RFFL

General Information

Gene Name       : RFFL
Gene ID             : ENSG00000092871.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RFFL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RFFLENSG00000092871.1615.9718.4017.18ENCSR000AEF
HepG2RFFLENSG00000092871.1621.4319.0520.24ENCSR985KAT
K562RFFLENSG00000092871.1610.079.249.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
RFFLRibo-STAMP-293TshRNARFFL-BGRSLV04-47,RFFL-BGRSLV04-48NT-BGRSLV04-1,NT-BGRSLV04-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RFFL is not avaliable on ENCORE database.



Proteins bound to RNA
  • RFFL RNA is bound by 19 proteins.  







eCLIP assay for RFFL is not avaliable on ENCORE database.





19 proteins are bound to RFFL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173333860633338716-3'-UTR,intron-Distal,intron-Proximal3.643493.52299HepG2AKAP1
chr173333828533338382-3'-UTR,intron-Distal,intron-Proximal4.9756429.49816K562UPF1
chr173333794533338031-3'-UTR,intron-Distal4.8894030.43005K562UPF1
chr173333841833338549-3'-UTR,intron-Distal,intron-Proximal3.721435.89157HepG2AKAP1
chr173333771633337762-3'-UTR,intron-Distal4.4308313.10292K562UPF1
chr173333838233338455-3'-UTR,intron-Distal5.5891020.44698K562UPF1
chr173333841433338556-3'-UTR,intron-Distal,intron-Proximal3.570707.40079HepG2UPF1
chr173333791333337945-3'-UTR,intron-Distal5.439179.83131K562UPF1
chr173333617133336308-3'-UTR,intron-Distal6.719999.30499K562PUM2
chr173333795533338030-3'-UTR,intron-Distal3.687266.04577K562FAM120A
chr173335351433353599-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.689975.55825HepG2U2AF2
chr173333645033336505-3'-UTR,intron-Distal3.397645.35486K562UPF1
chr173333795533338040-3'-UTR,intron-Distal4.741585.58306HepG2AKAP1
chr173333845733338616-3'-UTR,intron-Distal,intron-Proximal4.6439225.77479K562UPF1
chr173333782733337862-3'-UTR,intron-Distal4.024728.99604K562UPF1
chr173333822333338249-3'-UTR,intron-Distal4.030925.99105K562UPF1
chr173333855833338683-3'-UTR,intron-Distal,intron-Proximal3.496765.71477HepG2UPF1
chr173333719033337235-3'-UTR,intron-Distal5.4857210.54419K562UPF1
chr173341613133416205-5'-UTR,intron-Distal4.450535.82353HepG2XRN2
chr173334454133344644-CDS,intron-Distal,intron-Proximal4.035694.41267HepG2PPIG
chr173334170633341763-CDS,intron-Distal,intron-Proximal3.895794.00320K562AQR
chr173334336133343471-CDS,intron-Distal,intron-Proximal4.268286.41037HepG2BUD13
chr173334334633343407-CDS,intron-Distal,intron-Proximal3.509747.85990HepG2PRPF8
chr173334170833341813-CDS,intron-Distal,intron-Proximal4.807824.97857HepG2AQR
chr173341597533416015-intron-Distal4.305077.25311HepG2NKRF
chr173340470033404770-intron-Distal4.743036.44072HepG2HNRNPM
chr173337882033378868-intron-Distal3.344863.66782HepG2HNRNPM
chr173337628333376344-intron-Distal4.389614.62276K562TARDBP
chr173341553733415579-intron-Distal3.151343.11000HepG2HNRNPM
chr173338768833387757-intron-Distal4.173694.28663HepG2SUGP2
chr173340926033409338-intron-Distal3.843324.67922K562PTBP1
chr173341601533416089-intron-Distal3.5238410.30254HepG2NKRF
chr173337946433379577-intron-Distal4.455773.55640HepG2QKI
chr173336426933364359-intron-Distal3.199248.93026HepG2QKI
chr173337917733379276-intron-Distal3.424593.76326HepG2RBFOX2
chr173335952933359613-intron-Distal3.034213.02891HepG2HNRNPL
chr173341598433416063-intron-Distal4.9445311.52775HepG2XRN2
chr173336364833363711-intron-Distal4.048176.30359HepG2QKI
chr173340728133407357-intron-Distal4.092613.30440HepG2QKI
chr173340269233402744-intron-Distal3.102144.37623HepG2HNRNPM
chr173340554633405622-intron-Distal3.009063.57155HepG2ILF3
chr173337956733379585-intron-Distal5.162517.79427HepG2PTBP1
chr173335973033359816-intron-Distal4.422344.74221HepG2PTBP1
chr173336459533364669-intron-Distal4.024526.30359HepG2QKI
chr173339955133399614-intron-Distal4.109893.87294K562TARDBP
chr173337990833379961-intron-Distal3.486664.33009HepG2SUGP2
chr173340924733409339-intron-Distal3.9660711.32031HepG2PTBP1
chr173341595233416097-intron-Distal,intron-Proximal5.332838.14499K562XRN2
chr173337841333378454-intron-Distal4.006983.54208HepG2SUGP2
chr173340215733402243-intron-Distal3.982416.98528HepG2HNRNPM
chr173337948233379567-intron-Distal3.995769.41297HepG2PTBP1
chr173334121233341344-intron-Distal3.214333.35377HepG2QKI
chr173337951533379588-intron-Distal4.374823.91475K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RFFL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RFFL is not available on ENCORE database.

