SECISBP2

General Information

Gene Name       : SECISBP2
Gene ID             : ENSG00000187742.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SECISBP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SECISBP2ENSG00000187742.1442.3432.8837.61ENCSR000AEF
HepG2SECISBP2ENSG00000187742.1418.8626.3122.59ENCSR985KAT
K562SECISBP2ENSG00000187742.1422.2224.2023.21ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq BGKcLV33-37,BGKcLV33-38SECISBP2K562Released   CRISPRKD% = no band on the position,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
SECISBP2K562CRISPRBGKcLV33-37,BGKcLV33-38BGKcLV33-1,BGKcLV33-2no band on the position,ReleasedENCODE4
SECISBP2K562CRISPRBGKcLV33-43,BGKcLV33-44BGKcLV33-1,BGKcLV33-20.0,0.0NotSatisfiedENCODE4
SECISBP2K562CRISPRBGKcLV35-65,BGKcLV35-66BGKcLV35-1,BGKcLV35-28.0,0.0NotSatisfiedENCORE2
SECISBP2HepG2CRISPRBGHcLV31-39,BGHcLV31-40BGHcLV31-1,BGHcLV31-2NO CLEAR BAND,NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SECISBP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SECISBP2 RNA is bound by 19 proteins.  







eCLIP assay for SECISBP2 is not avaliable on ENCORE database.





19 proteins are bound to SECISBP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr99197402091974200+3'-UTR4.582485.03717HepG2PABPN1
chr99197366891973777+3'-UTR,CDS3.269644.00731K562UCHL5
chr99197382291973872+3'-UTR3.372826.19339HepG2BCLAF1
chr99197375091973873+3'-UTR3.308123.93901K562KHSRP
chr99194766191947714+5'-UTR,intron-Distal4.239223.73609HepG2KHSRP
chr99193344091933520+5'-UTR,CDS3.382885.08370HepG2DDX3X
chr99193460291934678+5'-UTR,CDS3.831783.01428K562UCHL5
chr99194764991947779+5'-UTR,intron-Distal,intron-Proximal3.329866.67026K562KHSRP
chr99194774191947820+5'-UTR,intron-Proximal3.457274.54121HepG2KHSRP
chr99193458391934696+5'-UTR,CDS3.220966.18332HepG2GRWD1
chr99194777791947853+5'-UTR,CDS,intron-Proximal4.126945.16342K562SF3B4
chr99193352391933571+5'-UTR,CDS,intron-Proximal3.654203.67894HepG2AQR
chr99196299391963036+CDS,intron-Proximal4.312383.78281HepG2FXR2
chr99195626891956364+CDS4.401033.59236HepG2AQR
chr99196304491963105+CDS4.715047.17283HepG2GRWD1
chr99196311591963129+CDS3.826265.35703HepG2BCLAF1
chr99194357291943590+CDS,intron-Proximal3.821417.65975HepG2BCLAF1
chr99196557391965729+CDS4.020294.25199K562GRWD1
chr99195636891956396+CDS,intron-Proximal3.533783.27569HepG2BCLAF1
chr99196188491961959+CDS3.442173.95301K562ZNF622
chr99195337891953498+CDS,intron-Proximal3.207423.84771K562ZNF622
chr99197235191972481+CDS,intron-Proximal3.306905.80517HepG2GRWD1
chr99196179591961811+CDS,intron-Proximal3.599413.27569HepG2BCLAF1
chr99194052691940592+CDS,intron-Proximal4.775884.90367K562ZNF622
chr99194081091940841+CDS,intron-Proximal5.402278.75808HepG2BCLAF1
chr99194055491940593+CDS,intron-Proximal3.508145.76104HepG2BCLAF1
chr99197240991972506+CDS,intron-Proximal3.554934.41267HepG2PPIG
chr99196299791963044+CDS3.957764.04622HepG2GRWD1
chr99194364191943706+CDS3.904328.66838HepG2BCLAF1
chr99197238291972482+CDS,intron-Proximal4.8069215.55279HepG2BCLAF1
chr99196559591965766+CDS3.4651413.63814HepG2BCLAF1
