDOA :

The Knockdown/knockout RNA-Seq assay for ALDOA is not avaliable on ENCORE database.