THAP7

General Information

Gene Name       : THAP7
Gene ID             : ENSG00000184436.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: THAP7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878THAP7ENSG00000184436.112.217.174.69ENCSR000AEF
HepG2THAP7ENSG00000184436.1115.955.0410.49ENCSR985KAT
K562THAP7ENSG00000184436.1187.4156.5872.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for THAP7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • THAP7 RNA is bound by 15 proteins.  







eCLIP assay for THAP7 is not avaliable on ENCORE database.





15 proteins are bound to THAP7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222135411621354210-3'-UTR,CDS,intron-Distal3.445955.32141K562UPF1
chr222135409621354132-3'-UTR,intron-Distal3.282243.60832K562PABPC4
chr222135413221354216-3'-UTR,CDS,intron-Distal5.1972810.44987K562PABPC4
chr222135612521356205-5'-UTR,CDS,intron-Distal,intron-Proximal4.002098.88978K562DDX3X
chr222135554421355566-CDS,intron-Distal,intron-Proximal4.8908915.04626K562RBM15
chr222135569521355791-CDS,intron-Distal,intron-Proximal5.892238.66363HepG2SF3A3
chr222135452521354580-CDS,intron-Distal,intron-Proximal3.997744.92682K562DDX55
chr222135436221354424-CDS,intron-Distal,intron-Proximal3.609269.71899K562YBX3
chr222135500021355038-CDS,intron-Distal,intron-Proximal4.136165.38267K562DDX55
chr222135557821355714-CDS,intron-Distal,intron-Proximal3.4670818.39963K562DDX3X
chr222135569521355768-CDS,intron-Distal,intron-Proximal3.691759.79645K562SF3B4
chr222135463721354687-CDS,intron-Distal3.756016.54748K562PABPC4
chr222135607521356125-CDS,intron-Distal,intron-Proximal3.421105.28960K562AQR
chr222135451021354573-CDS,intron-Distal,intron-Proximal4.9611018.68443K562RBM15
chr222135470321354742-CDS,intron-Distal4.273457.36824K562RBM15
chr222135458421354630-CDS,intron-Distal4.5663915.59807K562RBM15
chr222135464221354690-CDS,intron-Distal4.199179.21338K562RBM15
chr222135469221354775-CDS,intron-Distal3.7637213.18988K562SF3B4
chr222135569721355772-CDS,intron-Distal,intron-Proximal3.142814.37544HepG2SF3B4
chr222135494021355025-CDS,intron-Distal,intron-Proximal3.877083.79347HepG2GRWD1
chr222135469721354771-CDS,intron-Distal3.424827.62584HepG2BUD13
chr222135469421354753-CDS,intron-Distal4.9016724.72883K562AQR
chr222135435021354424-CDS,intron-Distal,intron-Proximal4.308924.13050K562LIN28B
chr222135496321355028-CDS,intron-Distal,intron-Proximal3.4808512.20374K562RBM15
chr222135466721354796-CDS,intron-Distal3.2907114.03313K562BUD13
chr222135594421356050-intron-Distal,intron-Proximal3.2733214.84796K562DDX3X
chr222135548621355514-intron-Distal,intron-Proximal5.010586.89039K562RBM15
chr222135545121355493-intron-Distal,intron-Proximal3.615606.70109K562PRPF8
chr222135551421355544-intron-Distal,intron-Proximal5.9751516.04835K562RBM15
chr222135526521355294-intron-Distal3.734217.39702K562RBM15
chr222135573521355778-intron-Distal,intron-Proximal5.318799.97537K562RBM15
chr222135512021355164-intron-Distal,intron-Proximal5.4339211.08775K562RBM15
chr222135521021355265-intron-Distal3.9434713.35322K562RBM15
chr222135486221354892-intron-Distal,intron-Proximal5.6566717.48131K562AQR
chr222135593721355988-intron-Distal4.191256.30421K562DDX55
chr222135581321355863-intron-Distal,intron-Proximal5.4720111.94084K562RBM15
chr222135475321354806-intron-Distal4.3178812.08528K562AQR
chr222135574121355840-intron-Distal,intron-Proximal4.678765.83981HepG2RBFOX2
chr222135590021356018-intron-Distal,intron-Proximal3.156063.74534K562SRSF1
chr222135589521355944-intron-Distal,intron-Proximal4.000637.76798K562DDX3X
chr222135489221354897-intron-Distal,intron-Proximal6.0661418.01578K562AQR
chr222135489721354936-intron-Distal,intron-Proximal5.7449542.41807K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for THAP7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for THAP7 is not available on ENCORE database.

