TPMT

General Information

Gene Name       : TPMT
Gene ID             : ENSG00000137364.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TPMT)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TPMTENSG00000137364.415.3212.4113.87ENCSR000AEF
HepG2TPMTENSG00000137364.412.2723.0717.67ENCSR985KAT
K562TPMTENSG00000137364.430.0334.6832.36ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TPMT is not avaliable on ENCORE database.



Proteins bound to RNA
  • TPMT RNA is bound by 7 proteins.  







eCLIP assay for TPMT is not avaliable on ENCORE database.





7 proteins are bound to TPMT RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr61813059918130703-3'-UTR,intron-Distal3.308725.47138HepG2SUB1
chr61813073818130856-3'-UTR,intron-Distal4.053017.83342HepG2SUB1
chr61813007218130130-3'-UTR,intron-Distal3.510183.95400K562UPF1
chr61814934718149403-5'-UTR,CDS,intron-Distal,intron-Proximal3.238965.11648K562DDX3X
chr61814921818149405-5'-UTR,CDS,intron-Distal,intron-Proximal4.611055.11007HepG2GRWD1
chr61815525718155304-5'-UTR,intron-Distal5.000637.13477K562DDX3X
chr61814921118149345-CDS,intron-Distal,intron-Proximal5.0694713.34504K562ZNF622
chr61813881218138889-intron-Distal4.517194.17759HepG2QKI
chr61813374918133830-intron-Distal4.247893.45799HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TPMT is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TPMT is not available on ENCORE database.

  • 100 RBPs can affect the levels of TPMT.  








The Knockdown/knockout RNA-Seq assay for TPMT is not available on ENCORE database.





