SOS1

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SOS1	ENSG00000115904.12	14.91	11.17	13.04	ENCSR000AEF
HepG2	SOS1	ENSG00000115904.12	14.88	25.83	20.36	ENCSR985KAT
K562	SOS1	ENSG00000115904.12	17.67	18.04	17.86	ENCSR000AEO

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SOS1 is not avaliable on ENCORE database.

Proteins bound to RNA

SOS1 RNA is bound by 41 proteins.

eCLIP assay for SOS1 is not avaliable on ENCORE database.

41 proteins are bound to SOS1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	39211888	39211932	-	3'-UTR,intron-Distal	5.36427	7.24744	K562	PUM2
chr2	39251235	39251295	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.01274	6.94932	HepG2	TRA2A
chr2	39294768	39294812	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.18227	12.39807	HepG2	BCLAF1
chr2	39251215	39251279	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.29295	33.68898	HepG2	BCLAF1
chr2	39250181	39250296	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.00577	76.29687	HepG2	BCLAF1
chr2	39250234	39250299	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.45963	4.33023	K562	ZNF622
chr2	39208901	39208994	-	3'-UTR,intron-Distal	4.20534	10.43204	HepG2	FUBP3
chr2	39251175	39251240	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.20210	3.77023	K562	ZNF622
chr2	39212734	39212802	-	3'-UTR,intron-Distal,intron-Proximal	5.11676	10.24308	K562	PUM2
chr2	39251150	39251215	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.14036	30.69011	HepG2	BCLAF1
chr2	39211932	39211987	-	3'-UTR,intron-Distal	6.38506	9.84608	K562	PUM2
chr2	39294857	39294918	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.85272	5.93727	K562	SF3B4
chr2	39212899	39212965	-	3'-UTR,intron-Distal	5.01247	10.53917	K562	PUM2
chr2	39251221	39251287	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.47171	3.50696	K562	BUD13
chr2	39294857	39294903	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.30284	9.28362	K562	U2AF2
chr2	39250355	39250364	-	3'-UTR,CDS,intron-Distal	5.74259	10.47286	HepG2	BCLAF1
chr2	39211736	39211815	-	3'-UTR,intron-Distal	3.43646	9.59322	HepG2	CSTF2
chr2	39208875	39208998	-	3'-UTR,intron-Distal	7.35472	13.67942	K562	PUM2
chr2	39347549	39347644	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.68959	10.52364	K562	GEMIN5
chr2	39348111	39348149	-	5'-UTR,intron-Distal	3.10527	7.91814	HepG2	DDX3X
chr2	39239459	39239487	-	CDS,intron-Distal	4.07751	12.50436	HepG2	BCLAF1
chr2	39222479	39222501	-	CDS,intron-Distal	3.48217	7.42278	HepG2	BCLAF1
chr2	39249761	39249804	-	CDS,intron-Distal	3.42459	11.44176	HepG2	BCLAF1
chr2	39240652	39240704	-	CDS,intron-Distal	4.52505	23.50934	HepG2	BCLAF1
chr2	39234174	39234240	-	CDS,intron-Distal	4.14465	17.73829	HepG2	BCLAF1
chr2	39249944	39250001	-	CDS,intron-Distal,intron-Proximal	4.37282	15.55920	HepG2	BCLAF1
chr2	39216386	39216476	-	CDS,intron-Distal,intron-Proximal	3.30581	13.31748	HepG2	U2AF2
chr2	39250129	39250242	-	CDS,intron-Distal,intron-Proximal	3.03787	6.07026	HepG2	GRWD1
chr2	39224549	39224566	-	CDS,intron-Distal	4.75266	15.55279	HepG2	BCLAF1
chr2	39262494	39262538	-	CDS,intron-Distal,intron-Proximal	4.50077	20.02267	HepG2	PRPF8
chr2	39213156	39213223	-	CDS,intron-Distal,intron-Proximal	5.15462	14.23629	HepG2	PCBP2
chr2	39213282	39213364	-	CDS,intron-Distal	3.61245	4.60014	HepG2	IGF2BP1
chr2	39233552	39233586	-	CDS,intron-Distal,intron-Proximal	4.81043	26.88857	HepG2	BCLAF1