  • 118 RBPs can affect the levels of THAP7.  








The Knockdown/knockout RNA-Seq assay for THAP7 is not available on ENCORE database.





118 RBPs can affect the gene expression of THAP7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
THAP7ENSG00000184436.7402.43440251.725000.676803.118302.11570HepG2ABCF1
THAP7ENSG00000184436.7224.34680140.039500.679802.513402.00410HepG2AKAP1
THAP7ENSG00000184436.7189.98440115.859700.713402.812202.02240HepG2ASCC1
THAP7ENSG00000184436.7189.3840077.642101.286305.759304.38520HepG2BCCIP
THAP7ENSG00000184436.7319.76820201.987900.662703.850703.15700HepG2BOP1
THAP7ENSG00000184436.7350.42170218.878700.678903.387202.29740HepG2CCAR1
THAP7ENSG00000184436.7225.03990161.638000.477302.334401.71530HepG2CKAP4
THAP7ENSG00000184436.7108.8339050.063101.120202.873902.09380HepG2CNOT7
THAP7ENSG00000184436.7128.4215066.232900.955204.069102.83250HepG2YBX3
THAP7ENSG00000184436.7134.3776087.631200.616702.280301.68730HepG2CELF1
THAP7ENSG00000184436.7147.1873094.215900.643502.643201.91510HepG2DAZAP1
THAP7ENSG00000184436.7234.47840134.123200.805803.814703.09190HepG2DDX3X
THAP7ENSG00000184436.7203.04280115.271200.816703.475502.79040HepG2DDX6
THAP7ENSG00000184436.7122.5408064.459900.926704.128403.36280HepG2DNAJC2
THAP7ENSG00000184436.7194.82820102.955200.920102.378601.52110HepG2EEF2
THAP7ENSG00000184436.7388.56630279.426800.475603.027902.40340HepG2ETF1
THAP7ENSG00000184436.7128.2464074.721400.779202.806401.62920HepG2FAM120A
THAP7ENSG00000184436.7185.22550123.550600.584102.037501.44070HepG2FXR1
THAP7ENSG00000184436.7207.00250114.568100.853304.043403.24780HepG2G3BP1
THAP7ENSG00000184436.7124.0737074.387200.738002.288301.48080HepG2GEMIN5
THAP7ENSG00000184436.795.8671046.362601.048003.049301.87650HepG2GRSF1
THAP7ENSG00000184436.7106.4821042.433201.327204.966703.07830HepG2HNRNPA0
THAP7ENSG00000184436.7117.4354065.662300.838602.492401.87650HepG2HNRNPA1
THAP7ENSG00000184436.787.5588041.426201.079603.047201.57240HepG2HNRNPAB
THAP7ENSG00000184436.7153.3949072.552701.080005.915505.05740HepG2HNRNPU
THAP7ENSG00000184436.7191.42100116.440600.717102.908802.22020HepG2IGF2BP2
THAP7ENSG00000184436.7151.7681074.110501.034005.659804.64330HepG2ILF2
THAP7ENSG00000184436.7108.3168047.803401.180004.293702.75150HepG2KHDRBS1
THAP7ENSG00000184436.7464.50080231.251501.006107.584006.19430HepG2LARP4
THAP7ENSG00000184436.7136.3671059.489901.196704.774503.28380HepG2LARP7
THAP7ENSG00000184436.7262.68490123.594101.087606.826905.81090HepG2MAGOH
THAP7ENSG00000184436.7288.26290124.272501.213806.549805.61110HepG2MATR3
THAP7ENSG00000184436.7250.67720127.188900.978805.319504.45580HepG2NCBP2
THAP7ENSG00000184436.7130.4637053.783601.278305.471203.46920HepG2NIP7
THAP7ENSG00000184436.7186.1491093.424800.994504.097903.16970HepG2NOL12
THAP7ENSG00000184436.7154.0086083.047400.890903.060901.53260HepG2NOLC1
THAP7ENSG00000184436.7138.8111070.111600.985302.816901.71460HepG2NONO
THAP7ENSG00000184436.7128.8728060.451301.092003.640601.35040HepG2NUSAP1
THAP7ENSG00000184436.7147.1565064.711501.185206.553105.45470HepG2PPIL4
THAP7ENSG00000184436.7151.2479089.184700.761903.036202.41690HepG2PUF60
THAP7ENSG00000184436.7254.3624094.676401.4257015.0642013.90820HepG2PUM1
THAP7ENSG00000184436.7166.6776094.605400.817003.713102.94170HepG2PUM2
THAP7ENSG00000184436.7273.78380164.686500.733205.276304.47510HepG2PUS1
