MCOLN1

General Information

Gene Name       : MCOLN1
Gene ID             : ENSG00000090674.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MCOLN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MCOLN1ENSG00000090674.151.202.521.86ENCSR000AEF
HepG2MCOLN1ENSG00000090674.158.022.425.22ENCSR985KAT
K562MCOLN1ENSG00000090674.156.444.785.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MCOLN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MCOLN1 RNA is bound by 1 proteins.  







eCLIP assay for MCOLN1 is not avaliable on ENCORE database.





1 proteins are bound to MCOLN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1975917977591856+CDS,intron-Proximal5.027027.92973HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MCOLN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MCOLN1 is not available on ENCORE database.

  • 62 RBPs can affect the levels of MCOLN1.  








The Knockdown/knockout RNA-Seq assay for MCOLN1 is not available on ENCORE database.





62 RBPs can affect the gene expression of MCOLN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MCOLN1ENSG00000090674.11214.4628093.899901.191404.942904.25890HepG2AKAP1
MCOLN1ENSG00000090674.11193.25270100.085500.949205.786604.71450HepG2AKAP8L
MCOLN1ENSG00000090674.11234.28520106.554701.136607.347006.42740HepG2BOP1
MCOLN1ENSG00000090674.11132.5935035.493301.901308.267106.96160HepG2CNOT7
MCOLN1ENSG00000090674.11207.87020104.217900.996006.782505.69730HepG2DAZAP1
MCOLN1ENSG00000090674.11280.6022089.916501.6418011.8458010.63530HepG2DDX3X
MCOLN1ENSG00000090674.11117.0601067.503600.794102.141901.33760HepG2EIF3D
MCOLN1ENSG00000090674.11227.66730147.388900.627202.241601.54470HepG2FIP1L1
MCOLN1ENSG00000090674.11147.0480082.864800.827402.541701.87730HepG2FXR1
MCOLN1ENSG00000090674.11131.9329076.810600.780302.190901.59590HepG2G3BP1
MCOLN1ENSG00000090674.11130.5670067.190500.958403.325402.20320HepG2GNB2L1
MCOLN1ENSG00000090674.1171.1271032.862601.113902.681501.58680HepG2GRSF1
MCOLN1ENSG00000090674.1178.3191029.336901.416504.416202.63750HepG2HNRNPAB
MCOLN1ENSG00000090674.11136.2973077.914600.806702.368401.71940HepG2HNRNPK
MCOLN1ENSG00000090674.11125.5358071.964500.802603.209602.56030HepG2HNRNPU
MCOLN1ENSG00000090674.11215.9051078.055401.467708.687207.56250HepG2IGF2BP2
MCOLN1ENSG00000090674.11114.7774073.510100.642702.177001.51770HepG2ILF2
MCOLN1ENSG00000090674.11253.72200137.631900.882304.079003.06620HepG2LARP4
MCOLN1ENSG00000090674.11174.3990082.894201.072904.785303.92970HepG2MAGOH
MCOLN1ENSG00000090674.11205.9523083.340001.305106.859305.89800HepG2MATR3
MCOLN1ENSG00000090674.11221.7007085.288401.378106.427805.47900HepG2NCBP2
MCOLN1ENSG00000090674.11108.1765069.564300.636902.042801.50860HepG2PCBP1
MCOLN1ENSG00000090674.11157.1364070.795801.150206.396805.63260HepG2PTBP1
MCOLN1ENSG00000090674.11174.49960104.711200.736703.684303.02050HepG2PUM1
MCOLN1ENSG00000090674.11164.52140104.637500.652801.946601.37780HepG2PUM2
MCOLN1ENSG00000090674.11202.26620101.464600.995206.605105.72430HepG2PUS1
MCOLN1ENSG00000090674.11297.00520148.965300.995407.102106.36240HepG2RBM22
MCOLN1ENSG00000090674.11133.9061078.779400.765202.240701.74380HepG2NELFE
MCOLN1ENSG00000090674.11134.4363065.698801.032904.093403.36040HepG2RPS19
MCOLN1ENSG00000090674.11126.1638073.224500.784802.252901.52560HepG2RPS2
MCOLN1ENSG00000090674.11130.9941074.752500.809202.433501.42870HepG2RPS5
