LEMD1

General Information

Gene Name : LEMD1
Gene ID : ENSG00000186007.9
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: LEMD1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	LEMD1	ENSG00000186007.9	0.00	0.04	0.02	ENCSR000AEF
HepG2	LEMD1	ENSG00000186007.9	1.06	0.29	0.68	ENCSR985KAT
K562	LEMD1	ENSG00000186007.9	0.57	0.79	0.68	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for LEMD1 is not avaliable on ENCORE database.

Proteins bound to RNA

LEMD1 RNA is bound by 11 proteins.

eCLIP assay for LEMD1 is not avaliable on ENCORE database.

11 proteins are bound to LEMD1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	205418951	205418998	-	5'-UTR,intron-Distal	6.84114	52.26183	HepG2	DGCR8
chr1	205418996	205419020	-	5'-UTR,intron-Distal	5.82396	20.11716	HepG2	DROSHA
chr1	205418962	205419035	-	5'-UTR,intron-Distal	5.13344	9.04913	K562	DROSHA
chr1	205419020	205419062	-	5'-UTR,intron-Distal,intron-Proximal	5.08968	9.59854	HepG2	DROSHA
chr1	205418998	205419047	-	5'-UTR,intron-Distal	6.74213	45.57759	HepG2	DGCR8
chr1	205418964	205419060	-	5'-UTR,intron-Distal,intron-Proximal	3.82938	5.29681	HepG2	NCBP2
chr1	205417091	205417171	-	intron-Distal	6.79970	22.41747	HepG2	DROSHA
chr1	205417502	205417614	-	intron-Distal	7.81373	54.98208	K562	DGCR8
chr1	205418947	205418996	-	intron-Distal	7.07716	28.04128	HepG2	DROSHA
chr1	205417252	205417333	-	intron-Distal	5.52384	20.08501	HepG2	DROSHA
chr1	205418263	205418312	-	intron-Distal	4.81949	10.60725	HepG2	DROSHA
chr1	205417750	205417794	-	intron-Distal	7.44571	38.83364	HepG2	DGCR8
chr1	205417510	205417631	-	intron-Distal	6.01196	74.28399	HepG2	DROSHA
chr1	205416577	205416606	-	intron-Distal	6.22862	17.19491	HepG2	DGCR8
chr1	205417361	205417411	-	intron-Distal	7.49090	46.06736	HepG2	DGCR8
chr1	205417576	205417627	-	intron-Distal	4.58219	4.31089	HepG2	FKBP4
chr1	205417268	205417328	-	intron-Distal	4.38880	4.24247	HepG2	CDC40
chr1	205416918	205416951	-	intron-Distal	5.53775	19.31437	HepG2	DGCR8
chr1	205416687	205416832	-	intron-Distal	3.75209	5.59440	HepG2	HNRNPK
chr1	205416631	205416700	-	intron-Distal	3.73990	4.81093	HepG2	DROSHA
chr1	205417578	205417598	-	intron-Distal	9.12484	133.97638	HepG2	DGCR8
chr1	205417598	205417623	-	intron-Distal	8.76526	101.24466	HepG2	DGCR8
chr1	205418532	205418600	-	intron-Distal	6.69461	70.98121	HepG2	DGCR8
chr1	205418282	205418366	-	intron-Distal	6.85819	63.24659	HepG2	DGCR8
chr1	205417623	205417667	-	intron-Distal	6.49005	41.51985	HepG2	DGCR8
chr1	205416642	205416696	-	intron-Distal	6.03691	36.08396	HepG2	DGCR8
chr1	205417889	205417916	-	intron-Distal	5.63287	8.62876	HepG2	DROSHA
chr1	205417448	205417491	-	intron-Distal	7.53197	41.49864	K562	DGCR8
chr1	205418779	205418839	-	intron-Distal	6.67302	22.88739	HepG2	DROSHA
chr1	205417329	205417361	-	intron-Distal	8.76177	102.90735	HepG2	DGCR8
chr1	205417141	205417165	-	intron-Distal	6.54953	36.79102	HepG2	DGCR8
chr1	205417564	205417578	-	intron-Distal	8.98796	119.93488	HepG2	DGCR8
chr1	205417753	205417789	-	intron-Distal	6.13249	14.45177	HepG2	DROSHA
chr1	205417084	205417117	-	intron-Distal	6.10641	26.67424	HepG2	DGCR8
chr1	205418602	205418657	-	intron-Distal	6.69694	20.25727	HepG2	DROSHA
chr1	205418479	205418532	-	intron-Distal	6.59063	44.24553	HepG2	DGCR8
chr1	205417667	205417701	-	intron-Distal	5.53662	22.24728	HepG2	DGCR8
chr1	205416710	205416764	-	intron-Distal	6.89583	27.42832	HepG2	DGCR8
chr1	205417183	205417206	-	intron-Distal	5.04810	6.56353	K562	DGCR8
chr1	205418541	205418651	-	intron-Distal	6.88469	13.47900	K562	DROSHA
chr1	205418550	205418611	-	intron-Distal	6.09020	15.81616	K562	DGCR8
chr1	205418163	205418199	-	intron-Distal	6.08325	27.75485	HepG2	DGCR8
chr1	205416660	205416697	-	intron-Distal	5.23736	8.75803	K562	DGCR8
chr1	205416850	205416901	-	intron-Distal	6.20535	35.17102	HepG2	DGCR8
chr1	205417252	205417361	-	intron-Distal	7.24696	35.42909	K562	DGCR8
chr1	205417515	205417556	-	intron-Distal	3.44249	6.36032	HepG2	NKRF
chr1	205417552	205417564	-	intron-Distal	8.72779	97.66340	HepG2	DGCR8
