TERF2

General Information

Gene Name : TERF2
Gene ID : ENSG00000132604.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: TERF2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	TERF2	ENSG00000132604.10	28.49	32.31	30.40	ENCSR000AEF
HepG2	TERF2	ENSG00000132604.10	21.32	37.59	29.46	ENCSR985KAT
K562	TERF2	ENSG00000132604.10	31.83	38.10	34.97	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for TERF2 is not avaliable on ENCORE database.

Proteins bound to RNA

TERF2 RNA is bound by 20 proteins.

eCLIP assay for TERF2 is not avaliable on ENCORE database.

20 proteins are bound to TERF2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	69419343	69419403	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.09718	6.74224	HepG2	AQR
chr16	69402232	69402335	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.98607	6.04760	K562	AQR
chr16	69390123	69390207	-	3'-UTR,5'-UTR,intron-Distal,intron-Proximal	3.11558	6.46691	K562	UPF1
chr16	69419330	69419404	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.44095	8.16546	K562	BUD13
chr16	69419341	69419401	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.47028	3.32861	HepG2	U2AF2
chr16	69402294	69402366	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.25864	4.99842	HepG2	PPIG
chr16	69419346	69419452	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.13191	16.14488	HepG2	EFTUD2
chr16	69404339	69404421	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.90490	8.70001	HepG2	PRPF8
chr16	69400533	69400616	-	3'-UTR,intron-Distal,intron-Proximal	4.22463	3.15006	K562	RBM15
chr16	69419319	69419457	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.04532	9.01522	HepG2	BUD13
chr16	69389742	69389833	-	3'-UTR,intron-Distal	4.36851	7.33240	HepG2	PCBP2
chr16	69390110	69390194	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.50039	9.14684	K562	FAM120A
chr16	69419337	69419453	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.68137	10.82062	K562	AQR
chr16	69400940	69401049	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.54776	3.81597	K562	RBM15
chr16	69419335	69419403	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.32407	8.18981	HepG2	PRPF8
chr16	69402379	69402422	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.95318	3.02181	K562	PRPF8
chr16	69389754	69389830	-	3'-UTR,intron-Distal	4.32668	4.58231	HepG2	HNRNPK
chr16	69419354	69419451	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.37108	6.83858	K562	GTF2F1
chr16	69402278	69402350	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.57080	4.06757	K562	UCHL5
chr16	69404340	69404364	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.03584	6.04760	K562	AQR
chr16	69419656	69419788	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.37702	14.13897	HepG2	GTF2F1
chr16	69419403	69419502	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.65911	9.23918	HepG2	PRPF8
chr16	69419396	69419469	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.39678	9.55950	HepG2	PRPF4
chr16	69419403	69419477	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.70615	10.32702	HepG2	AQR
chr16	69419586	69419773	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.33200	10.68100	HepG2	PCBP2
chr16	69419684	69419787	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.03044	21.62907	HepG2	PRPF4
chr16	69419406	69419466	-	5'-UTR,intron-Distal,intron-Proximal	3.75505	7.09278	HepG2	PPIG
chr16	69418562	69418643	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.46766	5.75231	K562	AQR
chr16	69419410	69419473	-	5'-UTR,intron-Distal,intron-Proximal	4.24937	4.14518	HepG2	GTF2F1
chr16	69418481	69418536	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.18988	3.01428	K562	UCHL5
chr16	69419394	69419456	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.28052	10.27121	K562	EFTUD2
chr16	69418492	69418619	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.18809	3.49055	K562	GRWD1
chr16	69419584	69419674	-	CDS,intron-Distal,intron-Proximal	3.63206	7.91299	K562	GTF2F1
chr16	69400858	69400919	-	CDS,intron-Distal,intron-Proximal	3.03183	4.61701	K562	ZNF622
chr16	69419662	69419735	-	CDS,intron-Distal,intron-Proximal	3.40984	3.12941	K562	UCHL5
chr16	69419599	69419650	-	CDS,intron-Distal,intron-Proximal	4.06252	5.28523	K562	DDX51
chr16	69400882	69400917	-	CDS,intron-Distal,intron-Proximal	4.04345	3.16051	HepG2	PPIG
chr16	69400642	69400682	-	CDS,intron-Distal,intron-Proximal	4.46497	4.34093	HepG2	RBM15
chr16	69419593	69419677	-	CDS,intron-Distal,intron-Proximal	3.44273	9.61680	HepG2	PRPF4
chr16	69400858	69400946	-	CDS,intron-Distal,intron-Proximal	3.44233	5.14253	HepG2	GRWD1
chr16	69419594	69419656	-	CDS,intron-Distal,intron-Proximal	3.42381	6.40042	HepG2	GTF2F1
chr16	69419581	69419629	-	CDS,intron-Distal,intron-Proximal	3.90971	3.09880	K562	DROSHA
chr16	69404364	69404386	-	CDS,intron-Distal,intron-Proximal	3.89579	4.52312	K562	AQR
chr16	69404788	69404887	-	intron-Distal	3.33864	4.00486	HepG2	HNRNPL
chr16	69418393	69418456	-	intron-Distal,intron-Proximal	4.02158	3.88726	HepG2	TIAL1
chr16	69419189	69419289	-	intron-Distal,intron-Proximal	5.04298	7.79404	K562	PRPF8
chr16	69418385	69418453	-	intron-Distal,intron-Proximal	3.02918	3.49653	K562	PRPF8
chr16	69419193	69419293	-	intron-Distal,intron-Proximal	6.61955	14.81397	K562	AQR
chr16	69419241	69419292	-	intron-Distal,intron-Proximal	4.86172	6.38747	HepG2	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for TERF2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for TERF2 is not available on ENCORE database.
49 RBPs can affect the levels of TERF2.

