CDK11B

General Information

Gene Name : CDK11B
Gene ID : ENSG00000248333.8
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CDK11B)

Not Available

Antibody Validation

Cell Signaling Technology: 5524S

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CDK11B	ENSG00000248333.8	27.65	21.06	24.35	ENCSR000AEF
HepG2	CDK11B	ENSG00000248333.8	23.43	20.02	21.73	ENCSR985KAT
K562	CDK11B	ENSG00000248333.8	36.73	35.12	35.92	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CDK11B		5524S	3			Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
CDK11B	K562	CRISPR			CDK11B-BGKcLV42-15,CDK11B-BGKcLV42-16	NT-BGKcLV42-1,NT-BGKcLV42-2	50.3,52.4	Submitting	ENCORE2
CDK11B	HepG2	CRISPR			CDK11B-BGHcLV45-11,CDK11B-BGHcLV45-12	NT-BGHcLV45-1,NT-BGHcLV45-2	67.8,60.8	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CDK11B	Product_ID: 5524S Lot_ID: 3 Source: Cell Signaling Technology Target Name: CDK11B-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CDK11B is not avaliable on ENCORE database.

Proteins bound to RNA

CDK11B RNA is bound by 12 proteins.

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eCLIP assay for CDK11B is not avaliable on ENCORE database.

12 proteins are bound to CDK11B RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	1572752	1572765	-	intron-Distal,intron-Proximal	6.12269	30.58090	HepG2	PRPF8
chr1	1572731	1572752	-	intron-Distal,intron-Proximal	5.19753	29.86178	HepG2	PRPF8
chr1	1572765	1572770	-	intron-Distal,intron-Proximal	5.47841	27.94932	HepG2	PRPF8
chr1	1572695	1572770	-	intron-Distal,intron-Proximal	5.79827	24.96343	K562	AQR
chr1	1582717	1582806	-	intron-Distal	3.93412	21.81386	K562	SLTM
chr1	1583414	1583481	-	intron-Distal	4.93557	18.06942	K562	SLTM
chr1	1582705	1582801	-	intron-Distal	4.60622	16.39540	K562	SAFB2
chr1	1582701	1582805	-	intron-Distal	4.30488	15.36400	K562	UCHL5
chr1	1586865	1586937	-	CDS,intron-Distal	4.94039	13.64917	K562	UCHL5
chr1	1572710	1572731	-	intron-Distal,intron-Proximal	3.77132	11.43407	HepG2	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 53 entries

eCLIP assay for CDK11B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CDK11B is not available on ENCORE database.
67 RBPs can affect the levels of CDK11B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CDK11B is not available on ENCORE database.

67 RBPs can affect the gene expression of CDK11B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDK11B	ENSG00000248333.3	1519.55900	636.41830	1.25550	22.97560	20.79810	K562	PRPF8
CDK11B	ENSG00000248333.3	1279.55550	653.99560	0.96820	13.96410	11.74420	K562	EFTUD2
CDK11B	ENSG00000248333.3	1096.59270	522.28450	1.07000	12.79090	10.59380	K562	PCBP2
CDK11B	ENSG00000248333.3	861.75380	456.19040	0.91750	10.89030	9.58420	HepG2	HNRNPK
CDK11B	ENSG00000248333.3	1383.84190	695.98700	0.99140	10.81990	9.42200	HepG2	SF3A3
CDK11B	ENSG00000248333.3	1161.20830	565.91830	1.03690	10.82730	9.27050	K562	TARDBP
CDK11B	ENSG00000248333.3	2744.04530	1764.14530	0.63720	9.30520	8.33120	K562	AQR
CDK11B	ENSG00000248333.3	161.84340	383.37210	-1.24410	9.45050	7.98930	K562	G3BP2
CDK11B	ENSG00000248333.3	1041.58350	570.46280	0.86850	8.77310	7.63320	K562	PTBP1
CDK11B	ENSG00000248333.3	327.65200	545.45790	-0.73530	7.73800	7.03960	HepG2	SRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 74 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CDK11B is not available on ENCORE database.

1 RBPs can affect the splicing of CDK11B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	is_included	Cell Line	Affected by RBP
A3SS	CDK11B	ENSG00000248333.3	chr1	-	1572769	1572997	1572769	1572875	1573123	1573245	0.27700	longer	K562	AQR
A3SS	CDK11B	ENSG00000248333.3	chr1	-	1571694	1571897	1571694	1571843	1572043	1572072	0.25700	longer	K562	AQR
A3SS	CDK11B	ENSG00000248333.3	chr1	-	1572442	1572597	1572442	1572564	1572769	1572890	0.13800	longer	K562	AQR

Showing 1 to 3 of 3 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CDK11B

General Information

Functions

Localization

Domains (AlphaFold: CDK11B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CDK11B is not avaliable on ENCORE database.

12 proteins are bound to CDK11B RNA:

eCLIP assay for CDK11B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CDK11B is not available on ENCORE database.

67 RBPs can affect the gene expression of CDK11B :

The Knockdown/knockout RNA-Seq assay for CDK11B is not available on ENCORE database.

1 RBPs can affect the splicing of CDK11B :

The Knockdown/knockout RNA-Seq assay for CDK11B is not avaliable on ENCORE database.