HNF1A

General Information

Gene Name : HNF1A
Gene ID : ENSG00000135100.17
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HNF1A)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HNF1A	ENSG00000135100.17	0.00	0.00	0.00	ENCSR000AEF
HepG2	HNF1A	ENSG00000135100.17	47.99	12.35	30.17	ENCSR985KAT
K562	HNF1A	ENSG00000135100.17	0.00	0.00	0.00	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HNF1A is not avaliable on ENCORE database.

Proteins bound to RNA

HNF1A RNA is bound by 20 proteins.

eCLIP assay for HNF1A is not avaliable on ENCORE database.

20 proteins are bound to HNF1A RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	121431966	121432010	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.23463	7.05872	HepG2	PPIG
chr12	121426634	121426664	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.00516	3.47879	HepG2	PPIG
chr12	121435367	121435469	+	3'-UTR,CDS,intron-Proximal	3.02894	4.18458	HepG2	G3BP1
chr12	121439787	121439885	+	3'-UTR	4.80357	6.92572	HepG2	AKAP1
chr12	121438999	121439113	+	3'-UTR	4.54628	4.78280	HepG2	AKAP1
chr12	121431436	121431507	+	3'-UTR,CDS,intron-Distal	4.00191	3.32571	HepG2	AGGF1
chr12	121438992	121439103	+	3'-UTR	4.25464	8.55060	HepG2	UPF1
chr12	121431507	121431586	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.19357	4.26705	HepG2	AGGF1
chr12	121438840	121438922	+	3'-UTR,CDS,intron-Proximal	3.55642	8.84055	HepG2	BUD13
chr12	121439702	121439779	+	3'-UTR	4.70603	5.97422	HepG2	AKAP1
chr12	121434506	121434623	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.31281	16.31899	HepG2	PRPF8
chr12	121431439	121431497	+	3'-UTR,CDS,intron-Distal	3.28442	3.97184	HepG2	G3BP1
chr12	121434029	121434086	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.30063	4.49790	HepG2	AGGF1
chr12	121431417	121431493	+	3'-UTR,CDS,intron-Distal	3.28136	4.02291	HepG2	GRWD1
chr12	121435216	121435301	+	3'-UTR,CDS,intron-Proximal	3.95529	17.71550	HepG2	BUD13
chr12	121435244	121435314	+	3'-UTR,CDS,intron-Proximal	5.07499	6.74224	HepG2	AQR
chr12	121426588	121426666	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.98599	7.09786	HepG2	AQR
chr12	121439787	121439854	+	3'-UTR	3.13966	3.22540	HepG2	G3BP1
chr12	121439489	121439657	+	3'-UTR	5.47222	9.16654	HepG2	UPF1
chr12	121434139	121434217	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.24243	6.00788	HepG2	PPIG
chr12	121426639	121426721	+	3'-UTR,CDS,intron-Distal	3.12404	5.18023	HepG2	GRWD1
chr12	121439775	121439874	+	3'-UTR	4.34172	9.30447	HepG2	UPF1
chr12	121439128	121439240	+	3'-UTR	4.16430	5.91795	HepG2	UPF1
chr12	121439706	121439763	+	3'-UTR	3.74074	5.64093	HepG2	UPF1
chr12	121431966	121432047	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.56996	5.14242	HepG2	G3BP1
chr12	121439447	121439505	+	3'-UTR	3.60077	6.16249	HepG2	RBM15
chr12	121435518	121435573	+	3'-UTR,CDS,intron-Distal,intron-Proximal	3.13905	3.38325	HepG2	IGF2BP1
chr12	121439874	121439944	+	3'-UTR	4.53969	5.07111	HepG2	UPF1
chr12	121416514	121416560	+	5'-UTR,CDS,intron-Proximal	3.50603	3.85482	HepG2	CDC40
chr12	121416818	121416888	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.51342	7.36645	HepG2	PPIG
chr12	121416518	121416570	+	5'-UTR,CDS,intron-Proximal	5.64135	12.16529	HepG2	PRPF4
chr12	121416437	121416515	+	5'-UTR,CDS,intron-Proximal	5.03743	33.54367	HepG2	PRPF4
chr12	121416521	121416582	+	5'-UTR,CDS,intron-Proximal	3.26775	5.47379	HepG2	EIF3H
chr12	121416378	121416437	+	5'-UTR,CDS	5.80171	15.54949	HepG2	PRPF4
chr12	121416829	121416880	+	5'-UTR,CDS,intron-Distal,intron-Proximal	4.17664	4.91614	HepG2	GRWD1
chr12	121416871	121416934	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.96173	13.56212	HepG2	PRPF8
chr12	121416880	121416937	+	5'-UTR,CDS,intron-Distal,intron-Proximal	3.10563	3.60157	HepG2	GRWD1
chr12	121416452	121416550	+	5'-UTR,CDS,intron-Proximal	3.91051	5.04492	HepG2	FTO
chr12	121416392	121416516	+	5'-UTR,CDS,intron-Proximal	5.27126	16.62109	HepG2	GTF2F1
chr12	121426682	121426744	+	CDS,intron-Distal	3.17667	3.47314	HepG2	G3BP1
