ERCC8

General Information

Gene Name : ERCC8
Gene ID : ENSG00000049167.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ERCC8)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ERCC8	ENSG00000049167.14	10.82	9.46	10.14	ENCSR000AEF
HepG2	ERCC8	ENSG00000049167.14	11.70	20.06	15.88	ENCSR985KAT
K562	ERCC8	ENSG00000049167.14	13.83	13.70	13.77	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ERCC8 is not avaliable on ENCORE database.

Proteins bound to RNA

ERCC8 RNA is bound by 9 proteins.

CanvasJS.com

eCLIP assay for ERCC8 is not avaliable on ENCORE database.

9 proteins are bound to ERCC8 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr5	60212596	60212722	-	intron-Distal	5.34790	10.09004	HepG2	QKI
chr5	60228597	60228711	-	intron-Distal	5.08148	6.57498	HepG2	PCBP2
chr5	60195450	60195528	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.08355	5.35431	HepG2	BCLAF1
chr5	60213926	60214095	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.59195	5.33214	K562	PRPF8
chr5	60217877	60217925	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.58887	4.74886	HepG2	BCLAF1
chr5	60210560	60210619	-	intron-Distal	4.12999	4.37667	K562	SAFB2
chr5	60194116	60194176	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.39905	4.34695	HepG2	BCLAF1
chr5	60186988	60187087	-	intron-Distal,intron-Proximal	3.95313	3.90026	K562	KHSRP
chr5	60214158	60214215	-	5'-UTR,CDS,intron-Distal	3.14498	3.85381	HepG2	BCLAF1
chr5	60223956	60224077	-	intron-Distal	4.03891	3.48210	HepG2	HNRNPL
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 14 entries

eCLIP assay for ERCC8 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ERCC8 is not available on ENCORE database.
77 RBPs can affect the levels of ERCC8.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ERCC8 is not available on ENCORE database.

77 RBPs can affect the gene expression of ERCC8 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ERCC8	ENSG00000049167.9	177.01380	430.02860	-1.28060	17.92870	16.59950	HepG2	PCBP1
ERCC8	ENSG00000049167.9	129.38590	320.15140	-1.30710	16.66020	15.03710	HepG2	ILF2
ERCC8	ENSG00000049167.9	106.12800	278.48320	-1.39180	15.72240	14.29470	HepG2	DNAJC2
ERCC8	ENSG00000049167.9	158.33920	393.10490	-1.31190	11.84910	10.67470	HepG2	EIF2S1
ERCC8	ENSG00000049167.9	338.30070	598.88530	-0.82400	11.45860	10.62750	HepG2	SRFBP1
ERCC8	ENSG00000049167.9	218.01000	412.84250	-0.92120	10.62640	9.38530	HepG2	HNRNPL
ERCC8	ENSG00000049167.9	159.19380	335.94320	-1.07740	10.12480	9.12850	K562	AGGF1
ERCC8	ENSG00000049167.9	158.37360	337.77970	-1.09280	10.07970	8.97290	K562	RBM15
ERCC8	ENSG00000049167.9	164.72620	349.55860	-1.08550	9.50950	8.21150	K562	AKAP8L
ERCC8	ENSG00000049167.9	183.39660	408.92790	-1.15690	9.10210	8.05100	HepG2	DDX6
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 85 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ERCC8 is not available on ENCORE database.

6 RBPs can affect the splicing of ERCC8 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	ERCC8	ENSG00000049167.9	chr5	-	60227933	60227975	60224690	60224786	60240758	60240900	0.18900	0.00001	0.00155	included	K562	XRCC6
A3SS	ERCC8	ENSG00000049167.9	chr5	-	60198268	60198414	60198268	60198335	60199474	60199543	0.12100	0.00001	0.00013	longer	K562	AQR
SE	ERCC8	ENSG00000049167.9	chr5	-	60220117	60220256	60217880	60217982	60224690	60224786	0.13500	0.00004	0.00562	included	HepG2	HNRNPL
SE	ERCC8	ENSG00000049167.9	chr5	-	60186715	60186913	60183266	60183347	60194102	60194227	-0.21900	0.00009	0.01021	excluded	HepG2	HNRNPL
SE	ERCC8	ENSG00000049167.9	chr5	-	60227933	60227975	60224690	60224786	60240758	60240900	0.11300	0.00045	0.08765	included	HepG2	FUS
SE	ERCC8	ENSG00000049167.9	chr5	-	60220117	60220335	60217880	60217982	60224690	60224786	-0.06500	0.00196	0.09160	excluded	HepG2	NCBP2
SE	ERCC8	ENSG00000049167.9	chr5	-	60186099	60186228	60183266	60183347	60186715	60186913	0.30300	0.00273	0.04349	included	K562	HNRNPC
A3SS	ERCC8	ENSG00000049167.9	chr5	-	60195453	60195622	60195453	60195554	60198268	60198335	0.05900	0.01251	0.06403	longer	K562	AQR

Showing 1 to 8 of 8 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ERCC8

General Information

Functions

Localization

Domains (AlphaFold: ERCC8)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ERCC8 is not avaliable on ENCORE database.

9 proteins are bound to ERCC8 RNA:

eCLIP assay for ERCC8 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ERCC8 is not available on ENCORE database.

77 RBPs can affect the gene expression of ERCC8 :

The Knockdown/knockout RNA-Seq assay for ERCC8 is not available on ENCORE database.

6 RBPs can affect the splicing of ERCC8 :

The Knockdown/knockout RNA-Seq assay for ERCC8 is not avaliable on ENCORE database.