100 RBPs can affect the gene expression of TPMT :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TPMTENSG00000137364.4403.56160579.09500-0.521003.622902.50000HepG2ADAR
TPMTENSG00000137364.4448.10870820.51890-0.8727010.395809.33250HepG2BOP1
TPMTENSG00000137364.41042.50190706.933800.560305.526704.48440HepG2CALR
TPMTENSG00000137364.41386.57540700.621400.9847014.4571012.84860HepG2CIRBP
TPMTENSG00000137364.4583.08780753.29930-0.369502.198801.57750HepG2CPSF6
TPMTENSG00000137364.4666.01740457.527700.541603.005801.57320HepG2CSTF2T
TPMTENSG00000137364.4851.80820493.514400.787309.098807.94190HepG2DDX21
TPMTENSG00000137364.4736.43280482.659100.609405.876804.54780HepG2DDX24
TPMTENSG00000137364.41088.77210853.783800.350702.137601.58130HepG2DDX3X
TPMTENSG00000137364.41065.45480717.289700.570704.878903.88630HepG2DDX55
TPMTENSG00000137364.4821.22180588.687600.480203.461202.34050HepG2DDX5
TPMTENSG00000137364.4830.62930546.369300.604208.010206.97160HepG2DKC1
TPMTENSG00000137364.4414.88740583.13340-0.491104.394603.52430HepG2DNAJC21
TPMTENSG00000137364.4548.01280705.05520-0.363501.917501.41370HepG2EIF2S1
TPMTENSG00000137364.4650.45100462.175400.492903.314302.33050HepG2EIF3D
TPMTENSG00000137364.4642.60090465.856100.463903.552202.34760HepG2EIF3G
TPMTENSG00000137364.41246.74840779.211300.678006.184805.23360HepG2EIF4A3
TPMTENSG00000137364.4616.15160914.35960-0.569505.511804.38370HepG2EIF4G2
TPMTENSG00000137364.4829.44880557.999400.571804.871403.76950HepG2EWSR1
TPMTENSG00000137364.4627.07150470.153200.415402.754801.61260HepG2FASTKD2
TPMTENSG00000137364.4977.11000663.985200.557304.148503.22110HepG2FIP1L1
TPMTENSG00000137364.4555.22580729.25640-0.393402.192701.59730HepG2G3BP1
TPMTENSG00000137364.41044.49440663.003000.655603.555101.95980HepG2HLTF
TPMTENSG00000137364.4909.89450588.719600.628006.227305.31610HepG2HNRNPA1
TPMTENSG00000137364.4830.04490654.832000.342002.174701.55190HepG2HNRNPC
TPMTENSG00000137364.4657.88720793.98570-0.271302.172501.53170HepG2HNRNPF
TPMTENSG00000137364.4529.81630738.28040-0.478703.362902.59560HepG2HNRNPK
TPMTENSG00000137364.4552.95740881.51750-0.672809.985408.78040HepG2HNRNPL
TPMTENSG00000137364.4616.78880458.269200.428503.414402.36770HepG2HNRNPM
TPMTENSG00000137364.4919.04640611.625300.587406.017604.25790HepG2LIN28B
TPMTENSG00000137364.41015.80880790.758900.361202.043801.49650HepG2MATR3
TPMTENSG00000137364.4808.46300537.621200.588506.248405.07810HepG2MSI2
TPMTENSG00000137364.4593.62760959.51170-0.692704.640103.65250HepG2NOL12
TPMTENSG00000137364.4331.351201055.22610-1.671104.688602.21800HepG2NUFIP2
TPMTENSG00000137364.4907.44210373.911401.2790011.015009.21800HepG2PABPC1
TPMTENSG00000137364.4658.73070484.252700.443803.217102.38940HepG2PRPF4
TPMTENSG00000137364.4806.21670553.608300.542204.664803.64620HepG2PRPF8
TPMTENSG00000137364.4788.78830661.641500.253501.820301.35860HepG2PTBP1
TPMTENSG00000137364.4775.96470971.51570-0.324202.868402.18640HepG2PUM2
TPMTENSG00000137364.4708.35880581.692600.284102.298601.72390HepG2PUS1
TPMTENSG00000137364.4988.07930632.157200.644203.373502.59690HepG2RAVER1
TPMTENSG00000137364.4771.02360570.199000.435202.780701.71780HepG2RCC2
TPMTENSG00000137364.4548.32790685.81940-0.322802.401901.82260HepG2RECQL
TPMTENSG00000137364.4755.03930547.660400.463203.294402.44610HepG2RRP9
TPMTENSG00000137364.41287.11840719.748200.838507.837206.66160HepG2SF3A3
TPMTENSG00000137364.4641.57870897.55870-0.484402.386301.66240HepG2SNRNP70
TPMTENSG00000137364.41783.22230718.990501.3103048.9685047.51890HepG2SRSF1
TPMTENSG00000137364.4696.12810904.22390-0.377304.272903.52460HepG2SRSF5
TPMTENSG00000137364.41019.81520864.699600.237902.105101.64190HepG2SSB
TPMTENSG00000137364.4415.03150632.12200-0.607006.058205.37060HepG2TIAL1
TPMTENSG00000137364.4684.48660894.67380-0.386303.323002.35910HepG2TUFM
TPMTENSG00000137364.4981.59280568.130000.788809.364608.19730HepG2U2AF1
TPMTENSG00000137364.4927.49480616.260500.589708.210407.26790HepG2UTP3
TPMTENSG00000137364.41418.57870702.015401.0148034.8836033.50440HepG2ZNF622
TPMTENSG00000137364.41543.424002528.74160-0.7123010.656208.34240K562ABCF1
TPMTENSG00000137364.4987.100901308.81750-0.407005.192303.07490K562AKAP1
TPMTENSG00000137364.41240.983202943.75810-1.2462029.3315027.62590K562AQR
TPMTENSG00000137364.41181.960801535.62970-0.377604.536702.78570K562BCCIP
TPMTENSG00000137364.41102.397201483.88920-0.428706.371404.88940K562BCLAF1
TPMTENSG00000137364.41255.379701761.34420-0.488604.241502.42260K562BUD13
TPMTENSG00000137364.4439.67090729.38200-0.730306.542304.74550K562CCAR1
TPMTENSG00000137364.41731.999902717.64860-0.649904.130602.79070K562CNOT7
TPMTENSG00000137364.41794.931402475.54460-0.463808.080406.16430K562CPEB4
TPMTENSG00000137364.4771.820701125.75090-0.544506.605204.86980K562CSTF2
TPMTENSG00000137364.42921.282904190.72650-0.520609.681507.90300K562CELF1
