TREX2

General Information

Gene Name : TREX2
Gene ID : ENSG00000183479.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TREX2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TREX2	ENSG00000183479.12	0.04	0.06	0.05	ENCSR000AEF
HepG2	TREX2	ENSG00000183479.12	0.00	0.02	0.01	ENCSR985KAT
K562	TREX2	ENSG00000183479.12	0.15	0.07	0.11	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TREX2 is not avaliable on ENCORE database.

Proteins bound to RNA

TREX2 RNA is bound by 8 proteins.

eCLIP assay for TREX2 is not avaliable on ENCORE database.

8 proteins are bound to TREX2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chrX	152719811	152719902	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.42765	5.68502	HepG2	PRPF8
chrX	152722509	152722596	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.20412	4.15711	K562	AQR
chrX	152722591	152722662	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.56453	6.61971	K562	YBX3
chrX	152734671	152734718	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.83605	3.25175	K562	YBX3
chrX	152728099	152728184	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.19569	4.90235	K562	SF3B4
chrX	152728090	152728180	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.16468	3.96990	K562	BUD13
chrX	152720973	152721000	-	intron-Distal,intron-Proximal	4.56086	7.92018	K562	AQR
chrX	152731192	152731288	-	intron-Distal	4.25216	3.53896	K562	NONO
chrX	152716637	152716671	-	intron-Distal	6.09627	7.94676	HepG2	SF3A3
chrX	152716640	152716684	-	intron-Distal	5.21323	8.63731	HepG2	SF3B4
chrX	152716634	152716673	-	intron-Distal	4.73471	5.86588	K562	SMNDC1
chrX	152720956	152720973	-	intron-Distal,intron-Proximal	4.61860	8.69247	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for TREX2 is not avaliable on ENCORE database.

Summary
AS Affected by

Diffrential Expression

The Knockdown/knockout assay for TREX2 is not available on ENCORE database.
No RBPs affect the gene expression of TREX2 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for TREX2 is not available on ENCORE database.

No RBPs affect the gene expression of TREX2 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for TREX2 is not available on ENCORE database.

9 RBPs can affect the splicing of TREX2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	0.28800	0.00004	0.00137	included	K562	SRSF1
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	-0.25500	0.00000	0.00002	excluded	K562	AQR
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	0.53600	0.00029	0.00817	included	K562	U2AF1
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	0.39000	0.00010	0.00389	included	HepG2	SRSF1
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	0.33000	0.00139	0.05983	included	HepG2	SF3B4
SE	TREX2	ENSG00000183479.8	chrX	-	152730445	152730513			152728067	152728129	152734603	152734719	-0.06300	0.00141	0.04880	excluded	K562	HNRNPU
SE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511			152719851	152719966	152720999	152721224	0.29400	0.00109	0.04796	included	K562	HNRNPK
SE	TREX2	ENSG00000183479.8	chrX	-	152730445	152730513			152728067	152728129	152734603	152734719	-0.10600	0.00208	0.03508	excluded	K562	HNRNPC
A3SS	TREX2	ENSG00000183479.8	chrX	-	152721950	152722109			152721950	152722082	152722594	152722686	-0.27400	0.00021	0.00720	shorter	HepG2	U2AF2
MXE	TREX2	ENSG00000183479.8	chrX	-	152720334	152720511	152720999	152721224	152719851	152719966	152721722	152721822	-0.13200	0.00012	0.01776	2included	K562	HNRNPL

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TREX2

General Information

Functions

Localization

Domains (AlphaFold: TREX2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TREX2 is not avaliable on ENCORE database.

8 proteins are bound to TREX2 RNA:

eCLIP assay for TREX2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TREX2 is not available on ENCORE database.

No RBPs affect the gene expression of TREX2 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for TREX2 is not available on ENCORE database.

9 RBPs can affect the splicing of TREX2 :

The Knockdown/knockout RNA-Seq assay for TREX2 is not avaliable on ENCORE database.