chr99197231091972354+CDS,intron-Proximal3.040373.48131HepG2U2AF2
chr99196310591963130+CDS,intron-Proximal3.059073.63043HepG2GRWD1
chr99196469091964705+CDS,intron-Proximal3.065883.94979HepG2BCLAF1
chr99194081191940890+CDS,intron-Proximal3.522403.95301K562ZNF622
chr99197291391972927+CDS,intron-Proximal3.359823.57857HepG2BCLAF1
chr99197364991973713+CDS3.515934.41267HepG2PPIG
chr99194084191940898+CDS5.1826214.25738HepG2BCLAF1
chr99196305591963129+CDS3.018173.84771K562ZNF622
chr99196299391963094+CDS,intron-Proximal3.042515.51984K562UCHL5
chr99196304791963115+CDS6.2483517.22331HepG2BCLAF1
chr99196300091963047+CDS5.198867.39496HepG2BCLAF1
chr99194378091943837+CDS,intron-Proximal5.055275.68502HepG2PRPF8
chr99195627491956380+CDS3.679985.53307K562ZNF622
chr99194956091949632+CDS3.513064.22563K562UCHL5
chr99194963091949645+CDS4.377103.71570HepG2BCLAF1
chr99197364691973729+CDS3.218373.79741HepG2GRWD1
chr99197365791973720+CDS3.366355.40132HepG2BCLAF1
chr99194091091940954+CDS,intron-Proximal3.358256.09950HepG2BCLAF1
chr99197300191973015+CDS4.067343.06595HepG2BCLAF1
chr99195626991956357+CDS3.657477.93794HepG2BCLAF1
chr99195345691953495+CDS3.665304.09885HepG2BCLAF1
chr99197364091973706+CDS4.333623.77023K562ZNF622
chr99196299991963051+CDS3.313733.59112HepG2PPIG
chr99196810491968173+intron-Distal3.033223.72889HepG2SUGP2
chr99194625991946277+intron-Distal5.003128.11176K562TIA1
chr99194385191943981+intron-Distal,intron-Proximal4.551785.44709K562KHSRP
chr99194389391943960+intron-Distal,intron-Proximal3.442173.54718K562PRPF8
chr99194604191946188+intron-Distal4.377825.44709K562KHSRP
chr99194508491945169+intron-Distal3.556884.21358HepG2U2AF2
chr99193588091935987+intron-Distal4.7272413.69723K562KHSRP
chr99194000591940066+intron-Distal4.426895.02084HepG2HNRNPM
chr99193825391938431+intron-Distal3.547776.07628HepG2EXOSC5
chr99196625591966325+intron-Distal4.167983.89080K562EXOSC5
chr99196054091960609+intron-Distal4.659235.16513HepG2HNRNPM
chr99193712191937216+intron-Distal3.143943.51696K562KHSRP
chr99193561891935706+intron-Distal4.2657015.49278HepG2U2AF2
chr99196786891967909+intron-Distal5.013467.15660HepG2HNRNPM
chr99194627791946309+intron-Distal5.066968.81987K562TIA1
chr99193869691938750+intron-Distal3.682286.62503K562KHSRP
chr99194614391946228+intron-Distal4.823896.15877HepG2U2AF2
chr99196056691960660+intron-Distal3.960943.78162K562HNRNPM
chr99196741991967441+intron-Distal3.885023.39864HepG2SUGP2
chr99193865091938696+intron-Distal4.212744.72162K562KHSRP
chr99196786391967928+intron-Distal4.167504.51377K562HNRNPM
chr99197213991972233+intron-Distal,intron-Proximal3.336196.36450HepG2U2AF2
chr99196848291968519+intron-Distal3.498924.61500HepG2HNRNPM
chr99193653091936577+intron-Distal4.891513.18269HepG2XPO5
chr99196631291966382+intron-Distal4.301126.98528HepG2HNRNPM
chr99193561991935690+intron-Distal4.065453.65740K562U2AF2
chr99193582091935879+intron-Distal4.619495.60990HepG2KHSRP
chr99196660491966654+intron-Distal3.045983.10883HepG2SUGP2
chr99193587991935954+intron-Distal3.706235.82781HepG2KHSRP
chr99196797791968014+intron-Distal3.072964.53269HepG2HNRNPM