chr1	205418664	205418791	-	intron-Distal	5.83636	50.31002	HepG2	DGCR8
chr1	205416310	205416327	-	intron-Distal	5.32701	11.51361	HepG2	DGCR8
chr1	205416282	205416310	-	intron-Distal	4.84494	14.00250	HepG2	DGCR8
chr1	205418073	205418130	-	intron-Distal	5.28999	23.07331	HepG2	DGCR8
chr1	205416951	205416998	-	intron-Distal	5.81383	33.04980	HepG2	DGCR8
chr1	205409040	205409110	-	intron-Distal	3.50090	4.35255	HepG2	PCBP2
chr1	205418532	205418602	-	intron-Distal	5.69244	25.82436	HepG2	DROSHA
chr1	205418516	205418654	-	intron-Distal	4.58226	5.44815	HepG2	PRPF4
chr1	205417517	205417658	-	intron-Distal	3.45829	5.18989	HepG2	PRPF4
chr1	205418434	205418532	-	intron-Distal	5.40677	25.10155	HepG2	DROSHA
chr1	205417221	205417251	-	intron-Distal	7.43715	40.75221	HepG2	DGCR8
chr1	205418294	205418368	-	intron-Distal	6.15132	16.93937	K562	DGCR8
chr1	205418600	205418647	-	intron-Distal	7.42334	35.18177	HepG2	DGCR8
chr1	205417794	205417860	-	intron-Distal	8.12370	63.61605	HepG2	DGCR8
chr1	205417789	205417846	-	intron-Distal	4.64397	15.38309	HepG2	DROSHA
chr1	205417507	205417552	-	intron-Distal	7.88008	165.60802	HepG2	DGCR8
chr1	205417320	205417329	-	intron-Distal	7.72586	105.30496	HepG2	DGCR8
chr1	205417720	205417736	-	intron-Distal	5.85752	13.11190	HepG2	DGCR8
chr1	205417511	205417664	-	intron-Distal	7.58849	57.79258	K562	DROSHA
chr1	205418657	205418779	-	intron-Distal	6.88204	46.99137	HepG2	DROSHA
chr1	205417266	205417357	-	intron-Distal	5.91135	13.37926	K562	DROSHA
chr1	205418797	205418854	-	intron-Distal	7.51141	44.09330	HepG2	DGCR8
chr1	205417171	205417219	-	intron-Distal	4.49906	14.26006	HepG2	DROSHA
chr1	205416783	205416860	-	intron-Distal	4.32404	6.00936	HepG2	XPO5
chr1	205418312	205418372	-	intron-Distal	5.02394	10.82831	HepG2	DROSHA
chr1	205418448	205418479	-	intron-Distal	6.71128	24.65588	HepG2	DGCR8
chr1	205417165	205417221	-	intron-Distal	8.13880	66.36676	HepG2	DGCR8
chr1	205418651	205418758	-	intron-Distal	5.21519	15.00318	K562	DROSHA
chr1	205417877	205417941	-	intron-Distal	7.53821	44.37817	HepG2	DGCR8
chr1	205418151	205418163	-	intron-Distal	5.36085	12.30783	HepG2	DGCR8
chr1	205417491	205417502	-	intron-Distal	5.41436	9.43880	K562	DGCR8
chr1	205416378	205416466	-	intron-Distal	3.62628	9.68409	HepG2	QKI
chr1	205416998	205417074	-	intron-Distal	5.95609	39.34925	HepG2	DGCR8
chr1	205419224	205419252	-	intron-Distal	5.02676	5.33511	HepG2	HNRNPK
chr1	205417449	205417507	-	intron-Distal	9.34474	143.46956	HepG2	DGCR8
chr1	205410148	205410240	-	intron-Distal	4.50090	5.14122	HepG2	PCBP2
chr1	205416568	205416633	-	intron-Distal	3.04574	3.23948	HepG2	HNRNPK
chr1	205417949	205418030	-	intron-Distal	6.36784	54.44415	HepG2	DGCR8
chr1	205417251	205417320	-	intron-Distal	7.40624	164.22581	HepG2	DGCR8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for LEMD1 is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for LEMD1 is not available on ENCORE database.
2 RBPs can affect the levels of LEMD1.

The Knockdown/knockout RNA-Seq assay for LEMD1 is not available on ENCORE database.

2 RBPs can affect the gene expression of LEMD1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
LEMD1	ENSG00000186007.5	6.68800	0.00000	99999.99990	2.15680	1.32140	HepG2	SMNDC1
LEMD1	ENSG00000186007.5	8.00900	0.00000	99999.99990	2.46070	1.79130	K562	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

LEMD1

General Information

Functions

Localization

Domains (AlphaFold: LEMD1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for LEMD1 is not avaliable on ENCORE database.

11 proteins are bound to LEMD1 RNA:

eCLIP assay for LEMD1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for LEMD1 is not available on ENCORE database.

2 RBPs can affect the gene expression of LEMD1 :

The Knockdown/knockout RNA-Seq assay for LEMD1 is not available on ENCORE database.

No RBPs affect the alternative splcing events of LEMD1 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for LEMD1 is not avaliable on ENCORE database.