TPMTENSG00000137364.41574.926901301.233200.275303.144201.72270K562DDX27
TPMTENSG00000137364.42210.013502561.59040-0.213002.402701.78960K562DDX47
TPMTENSG00000137364.43015.763102542.629700.246102.921202.01870K562DKC1
TPMTENSG00000137364.41212.352501456.65620-0.264902.750601.54720K562EIF2S1
TPMTENSG00000137364.4780.829401385.50240-0.8273012.7600010.95190K562EIF4A3
TPMTENSG00000137364.4946.977001247.71520-0.397904.487802.95620K562EIF4B
TPMTENSG00000137364.42552.152703408.07050-0.417207.299305.78640K562EIF4G2
TPMTENSG00000137364.4849.713901145.26960-0.430604.328002.69680K562EXOSC5
TPMTENSG00000137364.42097.849001616.942000.375502.259101.62860K562G3BP2
TPMTENSG00000137364.41128.771201617.56710-0.519107.945506.09820K562GLRX3
TPMTENSG00000137364.41887.297202666.25600-0.498502.102101.43720K562GRSF1
TPMTENSG00000137364.4945.805001270.97000-0.426303.754301.36350K562GRWD1
TPMTENSG00000137364.4937.152001462.59780-0.642208.645007.64060K562HNRNPC
TPMTENSG00000137364.4974.032701305.94600-0.423103.898602.51740K562HNRNPF
TPMTENSG00000137364.41603.105402314.97820-0.530107.325005.52500K562HNRNPL
TPMTENSG00000137364.42335.236401495.043000.643306.985805.40020K562HNRNPM
TPMTENSG00000137364.41353.803301802.94720-0.413305.644304.35630K562HNRNPU
TPMTENSG00000137364.4924.415901309.89340-0.502802.861901.90960K562KRR1
TPMTENSG00000137364.41026.656001483.07620-0.530604.869002.80890K562LIN28B
TPMTENSG00000137364.41305.824901989.71360-0.607608.788107.24540K562MAGOH
TPMTENSG00000137364.41507.912601985.77470-0.397104.324803.14800K562MATR3
TPMTENSG00000137364.4966.378201497.61240-0.632003.772602.73820K562METAP2
TPMTENSG00000137364.41184.463401700.66860-0.521909.896508.46960K562MTPAP
TPMTENSG00000137364.41358.553101889.55170-0.4760011.6382010.25140K562NSUN2
TPMTENSG00000137364.41243.829202272.33230-0.869403.449602.30800K562PABPN1
TPMTENSG00000137364.41164.148401456.78200-0.323502.047101.33190K562PCBP3
TPMTENSG00000137364.42743.188403501.91130-0.352304.494302.71320K562PNPT1
TPMTENSG00000137364.41697.727802417.17560-0.509703.292201.32940K562PPIL4
TPMTENSG00000137364.41583.413201101.514400.523405.339204.29660K562PRPF8
TPMTENSG00000137364.4907.004201311.32880-0.531805.311704.00380K562PSIP1
TPMTENSG00000137364.41410.545701853.94690-0.394303.674702.69420K562RBM22
TPMTENSG00000137364.4975.966201196.20900-0.293602.284901.38820K562RCC2
TPMTENSG00000137364.41575.566002475.27310-0.651703.524101.75580K562SBDS
TPMTENSG00000137364.4589.56720803.46480-0.446603.299801.90580K562SLBP
TPMTENSG00000137364.4518.883701133.99580-1.1279018.9034015.63400K562SRFBP1
TPMTENSG00000137364.41440.164501910.29870-0.407607.586506.11690K562SRPK2
TPMTENSG00000137364.4787.31320994.74560-0.337402.501701.50820K562SRSF4
TPMTENSG00000137364.4808.113501066.65420-0.400502.479601.52250K562SUPV3L1
TPMTENSG00000137364.41308.641001918.01300-0.551506.114405.03090K562TARDBP
TPMTENSG00000137364.41477.215301850.09930-0.324703.193602.30500K562TIA1
TPMTENSG00000137364.4754.752001261.30430-0.740808.115706.44410K562TIAL1
TPMTENSG00000137364.4868.965901339.73990-0.624607.294905.59850K562TRIM56
TPMTENSG00000137364.41612.682502126.49830-0.399003.450101.87060K562TRIP6
TPMTENSG00000137364.41943.519501619.467700.263102.453701.69680K562U2AF2
TPMTENSG00000137364.42442.403002003.535200.285704.327603.44780K562UPF1
TPMTENSG00000137364.41433.331901972.47370-0.460603.640802.25450K562UTP3
TPMTENSG00000137364.41337.506601714.35610-0.358103.521102.53520K562WDR3
TPMTENSG00000137364.42564.516103487.62120-0.443605.926604.03770K562WRN
TPMTENSG00000137364.42113.041603316.33460-0.6503010.531108.72120K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TPMT is not available on ENCORE database.





6 RBPs can affect the splicing of TPMT :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETPMTENSG00000137364.4chr6-181336401813379718132363181324081813403418134120-0.080000.000650.09027excludedK562FXR2
A3SSTPMTENSG00000137364.4chr6-1813236318132539181323631813240818134034181341200.071000.000000.00000longerK562AQR
MXETPMTENSG00000137364.4chr6-18134034181341201813919318139311181323631813240818139895181399480.057000.000300.003181includedK562AQR
MXETPMTENSG00000137364.4chr6-1813403418134120181391931813926818132363181324081813989518139948-0.063000.000000.000012includedHepG2U2AF2
MXETPMTENSG00000137364.4chr6-18132363181324081813403418134120181285411813101118139193181392680.145000.002580.081171includedK562SAFB
MXETPMTENSG00000137364.4chr6-18132363181324081813403418134120181285411813101118139193181392680.101000.000820.027881includedK562PPIL4
MXETPMTENSG00000137364.4chr6-18143826181439591814805318148146181398951813994818149218181494020.096000.006800.075651includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TPMT is not avaliable on ENCORE database.