CMTR1

General Information

Gene Name : CMTR1
Gene ID : ENSG00000137200.12
Essential Gene : Yes

Functions

Other

Localization(RBPImage: CMTR1)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Speckles
Cytoplasm
Cytosolic
Nuclear release mitosis

Domains (AlphaFold: CMTR1)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

View validation images for all CMTR1 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CMTR1	ENSG00000137200.12	37.33	39.14	38.23	ENCSR000AEF
HepG2	CMTR1	ENSG00000137200.12	30.34	35.50	32.92	ENCSR985KAT
K562	CMTR1	ENSG00000137200.12	43.56	41.62	42.59	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CMTR1-BGKcLV28-K562	ENCSR697NDQ	CMTR1	K562	Released		ENCSR220DTX	CRISPR	KD% = 70.2,71.1
knockdown followed by RNA-seq	CMTR1-BGHcLV29-HepG2	ENCSR244OOV	CMTR1	HepG2	Released		ENCSR462MFN	CRISPR	KD% = 76.9,75.9

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CMTR1	ENCAB701WNM	A300-303A	2	Released, ENCODE4		BGKcLV28-25, Released, ENCODE4
CMTR1	ENCAB409TEB	A300-304A	1	Released, ENCODE4	BGHcLV29-25, Experimented, ENCORE2	BGKcLV28-25, Released, ENCODE4
CMTR1	ENCAB701WNM	A300-303A	1	Released, ENCODE4	BGHcLV29-25, Experimented, ENCORE2	BGKcLV28-25, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
CMTR1	K562	CRISPR	ENCSR697NDQ	ENCSR220DTX	CMTR1-BGKcLV28-25,CMTR1-BGKcLV28-26	NT-BGKcLV28-1,NT-BGKcLV28-2	70.2,71.1	Released	ENCODE4
CMTR1	HepG2	CRISPR	ENCSR244OOV	ENCSR462MFN	CMTR1-BGHcLV29-25,CMTR1-BGHcLV29-26	NT-BGHcLV29-1,NT-BGHcLV29-2	76.9,75.9	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

CMTR1: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Speckles

Cytoplasm

Cytosolic

Nuclear release mitosis

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CMTR1	Product_ID: A300-303A Lot_ID: 1 Source: Bethyl Labs Target Name: CMTR1-human
CMTR1	Product_ID: A300-304A Lot_ID: 1 Source: Bethyl Labs Target Name: CMTR1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CMTR1 is not avaliable on ENCORE database.

Proteins bound to RNA

CMTR1 RNA is bound by 24 proteins.

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eCLIP assay for CMTR1 is not avaliable on ENCORE database.

24 proteins are bound to CMTR1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	37427362	37427438	+	CDS	7.69465	66.27946	K562	LIN28B
chr6	37449006	37449092	+	3'-UTR,intron-Distal	4.72292	32.67524	K562	UPF1
chr6	37420822	37420918	+	CDS,intron-Distal,intron-Proximal	4.64806	25.84028	K562	DDX24
chr6	37448463	37448539	+	3'-UTR,intron-Distal	4.15109	24.24974	K562	UPF1
chr6	37427339	37427415	+	CDS,intron-Proximal	5.06888	24.04460	HepG2	LIN28B
chr6	37448341	37448407	+	3'-UTR,intron-Distal	4.34088	21.91183	K562	UPF1
chr6	37448869	37448973	+	3'-UTR,intron-Distal	4.89427	20.03105	K562	UPF1
chr6	37448663	37448742	+	3'-UTR,intron-Distal	4.10692	18.81113	K562	UPF1
chr6	37448572	37448632	+	3'-UTR,intron-Distal	5.36317	18.66766	K562	UPF1
chr6	37443848	37443913	+	5'-UTR,CDS,intron-Proximal	3.53251	18.12075	K562	SF3B4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 92 entries

eCLIP assay for CMTR1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CMTR1 is not available on ENCORE database.
51 RBPs can affect the levels of CMTR1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CMTR1 is not available on ENCORE database.