The Knockdown/knockout RNA-Seq assay for TERF2 is not available on ENCORE database.

49 RBPs can affect the gene expression of TERF2 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TERF2	ENSG00000132604.6	1350.65590	778.50810	0.79480	7.89710	7.04910	HepG2	AKAP1
TERF2	ENSG00000132604.6	843.97150	644.16080	0.38970	2.43580	1.69400	HepG2	ASCC1
TERF2	ENSG00000132604.6	787.17070	576.35040	0.44960	5.46820	4.59300	HepG2	CKAP4
TERF2	ENSG00000132604.6	680.63330	491.00590	0.47100	3.76250	2.52620	HepG2	EIF3G
TERF2	ENSG00000132604.6	1011.80470	680.62450	0.57190	4.45360	3.64600	HepG2	EIF4A3
TERF2	ENSG00000132604.6	621.59990	804.78150	-0.37260	2.52450	1.74480	HepG2	EIF4G2
TERF2	ENSG00000132604.6	918.20580	676.20640	0.44130	3.12700	2.18060	HepG2	G3BP2
TERF2	ENSG00000132604.6	954.10420	644.92660	0.56490	5.03700	4.11510	HepG2	HNRNPK
TERF2	ENSG00000132604.6	1057.99840	686.88210	0.62310	5.64820	4.72210	HepG2	MAGOH
TERF2	ENSG00000132604.6	1037.71350	690.73930	0.58710	4.55370	3.76190	HepG2	MATR3
TERF2	ENSG00000132604.6	915.88280	766.93360	0.25600	2.12760	1.44170	HepG2	PRPF4
TERF2	ENSG00000132604.6	1038.65140	855.67350	0.27950	2.88530	2.28290	HepG2	PUM1
TERF2	ENSG00000132604.6	765.65670	587.18140	0.38280	3.96390	3.25160	HepG2	PUS1
TERF2	ENSG00000132604.6	1150.67620	826.88780	0.47660	5.20040	4.07060	HepG2	RBM15
TERF2	ENSG00000132604.6	1047.75440	729.68080	0.52190	6.64000	5.86300	HepG2	NELFE
TERF2	ENSG00000132604.6	825.45600	679.57310	0.28050	2.14230	1.59080	HepG2	RECQL
TERF2	ENSG00000132604.6	688.52700	465.01580	0.56610	5.03450	4.23270	HepG2	RPS19
TERF2	ENSG00000132604.6	731.58010	566.04120	0.37000	2.07650	1.37720	HepG2	RPS2
TERF2	ENSG00000132604.6	459.62990	566.62340	-0.30190	2.18490	1.60060	HepG2	SAFB2
TERF2	ENSG00000132604.6	1241.08720	856.70660	0.53460	3.50430	2.74190	HepG2	SF3A3
TERF2	ENSG00000132604.6	931.80680	712.51430	0.38700	3.95950	3.41920	HepG2	SRSF1
TERF2	ENSG00000132604.6	1144.67640	917.65150	0.31880	3.51230	2.95010	HepG2	SSB
TERF2	ENSG00000132604.6	1132.18810	905.14090	0.32280	3.57030	2.88050	HepG2	SUCLG1
TERF2	ENSG00000132604.6	493.10320	623.78290	-0.33920	2.88660	2.31360	HepG2	TRIM56
TERF2	ENSG00000132604.6	1092.90530	734.32360	0.57360	5.39290	4.53190	HepG2	U2AF1
TERF2	ENSG00000132604.6	635.36800	759.76950	-0.25800	2.07190	1.45240	HepG2	UPF1
TERF2	ENSG00000132604.6	1135.68900	733.52490	0.63050	11.07270	10.00300	HepG2	UTP3