chr12	121425769	121425778	+	intron-Distal	3.97148	4.28120	HepG2	AGGF1
chr12	121433108	121433166	+	intron-Distal	4.25741	4.69321	HepG2	GTF2F1
chr12	121432544	121432595	+	intron-Distal	5.84546	16.05207	HepG2	AGGF1
chr12	121433023	121433134	+	intron-Distal	4.87745	24.04896	HepG2	HNRNPL
chr12	121432939	121433002	+	intron-Distal	6.45702	21.51730	HepG2	AGGF1
chr12	121418170	121418240	+	intron-Distal	3.46921	4.35063	HepG2	PRPF4
chr12	121433772	121433864	+	intron-Distal	3.67445	3.10765	HepG2	YBX3
chr12	121433394	121433432	+	intron-Distal	4.04926	5.48327	HepG2	XPO5
chr12	121426276	121426388	+	intron-Distal	5.65908	9.31915	HepG2	GTF2F1
chr12	121433495	121433565	+	intron-Distal	4.92793	8.70712	HepG2	XPO5
chr12	121432360	121432439	+	intron-Distal	4.11501	14.39850	HepG2	HNRNPL
chr12	121433604	121433696	+	intron-Distal	4.50741	20.67848	HepG2	HNRNPL
chr12	121433031	121433131	+	intron-Distal	5.04209	6.62423	HepG2	XPO5
chr12	121433460	121433550	+	intron-Distal	4.59118	18.60858	HepG2	HNRNPL
chr12	121432480	121432544	+	intron-Distal	5.11982	15.23686	HepG2	AGGF1
chr12	121418490	121418532	+	intron-Distal	4.68195	6.19628	HepG2	FAM120A
chr12	121425988	121426006	+	intron-Distal	3.87352	13.02866	HepG2	AGGF1
chr12	121433626	121433681	+	intron-Distal	4.59381	9.67555	HepG2	AGGF1
chr12	121426310	121426394	+	intron-Distal	5.76678	14.73237	HepG2	AGGF1
chr12	121433371	121433460	+	intron-Distal	5.84525	21.85136	HepG2	HNRNPL
chr12	121425681	121425715	+	intron-Distal	3.77126	4.14912	HepG2	AGGF1
chr12	121432255	121432276	+	intron-Distal,intron-Proximal	4.21781	5.43961	HepG2	AGGF1
chr12	121432535	121432584	+	intron-Distal	4.12791	10.24078	HepG2	HNRNPL
chr12	121433256	121433371	+	intron-Distal	4.81048	19.30342	HepG2	HNRNPL
chr12	121426114	121426203	+	intron-Distal	4.78485	6.40009	HepG2	GTF2F1
chr12	121432654	121432725	+	intron-Distal	4.65721	15.86690	HepG2	HNRNPL
chr12	121433646	121433689	+	intron-Distal	4.08689	3.58513	HepG2	GTF2F1
chr12	121418416	121418531	+	intron-Distal	5.19264	7.86574	HepG2	GTF2F1
chr12	121433639	121433699	+	intron-Distal	5.67708	7.96764	HepG2	XPO5
chr12	121426103	121426228	+	intron-Distal	4.07247	8.19245	HepG2	HNRNPL
chr12	121432883	121432939	+	intron-Distal	4.89770	12.78144	HepG2	AGGF1
chr12	121425969	121425988	+	intron-Distal	3.87352	13.02866	HepG2	AGGF1
chr12	121433300	121433327	+	intron-Distal	5.24331	5.81375	HepG2	XPO5
chr12	121426228	121426327	+	intron-Distal	3.87182	12.70351	HepG2	HNRNPL
chr12	121433002	121433183	+	intron-Distal	5.88032	40.87503	HepG2	AGGF1
chr12	121432725	121432826	+	intron-Distal	5.75974	24.03652	HepG2	HNRNPL
chr12	121426115	121426370	+	intron-Distal	5.47932	15.01627	HepG2	YBX3
chr12	121433283	121433367	+	intron-Distal	5.70845	21.81053	HepG2	AGGF1
chr12	121418611	121418684	+	intron-Distal	4.78092	7.58609	HepG2	PRPF4
chr12	121426119	121426203	+	intron-Distal	5.13258	18.98420	HepG2	XPO5
chr12	121432818	121432863	+	intron-Distal	3.16099	4.68227	HepG2	AGGF1
chr12	121432462	121432535	+	intron-Distal	4.96174	12.49294	HepG2	HNRNPL
chr12	121426203	121426362	+	intron-Distal	6.65273	33.77283	HepG2	XPO5
chr12	121433184	121433283	+	intron-Distal	5.52125	21.10121	HepG2	AGGF1
chr12	121425778	121425812	+	intron-Distal	4.68328	9.18778	HepG2	AGGF1
chr12	121433367	121433468	+	intron-Distal	4.83935	22.22815	HepG2	AGGF1
chr12	121426106	121426225	+	intron-Distal	5.53335	49.06786	HepG2	AGGF1
chr12	121426226	121426334	+	intron-Distal	4.71310	10.22899	HepG2	CDC40
chr12	121432385	121432480	+	intron-Distal	4.18369	13.80220	HepG2	AGGF1
chr12	121432919	121433031	+	intron-Distal	5.14154	8.18285	HepG2	XPO5
chr12	121432657	121432811	+	intron-Distal	4.96685	27.48503	HepG2	AGGF1
chr12	121418436	121418536	+	intron-Distal	3.25388	7.70093	HepG2	PRPF4
chr12	121432866	121432968	+	intron-Distal	4.35808	15.18239	HepG2	HNRNPL
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for HNF1A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HNF1A is not available on ENCORE database.
63 RBPs can affect the levels of HNF1A.