chr2	39262533	39262585	-	CDS,intron-Distal,intron-Proximal	4.13808	18.57216	HepG2	BCLAF1
chr2	39237803	39237845	-	CDS,intron-Distal,intron-Proximal	3.80181	18.97241	HepG2	BCLAF1
chr2	39241006	39241046	-	CDS,intron-Distal,intron-Proximal	4.59311	22.71888	HepG2	BCLAF1
chr2	39281838	39281911	-	CDS,intron-Distal	3.95349	19.83693	HepG2	BCLAF1
chr2	39224464	39224480	-	CDS,intron-Distal,intron-Proximal	3.87282	6.97808	HepG2	BCLAF1
chr2	39222269	39222313	-	CDS,intron-Distal	3.90111	12.83484	HepG2	BCLAF1
chr2	39224493	39224567	-	CDS,intron-Distal,intron-Proximal	4.60486	4.56100	HepG2	FXR2
chr2	39285871	39285926	-	CDS,intron-Distal	3.07905	12.39807	HepG2	BCLAF1
chr2	39250222	39250285	-	CDS,intron-Distal,intron-Proximal	3.65085	4.49790	HepG2	AGGF1
chr2	39250113	39250162	-	CDS,intron-Distal	3.91485	12.01397	HepG2	BCLAF1
chr2	39237730	39237803	-	CDS,intron-Distal	3.77846	22.36185	HepG2	BCLAF1
chr2	39262369	39262403	-	CDS,intron-Distal	4.02079	11.64153	HepG2	BCLAF1
chr2	39233649	39233670	-	CDS,intron-Distal	3.47810	8.57930	HepG2	BCLAF1
chr2	39233629	39233649	-	CDS,intron-Distal	3.13070	10.90260	HepG2	BCLAF1
chr2	39213364	39213440	-	CDS,intron-Distal	4.38176	4.94157	HepG2	IGF2BP1
chr2	39241904	39241958	-	CDS,intron-Distal,intron-Proximal	5.14318	21.42363	HepG2	BCLAF1
chr2	39224397	39224417	-	CDS,intron-Distal,intron-Proximal	4.49538	10.24470	HepG2	BCLAF1
chr2	39234295	39234315	-	CDS,intron-Distal	4.47102	8.41475	HepG2	BCLAF1
chr2	39281928	39281964	-	CDS,intron-Distal	4.98402	16.44959	HepG2	BCLAF1
chr2	39241046	39241080	-	CDS,intron-Distal	4.67666	13.76815	HepG2	BCLAF1
chr2	39262495	39262544	-	CDS,intron-Distal,intron-Proximal	3.47471	4.06013	K562	PRPF8
chr2	39214703	39214749	-	CDS,intron-Distal,intron-Proximal	3.52538	5.36861	HepG2	U2AF2
chr2	39239424	39239459	-	CDS,intron-Distal	4.69153	13.85602	HepG2	BCLAF1
chr2	39241098	39241130	-	CDS,intron-Distal	3.97538	14.30125	HepG2	BCLAF1
chr2	39262316	39262361	-	CDS,intron-Distal,intron-Proximal	5.14761	5.01842	HepG2	PRPF8
chr2	39234170	39234231	-	CDS,intron-Distal,intron-Proximal	3.28373	4.89854	HepG2	ZNF800
chr2	39347461	39347542	-	CDS,intron-Distal,intron-Proximal	3.26875	8.07998	HepG2	PPIG
chr2	39262352	39262369	-	CDS,intron-Distal,intron-Proximal	4.56002	13.32408	HepG2	BCLAF1
chr2	39250178	39250269	-	CDS,intron-Distal,intron-Proximal	3.13998	5.65591	HepG2	ZNF800
chr2	39239298	39239330	-	CDS,intron-Distal	4.22601	13.42460	HepG2	BCLAF1
chr2	39233601	39233629	-	CDS,intron-Distal	3.61207	16.87400	HepG2	BCLAF1
chr2	39233586	39233601	-	CDS,intron-Distal	4.02787	18.52787	HepG2	BCLAF1
chr2	39347482	39347534	-	CDS,intron-Distal	3.24731	3.34231	K562	RBM15
chr2	39285773	39285821	-	CDS,intron-Distal,intron-Proximal	4.10770	4.45914	HepG2	PRPF8
chr2	39285813	39285828	-	CDS,intron-Distal,intron-Proximal	4.79851	17.34901	HepG2	BCLAF1
chr2	39283971	39284007	-	CDS,intron-Distal	3.97154	12.83484	HepG2	BCLAF1
chr2	39283876	39283929	-	CDS,intron-Distal	5.46159	16.53902	HepG2	BCLAF1
chr2	39249722	39249737	-	CDS,intron-Distal	3.63460	6.60490	HepG2	BCLAF1
chr2	39283842	39283876	-	CDS,intron-Distal,intron-Proximal	5.66851	18.83305	HepG2	BCLAF1
chr2	39224505	39224549	-	CDS,intron-Distal	4.88136	17.79964	HepG2	BCLAF1
chr2	39281748	39281789	-	CDS,intron-Distal,intron-Proximal	3.35979	8.01059	K562	KHSRP
chr2	39239312	39239394	-	CDS,intron-Distal	4.25578	3.71613	K562	UCHL5
chr2	39249897	39249943	-	CDS,intron-Distal,intron-Proximal	4.82955	24.03603	HepG2	BCLAF1
