CDC5L

General Information

Gene Name : CDC5L
Gene ID : ENSG00000096401.7
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CDC5L)

Not Available

Antibody Validation

Bethyl Labs: A301-681A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CDC5L	ENSG00000096401.7	18.24	16.22	17.23	ENCSR000AEF
HepG2	CDC5L	ENSG00000096401.7	13.67	25.61	19.64	ENCSR985KAT
K562	CDC5L	ENSG00000096401.7	21.26	22.81	22.04	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CDC5L-BGKcLV28-K562	ENCSR544ZMX	CDC5L	K562	Released		ENCSR220DTX	CRISPR	KD% = 55.5,59.1

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CDC5L	ENCAB386CPV	A301-681A	1			Released, ENCODE4	BGHcLV49-15, Experimented, ENCORE2	BGKcLV28-11, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CDC5L	K562	CRISPR	ENCSR544ZMX	ENCSR220DTX	CDC5L-BGKcLV28-11,CDC5L-BGKcLV28-12	NT-BGKcLV28-1,NT-BGKcLV28-2	55.5,59.1	Released	ENCODE4
CDC5L	HepG2	CRISPR			BGHcLV27-63,BGHcLV27-64	BGHcLV27-1,BGHcLV27-2	no clear band,	NotSatisfied	ENCODE4
CDC5L	HepG2	CRISPR			BGHcLV49-15,BGHcLV49-16	BGHcLV49-1,BGHcLV49-2	61.8,49.8	Sequenced	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CDC5L	Product_ID: A301-681A Lot_ID: 1 Source: Bethyl Labs Target Name: CDC5L-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CDC5L is not avaliable on ENCORE database.

Proteins bound to RNA

CDC5L RNA is bound by 23 proteins.

CanvasJS.com

eCLIP assay for CDC5L is not avaliable on ENCORE database.

23 proteins are bound to CDC5L RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	44360457	44360527	+	CDS	5.12426	22.84851	K562	UCHL5
chr6	44360403	44360457	+	CDS,intron-Proximal	5.07510	21.38144	K562	UCHL5
chr6	44360405	44360478	+	CDS	4.90838	19.67376	K562	ZNF622
chr6	44358003	44358095	+	CDS,intron-Proximal	4.24643	17.56831	K562	ZNF622
chr6	44358037	44358102	+	CDS	4.99016	14.74774	K562	UCHL5
chr6	44374092	44374200	+	CDS	3.46138	14.65559	K562	UCHL5
chr6	44358023	44358103	+	CDS	4.65634	13.32408	HepG2	BCLAF1
chr6	44397535	44397608	+	CDS	4.41272	12.88094	HepG2	BCLAF1
chr6	44413455	44413505	+	CDS	4.93203	12.55461	K562	UCHL5
chr6	44394313	44394439	+	CDS	4.19886	12.52201	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 118 entries

eCLIP assay for CDC5L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CDC5L is not available on ENCORE database.
77 RBPs can affect the levels of CDC5L.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CDC5L is not available on ENCORE database.

77 RBPs can affect the gene expression of CDC5L :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDC5L	ENSG00000096401.7	3089.70380	1818.60680	0.76450	27.10730	25.96130	HepG2	SRSF1
CDC5L	ENSG00000096401.7	1290.73860	2256.10490	-0.80560	24.06940	22.11800	HepG2	EIF4G1
CDC5L	ENSG00000096401.7	1019.05600	1636.78950	-0.68360	16.30470	15.09080	HepG2	TRIM56
CDC5L	ENSG00000096401.7	1450.47350	2106.89410	-0.53860	14.82540	13.80830	HepG2	ZNF622
CDC5L	ENSG00000096401.7	3595.34030	2227.41750	0.69070	15.02590	13.13110	K562	U2AF2
CDC5L	ENSG00000096401.7	1012.68180	1483.36090	-0.55070	12.20640	10.93990	HepG2	DNAJC2
CDC5L	ENSG00000096401.7	2965.11240	1750.65370	0.76010	11.97250	10.63690	HepG2	U2AF1
CDC5L	ENSG00000096401.7	1046.88730	1486.83610	-0.50610	9.69890	8.60630	HepG2	SAFB2
CDC5L	ENSG00000096401.7	1403.73460	2164.70980	-0.62490	9.48450	8.47150	HepG2	PUF60
CDC5L	ENSG00000096401.7	1315.54920	2068.03820	-0.65260	9.05020	8.04580	HepG2	BOP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 87 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CDC5L is not available on ENCORE database.

7 RBPs can affect the splicing of CDC5L :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CDC5L	ENSG00000096401.7	chr6	+	44397449	44397647			44394267	44394461	44413391	44413604	-0.05800	0.00000	0.00007	excluded	K562	AQR
SE	CDC5L	ENSG00000096401.7	chr6	+	44393839	44393920			44392155	44392320	44394218	44394461	-0.12400	0.00000	0.00001	excluded	K562	U2AF1
A3SS	CDC5L	ENSG00000096401.7	chr6	+	44392136	44392320			44392155	44392320	44390383	44390546	0.12400	0.00000	0.00000	longer	K562	AQR
MXE	CDC5L	ENSG00000096401.7	chr6	+	44394218	44394461	44397449	44397647	44392155	44392320	44413391	44413604	0.06600	0.00000	0.00001	1included	K562	U2AF1
MXE	CDC5L	ENSG00000096401.7	chr6	+	44394218	44394461	44397449	44397647	44392155	44392320	44413391	44413604	0.10300	0.00000	0.00000	1included	K562	AQR
MXE	CDC5L	ENSG00000096401.7	chr6	+	44394218	44394461	44397449	44397647	44392155	44392320	44413391	44413604	0.05900	0.00000	0.00010	1included	K562	SF3B4
SE	CDC5L	ENSG00000096401.7	chr6	+	44393839	44393920			44392155	44392320	44394218	44394461	-0.10600	0.00001	0.00023	excluded	K562	SF3B4
SE	CDC5L	ENSG00000096401.7	chr6	+	44395029	44395110			44394218	44394461	44397449	44397533	0.06200	0.00001	0.00111	included	K562	PRPF8
MXE	CDC5L	ENSG00000096401.7	chr6	+	44394218	44394461	44397449	44397647	44392155	44392320	44413391	44413604	0.05900	0.00055	0.01486	1included	K562	PRPF8
SE	CDC5L	ENSG00000096401.7	chr6	+	44393839	44393920			44392155	44392320	44397449	44397647	-0.05300	0.00133	0.02159	excluded	K562	PUS1

Showing 1 to 10 of 14 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CDC5L

General Information

Functions

Localization

Domains (AlphaFold: CDC5L)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CDC5L is not avaliable on ENCORE database.

23 proteins are bound to CDC5L RNA:

eCLIP assay for CDC5L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CDC5L is not available on ENCORE database.

77 RBPs can affect the gene expression of CDC5L :

The Knockdown/knockout RNA-Seq assay for CDC5L is not available on ENCORE database.

7 RBPs can affect the splicing of CDC5L :

The Knockdown/knockout RNA-Seq assay for CDC5L is not avaliable on ENCORE database.