CLTC

General Information

Gene Name : CLTC
Gene ID : ENSG00000141367.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CLTC)

Not Available

Antibody Validation

Bethyl Labs: A304-743A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CLTC	ENSG00000141367.11	69.54	71.54	70.54	ENCSR000AEF
HepG2	CLTC	ENSG00000141367.11	105.37	135.63	120.50	ENCSR985KAT
K562	CLTC	ENSG00000141367.11	102.53	116.75	109.64	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CLTC-BGKcLV28-K562	ENCSR899RVY	CLTC	K562	Released		ENCSR220DTX	CRISPR	KD% = 54.8,60.216034
knockdown followed by RNA-seq	CLTC-BGHcLV29-HepG2	ENCSR576ASZ	CLTC	HepG2	Released		ENCSR462MFN	CRISPR	KD% = 85.1,88.2

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CLTC	ENCAB019OFH	A304-743A	1			Released, ENCODE4	BGHcLV29-23, Released, ENCODE4	BGKcLV28-23, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
CLTC	K562	CRISPR	ENCSR899RVY	ENCSR220DTX	CLTC-BGKcLV28-23,CLTC-BGKcLV28-24	NT-BGKcLV28-1,NT-BGKcLV28-2	54.8,60.216034	Released	ENCODE4
CLTC	HepG2	CRISPR	ENCSR576ASZ	ENCSR462MFN	CLTC-BGHcLV29-23,CLTC-BGHcLV29-24	NT-BGHcLV29-1,NT-BGHcLV29-2	85.1,88.2	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CLTC	Product_ID: A304-743A Lot_ID: 1 Source: Bethyl Labs Target Name: CLTC-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CLTC is not avaliable on ENCORE database.

Proteins bound to RNA

CLTC RNA is bound by 60 proteins.

CanvasJS.com

eCLIP assay for CLTC is not avaliable on ENCORE database.

60 proteins are bound to CLTC RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	57771958	57772032	+	3'-UTR	6.68478	400.00000	HepG2	SUB1
chr17	57697454	57697458	+	5'-UTR	5.61032	400.00000	K562	FXR2
chr17	57697435	57697454	+	5'-UTR	5.53918	400.00000	K562	FXR2
chr17	57697426	57697435	+	5'-UTR	5.21158	85.58848	K562	FXR2
chr17	57697422	57697426	+	5'-UTR	4.82005	78.89918	K562	FXR2
chr17	57771853	57771946	+	3'-UTR	7.27736	71.06334	HepG2	SUB1
chr17	57737885	57737925	+	3'-UTR,CDS,intron-Distal	5.73637	58.14196	K562	LIN28B
chr17	57754344	57754394	+	CDS,intron-Distal	4.89217	48.27813	K562	FMR1
chr17	57754344	57754395	+	CDS,intron-Distal	4.99647	46.96702	K562	FXR2
chr17	57737925	57737951	+	3'-UTR,CDS,intron-Distal,intron-Proximal	5.52836	44.67950	K562	LIN28B
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 595 entries

eCLIP assay for CLTC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CLTC is not available on ENCORE database.
84 RBPs can affect the levels of CLTC.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CLTC is not available on ENCORE database.

84 RBPs can affect the gene expression of CLTC :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CLTC	ENSG00000141367.7	5508.19260	10428.65490	-0.92090	42.49280	40.61990	HepG2	TRIM56
CLTC	ENSG00000141367.7	20330.19670	13150.25670	0.62840	38.97460	37.54270	HepG2	ZNF622
CLTC	ENSG00000141367.7	22365.69050	13974.04200	0.67840	29.13280	27.95790	HepG2	SRSF1
CLTC	ENSG00000141367.7	7980.03740	11698.61980	-0.55190	18.83970	16.69250	HepG2	HDGF
CLTC	ENSG00000141367.7	12063.89580	20001.25040	-0.72940	17.92150	15.93720	K562	GRSF1
CLTC	ENSG00000141367.7	6282.27910	9487.83290	-0.59480	16.72410	15.00580	HepG2	PPIL4
CLTC	ENSG00000141367.7	6900.76500	9473.29180	-0.45710	15.58320	14.23980	HepG2	SAFB2
CLTC	ENSG00000141367.7	22460.52510	16745.85300	0.42350	14.02350	12.85030	K562	AGGF1
CLTC	ENSG00000141367.7	6675.80700	11680.14120	-0.80700	13.77410	12.17030	HepG2	XRN2
CLTC	ENSG00000141367.7	8069.96110	10637.49200	-0.39850	10.94010	9.80140	HepG2	HNRNPU
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 92 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CLTC is not available on ENCORE database.

4 RBPs can affect the splicing of CLTC :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CLTC	ENSG00000141367.7	chr17	+	57764361	57764382			57762947	57763169	57767996	57768072	0.10400	0.00000	0.00000	included	HepG2	PRPF8
SE	CLTC	ENSG00000141367.7	chr17	+	57728531	57728677			57725600	57725762	57733214	57733592	-0.06400	0.00000	0.00002	excluded	K562	AQR
SE	CLTC	ENSG00000141367.7	chr17	+	57759597	57759789			57759007	57759200	57759989	57760154	-0.06700	0.00000	0.00000	excluded	K562	AQR
MXE	CLTC	ENSG00000141367.7	chr17	+	57724758	57725027	57725600	57725762	57721636	57721844	57728563	57728677	0.12500	0.00421	0.06358	1included	HepG2	U2AF1
MXE	CLTC	ENSG00000141367.7	chr17	+	57728563	57728677	57733214	57733388	57725600	57725762	57737751	57737949	-0.10000	0.00441	0.06583	2included	HepG2	U2AF1
MXE	CLTC	ENSG00000141367.7	chr17	+	57728563	57728677	57733214	57733388	57725600	57725762	57737751	57737949	-0.10900	0.00445	0.07886	2included	K562	PPIL4
MXE	CLTC	ENSG00000141367.7	chr17	+	57728563	57728677	57733214	57733388	57725600	57725762	57737751	57737949	-0.09100	0.00500	0.06394	2included	K562	U2AF1

Showing 1 to 7 of 7 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CLTC

General Information

Functions

Localization

Domains (AlphaFold: CLTC)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CLTC is not avaliable on ENCORE database.

60 proteins are bound to CLTC RNA:

eCLIP assay for CLTC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CLTC is not available on ENCORE database.

84 RBPs can affect the gene expression of CLTC :

The Knockdown/knockout RNA-Seq assay for CLTC is not available on ENCORE database.

4 RBPs can affect the splicing of CLTC :

The Knockdown/knockout RNA-Seq assay for CLTC is not avaliable on ENCORE database.