chr2	39224138	39224179	-	CDS,intron-Distal	4.24130	12.50436	HepG2	BCLAF1
chr2	39239266	39239298	-	CDS,intron-Distal,intron-Proximal	3.68496	14.18885	HepG2	BCLAF1
chr2	39285828	39285860	-	CDS,intron-Distal	3.93687	11.46750	HepG2	BCLAF1
chr2	39240604	39240652	-	CDS,intron-Distal	4.60979	14.18756	HepG2	BCLAF1
chr2	39262596	39262652	-	CDS,intron-Distal,intron-Proximal	3.13536	6.18258	HepG2	U2AF2
chr2	39249804	39249867	-	CDS,intron-Distal	4.31005	20.29031	HepG2	BCLAF1
chr2	39250171	39250229	-	CDS,intron-Distal,intron-Proximal	3.68831	4.74268	K562	UCHL5
chr2	39345165	39345231	-	intron-Distal	3.14944	11.31950	HepG2	SUGP2
chr2	39344866	39344951	-	intron-Distal	3.03525	3.72088	HepG2	MATR3
chr2	39320356	39320440	-	intron-Distal	4.12236	4.35360	K562	QKI
chr2	39281674	39281712	-	intron-Distal,intron-Proximal	3.66463	7.74116	HepG2	KHSRP
chr2	39347694	39347768	-	intron-Distal,intron-Proximal	3.77579	14.56930	HepG2	DDX3X
chr2	39331868	39331954	-	intron-Distal	4.65764	5.43661	HepG2	CSTF2
chr2	39309087	39309176	-	intron-Distal	3.89656	3.49011	K562	KHSRP
chr2	39298026	39298075	-	intron-Distal	3.84906	4.59145	HepG2	XPO5
chr2	39346574	39346678	-	intron-Distal	3.15672	3.99165	HepG2	PTBP1
chr2	39345469	39345512	-	intron-Distal	3.61312	8.23930	HepG2	SUGP2
chr2	39281712	39281746	-	intron-Distal,intron-Proximal	4.35870	16.06909	HepG2	KHSRP
chr2	39345312	39345394	-	intron-Distal	3.05928	17.90240	HepG2	SUGP2
chr2	39308256	39308307	-	intron-Distal	3.00120	4.34685	HepG2	HNRNPC
chr2	39301442	39301494	-	intron-Distal	3.79424	3.60940	HepG2	HNRNPC
chr2	39268300	39268431	-	intron-Distal	3.23477	7.50579	HepG2	HLTF
chr2	39320403	39320475	-	intron-Distal	4.18253	8.49659	HepG2	QKI
chr2	39281660	39281748	-	intron-Distal,intron-Proximal	5.07809	35.22016	K562	KHSRP
chr2	39346852	39346890	-	intron-Distal	4.20347	4.48529	K562	TIA1
chr2	39319575	39319640	-	intron-Distal	3.78597	3.21433	HepG2	TAF15
chr2	39300200	39300270	-	intron-Distal	4.54590	4.71620	K562	LSM11
chr2	39345310	39345444	-	intron-Distal	4.29848	10.20032	HepG2	MATR3
chr2	39345628	39345680	-	intron-Distal	3.15042	7.98949	HepG2	SUGP2
chr2	39344951	39345023	-	intron-Distal	4.10470	7.91367	HepG2	MATR3
chr2	39232935	39232996	-	intron-Distal	4.96184	4.90095	K562	PTBP1
chr2	39249532	39249630	-	intron-Distal,intron-Proximal	3.63883	5.32632	HepG2	QKI
chr2	39302184	39302265	-	intron-Distal	4.45255	4.17759	HepG2	QKI
chr2	39346823	39346846	-	intron-Distal	3.78199	5.95946	K562	KHSRP
chr2	39310099	39310168	-	intron-Distal	4.63952	16.38238	HepG2	QKI
chr2	39346151	39346249	-	intron-Distal	3.40435	15.99400	HepG2	SUGP2
chr2	39350757	39350802	-	intron-Distal	5.89947	5.86595	K562	LARP7
chr2	39347942	39347986	-	intron-Distal	3.74252	4.65702	K562	GEMIN5
chr2	39320309	39320403	-	intron-Distal	3.67945	8.19300	HepG2	QKI
chr2	39322855	39322920	-	intron-Distal	4.42087	10.10565	HepG2	QKI
chr2	39282718	39282825	-	intron-Distal	3.30526	4.08064	K562	KHSRP
chr2	39272146	39272167	-	intron-Distal	3.11445	3.51804	HepG2	HNRNPL
chr2	39337111	39337152	-	intron-Distal	5.51672	10.68901	HepG2	HNRNPL
chr2	39313275	39313371	-	intron-Distal	3.60237	4.82148	HepG2	PTBP1
chr2	39346721	39346823	-	intron-Distal	3.30266	7.68575	K562	KHSRP
chr2	39310206	39310258	-	intron-Distal	3.37976	7.33362	HepG2	QKI
chr2	39302185	39302275	-	intron-Distal	3.12422	3.65136	HepG2	HNRNPL
chr2	39223966	39224006	-	intron-Distal,intron-Proximal	3.78045	3.20552	HepG2	KHSRP
chr2	39300296	39300397	-	intron-Distal	3.48797	4.14643	HepG2	KHSRP
