EIF2D

General Information

Gene Name : EIF2D
Gene ID : ENSG00000143486.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EIF2D)

Not Available

Antibody Validation

Bethyl Labs: A303-006A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EIF2D	ENSG00000143486.15	68.07	74.06	71.06	ENCSR000AEF
HepG2	EIF2D	ENSG00000143486.15	42.34	43.87	43.11	ENCSR985KAT
K562	EIF2D	ENSG00000143486.15	80.40	86.31	83.36	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
EIF2D		A303-006A	1				BGHcLV39-53, Submitted, ENCORE2	BGKcLV38-45, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
EIF2D	K562	CRISPR			EIF2D-BGKcLV38-45,EIF2D-BGKcLV38-46	NT-BGKcLV38-1,NT-BGKcLV38-2	53.0,56.0	Submitting	ENCORE2
EIF2D	HepG2	CRISPR			EIF2D-BGHcLV39-53,EIF2D-BGHcLV39-54	NT-BGHcLV39-1,NT-BGHcLV39-2	89.4,94.1	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
EIF2D	Product_ID: A303-006A Lot_ID: 1 Source: Bethyl Labs Target Name: EIF2D-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EIF2D is not avaliable on ENCORE database.

Proteins bound to RNA

EIF2D RNA is bound by 13 proteins.

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eCLIP assay for EIF2D is not avaliable on ENCORE database.

13 proteins are bound to EIF2D RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	206773631	206773713	-	CDS,intron-Distal,intron-Proximal	3.98414	15.18333	K562	SF3B4
chr1	206784673	206784715	-	CDS,intron-Distal	4.05017	12.87748	K562	YBX3
chr1	206773564	206773625	-	CDS,intron-Distal,intron-Proximal	4.93262	11.82040	K562	AQR
chr1	206776246	206776320	-	CDS,intron-Distal,intron-Proximal	3.46642	10.90205	K562	PRPF8
chr1	206775798	206775869	-	CDS,intron-Distal,intron-Proximal	3.69750	10.38328	K562	SF3B4
chr1	206785641	206785698	-	5'-UTR,CDS,intron-Distal	3.13759	10.25312	K562	YBX3
chr1	206773515	206773608	-	intron-Distal,intron-Proximal	4.50806	9.23680	K562	EFTUD2
chr1	206775693	206775741	-	CDS,intron-Distal,intron-Proximal	4.08807	9.00050	K562	YBX3
chr1	206775580	206775684	-	intron-Distal,intron-Proximal	4.17206	8.79285	K562	AQR
chr1	206778709	206778724	-	intron-Distal,intron-Proximal	4.70636	8.52787	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 40 entries

eCLIP assay for EIF2D is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EIF2D is not available on ENCORE database.
101 RBPs can affect the levels of EIF2D.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EIF2D is not available on ENCORE database.

101 RBPs can affect the gene expression of EIF2D :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EIF2D	ENSG00000143486.11	514.23830	1587.09000	-1.62590	65.42720	63.29090	HepG2	SF3B4
EIF2D	ENSG00000143486.11	606.94230	2007.82780	-1.72600	56.76330	54.22760	K562	HNRNPC
EIF2D	ENSG00000143486.11	636.89370	1524.36120	-1.25910	42.39180	40.78840	HepG2	PTBP1
EIF2D	ENSG00000143486.11	427.92270	1452.55230	-1.76320	33.52750	31.72260	HepG2	DDX6
EIF2D	ENSG00000143486.11	440.36320	999.61240	-1.18270	32.70540	30.88550	HepG2	ZC3H8
EIF2D	ENSG00000143486.11	502.84660	1566.15980	-1.63900	30.96270	29.02930	HepG2	MATR3
EIF2D	ENSG00000143486.11	639.17000	1498.33760	-1.22910	28.57770	26.58590	HepG2	RBM25
EIF2D	ENSG00000143486.11	701.50510	1347.69200	-0.94200	26.00880	24.64040	HepG2	SRSF9
EIF2D	ENSG00000143486.11	729.65250	1424.83140	-0.96550	22.04510	20.86500	HepG2	RBM22
EIF2D	ENSG00000143486.11	953.52920	1656.56470	-0.79680	20.71370	19.67330	HepG2	SRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 115 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EIF2D is not available on ENCORE database.

14 RBPs can affect the splicing of EIF2D :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	EIF2D	ENSG00000143486.11	chr1	-	206772816	206772966	206772356	206772446	206773616	206773662	-0.22900	0.00000	0.00000	excluded	K562	EFTUD2
SE	EIF2D	ENSG00000143486.11	chr1	-	206778752	206778860	206773616	206773662	206781588	206781679	-0.10700	0.00000	0.00008	excluded	K562	HNRNPU
SE	EIF2D	ENSG00000143486.11	chr1	-	206773086	206773190	206772356	206772446	206773616	206773662	-0.26400	0.00000	0.00002	excluded	HepG2	HNRNPC
SE	EIF2D	ENSG00000143486.11	chr1	-	206774111	206774258	206773616	206773662	206775689	206775807	0.06300	0.00000	0.00000	included	K562	HNRNPC
SE	EIF2D	ENSG00000143486.11	chr1	-	206777962	206778083	206776436	206776558	206778752	206778860	0.48600	0.00000	0.00000	included	K562	HNRNPC
SE	EIF2D	ENSG00000143486.11	chr1	-	206773086	206773190	206772816	206772966	206773616	206773662	-0.25000	0.00000	0.00000	excluded	K562	HNRNPC
SE	EIF2D	ENSG00000143486.11	chr1	-	206775689	206775807	206773616	206773662	206778752	206778860	-0.16300	0.00000	0.00000	excluded	K562	HNRNPC
SE	EIF2D	ENSG00000143486.11	chr1	-	206772816	206772966	206772356	206772446	206773616	206773662	-0.17100	0.00001	0.00063	excluded	K562	PRPF8
SE	EIF2D	ENSG00000143486.11	chr1	-	206773086	206773190	206772356	206772446	206773616	206773662	-0.15900	0.00001	0.00065	excluded	K562	TARDBP
SE	EIF2D	ENSG00000143486.11	chr1	-	206777962	206778083	206776436	206776558	206778752	206778860	0.17300	0.00001	0.00070	included	HepG2	HNRNPC

Showing 1 to 10 of 29 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EIF2D

General Information

Functions

Localization

Domains (AlphaFold: EIF2D)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EIF2D is not avaliable on ENCORE database.

13 proteins are bound to EIF2D RNA:

eCLIP assay for EIF2D is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EIF2D is not available on ENCORE database.

101 RBPs can affect the gene expression of EIF2D :

The Knockdown/knockout RNA-Seq assay for EIF2D is not available on ENCORE database.

14 RBPs can affect the splicing of EIF2D :

The Knockdown/knockout RNA-Seq assay for EIF2D is not avaliable on ENCORE database.