  • 114 RBPs can affect the levels of RFFL.  








The Knockdown/knockout RNA-Seq assay for RFFL is not available on ENCORE database.





114 RBPs can affect the gene expression of RFFL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RFFLENSG00000092871.121424.690502057.75160-0.530405.189403.94050HepG2ABCF1
RFFLENSG00000092871.121144.410601419.15020-0.310404.029403.32120HepG2ACO1
RFFLENSG00000092871.12817.474201158.78670-0.503404.455803.22780HepG2ADAR
RFFLENSG00000092871.121430.896902611.21860-0.8678010.805809.82120HepG2AKAP1
RFFLENSG00000092871.121166.174101425.81180-0.290003.247002.42300HepG2AKAP8L
RFFLENSG00000092871.121702.486202160.61140-0.343802.503301.75340HepG2ASCC1
RFFLENSG00000092871.121648.611302031.98650-0.301604.041503.24140HepG2AUH
RFFLENSG00000092871.121316.539301868.56530-0.505203.572802.44990HepG2CCAR1
RFFLENSG00000092871.121045.282101441.76540-0.463902.351101.64950HepG2CNOT7
RFFLENSG00000092871.121118.908501694.30470-0.598608.407806.58610HepG2CPSF7
RFFLENSG00000092871.12925.080201188.32510-0.361303.803102.60500HepG2YBX3
RFFLENSG00000092871.12234.16180564.60500-1.2697016.2696014.03950HepG2CSTF2
RFFLENSG00000092871.121330.172201583.90010-0.251902.431501.82120HepG2CELF1
RFFLENSG00000092871.122142.917201703.022500.331405.973704.94230HepG2DAZAP1
RFFLENSG00000092871.121014.894901312.50730-0.371005.509004.38420HepG2DDX19B
RFFLENSG00000092871.12719.392901109.08290-0.624507.148206.10910HepG2DDX21
RFFLENSG00000092871.121817.747902501.45130-0.460604.043303.29860HepG2DDX3X
RFFLENSG00000092871.12761.158201032.91870-0.440503.681702.12510HepG2DDX52
RFFLENSG00000092871.121888.072901284.373400.555702.813201.82730HepG2DDX59
RFFLENSG00000092871.121508.184802148.55950-0.510604.184903.43710HepG2DDX6
RFFLENSG00000092871.121476.719501125.415300.391803.564102.45840HepG2DHX30
RFFLENSG00000092871.121165.946301357.74030-0.219701.972701.38560HepG2DKC1
RFFLENSG00000092871.121377.131901166.834900.239002.129601.50480HepG2DNAJC21
RFFLENSG00000092871.12793.884201232.51630-0.634606.180004.85360HepG2EEF2
RFFLENSG00000092871.121492.576802065.69950-0.468804.066003.35690HepG2EIF2S1
RFFLENSG00000092871.121250.413901560.75600-0.319802.975701.75790HepG2EIF2S2
RFFLENSG00000092871.12763.957601047.23560-0.455004.562003.21670HepG2EIF3G
RFFLENSG00000092871.121655.860702282.95550-0.463303.548202.82650HepG2EIF4A3
RFFLENSG00000092871.122058.414001680.187000.292803.819902.86540HepG2EIF4G1
RFFLENSG00000092871.121383.590201782.34220-0.365403.232402.05340HepG2ESF1
RFFLENSG00000092871.121663.915802332.96070-0.487609.357008.35910HepG2ETF1
RFFLENSG00000092871.121488.157402077.77270-0.481503.943603.03840HepG2FIP1L1
RFFLENSG00000092871.12777.390801348.70850-0.794906.707705.03240HepG2FUS
RFFLENSG00000092871.121326.991102303.05930-0.7954010.889109.60550HepG2FXR1
RFFLENSG00000092871.12956.409102136.60780-1.1596019.3610017.67700HepG2G3BP1
RFFLENSG00000092871.121676.953202268.04450-0.435603.892902.82510HepG2G3BP2