MCOLN1ENSG00000090674.11344.41970149.448801.204408.980607.71180HepG2SF3A3
MCOLN1ENSG00000090674.11112.6992073.687000.612901.840601.34170HepG2SF3B4
MCOLN1ENSG00000090674.11121.6530074.744000.702602.497601.88200HepG2SMN1
MCOLN1ENSG00000090674.11106.14710168.24980-0.664502.683602.18690HepG2SRFBP1
MCOLN1ENSG00000090674.11175.3943097.391800.848604.330703.57860HepG2SRSF5
MCOLN1ENSG00000090674.1199.38360146.07880-0.555702.057301.59860HepG2SSB
MCOLN1ENSG00000090674.11222.84560110.766001.008406.801805.90200HepG2SUCLG1
MCOLN1ENSG00000090674.1130.5810069.16350-1.177403.074302.48810HepG2TAF15
MCOLN1ENSG00000090674.11139.7172071.976400.956802.628701.58520HepG2TBRG4
MCOLN1ENSG00000090674.11145.0522069.942601.052205.062204.42780HepG2TIAL1
MCOLN1ENSG00000090674.11133.0133070.551100.914704.131103.47010HepG2TRIM56
MCOLN1ENSG00000090674.11191.84790101.995200.911403.419302.48810HepG2UBE2L3
MCOLN1ENSG00000090674.11137.9299063.577601.117203.890402.99110HepG2UCHL5
MCOLN1ENSG00000090674.1169.9858031.953601.131002.912001.78100HepG2XPO5
MCOLN1ENSG00000090674.11302.54330212.242600.511302.684201.46220K562APOBEC3C
MCOLN1ENSG00000090674.11392.91170176.066801.158009.771708.77360K562AQR
MCOLN1ENSG00000090674.11177.5700099.713900.832402.816201.74170K562CNOT7
MCOLN1ENSG00000090674.11191.60360295.67100-0.625903.086602.05810K562CELF1
MCOLN1ENSG00000090674.1185.6880048.446000.822602.383901.41900K562DDX3X
MCOLN1ENSG00000090674.11253.91870190.555300.414101.899001.34050K562DDX47
MCOLN1ENSG00000090674.11158.7889093.163300.769202.812901.89150K562EFTUD2
MCOLN1ENSG00000090674.11107.8839050.618701.091604.246503.23060K562EIF4A3
MCOLN1ENSG00000090674.11195.9189052.642101.8959015.5198014.19600K562FXR1
MCOLN1ENSG00000090674.116.6848025.73480-1.944802.588201.90800K562G3BP2
MCOLN1ENSG00000090674.11156.1166095.608700.707302.574301.99540K562HNRNPC
MCOLN1ENSG00000090674.1186.7909049.690000.804502.385101.60210K562MAGOH
MCOLN1ENSG00000090674.11216.6586095.796201.177305.778203.97710K562PABPC1
MCOLN1ENSG00000090674.11216.18640137.773900.649903.144102.28670K562POLR2G
MCOLN1ENSG00000090674.11210.7597090.659301.217006.581105.42250K562PRPF8
MCOLN1ENSG00000090674.11202.4949048.281502.068208.965107.81340K562PTBP1
MCOLN1ENSG00000090674.11387.87370262.436800.563503.884402.92290K562PUF60
MCOLN1ENSG00000090674.11173.02090109.256200.663101.925201.45670K562PUS1
MCOLN1ENSG00000090674.11139.7869046.263101.595209.265607.58340K562RBM22
MCOLN1ENSG00000090674.1188.4183045.123000.970402.932501.49510K562RBM34
MCOLN1ENSG00000090674.11195.15760122.783300.668402.296501.31560K562SAFB
MCOLN1ENSG00000090674.11145.0663047.338801.615508.924307.66380K562SRSF1
MCOLN1ENSG00000090674.11152.7411047.895301.6730010.135308.64470K562TARDBP
MCOLN1ENSG00000090674.1193.5555046.204301.017702.080501.37800K562TIA1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MCOLN1 is not available on ENCORE database.





2 RBPs can affect the splicing of MCOLN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSMCOLN1ENSG00000090674.11chr19+7592749759293075927497592846759304375931160.110000.000470.00992longerK562AQR
RIMCOLN1ENSG00000090674.11chr19+7592405759284675924057592514759274975928460.338000.004180.06648includedHepG2PCBP2
RIMCOLN1ENSG00000090674.11chr19+7592405759284675924057592514759274975928460.473000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MCOLN1 is not avaliable on ENCORE database.