FXN

General Information

Gene Name : FXN
Gene ID : ENSG00000165060.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: FXN)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	FXN	ENSG00000165060.12	25.11	22.17	23.64	ENCSR000AEF
HepG2	FXN	ENSG00000165060.12	42.17	55.34	48.76	ENCSR985KAT
K562	FXN	ENSG00000165060.12	32.16	34.66	33.41	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for FXN is not avaliable on ENCORE database.

Proteins bound to RNA

FXN RNA is bound by 10 proteins.

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eCLIP assay for FXN is not avaliable on ENCORE database.

10 proteins are bound to FXN RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	71683367	71683471	+	intron-Distal	5.24442	8.16466	K562	SLTM
chr9	71650697	71650864	+	5'-UTR,CDS,intron-Proximal	4.29247	7.94128	HepG2	DDX3X
chr9	71679894	71679953	+	CDS,intron-Proximal	3.18888	7.59396	K562	YBX3
chr9	71681959	71682046	+	intron-Distal	3.85082	5.57381	HepG2	SLTM
chr9	71685324	71685419	+	intron-Distal	4.58771	5.09502	K562	SLTM
chr9	71682987	71683071	+	intron-Distal	3.74867	5.08142	K562	SLTM
chr9	71664942	71665032	+	intron-Distal	4.53752	5.05488	HepG2	QKI
chr9	71687781	71687859	+	3'-UTR,intron-Distal	4.32005	4.97297	K562	TIA1
chr9	71681956	71682028	+	intron-Distal	3.81743	4.19798	K562	SLTM
chr9	71684469	71684519	+	intron-Distal	4.33646	4.14527	K562	SLTM
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 17 entries

eCLIP assay for FXN is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for FXN is not available on ENCORE database.
62 RBPs can affect the levels of FXN.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.

62 RBPs can affect the gene expression of FXN :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
FXN	ENSG00000165060.7	94.72890	389.83160	-2.04100	24.19840	22.31700	HepG2	G3BP1
FXN	ENSG00000165060.7	102.41830	376.88790	-1.87970	20.08350	18.58590	HepG2	EIF2S1
FXN	ENSG00000165060.7	159.36620	370.66640	-1.21780	15.17870	13.81090	HepG2	ZC3H8
FXN	ENSG00000165060.7	120.98890	372.62450	-1.62280	14.93900	13.58480	HepG2	SUPV3L1
FXN	ENSG00000165060.7	341.85660	651.78250	-0.93100	14.35560	13.45150	HepG2	SRFBP1
FXN	ENSG00000165060.7	167.28340	397.64520	-1.24920	10.59130	9.39600	HepG2	GPKOW
FXN	ENSG00000165060.7	421.64810	229.94330	0.87470	8.65120	7.65360	K562	FXR1
FXN	ENSG00000165060.7	124.85200	288.73310	-1.20950	8.50670	7.17630	HepG2	PRPF8
FXN	ENSG00000165060.7	136.51760	284.12140	-1.05740	8.48040	6.89970	HepG2	SUPT6H
FXN	ENSG00000165060.7	236.00690	495.45430	-1.06990	8.51270	6.80200	HepG2	CCAR1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 67 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.

4 RBPs can affect the splicing of FXN :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	FXN	ENSG00000165060.7	chr9	+	71668055	71668176	71661300	71661398	71679853	71679959	-0.08600	0.00001	0.00022	excluded	HepG2	U2AF2
SE	FXN	ENSG00000165060.7	chr9	+	71668055	71668176	71661300	71661398	71679853	71679959	-0.12600	0.00006	0.00550	excluded	K562	EFTUD2
SE	FXN	ENSG00000165060.7	chr9	+	71687527	71687746	71679853	71679951	71714816	71715094	-0.20300	0.00258	0.04470	excluded	K562	SRSF1
SE	FXN	ENSG00000165060.7	chr9	+	71687527	71687746	71679853	71679951	71714816	71715094	0.19400	0.00355	0.05686	included	K562	SF3B4
SE	FXN	ENSG00000165060.7	chr9	+	71687527	71687746	71679853	71679951	71714816	71715094	0.24600	0.00377	0.05775	included	K562	U2AF2
SE	FXN	ENSG00000165060.7	chr9	+	71668055	71668176	71661300	71661398	71679853	71679959	-0.09500	0.00669	0.09047	excluded	K562	U2AF2

Showing 1 to 6 of 6 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

FXN

General Information

Functions

Localization

Domains (AlphaFold: FXN)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for FXN is not avaliable on ENCORE database.

10 proteins are bound to FXN RNA:

eCLIP assay for FXN is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.

62 RBPs can affect the gene expression of FXN :

The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.

4 RBPs can affect the splicing of FXN :

The Knockdown/knockout RNA-Seq assay for FXN is not avaliable on ENCORE database.