THAP7ENSG00000184436.7225.4914071.740801.6521010.575908.61290HepG2RBM27
THAP7ENSG00000184436.7154.0519058.257301.402802.422401.43260HepG2RCC2
THAP7ENSG00000184436.7143.5704081.324200.819903.039502.39920HepG2RPS19
THAP7ENSG00000184436.7140.7718066.154201.089403.876102.93410HepG2RPS2
THAP7ENSG00000184436.7133.8916050.367301.410406.086904.90550HepG2RPS3A
THAP7ENSG00000184436.7136.4381067.539701.014303.390302.19850HepG2RPS5
THAP7ENSG00000184436.7142.6140064.612401.142106.007405.11380HepG2SAFB2
THAP7ENSG00000184436.7383.06220260.334100.557102.741902.07090HepG2SF3A3
THAP7ENSG00000184436.7221.78720145.879500.604302.849802.25050HepG2SF3B4
THAP7ENSG00000184436.7135.0545085.520300.659102.190501.55410HepG2SLBP
THAP7ENSG00000184436.7131.4453075.350600.802703.215002.53010HepG2SMN1
THAP7ENSG00000184436.7172.6585076.790701.168806.038404.58080HepG2SMNDC1
THAP7ENSG00000184436.7161.86870263.77740-0.704504.493803.89960HepG2SRFBP1
THAP7ENSG00000184436.7102.51410152.26820-0.570801.960601.54350HepG2SRSF1
THAP7ENSG00000184436.7199.1555088.060401.177208.331607.32120HepG2SRSF5
THAP7ENSG00000184436.770.80730123.87970-0.807003.188402.60500HepG2SRSF9
THAP7ENSG00000184436.7294.74330229.013100.363901.775901.34270HepG2SSB
THAP7ENSG00000184436.791.6659043.847001.063803.546802.28780HepG2STIP1
THAP7ENSG00000184436.7231.60060100.145901.2094010.031008.97060HepG2SUCLG1
THAP7ENSG00000184436.769.23920136.86910-0.983104.137303.47260HepG2TAF15
THAP7ENSG00000184436.796.6782050.932900.924502.792901.79290HepG2TFIP11
THAP7ENSG00000184436.7149.2039070.504801.081405.339304.69130HepG2TIAL1
THAP7ENSG00000184436.7133.5466071.128300.908704.109303.44970HepG2TRIM56
THAP7ENSG00000184436.7214.9298087.134501.302409.071407.32010HepG2TUFM
THAP7ENSG00000184436.7183.4455092.233600.991902.630301.81330HepG2UBE2L3
THAP7ENSG00000184436.7124.4345044.888701.470906.980505.76480HepG2UCHL5
THAP7ENSG00000184436.7161.0854069.576701.211004.224602.96880HepG2UPF2
THAP7ENSG00000184436.7349.64680222.902000.649404.937804.17730HepG2UTP3
THAP7ENSG00000184436.794.0717045.119501.059902.710401.62820HepG2XPO5
THAP7ENSG00000184436.7205.2794074.806301.456307.739106.53890HepG2XRN2
THAP7ENSG00000184436.71055.355301593.29550-0.5943011.4254010.36630K562AGGF1
THAP7ENSG00000184436.7968.177101657.88780-0.7760011.9155010.43020K562AKAP8L
THAP7ENSG00000184436.73243.523102320.882300.482806.248304.26570K562APOBEC3C
THAP7ENSG00000184436.72488.068101887.299100.398601.994201.48090K562AQR
THAP7ENSG00000184436.71110.54660772.567000.523402.514601.60190K562BCLAF1
THAP7ENSG00000184436.71631.770201054.508500.629807.165305.27230K562CCAR1
THAP7ENSG00000184436.71371.074601771.86110-0.370003.977902.15180K562CEBPZ
THAP7ENSG00000184436.72458.598803233.77190-0.395404.299103.07370K562CELF1
THAP7ENSG00000184436.73162.320502469.309200.356806.335105.40700K562DDX47
THAP7ENSG00000184436.71097.57370649.212800.757505.736304.39220K562EFTUD2
THAP7ENSG00000184436.71468.427501072.575000.453102.382101.45470K562EIF3A
THAP7ENSG00000184436.7550.56710312.496300.817009.752108.25470K562EIF3G
THAP7ENSG00000184436.71094.36520640.362400.773002.077601.36200K562EIF4A3
THAP7ENSG00000184436.7850.03670576.605600.559802.629601.51610K562EIF4B
THAP7ENSG00000184436.72114.543601725.388500.293302.350101.56870K562FIP1L1
THAP7ENSG00000184436.7676.283701015.15070-0.586005.088603.48120K562FKBP4
