SOS2

General Information

Gene Name : SOS2
Gene ID : ENSG00000100485.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SOS2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SOS2	ENSG00000100485.11	12.32	10.06	11.19	ENCSR000AEF
HepG2	SOS2	ENSG00000100485.11	4.88	8.59	6.73	ENCSR985KAT
K562	SOS2	ENSG00000100485.11	6.89	7.65	7.27	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SOS2 is not avaliable on ENCORE database.

Proteins bound to RNA

SOS2 RNA is bound by 10 proteins.

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eCLIP assay for SOS2 is not avaliable on ENCORE database.

10 proteins are bound to SOS2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr14	50584248	50584325	-	3'-UTR,intron-Distal	6.14399	7.94582	K562	PUM2
chr14	50695339	50695356	-	intron-Distal	6.25745	6.80719	K562	WRN
chr14	50695335	50695339	-	intron-Distal	6.25745	6.80719	K562	WRN
chr14	50647291	50647357	-	CDS,intron-Distal	4.13011	6.23296	HepG2	BCLAF1
chr14	50697986	50698073	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.79568	6.05264	HepG2	DDX3X
chr14	50698127	50698220	-	5'-UTR,intron-Distal,intron-Proximal	3.70674	6.02805	HepG2	DDX3X
chr14	50585067	50585115	-	CDS,intron-Distal	4.47406	5.82129	K562	PUM2
chr14	50667669	50667729	-	CDS,intron-Distal,intron-Proximal	4.59193	5.27053	HepG2	PPIG
chr14	50612008	50612051	-	CDS,intron-Distal,intron-Proximal	4.65084	5.23259	HepG2	BCLAF1
chr14	50667668	50667712	-	CDS,intron-Distal,intron-Proximal	4.00398	4.51739	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 22 entries

eCLIP assay for SOS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SOS2 is not available on ENCORE database.
71 RBPs can affect the levels of SOS2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SOS2 is not available on ENCORE database.

71 RBPs can affect the gene expression of SOS2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SOS2	ENSG00000100485.7	1687.84580	932.13340	0.85650	25.21240	24.09660	HepG2	SRFBP1
SOS2	ENSG00000100485.7	1487.99690	987.38540	0.59160	10.77350	9.71270	HepG2	ETF1
SOS2	ENSG00000100485.7	1280.94830	825.27830	0.63420	10.31190	9.45380	HepG2	RBM22
SOS2	ENSG00000100485.7	1381.15610	982.72300	0.49090	9.69060	8.82370	HepG2	ZNF622
SOS2	ENSG00000100485.7	799.44750	1155.59830	-0.53160	7.96550	7.07240	K562	AGGF1
SOS2	ENSG00000100485.7	786.24210	1161.91560	-0.56350	7.65470	6.69850	K562	RBM15
SOS2	ENSG00000100485.7	950.85080	1429.59310	-0.58830	8.38600	6.62290	K562	MBNL1
SOS2	ENSG00000100485.7	1257.10060	806.22810	0.64070	7.29230	6.27940	HepG2	U2AF1
SOS2	ENSG00000100485.7	797.98960	1202.43640	-0.59150	6.71220	5.66140	K562	AKAP8L
SOS2	ENSG00000100485.7	601.96440	960.44390	-0.67400	6.33140	5.31030	HepG2	FXR1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 77 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SOS2 is not available on ENCORE database.

3 RBPs can affect the splicing of SOS2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SOS2	ENSG00000100485.7	chr14	-	50586992	50587102			50583846	50585571	50596678	50596720	-0.14200	0.00008	0.00158	excluded	HepG2	U2AF2
MXE	SOS2	ENSG00000100485.7	chr14	-	50625282	50625364	50626148	50626804	50623716	50623839	50628199	50628327	-0.21400	0.00012	0.00132	2included	HepG2	U2AF2
SE	SOS2	ENSG00000100485.7	chr14	-	50586992	50587102			50583846	50585571	50596678	50596720	-0.09200	0.00139	0.02230	excluded	K562	PUS1
A3SS	SOS2	ENSG00000100485.7	chr14	-	50612194	50612344			50612194	50612314	50616725	50616948	0.21000	0.00497	0.02871	longer	K562	AQR
MXE	SOS2	ENSG00000100485.7	chr14	-	50611887	50612050	50612194	50612344	50606659	50606777	50616725	50616948	0.17400	0.00724	0.04880	1included	K562	AQR
A3SS	SOS2	ENSG00000100485.7	chr14	-	50647289	50647449			50647289	50647400	50649180	50649324	0.06400	0.01710	0.08356	longer	K562	AQR

Showing 1 to 6 of 6 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SOS2

General Information

Functions

Localization

Domains (AlphaFold: SOS2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SOS2 is not avaliable on ENCORE database.

10 proteins are bound to SOS2 RNA:

eCLIP assay for SOS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SOS2 is not available on ENCORE database.

71 RBPs can affect the gene expression of SOS2 :

The Knockdown/knockout RNA-Seq assay for SOS2 is not available on ENCORE database.

3 RBPs can affect the splicing of SOS2 :

The Knockdown/knockout RNA-Seq assay for SOS2 is not avaliable on ENCORE database.