TERF2	ENSG00000132604.6	907.91280	706.20710	0.36240	2.64290	1.49310	K562	AARS
TERF2	ENSG00000132604.6	791.17030	1014.05140	-0.35810	3.72960	3.08880	K562	AGGF1
TERF2	ENSG00000132604.6	828.47920	1055.15590	-0.34890	2.61910	1.98260	K562	AKAP8L
TERF2	ENSG00000132604.6	1741.98050	1183.73610	0.55730	5.66020	4.87200	K562	AQR
TERF2	ENSG00000132604.6	2356.90720	1373.29280	0.77920	19.06140	17.50140	K562	DDX47
TERF2	ENSG00000132604.6	866.82000	1143.18120	-0.39920	4.47160	3.58460	K562	EIF2S2
TERF2	ENSG00000132604.6	776.45320	555.82550	0.48220	2.27190	1.37030	K562	EIF3A
TERF2	ENSG00000132604.6	702.14220	544.95410	0.36550	2.88610	2.07480	K562	EIF3G
TERF2	ENSG00000132604.6	814.77820	497.84390	0.71060	7.77850	6.40200	K562	EIF4A3
TERF2	ENSG00000132604.6	958.88380	517.73450	0.88900	16.06080	14.71010	K562	FXR1
TERF2	ENSG00000132604.6	1266.11020	1523.51020	-0.26700	1.94330	1.30360	K562	GRSF1
TERF2	ENSG00000132604.6	927.21740	674.31680	0.45940	3.32240	1.95420	K562	HNRNPK
TERF2	ENSG00000132604.6	1636.12560	1240.98950	0.39870	4.06350	2.75440	K562	HNRNPL
TERF2	ENSG00000132604.6	727.63990	937.04060	-0.36490	2.97650	2.05010	K562	HNRNPU
TERF2	ENSG00000132604.6	813.74170	1071.91440	-0.39750	2.98730	1.86050	K562	MAK16
TERF2	ENSG00000132604.6	862.32770	1065.45310	-0.30520	3.07690	2.22660	K562	MTPAP
TERF2	ENSG00000132604.6	820.73160	631.36000	0.37830	2.63500	1.68080	K562	PCBP2
TERF2	ENSG00000132604.6	1251.37480	991.20560	0.33620	3.12980	2.27470	K562	POLR2G
TERF2	ENSG00000132604.6	817.53370	636.14890	0.36180	2.22260	1.54640	K562	PRPF8
TERF2	ENSG00000132604.6	907.25190	689.50440	0.39580	3.43830	2.70750	K562	PTBP1
TERF2	ENSG00000132604.6	753.02490	1046.50080	-0.47480	4.00020	3.36500	K562	PUS1
TERF2	ENSG00000132604.6	827.08580	660.96780	0.32340	2.09650	1.36980	K562	RBM22
TERF2	ENSG00000132604.6	915.92060	695.60610	0.39690	2.82930	1.72340	K562	NELFE
TERF2	ENSG00000132604.6	1147.47040	647.98370	0.82430	8.60100	7.14600	K562	RPS19
TERF2	ENSG00000132604.6	861.47200	563.10800	0.61330	4.82980	3.45990	K562	RPS3
TERF2	ENSG00000132604.6	665.86470	503.39480	0.40340	3.27890	2.34650	K562	SF3B4
TERF2	ENSG00000132604.6	834.15860	675.98220	0.30320	2.06560	1.44420	K562	SRSF1
TERF2	ENSG00000132604.6	1309.92710	994.21260	0.39780	4.16950	3.15550	K562	SYNCRIP
TERF2	ENSG00000132604.6	1393.01920	1116.88930	0.31860	4.24270	3.21030	K562	WDR43
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for TERF2 is not available on ENCORE database.