chr2	39345307	39345409	-	intron-Distal	4.18923	8.40396	K562	MATR3
chr2	39346733	39346816	-	intron-Distal	3.48360	5.30287	HepG2	SFPQ
chr2	39345537	39345608	-	intron-Distal	3.68110	3.64762	HepG2	QKI
chr2	39306157	39306189	-	intron-Distal	4.31806	5.25941	HepG2	HNRNPC
chr2	39304866	39304947	-	intron-Distal	3.00124	3.46531	K562	KHSRP
chr2	39278483	39278553	-	intron-Distal,intron-Proximal	3.45001	5.14864	K562	KHSRP
chr2	39214387	39214487	-	intron-Distal	3.79664	4.93376	K562	PRPF8
chr2	39337102	39337171	-	intron-Distal	5.19042	10.25190	K562	HNRNPL
chr2	39345098	39345165	-	intron-Distal	4.16706	17.43469	HepG2	SUGP2
chr2	39337072	39337167	-	intron-Distal	4.05690	12.26752	K562	AGGF1
chr2	39272321	39272398	-	intron-Distal	3.93520	3.37631	K562	HNRNPL
chr2	39337317	39337363	-	intron-Distal	3.10453	5.67979	HepG2	HNRNPL
chr2	39306409	39306462	-	intron-Distal	3.95852	3.47043	HepG2	KHSRP
chr2	39220099	39220141	-	intron-Distal,intron-Proximal	3.78788	3.38675	HepG2	ILF3
chr2	39344860	39344931	-	intron-Distal	3.03034	8.11243	HepG2	SUGP2
chr2	39280887	39280978	-	intron-Distal	3.01818	3.51437	HepG2	QKI
chr2	39332509	39332563	-	intron-Distal	3.75533	4.73419	HepG2	ILF3
chr2	39276377	39276502	-	intron-Distal	4.03252	4.16015	K562	SAFB2
chr2	39279898	39279969	-	intron-Distal	3.56553	9.99495	HepG2	U2AF2
chr2	39232952	39233007	-	intron-Distal	5.86235	10.89838	HepG2	PTBP1
chr2	39272315	39272407	-	intron-Distal	5.03431	25.93296	HepG2	HNRNPL
chr2	39344935	39345014	-	intron-Distal	4.92509	6.08412	HepG2	HNRNPM
chr2	39313371	39313448	-	intron-Distal	3.43510	3.71789	HepG2	PTBP1
chr2	39310037	39310099	-	intron-Distal	3.85829	12.85455	HepG2	QKI
chr2	39337615	39337692	-	intron-Distal	4.69409	4.94901	HepG2	HNRNPC
chr2	39280427	39280548	-	intron-Distal	3.11374	5.03870	HepG2	HNRNPL
chr2	39347350	39347417	-	intron-Distal,intron-Proximal	4.37522	10.50922	HepG2	RBM22
chr2	39347232	39347276	-	intron-Distal	3.95968	3.06347	K562	NONO
chr2	39347768	39347879	-	intron-Distal	3.58304	19.04313	HepG2	DDX3X
chr2	39344790	39344945	-	intron-Distal	5.08897	9.11520	K562	MATR3
chr2	39309989	39310037	-	intron-Distal	3.40600	5.01093	HepG2	QKI
chr2	39346453	39346518	-	intron-Distal	3.52983	3.63322	HepG2	MATR3
chr2	39346116	39346151	-	intron-Distal	3.58682	6.79980	HepG2	SUGP2
chr2	39344772	39344866	-	intron-Distal	3.28975	4.69218	HepG2	MATR3
chr2	39337177	39337267	-	intron-Distal	3.38393	23.46218	HepG2	HNRNPL
chr2	39310030	39310158	-	intron-Distal	4.91038	7.30165	K562	QKI
chr2	39306189	39306210	-	intron-Distal	4.26354	5.26580	HepG2	HNRNPC
chr2	39347763	39347849	-	intron-Distal	3.21712	7.54132	K562	GEMIN5
chr2	39342076	39342188	-	intron-Distal	3.56336	4.88774	HepG2	TAF15
chr2	39346608	39346664	-	intron-Distal	3.09421	5.88803	HepG2	SUGP2
chr2	39345809	39345852	-	intron-Distal	3.69993	8.28385	HepG2	SUGP2
chr2	39344931	39345022	-	intron-Distal	3.70412	15.06089	HepG2	SUGP2
chr2	39300485	39300560	-	intron-Distal	4.13130	4.79477	K562	KHSRP
chr2	39344865	39344955	-	intron-Distal	3.74426	5.07626	HepG2	PTBP1
chr2	39347338	39347461	-	intron-Distal,intron-Proximal	3.21315	16.00648	HepG2	EFTUD2
chr2	39337152	39337177	-	intron-Distal	4.08868	7.68255	HepG2	HNRNPL
chr2	39303903	39304056	-	intron-Distal	4.09525	3.83958	HepG2	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SOS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SOS1 is not available on ENCORE database.
102 RBPs can affect the levels of SOS1.