chr99193475891934872+intron-Distal,intron-Proximal8.1232147.51028HepG2XPO5
chr99194437891944435+intron-Distal3.124323.89901HepG2HNRNPC
chr99196818991968244+intron-Distal3.919646.29995HepG2HNRNPM
chr99196044991960540+intron-Distal4.949097.23521HepG2HNRNPM
chr99196603791966079+intron-Distal4.419643.60235HepG2HNRNPM
chr99193584691935880+intron-Distal3.6163411.04913K562KHSRP
chr99193579891935846+intron-Distal4.0384013.08623K562KHSRP
chr99196625591966326+intron-Distal4.877867.65425HepG2SUGP2
chr99194738491947454+intron-Distal4.517478.98750HepG2U2AF2
chr99196172191961786+intron-Proximal4.454035.31973HepG2SF3B4
chr99193352791933572+intron-Proximal4.123635.63763K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SECISBP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SECISBP2 is not available on ENCORE database.

  • 60 RBPs can affect the levels of SECISBP2.  








The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.





60 RBPs can affect the gene expression of SECISBP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SECISBP2ENSG00000187742.101968.829101601.405400.297903.894203.10500HepG2AUH
SECISBP2ENSG00000187742.101535.71240897.082800.7755010.384309.13640HepG2CPSF6
SECISBP2ENSG00000187742.10718.705701450.77420-1.0134014.2860012.97660HepG2DDX3X
SECISBP2ENSG00000187742.101637.028201018.708600.684203.917002.76490HepG2DDX59
SECISBP2ENSG00000187742.10626.260601246.20870-0.9927011.7474010.58140HepG2DDX6
SECISBP2ENSG00000187742.10687.43060829.22270-0.270502.592201.95710HepG2DNAJC2
SECISBP2ENSG00000187742.101488.354801198.046800.312901.962501.45340HepG2EIF2S1
SECISBP2ENSG00000187742.101744.311401324.000000.397702.758202.11990HepG2EIF4A3
SECISBP2ENSG00000187742.101702.404001289.066400.401102.222301.60220HepG2EIF4B
SECISBP2ENSG00000187742.101682.229701324.559800.344804.390203.37870HepG2EIF4G1
SECISBP2ENSG00000187742.102338.092501838.621400.346605.571204.76740HepG2ETF1
SECISBP2ENSG00000187742.10900.058001335.80760-0.569605.159804.23530HepG2FXR1
SECISBP2ENSG00000187742.101517.52890970.422100.644907.083106.12920HepG2HNRNPLL
SECISBP2ENSG00000187742.101074.348001336.27370-0.314801.922401.37010HepG2MAGOH
SECISBP2ENSG00000187742.10744.46710950.92530-0.353102.738101.52660HepG2NAA15
SECISBP2ENSG00000187742.10986.189401375.42140-0.479903.737803.00620HepG2NCBP2
SECISBP2ENSG00000187742.10840.663301188.80920-0.499902.346001.54090HepG2PABPC1
SECISBP2ENSG00000187742.101421.108001224.858200.214302.155501.60840HepG2PCBP1
SECISBP2ENSG00000187742.10999.14170832.454800.263202.131801.47760HepG2PPIL4
SECISBP2ENSG00000187742.102065.420101349.732000.6137011.3915010.25180HepG2QKI
SECISBP2ENSG00000187742.101654.690901306.965700.340202.634101.96510HepG2RPLP0
SECISBP2ENSG00000187742.101477.206501015.688800.540303.244102.22210HepG2RPS10
SECISBP2ENSG00000187742.10898.26530638.503300.492303.358702.50320HepG2RRP9
SECISBP2ENSG00000187742.101095.75870831.178700.398605.332304.49090HepG2SAFB2
SECISBP2ENSG00000187742.101008.778501434.32970-0.507803.471402.71320HepG2SF3A3
SECISBP2ENSG00000187742.101264.85170960.501500.397003.261902.50140HepG2SF3B1
SECISBP2ENSG00000187742.101455.932301068.735200.445902.328401.61450HepG2SNRNP70