The Knockdown/knockout RNA-Seq assay for HNF1A is not available on ENCORE database.

63 RBPs can affect the gene expression of HNF1A :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HNF1A	ENSG00000135100.13	271.88680	537.95280	-0.98450	4.45420	3.12320	HepG2	AATF
HNF1A	ENSG00000135100.13	566.94230	1163.28380	-1.03690	29.01300	27.53830	HepG2	ACO1
HNF1A	ENSG00000135100.13	369.92730	1445.73640	-1.96650	12.32950	11.28640	HepG2	AKAP1
HNF1A	ENSG00000135100.13	1361.12120	1687.31780	-0.30990	3.90440	3.11430	HepG2	AUH
HNF1A	ENSG00000135100.13	1431.27520	1156.81260	0.30700	2.21860	1.67710	HepG2	BOP1
HNF1A	ENSG00000135100.13	620.66540	930.54230	-0.58430	2.72220	1.95670	HepG2	CALR
HNF1A	ENSG00000135100.13	756.28290	478.48110	0.66040	4.96630	3.60460	HepG2	YBX3
HNF1A	ENSG00000135100.13	939.15680	752.97830	0.31870	2.77910	2.13580	HepG2	CELF1
HNF1A	ENSG00000135100.13	647.20560	479.10660	0.43380	3.03470	1.82630	HepG2	DDX1
HNF1A	ENSG00000135100.13	822.63560	1205.97960	-0.55190	2.58980	1.64620	HepG2	DDX59
HNF1A	ENSG00000135100.13	1358.54800	1112.95060	0.28760	3.04210	2.33610	HepG2	DKC1
HNF1A	ENSG00000135100.13	825.12880	469.77300	0.81260	5.33540	4.38630	HepG2	DNAJC21
HNF1A	ENSG00000135100.13	920.53250	465.71130	0.98290	19.62380	18.03750	HepG2	DNAJC2
HNF1A	ENSG00000135100.13	1485.02050	1937.37280	-0.38360	3.48440	2.82170	HepG2	ETF1
HNF1A	ENSG00000135100.13	1245.42870	1832.30450	-0.55700	4.80950	3.81760	HepG2	FIP1L1
HNF1A	ENSG00000135100.13	1054.13960	1282.72840	-0.28310	2.17220	1.46820	HepG2	FUBP3
HNF1A	ENSG00000135100.13	908.77250	574.44760	0.66160	2.55690	1.70070	HepG2	GEMIN5
HNF1A	ENSG00000135100.13	1532.35930	1203.78920	0.34810	2.20950	1.63420	HepG2	GPKOW
HNF1A	ENSG00000135100.13	767.74510	474.27450	0.69480	7.16120	6.19440	HepG2	HNRNPA1
HNF1A	ENSG00000135100.13	1350.66100	867.55460	0.63850	11.89350	10.54780	HepG2	HNRNPF
HNF1A	ENSG00000135100.13	1171.37820	737.57240	0.66730	13.88970	12.48800	HepG2	HNRNPL
HNF1A	ENSG00000135100.13	973.01590	524.08140	0.89260	18.91530	17.44080	HepG2	HNRNPU
HNF1A	ENSG00000135100.13	1189.87110	854.29000	0.47790	4.88340	3.94760	HepG2	IGF2BP1
HNF1A	ENSG00000135100.13	692.87840	535.32680	0.37210	3.38740	2.58240	HepG2	ILF2
HNF1A	ENSG00000135100.13	1344.30130	1063.39520	0.33810	4.89820	3.54680	HepG2	KIF1C
HNF1A	ENSG00000135100.13	903.57330	576.87960	0.64730	2.77470	1.55890	HepG2	LIN28B
HNF1A	ENSG00000135100.13	1766.61310	1275.94530	0.46930	1.98010	1.42070	HepG2	MAGOH
HNF1A	ENSG00000135100.13	1235.56070	1482.72100	-0.26310	2.04790	1.34650	HepG2	MSI2
HNF1A	ENSG00000135100.13	1265.78130	802.87680	0.65670	5.86620	4.75880	HepG2	NOL12
HNF1A	ENSG00000135100.13	1369.22430	649.19800	1.07650	8.95380	6.40560	HepG2	NOLC1
HNF1A	ENSG00000135100.13	883.36910	482.17500	0.87340	5.79140	3.56010	HepG2	PA2G4