The Knockdown/knockout RNA-Seq assay for SOS1 is not available on ENCORE database.

102 RBPs can affect the gene expression of SOS1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SOS1	ENSG00000115904.8	1955.75320	2824.67560	-0.53040	14.43380	13.27630	HepG2	ACO1
SOS1	ENSG00000115904.8	1962.42180	2435.27660	-0.31150	2.38930	1.46000	HepG2	ADAR
SOS1	ENSG00000115904.8	1768.39370	3934.71930	-1.15380	19.55410	18.27430	HepG2	AKAP1
SOS1	ENSG00000115904.8	2784.61070	4210.01770	-0.59640	3.07880	1.98300	HepG2	AKAP8
SOS1	ENSG00000115904.8	2285.83700	3255.60200	-0.51020	5.29910	4.22940	HepG2	ASCC1
SOS1	ENSG00000115904.8	970.39220	2029.25830	-1.06430	8.77700	7.06670	HepG2	BCCIP
SOS1	ENSG00000115904.8	3733.18280	4957.51370	-0.40920	2.80030	1.81860	HepG2	CCAR1
SOS1	ENSG00000115904.8	2242.73890	2824.06520	-0.33250	6.88620	5.92200	HepG2	CKAP4
SOS1	ENSG00000115904.8	1978.91790	3553.88480	-0.84470	7.22850	5.99600	HepG2	CNOT7
SOS1	ENSG00000115904.8	1947.61250	2980.65590	-0.61390	15.62840	14.34560	HepG2	CELF1
SOS1	ENSG00000115904.8	2058.78870	2612.42180	-0.34360	6.76490	5.54910	HepG2	DDX19B
SOS1	ENSG00000115904.8	2378.10710	3769.06070	-0.66440	8.34910	7.31200	HepG2	DDX3X
SOS1	ENSG00000115904.8	1369.66470	1995.06360	-0.54260	2.81070	2.03200	HepG2	DDX55
SOS1	ENSG00000115904.8	2561.07530	3237.94290	-0.33830	2.27780	1.71200	HepG2	DDX6
SOS1	ENSG00000115904.8	2341.92500	2702.45000	-0.20660	2.38860	1.75180	HepG2	DKC1
SOS1	ENSG00000115904.8	1844.12270	2430.50930	-0.39830	9.13510	8.03130	HepG2	DNAJC2
SOS1	ENSG00000115904.8	2548.60570	3439.53250	-0.43250	3.34180	2.64040	HepG2	EIF4A3
SOS1	ENSG00000115904.8	3930.84120	3028.99080	0.37590	3.45730	2.55460	HepG2	EIF4G2
SOS1	ENSG00000115904.8	2330.33820	2760.21580	-0.24420	2.03970	1.32450	HepG2	EWSR1
SOS1	ENSG00000115904.8	1606.32530	2037.30770	-0.34290	2.69400	1.54460	HepG2	FAM120A
SOS1	ENSG00000115904.8	2124.69590	3864.32350	-0.86300	12.16470	10.71680	HepG2	FIP1L1
SOS1	ENSG00000115904.8	2151.08800	3470.69550	-0.69020	9.22690	8.03130	HepG2	FXR1
SOS1	ENSG00000115904.8	2445.83450	3219.39420	-0.39650	3.13290	2.42670	HepG2	G3BP1
SOS1	ENSG00000115904.8	1479.09860	2029.97100	-0.45670	3.53840	2.51270	HepG2	GEMIN5
SOS1	ENSG00000115904.8	1689.88620	2394.87230	-0.50300	3.12200	2.03920	HepG2	GNB2L1
SOS1	ENSG00000115904.8	2440.63370	3289.68940	-0.43070	2.54970	1.48130	HepG2	GRSF1
SOS1	ENSG00000115904.8	2127.07330	2696.75870	-0.34240	5.63130	4.29270	HepG2	HDGF
SOS1	ENSG00000115904.8	1979.12010	2475.73070	-0.32300	3.08170	2.40370	HepG2	HNRNPA1
SOS1	ENSG00000115904.8	2108.57290	2753.76780	-0.38510	4.00740	3.18340	HepG2	HNRNPC
SOS1	ENSG00000115904.8	2593.67620	2214.77940	0.22770	2.73890	2.02480	HepG2	HNRNPF
SOS1	ENSG00000115904.8	2490.27180	2920.00330	-0.22970	3.44770	2.70300	HepG2	HNRNPL
SOS1	ENSG00000115904.8	1777.42280	2666.28260	-0.58500	9.20820	7.64380	HepG2	HNRNPM
SOS1	ENSG00000115904.8	1943.80360	2735.56330	-0.49300	11.64790	10.47550	HepG2	HNRNPU
SOS1	ENSG00000115904.8	2438.16540	3272.37810	-0.42450	4.05680	3.25380	HepG2	IGF2BP2
SOS1	ENSG00000115904.8	2530.36100	3464.47880	-0.45330	2.78630	1.46020	HepG2	ILF3
SOS1	ENSG00000115904.8	2214.54690	2582.10980	-0.22150	3.34680	2.22580	HepG2	KIF1C
SOS1	ENSG00000115904.8	4107.85490	5233.23990	-0.34930	2.19430	1.46170	HepG2	LARP4
SOS1	ENSG00000115904.8	1587.20670	2345.66780	-0.56350	3.99620	2.62700	HepG2	LARP7
SOS1	ENSG00000115904.8	1409.15950	2463.77430	-0.80600	6.53290	4.71650	HepG2	LIN28B
SOS1	ENSG00000115904.8	2657.82070	3471.90870	-0.38550	3.19040	2.48630	HepG2	MAGOH