SECISBP2ENSG00000187742.102788.108301735.703200.6837021.9664020.90570HepG2SRFBP1
SECISBP2ENSG00000187742.10966.995401354.40910-0.486104.098403.55060HepG2SRSF1
SECISBP2ENSG00000187742.101363.021601101.934400.306703.922803.28880HepG2SRSF9
SECISBP2ENSG00000187742.101425.457401118.597600.349603.422502.49720HepG2TIA1
SECISBP2ENSG00000187742.101087.03180906.972200.261201.942201.50770HepG2TIAL1
SECISBP2ENSG00000187742.10889.575201196.96380-0.428203.447402.75160HepG2U2AF1
SECISBP2ENSG00000187742.10916.152801228.09710-0.422805.773804.96080HepG2UTP3
SECISBP2ENSG00000187742.101247.80920998.126200.322003.972503.19170HepG2ZC3H8
SECISBP2ENSG00000187742.101479.794301839.50290-0.313904.133303.46440K562AGGF1
SECISBP2ENSG00000187742.101402.775501914.07140-0.448404.775503.90990K562AKAP8L
SECISBP2ENSG00000187742.10386.84270609.95140-0.656905.478303.87390K562CCAR1
SECISBP2ENSG00000187742.101605.089002198.35490-0.453806.204204.40850K562CCDC124
SECISBP2ENSG00000187742.101246.969701540.33630-0.304803.276602.06530K562CPEB4
SECISBP2ENSG00000187742.10720.42860942.00500-0.386903.853902.23170K562DDX6
SECISBP2ENSG00000187742.10488.57840806.43290-0.723007.253205.71360K562EFTUD2
SECISBP2ENSG00000187742.10601.10380863.39270-0.522403.577502.38450K562EIF3D
SECISBP2ENSG00000187742.10708.45320970.69720-0.454303.946902.96860K562EIF4A3
SECISBP2ENSG00000187742.10601.16230932.21030-0.632906.285304.97840K562FMR1
SECISBP2ENSG00000187742.10655.885501009.48230-0.622109.086808.06410K562FXR1
SECISBP2ENSG00000187742.10587.81170948.79330-0.690708.174707.19870K562HNRNPC
SECISBP2ENSG00000187742.101018.917101257.21280-0.303202.899001.98410K562HNRNPU
SECISBP2ENSG00000187742.101590.939702031.35990-0.352603.582502.62980K562KIF1C
SECISBP2ENSG00000187742.10726.382101113.25580-0.616007.537906.12410K562MAGOH
SECISBP2ENSG00000187742.101164.688301595.04650-0.453702.905701.99850K562NAA15
SECISBP2ENSG00000187742.10587.42120794.72770-0.436102.886801.55880K562NONO
SECISBP2ENSG00000187742.101180.305201378.09610-0.223502.563801.84160K562NSUN2
SECISBP2ENSG00000187742.10775.236001129.87450-0.543504.464603.41010K562PCBP3
SECISBP2ENSG00000187742.10575.11940866.67150-0.591606.583105.35770K562POLR2G
SECISBP2ENSG00000187742.10551.82760784.75340-0.508003.810002.93130K562PRPF8
SECISBP2ENSG00000187742.101504.751202288.72350-0.605008.082406.68350K562PUF60
SECISBP2ENSG00000187742.101854.877602385.24670-0.362805.015203.70760K562PUM2
SECISBP2ENSG00000187742.101514.395601898.33940-0.326002.413301.89830K562PUS1
SECISBP2ENSG00000187742.101552.713001849.55810-0.252402.406901.84700K562RBM15
SECISBP2ENSG00000187742.10725.431701037.14540-0.515704.930803.76870K562RBM22
SECISBP2ENSG00000187742.10737.18210965.44890-0.389203.397802.44770K562SF3B4
SECISBP2ENSG00000187742.101083.016201393.28240-0.363405.155103.92440K562SRPK2
SECISBP2ENSG00000187742.10679.343101060.31760-0.642307.931806.74140K562SRSF1
SECISBP2ENSG00000187742.10768.680501073.12200-0.481404.094203.22790K562TARDBP
SECISBP2ENSG00000187742.101010.310401461.22970-0.532409.867108.61620K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.