HNF1A	ENSG00000135100.13	936.17610	533.60350	0.81090	5.16360	3.50310	HepG2	PKM
HNF1A	ENSG00000135100.13	1134.61840	467.43370	1.27930	16.40800	14.69960	HepG2	PPIL4
HNF1A	ENSG00000135100.13	1033.13030	1283.78590	-0.31340	3.46270	2.60730	HepG2	PRPF4
HNF1A	ENSG00000135100.13	1038.20840	1253.70540	-0.27210	2.52710	2.00020	HepG2	PTBP1
HNF1A	ENSG00000135100.13	1178.90500	766.40350	0.62120	7.33440	6.42320	HepG2	PUF60
HNF1A	ENSG00000135100.13	1397.93160	813.55630	0.78090	21.46310	20.12890	HepG2	PUM1
HNF1A	ENSG00000135100.13	1074.88650	812.97130	0.40280	3.75360	2.97810	HepG2	PUM2
HNF1A	ENSG00000135100.13	1013.53820	620.13420	0.70860	3.33730	1.44100	HepG2	RBM14
HNF1A	ENSG00000135100.13	746.84260	1619.26300	-1.11650	30.58940	29.23340	HepG2	RBM22
HNF1A	ENSG00000135100.13	1030.21770	663.03790	0.63570	2.36640	1.45740	HepG2	RBM27
HNF1A	ENSG00000135100.13	982.59140	627.95260	0.64580	4.78980	4.00580	HepG2	RPS19
HNF1A	ENSG00000135100.13	866.88300	548.54190	0.66010	1.98360	1.30660	HepG2	RPS3A
HNF1A	ENSG00000135100.13	1048.26330	466.70070	1.16730	29.97750	28.18000	HepG2	SAFB2
HNF1A	ENSG00000135100.13	1236.33380	553.03380	1.16050	2.78140	1.42460	HepG2	SF1
HNF1A	ENSG00000135100.13	1430.89750	1137.05230	0.33150	2.46780	1.79870	HepG2	SF3B1
HNF1A	ENSG00000135100.13	1325.37250	734.83090	0.85080	22.96150	21.33050	HepG2	SLBP
HNF1A	ENSG00000135100.13	858.98980	544.22340	0.65830	11.36390	10.19840	HepG2	SMN1
HNF1A	ENSG00000135100.13	1151.28160	495.36530	1.21660	3.28320	1.82870	HepG2	SNRNP200
HNF1A	ENSG00000135100.13	937.87950	1828.85880	-0.96350	33.36880	32.13180	HepG2	SRFBP1
HNF1A	ENSG00000135100.13	852.53530	1362.39530	-0.67630	13.30060	12.42980	HepG2	SRSF1
HNF1A	ENSG00000135100.13	1203.46050	756.69400	0.66930	9.84470	8.76060	HepG2	SRSF5
HNF1A	ENSG00000135100.13	1202.04740	852.35610	0.49590	7.39120	6.34100	HepG2	SRSF7
HNF1A	ENSG00000135100.13	692.29900	1108.39400	-0.67900	12.98770	11.94920	HepG2	SRSF9
HNF1A	ENSG00000135100.13	1298.69450	860.58480	0.59360	11.35530	10.24050	HepG2	SUCLG1
HNF1A	ENSG00000135100.13	523.95490	1224.61520	-1.22480	25.50110	24.03100	HepG2	TAF15
HNF1A	ENSG00000135100.13	1442.09390	1119.89660	0.36470	2.84900	2.11580	HepG2	TARDBP
HNF1A	ENSG00000135100.13	980.98800	509.13530	0.94610	16.42830	15.39250	HepG2	TIAL1
HNF1A	ENSG00000135100.13	1079.82800	513.80220	1.07140	14.04410	12.91330	HepG2	TRIM56
HNF1A	ENSG00000135100.13	1656.49800	748.71950	1.14550	6.94990	5.46520	HepG2	TUFM
HNF1A	ENSG00000135100.13	832.04390	491.38000	0.75970	2.51300	1.47510	HepG2	XPO5
HNF1A	ENSG00000135100.13	1002.97480	595.32950	0.75240	3.11200	2.34430	HepG2	XRN2
HNF1A	ENSG00000135100.13	987.64390	1266.89300	-0.35920	4.91180	4.06030	HepG2	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HNF1A is not available on ENCORE database.