SOS1	ENSG00000115904.8	2255.42640	3491.28350	-0.63040	6.76040	5.80890	HepG2	MATR3
SOS1	ENSG00000115904.8	1542.65060	2386.19670	-0.62930	4.22540	2.93750	HepG2	METAP2
SOS1	ENSG00000115904.8	2497.06470	3127.63440	-0.32480	3.30060	2.42090	HepG2	MSI2
SOS1	ENSG00000115904.8	3402.40290	2626.26150	0.37340	3.38160	2.03530	HepG2	NAA15
SOS1	ENSG00000115904.8	2630.83970	3573.47630	-0.44180	3.90040	3.15280	HepG2	NCBP2
SOS1	ENSG00000115904.8	2410.12930	3178.43460	-0.39920	5.28070	4.23360	HepG2	NOL12
SOS1	ENSG00000115904.8	2224.72830	2707.77050	-0.28350	4.08190	3.07510	HepG2	PARN
SOS1	ENSG00000115904.8	2658.29120	3025.42320	-0.18660	2.02910	1.49620	HepG2	PCBP1
SOS1	ENSG00000115904.8	2583.75840	3078.60410	-0.25280	3.44020	2.84430	HepG2	PTBP1
SOS1	ENSG00000115904.8	2280.59070	3033.96800	-0.41180	2.59040	2.01150	HepG2	PUF60
SOS1	ENSG00000115904.8	2352.25690	3220.54340	-0.45330	12.24300	11.18290	HepG2	PUM1
SOS1	ENSG00000115904.8	2796.68700	3218.28270	-0.20260	2.00580	1.42890	HepG2	PUM2
SOS1	ENSG00000115904.8	2419.71410	2877.11580	-0.24980	3.81940	3.11880	HepG2	PUS1
SOS1	ENSG00000115904.8	2546.15060	3144.55500	-0.30450	4.13850	3.53760	HepG2	RBM22
SOS1	ENSG00000115904.8	3954.26190	3025.86590	0.38600	4.93290	4.05640	HepG2	RBM25
SOS1	ENSG00000115904.8	2021.89880	2828.38970	-0.48430	2.88510	1.87180	HepG2	RBM27
SOS1	ENSG00000115904.8	2773.81280	3426.08870	-0.30470	4.77410	4.09830	HepG2	NELFE
SOS1	ENSG00000115904.8	1515.96520	2218.25560	-0.54920	5.15720	4.34760	HepG2	RPS19
SOS1	ENSG00000115904.8	1990.83410	2436.15480	-0.29120	4.78560	3.97800	HepG2	SAFB2
SOS1	ENSG00000115904.8	4611.45520	3371.21550	0.45190	5.42670	4.46320	HepG2	SF3B1
SOS1	ENSG00000115904.8	1928.77580	2840.99290	-0.55870	18.91500	17.46510	HepG2	SMN1
SOS1	ENSG00000115904.8	2860.23200	3345.42010	-0.22610	3.12970	2.63540	HepG2	SRSF1
SOS1	ENSG00000115904.8	2567.93840	2995.42460	-0.22210	3.12150	2.46220	HepG2	SRSF5
SOS1	ENSG00000115904.8	3337.60020	2721.75490	0.29420	5.33100	4.60950	HepG2	SRSF9
SOS1	ENSG00000115904.8	2091.99150	3103.24010	-0.56890	4.69210	3.22370	HepG2	STIP1
SOS1	ENSG00000115904.8	2737.37740	3406.77440	-0.31560	7.06650	6.15260	HepG2	SUCLG1
SOS1	ENSG00000115904.8	3526.16900	3007.24360	0.22960	2.65960	2.10880	HepG2	TAF15
SOS1	ENSG00000115904.8	1654.60760	2658.20440	-0.68400	13.88820	12.91630	HepG2	TIAL1
SOS1	ENSG00000115904.8	1731.30300	2681.86650	-0.63140	17.74630	16.47820	HepG2	TRIM56
SOS1	ENSG00000115904.8	872.68030	1173.46190	-0.42720	2.14050	1.47340	HepG2	UCHL5
SOS1	ENSG00000115904.8	1688.14720	3609.67460	-1.09640	54.74540	52.61230	HepG2	UTP3
SOS1	ENSG00000115904.8	1215.01850	1955.23170	-0.68640	4.59710	3.67130	HepG2	XRN2
SOS1	ENSG00000115904.8	1555.04540	1227.97080	0.34060	2.84610	1.64650	K562	AARS
SOS1	ENSG00000115904.8	4655.43240	3321.09670	0.48720	3.40470	2.02820	K562	ABCF1
SOS1	ENSG00000115904.8	1359.39740	2906.48370	-1.09630	46.90670	44.62850	K562	AGGF1
SOS1	ENSG00000115904.8	885.07980	1126.52350	-0.34800	3.78070	1.99010	K562	AKAP1
SOS1	ENSG00000115904.8	2336.50240	3193.68260	-0.45090	5.41500	3.93280	K562	AKAP8
SOS1	ENSG00000115904.8	1494.61790	3024.30250	-1.01680	21.26920	19.12640	K562	AKAP8L
SOS1	ENSG00000115904.8	2060.49080	3173.17320	-0.62290	14.08730	11.83930	K562	ATP5C1
SOS1	ENSG00000115904.8	3512.39300	2386.97240	0.55720	6.86140	5.46740	K562	BOP1
SOS1	ENSG00000115904.8	4251.27340	3365.43190	0.33700	4.74870	3.45980	K562	CELF1
SOS1	ENSG00000115904.8	953.50770	1209.40430	-0.34300	3.64430	1.55260	K562	DDX24
