ADK

General Information

Gene Name : ADK
Gene ID : ENSG00000156110.13
Essential Gene : No

Functions

Other

Localization

Not Available

Domains (AlphaFold: ADK)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

Bethyl Labs: A304-280A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ADK	ENSG00000156110.13	66.79	58.37	62.58	ENCSR000AEF
HepG2	ADK	ENSG00000156110.13	40.87	67.92	54.39	ENCSR985KAT
K562	ADK	ENSG00000156110.13	56.21	53.07	54.64	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	ADK-BGKcLV26-K562	ENCSR812JYP	ADK	K562	Released		ENCSR900GQL	CRISPR	KD% = 61.3,69.9
knockdown followed by RNA-seq	ADK-BGHcLV25-HepG2	ENCSR924AVW	ADK	HepG2	Released		ENCSR953VMB	CRISPR	KD% = 87.8,90.9

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
ADK	ENCAB355LKV	A304-280A	1				BGHcLV25-15, Released, ENCODE4	BGKcLV26-11, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
ADK	K562	CRISPR	ENCSR812JYP	ENCSR900GQL	ADK-BGKcLV26-11,ADK-BGKcLV26-12	NT-BGKcLV26-1,NT-BGKcLV26-2	61.3,69.9	Released	ENCODE4
ADK	HepG2	CRISPR	ENCSR924AVW	ENCSR953VMB	ADK-BGHcLV25-15,ADK-BGHcLV25-16	NT-BGHcLV25-1,NT-BGHcLV25-2	87.8,90.9	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
ADK	Product_ID: A304-280A Lot_ID: 1 Source: Bethyl Labs Target Name: ADK-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ADK is not avaliable on ENCORE database.

Proteins bound to RNA

ADK RNA is bound by 44 proteins.

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eCLIP assay for ADK is not avaliable on ENCORE database.

44 proteins are bound to ADK RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr10	75945979	75946110	+	intron-Distal	6.17865	72.69251	HepG2	PCBP2
chr10	76234285	76234346	+	intron-Distal	7.88901	57.24112	HepG2	PTBP1
chr10	76082496	76082653	+	intron-Distal	5.60740	33.90090	HepG2	PCBP2
chr10	76234235	76234285	+	intron-Distal	5.94346	27.81650	HepG2	PTBP1
chr10	76082458	76082569	+	intron-Distal	5.18000	24.31508	HepG2	PTBP1
chr10	76234286	76234348	+	intron-Distal	5.96626	23.73501	K562	PTBP1
chr10	76167121	76167251	+	intron-Distal	4.39043	23.14952	K562	KHSRP
chr10	76082562	76082641	+	intron-Distal	6.66935	21.86862	K562	PTBP1
chr10	75936516	75936643	+	5'-UTR,CDS,intron-Distal	3.77452	20.58890	K562	DDX3X
chr10	76096933	76097084	+	intron-Distal	4.25610	17.13548	K562	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 268 entries

eCLIP assay for ADK is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ADK is not available on ENCORE database.
126 RBPs can affect the levels of ADK.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ADK is not available on ENCORE database.

126 RBPs can affect the gene expression of ADK :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ADK	ENSG00000156110.9	661.33450	1950.39040	-1.56030	38.22300	36.25280	K562	AQR
ADK	ENSG00000156110.9	676.81850	1363.48610	-1.01050	22.05090	20.53440	HepG2	QKI
ADK	ENSG00000156110.9	612.09450	1113.08610	-0.86270	19.54200	18.31870	HepG2	SRSF9
ADK	ENSG00000156110.9	460.46950	1117.95230	-1.27970	19.78170	18.29720	HepG2	EIF2S1
ADK	ENSG00000156110.9	486.93280	1003.95200	-1.04390	17.08810	15.68350	K562	HNRNPC
ADK	ENSG00000156110.9	672.83270	1182.08250	-0.81300	16.35120	14.49810	K562	SF3A3
ADK	ENSG00000156110.9	312.75990	669.87950	-1.09880	15.75210	13.84710	K562	CPSF6
ADK	ENSG00000156110.9	442.39860	1245.55060	-1.49340	15.60190	13.16140	K562	CNOT7
ADK	ENSG00000156110.9	968.42180	1466.48120	-0.59870	14.14000	13.01740	HepG2	PUM1
ADK	ENSG00000156110.9	1358.57580	2444.35060	-0.84740	14.44640	12.08520	K562	MSI2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 154 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ADK is not available on ENCORE database.

19 RBPs can affect the splicing of ADK :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	ADK	ENSG00000156110.9	chr10	+	76285013	76285184			76158228	76158337	76349039	76349075	-0.14400	0.00000	0.00000	excluded	HepG2	SRSF1
SE	ADK	ENSG00000156110.9	chr10	+	76285013	76285184			76158228	76158337	76349039	76349075	-0.11800	0.00000	0.00014	excluded	HepG2	SF3A3
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	-0.23200	0.00000	0.00000	2included	K562	PUS1
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	0.28900	0.00000	0.00029	1included	K562	FXR1
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	0.24000	0.00000	0.00031	1included	K562	EWSR1
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	0.19000	0.00002	0.03694	1included	K562	AKAP1
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	0.18900	0.00002	0.03686	1included	K562	DDX3X
MXE	ADK	ENSG00000156110.9	chr10	+	75960521	75960596	75984295	75984349	75910959	75911101	76074424	76074503	0.22000	0.00002	0.00260	1included	HepG2	DDX6
SE	ADK	ENSG00000156110.9	chr10	+	75934173	75934376			75910992	75911101	75960521	75960596	0.11800	0.00004	0.01041	included	HepG2	RBFOX2
SE	ADK	ENSG00000156110.9	chr10	+	76285013	76285184			76158228	76158337	76349039	76349075	-0.05400	0.00006	0.00166	excluded	K562	PUS1

Showing 1 to 10 of 25 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ADK

General Information

Functions

Localization

Domains (AlphaFold: ADK)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ADK is not avaliable on ENCORE database.

44 proteins are bound to ADK RNA:

eCLIP assay for ADK is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ADK is not available on ENCORE database.

126 RBPs can affect the gene expression of ADK :

The Knockdown/knockout RNA-Seq assay for ADK is not available on ENCORE database.

19 RBPs can affect the splicing of ADK :

The Knockdown/knockout RNA-Seq assay for ADK is not avaliable on ENCORE database.