12 RBPs can affect the splicing of SECISBP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESECISBP2ENSG00000187742.10chr9+919403419194059191934566919347129194081191940953-0.126000.003800.07792excludedHepG2HNRNPK
SESECISBP2ENSG00000187742.10chr9+9194893991949070919478319194790191949436919496450.320000.001610.03752includedHepG2SRSF1
SESECISBP2ENSG00000187742.10chr9+919547789195486891953372919534959195626191956394-0.131000.000020.00224excludedHepG2SF3B4
SESECISBP2ENSG00000187742.10chr9+919345669193471291933420919335279194034191940591-0.083000.003150.07945excludedK562UTP18
A3SSSECISBP2ENSG00000187742.10chr9+919403419194059191940462919405919193456691934712-0.489000.000070.00895shorterHepG2SRSF1
A3SSSECISBP2ENSG00000187742.10chr9+9194943691949645919495509194964591947822919479010.353000.000260.00861longerHepG2U2AF2
A3SSSECISBP2ENSG00000187742.10chr9+919403419194059191940462919405919193460791934712-0.247000.001350.03397shorterHepG2U2AF2
A3SSSECISBP2ENSG00000187742.10chr9+9195334491953495919533729195349591949404919496450.168000.000000.00000longerK562AQR
A3SSSECISBP2ENSG00000187742.10chr9+9194943691949645919495509194964591947822919479010.346000.001010.04622longerK562U2AF1
A3SSSECISBP2ENSG00000187742.10chr9+919403419194059191940462919405919193456691934712-0.381000.000110.00720shorterK562U2AF1
A3SSSECISBP2ENSG00000187742.10chr9+919403419194059191940462919405919193456691934712-0.382000.000080.00893shorterHepG2SF3B4
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194034191940591919334209193352791940811919409530.322000.000000.000011includedHepG2MATR3
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194034191940591919334209193352791940811919409530.217000.000420.049931includedHepG2KHSRP
MXESECISBP2ENSG00000187742.10chr9+9193456691934712919403419194059191933420919335279194081191940953-0.148000.004800.075792includedHepG2SRSF1
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194034191940591919334209193352791940811919409530.215000.000170.016671includedHepG2IGF2BP3
MXESECISBP2ENSG00000187742.10chr9+9193456691934712919403419194059191933420919335279194081191940953-0.297000.000000.000012includedK562AQR
MXESECISBP2ENSG00000187742.10chr9+9193456691934712919403419194059191933420919335279194081191940953-0.207000.000390.028392includedK562UTP18
MXESECISBP2ENSG00000187742.10chr9+91934575919347129194034191940591919334209193352791940811919409530.108000.001820.042421includedHepG2HNRNPK
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194034191940591919334209193352791940811919409530.240000.000160.012581includedHepG2DDX3X
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194034191940591919334209193352791940811919409530.192000.010060.097021includedK562HNRNPUL1
MXESECISBP2ENSG00000187742.10chr9+91934566919347129194046291940591919334339193352791940811919409530.195000.010010.096851includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SECISBP2 is not avaliable on ENCORE database.