SOS1	ENSG00000115904.8	1345.93320	1098.31960	0.29320	3.10960	1.69890	K562	DDX27
SOS1	ENSG00000115904.8	3262.06330	2880.70490	0.17930	1.90490	1.34560	K562	DDX47
SOS1	ENSG00000115904.8	914.87370	1157.22270	-0.33900	3.45550	1.95370	K562	DDX6
SOS1	ENSG00000115904.8	1384.55800	956.60210	0.53330	5.09480	3.18210	K562	DHX30
SOS1	ENSG00000115904.8	2355.47620	3254.52600	-0.46640	9.15080	7.36600	K562	DKC1
SOS1	ENSG00000115904.8	1918.10220	1660.53250	0.20790	1.97450	1.34870	K562	EIF2S2
SOS1	ENSG00000115904.8	999.40120	1241.64920	-0.31310	2.97820	2.15170	K562	EIF3G
SOS1	ENSG00000115904.8	3883.84070	2737.38660	0.50460	11.56780	9.70980	K562	EIF4G2
SOS1	ENSG00000115904.8	837.60950	1040.88570	-0.31350	2.60450	1.35620	K562	EWSR1
SOS1	ENSG00000115904.8	1100.52760	2386.92700	-1.11700	6.94210	5.54360	K562	FIP1L1
SOS1	ENSG00000115904.8	1810.16420	1166.32290	0.63410	6.93460	5.01920	K562	FKBP4
SOS1	ENSG00000115904.8	3527.07440	2582.45110	0.44960	4.85450	3.71760	K562	FMR1
SOS1	ENSG00000115904.8	1367.50310	1097.70790	0.31690	3.03840	1.62460	K562	FUS
SOS1	ENSG00000115904.8	1477.47950	1240.11040	0.25260	2.35420	1.78760	K562	FXR1
SOS1	ENSG00000115904.8	1030.07300	1430.60210	-0.47390	5.18700	3.14920	K562	G3BP1
SOS1	ENSG00000115904.8	1796.90330	1270.57550	0.49990	3.52030	2.70220	K562	G3BP2
SOS1	ENSG00000115904.8	1577.98630	2212.88240	-0.48780	6.09490	4.96680	K562	GRSF1
SOS1	ENSG00000115904.8	1951.98190	1494.57000	0.38510	3.07870	1.77100	K562	HNRNPK
SOS1	ENSG00000115904.8	1996.07550	2603.32990	-0.38320	4.26320	2.92280	K562	HNRNPL
SOS1	ENSG00000115904.8	1191.38060	1570.12430	-0.39820	4.98160	3.76840	K562	HNRNPU
SOS1	ENSG00000115904.8	1872.76430	3209.63020	-0.77720	14.70190	12.26630	K562	KIF1C
SOS1	ENSG00000115904.8	2088.12520	3072.33340	-0.55710	6.36260	4.45970	K562	MAK16
SOS1	ENSG00000115904.8	1259.39400	1569.46490	-0.31750	2.82030	1.88850	K562	MATR3
SOS1	ENSG00000115904.8	2874.33200	3595.58410	-0.32300	3.54830	2.49980	K562	MBNL1
SOS1	ENSG00000115904.8	1602.70870	2520.23620	-0.65300	5.93800	4.46670	K562	NAA15
SOS1	ENSG00000115904.8	769.21070	1133.61350	-0.55950	4.83030	2.98400	K562	NONO
SOS1	ENSG00000115904.8	1129.90710	1860.42890	-0.71940	3.71280	2.51800	K562	PABPN1
SOS1	ENSG00000115904.8	1664.62060	2709.32650	-0.70270	3.79130	2.80930	K562	PPIG
SOS1	ENSG00000115904.8	4198.40640	2986.74650	0.49120	6.31540	5.08450	K562	PUF60
SOS1	ENSG00000115904.8	1358.23690	2999.46090	-1.14300	26.26510	24.58650	K562	PUS1
SOS1	ENSG00000115904.8	1347.99370	2922.37140	-1.11630	38.26560	35.97320	K562	RBM15
SOS1	ENSG00000115904.8	1173.76460	1465.18330	-0.31990	2.45850	1.66920	K562	RBM22
SOS1	ENSG00000115904.8	881.82370	1099.18620	-0.31790	2.49480	1.55760	K562	RCC2
SOS1	ENSG00000115904.8	3318.08210	2304.62970	0.52570	3.12230	2.08710	K562	SF3B1
SOS1	ENSG00000115904.8	1483.21920	1140.15460	0.37940	3.44480	1.63530	K562	SND1
SOS1	ENSG00000115904.8	3108.53530	2102.70640	0.56390	17.71470	15.63950	K562	SRPK2
SOS1	ENSG00000115904.8	1106.81790	1414.50040	-0.35390	2.83070	1.76730	K562	SRSF5
SOS1	ENSG00000115904.8	952.00320	1280.77300	-0.42800	5.38110	3.48590	K562	SSB
SOS1	ENSG00000115904.8	1099.51270	1434.79290	-0.38400	3.14480	1.96910	K562	TRA2A
SOS1	ENSG00000115904.8	1801.89120	3040.95600	-0.75500	4.51670	2.71570	K562	UTP18
SOS1	ENSG00000115904.8	2915.77190	2282.50870	0.35320	2.49880	1.36170	K562	UTP3
SOS1	ENSG00000115904.8	2315.26560	1962.40650	0.23850	3.27690	2.36300	K562	WDR43
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SOS1 is not available on ENCORE database.