THAP7ENSG00000184436.71382.50600665.936401.0537011.5953010.44350K562FXR1
THAP7ENSG00000184436.769.32110193.09810-1.478008.654007.26000K562G3BP2
THAP7ENSG00000184436.73669.660602347.528800.644405.056004.03330K562GRSF1
THAP7ENSG00000184436.71783.469201419.266700.329402.180501.35730K562HNRNPM
THAP7ENSG00000184436.7605.89920344.686100.813702.500001.54080K562IGF2BP2
THAP7ENSG00000184436.7507.69530350.477900.534504.017702.52330K562IGF2BP3
THAP7ENSG00000184436.71134.567401759.46260-0.633005.307604.08780K562KIF1C
THAP7ENSG00000184436.7723.75270981.58740-0.439602.136501.32830K562KRR1
THAP7ENSG00000184436.7867.02940361.968201.2601023.3960020.74510K562MAGOH
THAP7ENSG00000184436.7801.98310361.190701.150703.491102.43940K562MATR3
THAP7ENSG00000184436.71504.485801122.082200.423004.262403.15970K562METAP2
THAP7ENSG00000184436.7791.318701381.55260-0.804003.642302.59730K562NAA15
THAP7ENSG00000184436.71989.072902438.97810-0.294205.652304.64150K562NSUN2
THAP7ENSG00000184436.71548.312101150.976400.427703.132101.58870K562NUSAP1
THAP7ENSG00000184436.72529.011301958.816000.368502.779301.95680K562PPIG
THAP7ENSG00000184436.71122.07930631.767300.828603.377102.54580K562PRPF8
THAP7ENSG00000184436.71384.254401047.981100.401402.709101.81560K562PSIP1
THAP7ENSG00000184436.7966.78150351.695901.4588033.3896031.17080K562PTBP1
THAP7ENSG00000184436.72518.733503052.22490-0.277202.573701.54590K562PUM1
THAP7ENSG00000184436.7749.558301644.22960-1.1333020.7663019.31040K562PUS1
THAP7ENSG00000184436.71108.140001602.00450-0.531707.941606.96820K562RBM15
THAP7ENSG00000184436.7756.81400337.079601.166707.126505.70090K562RBM22
THAP7ENSG00000184436.7599.81770328.706800.867607.901205.31350K562RBM34
THAP7ENSG00000184436.71315.71830956.308900.460204.970903.64020K562RCC2
THAP7ENSG00000184436.7575.68290354.758500.698304.022702.67100K562NELFE
THAP7ENSG00000184436.71069.30840643.284900.733005.029203.92460K562RPS19
THAP7ENSG00000184436.7841.85970450.849700.900807.819706.02250K562RPS3
THAP7ENSG00000184436.72186.074401259.587200.795303.151401.99540K562SAFB
THAP7ENSG00000184436.7705.387301127.98450-0.677302.487501.37230K562SF1
THAP7ENSG00000184436.71918.868302406.53420-0.326704.123403.13970K562SF3A3
THAP7ENSG00000184436.7396.02290200.931800.9788010.345308.64190K562SF3B4
THAP7ENSG00000184436.7788.826601294.97660-0.715103.014201.71260K562SNRNP200
THAP7ENSG00000184436.71355.14810906.538500.579906.523104.75540K562SRFBP1
THAP7ENSG00000184436.7970.48730631.181100.620603.123401.37790K562SRP68
THAP7ENSG00000184436.71972.392702465.53590-0.322002.952201.99010K562SRPK2
THAP7ENSG00000184436.7889.40930344.811101.3669013.7795012.19960K562SRSF1
THAP7ENSG00000184436.7734.40790435.142800.755005.972004.31870K562SRSF4
THAP7ENSG00000184436.7597.55200325.726800.875304.685403.25470K562SRSF5
THAP7ENSG00000184436.71637.252202263.65680-0.467404.710602.88540K562SSRP1
THAP7ENSG00000184436.7839.227201589.14830-0.921103.459701.33980K562SUGP2
THAP7ENSG00000184436.72013.487601417.723900.506003.305302.40830K562SYNCRIP
THAP7ENSG00000184436.7106.18620189.56060-0.836102.894401.38630K562TAF15
THAP7ENSG00000184436.71006.93080348.902701.5290010.791709.23750K562TARDBP
THAP7ENSG00000184436.7720.43380336.574101.0978016.7622014.61400K562TIA1
THAP7ENSG00000184436.7586.41510330.441600.827408.068205.93790K562TRA2A
THAP7ENSG00000184436.71353.773801071.010900.337902.774801.82720K562TRIM56