51 RBPs can affect the gene expression of CMTR1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CMTR1	ENSG00000137200.8	747.81590	1389.45800	-0.89380	23.89300	22.24880	HepG2	HNRNPU
CMTR1	ENSG00000137200.8	942.55590	2007.20730	-1.09050	18.45060	16.64270	HepG2	ASCC1
CMTR1	ENSG00000137200.8	1008.01060	2064.75210	-1.03450	11.64950	10.28570	HepG2	EIF4B
CMTR1	ENSG00000137200.8	1357.42090	2130.64430	-0.65040	11.45950	10.14450	HepG2	PUM2
CMTR1	ENSG00000137200.8	2563.49590	3854.71070	-0.58850	8.62800	7.68510	K562	AQR
CMTR1	ENSG00000137200.8	961.70210	1389.45510	-0.53090	8.87690	7.60330	HepG2	PRPF4
CMTR1	ENSG00000137200.8	2126.38380	2861.09220	-0.42820	8.49140	7.53810	HepG2	ETF1
CMTR1	ENSG00000137200.8	1395.99580	2048.67250	-0.55340	8.66850	7.23170	K562	U2AF2
CMTR1	ENSG00000137200.8	1332.02580	2008.56360	-0.59250	8.06850	7.12240	HepG2	PUF60
CMTR1	ENSG00000137200.8	859.47900	1440.64270	-0.74520	8.05260	6.99510	HepG2	SUPV3L1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 56 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CMTR1 is not available on ENCORE database.

6 RBPs can affect the splicing of CMTR1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	CMTR1	ENSG00000137200.8	chr6	+	37418008	37418119	37418026	37418119	37414066	37414225	0.07800	0.00000	0.00000	longer	K562	AQR
A3SS	CMTR1	ENSG00000137200.8	chr6	+	37441220	37441377	37441245	37441377	37440155	37440263	0.05900	0.00000	0.00002	longer	K562	AQR
A5SS	CMTR1	ENSG00000137200.8	chr6	+	37446184	37446403	37446184	37446297	37446922	37447031	0.05200	0.00000	0.00000	longer	K562	AQR
A3SS	CMTR1	ENSG00000137200.8	chr6	+	37445331	37445415	37445367	37445415	37443845	37443970	0.07700	0.00001	0.00013	longer	K562	AQR
A5SS	CMTR1	ENSG00000137200.8	chr6	+	37446184	37446403	37446184	37446297	37446922	37447031	0.06600	0.00001	0.00192	longer	K562	PRPF8
SE	CMTR1	ENSG00000137200.8	chr6	+	37429745	37429878	37429324	37429421	37430604	37430784	-0.16600	0.00007	0.00206	excluded	K562	U2AF2
A3SS	CMTR1	ENSG00000137200.8	chr6	+	37441220	37441377	37441245	37441377	37440194	37440263	0.05900	0.00012	0.00669	longer	K562	U2AF2
SE	CMTR1	ENSG00000137200.8	chr6	+	37443901	37443970	37443094	37443188	37445367	37445415	-0.10500	0.00025	0.00623	excluded	K562	U2AF2
A5SS	CMTR1	ENSG00000137200.8	chr6	+	37443096	37443692	37443096	37443188	37443901	37443970	0.12600	0.00083	0.08926	longer	K562	RBM22
A5SS	CMTR1	ENSG00000137200.8	chr6	+	37443094	37443207	37443094	37443188	37443901	37443970	0.05600	0.00165	0.05823	longer	K562	PUS1

Showing 1 to 10 of 11 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CMTR1

General Information

Functions

Localization(RBPImage: CMTR1)

Domains (AlphaFold: CMTR1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CMTR1 is not avaliable on ENCORE database.

24 proteins are bound to CMTR1 RNA:

eCLIP assay for CMTR1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CMTR1 is not available on ENCORE database.

51 RBPs can affect the gene expression of CMTR1 :

The Knockdown/knockout RNA-Seq assay for CMTR1 is not available on ENCORE database.

6 RBPs can affect the splicing of CMTR1 :

The Knockdown/knockout RNA-Seq assay for CMTR1 is not avaliable on ENCORE database.