24 RBPs can affect the splicing of SOS1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.21100	0.00066	0.01485	included	K562	SRSF1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.12900	0.00174	0.03254	included	HepG2	U2AF1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.23300	0.00000	0.00155	included	K562	TROVE2
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	-0.23300	0.00003	0.00647	excluded	HepG2	HNRNPM
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.20200	0.00000	0.00004	included	K562	FMR1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.20800	0.00007	0.00280	included	HepG2	HNRNPK
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.17900	0.00002	0.00352	included	HepG2	TBRG4
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.21700	0.00000	0.00029	included	HepG2	SUGP2
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.25000	0.00004	0.01841	included	HepG2	BCLAF1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	-0.28100	0.00001	0.00086	excluded	HepG2	PTBP1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.16600	0.00004	0.02890	included	HepG2	UPF1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.16800	0.00000	0.00153	included	HepG2	RBM15
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	-0.14400	0.00155	0.04307	excluded	HepG2	SF3A3
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.30300	0.00000	0.00003	included	HepG2	SUPV3L1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.17800	0.00001	0.00284	included	K562	CPSF6
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.19700	0.00005	0.06074	included	HepG2	GTF2F1
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	-0.21000	0.00031	0.06546	excluded	HepG2	XRCC6
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.17700	0.00069	0.04650	included	HepG2	SRSF9
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.23300	0.00000	0.00322	included	HepG2	DROSHA
SE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455			39214613	39214732	39222263	39222528	0.22100	0.00001	0.00268	included	HepG2	KHSRP
A3SS	SOS1	ENSG00000115904.8	chr2	-	39241007	39241162			39241007	39241130	39241905	39242021	0.08200	0.00218	0.01392	longer	K562	AQR
A3SS	SOS1	ENSG00000115904.8	chr2	-	39234171	39234356			39234171	39234334	39237724	39237885	0.23100	0.00000	0.00001	longer	K562	AQR
A3SS	SOS1	ENSG00000115904.8	chr2	-	39285813	39285968			39285813	39285945	39294768	39294894	0.11900	0.00288	0.01778	longer	K562	AQR
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.16400	0.00019	0.00548	2included	HepG2	U2AF1
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	0.21700	0.00001	0.00141	1included	HepG2	PTBP1
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.17700	0.00001	0.00240	2included	HepG2	SUGP2
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.18500	0.00280	0.05655	2included	HepG2	DDX55
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.38500	0.00000	0.00000	2included	HepG2	U2AF2
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.13700	0.00040	0.03050	2included	HepG2	TBRG4
MXE	SOS1	ENSG00000115904.8	chr2	-	39216410	39216455	39222263	39222528	39214613	39214732	39224062	39224179	-0.32600	0.00000	0.00000	2included	HepG2	HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SOS1

General Information

Functions

Localization

Domains (AlphaFold: SOS1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SOS1 is not avaliable on ENCORE database.

41 proteins are bound to SOS1 RNA:

eCLIP assay for SOS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SOS1 is not available on ENCORE database.

102 RBPs can affect the gene expression of SOS1 :

The Knockdown/knockout RNA-Seq assay for SOS1 is not available on ENCORE database.

24 RBPs can affect the splicing of SOS1 :

The Knockdown/knockout RNA-Seq assay for SOS1 is not avaliable on ENCORE database.