THAP7ENSG00000184436.71498.050602212.84890-0.562805.930904.62350K562WDR3
THAP7ENSG00000184436.71227.13440659.325000.896107.775305.45730K562XRN2
THAP7ENSG00000184436.7851.524701524.30990-0.840004.093101.97810K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for THAP7 is not available on ENCORE database.





19 RBPs can affect the splicing of THAP7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSTHAP7ENSG00000184436.7chr22-2135456021354801213545602135472121354935213550640.071000.000000.00000longerK562AQR
A3SSTHAP7ENSG00000184436.7chr22-2135493521355102213549352135507621355544213557000.173000.000000.00000longerK562AQR
A5SSTHAP7ENSG00000184436.7chr22-213559952135620021356120213562002135493521355700-0.225000.000040.01192shorterK562TARDBP
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.068000.000000.00040includedHepG2SFPQ
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.431000.000000.00000includedK562SF3B4
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.131000.005400.07843includedHepG2PCBP2
RITHAP7ENSG00000184436.7chr22-2135493521356084213549352135570021355995213560840.167000.016020.08410includedK562PUS1
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.088000.000010.00157includedK562HNRNPU
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.052000.000060.00073includedHepG2U2AF2
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.098000.000100.02433includedK562IGF2BP2
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.121000.000000.00011includedK562SRSF1
RITHAP7ENSG00000184436.7chr22-2135493521356084213549352135570021355995213560840.165000.001410.03183includedK562SRSF1
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.133000.000000.00123includedK562HNRNPK
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.092000.000160.05202includedHepG2HNRNPM
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.071000.001300.01792includedK562PRPF8
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.081000.000540.01551includedK562RBM22
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.126000.000000.00002includedHepG2U2AF1
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.157000.000000.00010includedK562U2AF1
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.233000.000000.00000includedK562U2AF2
RITHAP7ENSG00000184436.7chr22-213549352135608421354935213557002135599521356084-0.105000.001950.07995excludedK562SBDS
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.059000.000220.03115includedK562ZC3H8
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.190000.001050.00970includedHepG2SF3B4
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.114000.000000.00003includedK562EFTUD2
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.341000.000000.00000includedK562AQR
RITHAP7ENSG00000184436.7chr22-2135493521356084213549352135570021355995213560840.218000.000010.00075includedK562TARDBP
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.153000.000000.00000includedK562TARDBP
RITHAP7ENSG00000184436.7chr22-2135493521356084213549352135570021355995213560840.147000.007040.09243includedK562PTBP1
RITHAP7ENSG00000184436.7chr22-2135493521355700213549352135507621355544213557000.075000.001160.02432includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for THAP7 is not avaliable on ENCORE database.