UNC50

General Information

Gene Name       : UNC50
Gene ID             : ENSG00000115446.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: UNC50)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UNC50ENSG00000115446.1126.7423.6825.21ENCSR000AEF
HepG2UNC50ENSG00000115446.1145.8976.9861.44ENCSR985KAT
K562UNC50ENSG00000115446.1127.3524.1325.74ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UNC50 is not avaliable on ENCORE database.



Proteins bound to RNA
  • UNC50 RNA is bound by 15 proteins.  







eCLIP assay for UNC50 is not avaliable on ENCORE database.





15 proteins are bound to UNC50 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr29923483799234903+3'-UTR6.1468414.77516K562PUM2
chr29923490399234949+3'-UTR5.240313.29542K562PUM2
chr29922506899225138+5'-UTR4.92198400.00000HepG2DDX3X
chr29922509899225164+5'-UTR4.1588115.58190HepG2GTF2F1
chr29922621699226233+5'-UTR,CDS,intron-Proximal4.336803.03048HepG2GTF2F1
chr29922513899225191+5'-UTR,intron-Proximal4.38280400.00000HepG2DDX3X
chr29922505899225192+5'-UTR,intron-Proximal3.4182913.01358K562DDX3X
chr29922512799225235+5'-UTR,intron-Proximal3.742524.65702K562GEMIN5
chr29922507799225195+5'-UTR,intron-Proximal3.323087.58927HepG2GRSF1
chr29922514299225198+5'-UTR,intron-Proximal4.7092425.96982HepG2PRPF4
chr29922514299225199+5'-UTR,intron-Proximal3.4894514.30525HepG2NCBP2
chr29922516499225206+5'-UTR,intron-Proximal4.8652719.26361HepG2GTF2F1
chr29922508199225187+5'-UTR3.594083.76888K562NCBP2
chr29922607999226138+5'-UTR,intron-Distal,intron-Proximal4.5793713.33368HepG2U2AF2
chr29922508599225142+5'-UTR3.7813913.29275HepG2PRPF4
chr29922621799226302+5'-UTR,CDS,intron-Proximal3.4354926.59469HepG2DDX3X
chr29923265899232695+CDS,intron-Proximal3.141895.79202HepG2U2AF2
chr29922718099227244+CDS,intron-Proximal5.509706.91748K562SF3B4
chr29922648599226538+CDS,intron-Proximal4.426155.43815HepG2PRPF8
chr29923091499231001+intron-Distal3.665943.54854K562HNRNPU
chr29923059599230639+intron-Distal4.614405.44484K562RBFOX2
chr29923091999230976+intron-Distal3.312373.73564K562RBFOX2
chr29923230099232381+intron-Distal4.457737.96448K562PTBP1
chr29923053699230598+intron-Distal3.6251814.78412HepG2RBFOX2
chr29923136499231417+intron-Distal3.720676.46902HepG2U2AF2
chr29922658899226643+intron-Distal,intron-Proximal3.995623.12843K562PRPF8
chr29923086099230902+intron-Distal4.134303.25414K562RBFOX2
chr29923231999232396+intron-Distal4.775529.88335HepG2PTBP1
chr29923081499230860+intron-Distal3.534174.14505K562RBFOX2
chr29923053599230595+intron-Distal4.323118.00221K562RBFOX2
chr29923233299232393+intron-Distal3.251103.76460HepG2HNRNPL
chr29923134399231364+intron-Distal4.145825.09028HepG2U2AF2
chr29923232299232415+intron-Distal3.386373.79878K562MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UNC50 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UNC50 is not available on ENCORE database.

  • 42 RBPs can affect the levels of UNC50.  








The Knockdown/knockout RNA-Seq assay for UNC50 is not available on ENCORE database.