11 RBPs can affect the splicing of TERF2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	TERF2	ENSG00000132604.6	chr16	-	69402489	69402498	69402278	69402385	69404385	69404469	-0.17100	0.00177	0.02288	excluded	HepG2	U2AF2
SE	TERF2	ENSG00000132604.6	chr16	-	69404385	69404532	69402278	69402385	69418482	69418613	-0.30900	0.00001	0.00015	excluded	K562	AQR
SE	TERF2	ENSG00000132604.6	chr16	-	69402489	69402498	69402278	69402385	69404385	69404532	0.31500	0.00001	0.00108	included	HepG2	SRSF9
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.21800	0.00004	0.00631	longer	K562	AGGF1
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.22100	0.00012	0.03856	longer	HepG2	HNRNPU
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.18800	0.00000	0.00011	longer	K562	HNRNPU
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	-0.10000	0.00067	0.05666	shorter	HepG2	HNRNPK
A3SS	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69404385	69404532	-0.14600	0.00002	0.00342	shorter	HepG2	HNRNPK
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.14100	0.00054	0.04952	longer	K562	AKAP8L
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	-0.08900	0.00037	0.04629	shorter	K562	FXR1
A3SS	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69404385	69404532	-0.17500	0.00001	0.00039	shorter	HepG2	U2AF2
A3SS	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69404385	69404532	0.14300	0.00032	0.00252	longer	K562	AQR
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.09300	0.00040	0.00304	longer	K562	AQR
A3SS	TERF2	ENSG00000132604.6	chr16	-	69406171	69406357	69406171	69406258	69418482	69418613	0.13000	0.00000	0.00000	longer	K562	AQR
A3SS	TERF2	ENSG00000132604.6	chr16	-	69391420	69391558	69391420	69391464	69395306	69395436	0.10700	0.00812	0.04421	longer	K562	AQR
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.22300	0.00003	0.00210	longer	K562	PUS1
A3SS	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69404385	69404532	-0.10100	0.00111	0.04360	shorter	HepG2	U2AF1
A3SS	TERF2	ENSG00000132604.6	chr16	-	69404436	69404647	69404436	69404532	69406171	69406258	0.18800	0.00003	0.00557	longer	K562	RBM15
A3SS	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69404385	69404532	0.23200	0.00004	0.02003	longer	HepG2	SRSF9
RI	TERF2	ENSG00000132604.6	chr16	-	69402278	69402498	69402278	69402385	69402489	69402498	0.49800	0.00287	0.01921	included	K562	PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

TERF2

General Information

Functions

Localization

Domains (AlphaFold: TERF2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for TERF2 is not avaliable on ENCORE database.

20 proteins are bound to TERF2 RNA:

eCLIP assay for TERF2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for TERF2 is not available on ENCORE database.

49 RBPs can affect the gene expression of TERF2 :

The Knockdown/knockout RNA-Seq assay for TERF2 is not available on ENCORE database.

11 RBPs can affect the splicing of TERF2 :

The Knockdown/knockout RNA-Seq assay for TERF2 is not avaliable on ENCORE database.