5 RBPs can affect the splicing of HNF1A :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	HNF1A	ENSG00000135100.13	chr12	+	121437264	121437430	121437285	121437430	121437070	121437192	0.14200	0.00012	0.01391	longer	HepG2	SF3A3
A3SS	HNF1A	ENSG00000135100.13	chr12	+	121437264	121437430	121437285	121437430	121437070	121437192	0.57700	0.00000	0.00000	longer	HepG2	RBM22
A5SS	HNF1A	ENSG00000135100.13	chr12	+	121426635	121426835	121426635	121426803	121431322	121431509	-0.09900	0.00031	0.03982	shorter	HepG2	TAF15
RI	HNF1A	ENSG00000135100.13	chr12	+	121437070	121437430	121437070	121437192	121437285	121437430	0.12300	0.00012	0.00227	included	HepG2	SF3A3
RI	HNF1A	ENSG00000135100.13	chr12	+	121437070	121437430	121437070	121437192	121437264	121437430	0.21800	0.00486	0.08562	included	HepG2	FTO
RI	HNF1A	ENSG00000135100.13	chr12	+	121437070	121437430	121437070	121437192	121437285	121437430	0.52500	0.00000	0.00000	included	HepG2	RBM22
RI	HNF1A	ENSG00000135100.13	chr12	+	121434343	121436103	121434343	121434545	121435276	121436103	0.09000	0.00048	0.00686	included	HepG2	RBM22
RI	HNF1A	ENSG00000135100.13	chr12	+	121437070	121437430	121437070	121437192	121437264	121437430	0.14800	0.00114	0.05581	included	HepG2	LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HNF1A

General Information

Functions

Localization

Domains (AlphaFold: HNF1A)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HNF1A is not avaliable on ENCORE database.

20 proteins are bound to HNF1A RNA:

eCLIP assay for HNF1A is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HNF1A is not available on ENCORE database.

63 RBPs can affect the gene expression of HNF1A :

The Knockdown/knockout RNA-Seq assay for HNF1A is not available on ENCORE database.

5 RBPs can affect the splicing of HNF1A :

The Knockdown/knockout RNA-Seq assay for HNF1A is not avaliable on ENCORE database.