42 RBPs can affect the gene expression of UNC50 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UNC50ENSG00000115446.72249.931201382.663800.702307.257606.44060HepG2AKAP1
UNC50ENSG00000115446.7558.40730748.80050-0.423302.164301.36670HepG2BCLAF1
UNC50ENSG00000115446.7777.72210479.984400.696206.981706.07990HepG2BOP1
UNC50ENSG00000115446.71346.267301086.930400.308602.023801.35590HepG2CIRBP
UNC50ENSG00000115446.71259.82420845.536500.575203.234702.40240HepG2CNOT7
UNC50ENSG00000115446.71439.192101203.294900.258202.487201.87160HepG2CELF1
UNC50ENSG00000115446.71789.461201324.539900.433903.491002.79830HepG2DDX3X
UNC50ENSG00000115446.7872.399401093.80550-0.326301.950701.44290HepG2EIF2S1
UNC50ENSG00000115446.7363.93990499.49950-0.456802.323001.73380HepG2GPKOW
UNC50ENSG00000115446.7788.989601145.37570-0.537704.936304.02470HepG2HNRNPK
UNC50ENSG00000115446.7864.142001178.64020-0.447806.094905.12910HepG2HNRNPL
UNC50ENSG00000115446.7614.44570768.96100-0.323602.923402.30200HepG2HNRNPU
UNC50ENSG00000115446.7948.565101219.91700-0.363002.324201.72180HepG2MAGOH
UNC50ENSG00000115446.7821.86390659.325400.317802.145901.42890HepG2MSI2
UNC50ENSG00000115446.7458.56570777.89130-0.762403.739502.45330HepG2NONO
UNC50ENSG00000115446.7915.181701105.25110-0.272202.576901.98560HepG2PCBP1
UNC50ENSG00000115446.7563.54340685.85760-0.283402.009701.37270HepG2PPIL4
UNC50ENSG00000115446.7936.045701124.64110-0.264802.360601.84850HepG2PTBP1
UNC50ENSG00000115446.7977.548501165.71660-0.254002.298401.73020HepG2RECQL
UNC50ENSG00000115446.7393.49930522.48840-0.409002.604002.00660HepG2RPS19
UNC50ENSG00000115446.7589.29000823.50300-0.482802.318201.70100HepG2SF3A3
UNC50ENSG00000115446.7975.173801174.29660-0.268102.967402.24300HepG2SLBP
UNC50ENSG00000115446.7612.36330798.64120-0.383202.684402.04740HepG2SMN1
UNC50ENSG00000115446.71763.995101448.356400.284302.796802.29320HepG2SRFBP1
UNC50ENSG00000115446.7990.052401375.23810-0.474108.478407.48900HepG2SUCLG1
UNC50ENSG00000115446.7815.596501098.53410-0.429704.940004.22500HepG2TAF15
UNC50ENSG00000115446.7805.406201009.38860-0.325702.616801.80290HepG2TIA1
UNC50ENSG00000115446.7595.07960747.31420-0.328602.327301.86050HepG2TIAL1
UNC50ENSG00000115446.7594.35020753.86060-0.343003.151102.55820HepG2TRIM56
UNC50ENSG00000115446.7338.04020468.05380-0.469503.487002.86290K562AGGF1
UNC50ENSG00000115446.7368.68770487.02560-0.401602.338401.73640K562AKAP8L
UNC50ENSG00000115446.7281.80310386.32350-0.455102.954301.96460K562BCLAF1
UNC50ENSG00000115446.7106.75600166.20330-0.638602.354401.39820K562CCAR1
UNC50ENSG00000115446.7470.21180315.309800.576404.637303.88130K562FXR1
UNC50ENSG00000115446.7441.77890290.092400.606703.272502.49200K562G3BP2
UNC50ENSG00000115446.7405.61860295.669400.456002.232901.40070K562HNRNPM
UNC50ENSG00000115446.7642.91910487.288700.399802.498801.73930K562HSPD1
UNC50ENSG00000115446.7438.63830303.655800.530503.041902.25430K562PRPF8
UNC50ENSG00000115446.7996.76280818.297100.284502.150601.43220K562PUF60
UNC50ENSG00000115446.71174.23000870.244800.432104.851903.40730K562PUM1
UNC50ENSG00000115446.7287.78210483.03560-0.747206.107305.33910K562PUS1
UNC50ENSG00000115446.7326.15980470.61240-0.529003.992103.29590K562RBM15
UNC50ENSG00000115446.7240.67690156.950400.616702.363001.44630K562RPS3
UNC50ENSG00000115446.7537.83740713.98260-0.408702.858001.32540K562SUCLG1
UNC50ENSG00000115446.7177.19420250.53430-0.499702.221701.38760K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UNC50 is not available on ENCORE database.





20 RBPs can affect the splicing of UNC50 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUNC50ENSG00000115446.7chr2+992326699923280999227237992273589923289499232996-0.179000.000000.00000excludedK562AQR
A3SSUNC50ENSG00000115446.7chr2+9923460899234978992346309923497899232894992329960.181000.000000.00012longerK562U2AF2
A3SSUNC50ENSG00000115446.7chr2+9923460899234978992346309923497899232894992329960.100000.000000.00002longerHepG2U2AF2
A3SSUNC50ENSG00000115446.7chr2+9923460899234978992346309923497899232841992329960.124000.000000.00000longerK562AQR
A3SSUNC50ENSG00000115446.7chr2+9923460899234978992346309923497899232894992329960.064000.000150.00781longerHepG2U2AF1
A3SSUNC50ENSG00000115446.7chr2+9923460899234978992346309923497899232894992329960.147000.000060.00423longerK562U2AF1
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.222000.000340.02337excludedHepG2SFPQ
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.103000.000020.02507excludedHepG2TROVE2
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.065000.000000.00019excludedHepG2BCCIP
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.104000.005980.03616includedK562PUS1
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.110000.000000.00006includedHepG2SF3A3
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.239000.000000.00048includedK562SF3B1
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.055000.000950.03479includedHepG2TIA1
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.180000.000000.00011excludedK562SRSF1
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.144000.000070.01617includedK562SRSF7
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.115000.000000.00000includedHepG2TAF15
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.095000.000000.00003includedHepG2NCBP2
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.106000.000000.00000includedHepG2SF3B4
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.076000.000190.00563includedHepG2FUBP3
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.079000.000030.00077includedHepG2HNRNPK
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.102000.005830.05833includedK562UTP18
RIUNC50ENSG00000115446.7chr2+9922504199226502992250419922518999226218992265020.261000.000000.00000includedK562AQR
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.060000.000030.00292excludedHepG2XRN2
RIUNC50ENSG00000115446.7chr2+992250419922650299225041992251899922621899226502-0.137000.000090.00268excludedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UNC50 is not avaliable on ENCORE database.