RFFLENSG00000092871.12602.66900890.92120-0.563904.825603.64060HepG2GEMIN5
RFFLENSG00000092871.12934.081101216.52700-0.381102.399601.45570HepG2GNB2L1
RFFLENSG00000092871.12865.507501334.62310-0.624804.269302.89360HepG2GRSF1
RFFLENSG00000092871.12898.671501178.01370-0.390503.333602.63250HepG2HNRNPA1
RFFLENSG00000092871.121294.923001565.15490-0.273402.861901.91420HepG2HNRNPA2B1
RFFLENSG00000092871.121519.899001211.440900.327204.027803.17860HepG2HNRNPF
RFFLENSG00000092871.121328.131602163.08270-0.703709.770108.52540HepG2HNRNPK
RFFLENSG00000092871.12843.260701433.40050-0.7654012.5271010.75190HepG2HNRNPM
RFFLENSG00000092871.12838.231601301.66440-0.6349012.6439011.42610HepG2HNRNPU
RFFLENSG00000092871.121558.070201192.921700.385202.886302.14680HepG2IGF2BP1
RFFLENSG00000092871.121192.776902037.95410-0.772803.304002.22780HepG2IGF2BP3
RFFLENSG00000092871.121020.712501329.60610-0.381406.206905.15200HepG2ILF2
RFFLENSG00000092871.121171.936902184.41880-0.898409.899807.91300HepG2KHSRP
RFFLENSG00000092871.121164.448001973.89160-0.761407.565606.17890HepG2LARP4
RFFLENSG00000092871.12884.683501191.66010-0.429703.510402.23330HepG2LARP7
RFFLENSG00000092871.121145.004002316.81270-1.0168014.7292013.35560HepG2MATR3
RFFLENSG00000092871.12692.307201681.33790-1.2801031.9286029.69020HepG2MSI2
RFFLENSG00000092871.121163.575302371.43250-1.0272016.1869014.73960HepG2NCBP2
RFFLENSG00000092871.121421.468501688.71680-0.248502.161801.48610HepG2NOL12
RFFLENSG00000092871.122143.087201317.720000.701504.457003.31510HepG2PABPC1
RFFLENSG00000092871.121658.673802112.12620-0.348702.483801.79620HepG2PABPC4
RFFLENSG00000092871.12924.097801288.41800-0.479507.238905.97270HepG2PARN
RFFLENSG00000092871.121764.718002212.21910-0.326104.943804.16910HepG2PCBP1
RFFLENSG00000092871.12869.046401160.97970-0.417804.910103.95690HepG2PPIL4
RFFLENSG00000092871.121608.479202251.00600-0.484909.871008.96360HepG2PTBP1
RFFLENSG00000092871.121348.609201612.04430-0.257401.843801.34350HepG2PUF60
RFFLENSG00000092871.121661.585101445.495500.200902.110501.55440HepG2PUS1
RFFLENSG00000092871.121936.007302437.91560-0.332604.076703.33870HepG2QKI
RFFLENSG00000092871.121120.535701949.93000-0.7992018.8549017.74850HepG2RBM22
RFFLENSG00000092871.121823.901002212.55730-0.278702.482501.83980HepG2RBM25
RFFLENSG00000092871.12908.569001436.91760-0.661306.847205.28250HepG2RBM27
RFFLENSG00000092871.12901.865301166.83750-0.371602.354301.37940HepG2RCC2
RFFLENSG00000092871.121164.804602505.16150-1.1048043.1639041.60260HepG2NELFE
RFFLENSG00000092871.121255.845902333.20300-0.8937029.6420028.01050HepG2RECQL
RFFLENSG00000092871.122061.711401305.045200.659608.936707.81690HepG2RPLP0
RFFLENSG00000092871.12486.69790973.56200-1.0002011.9425010.77200HepG2RPS19
RFFLENSG00000092871.12801.894601325.27330-0.724808.257006.92180HepG2RPS2
RFFLENSG00000092871.121026.185901447.58600-0.496403.202702.34360HepG2RPS3A
RFFLENSG00000092871.121019.65490685.762800.572204.189203.24540HepG2RRP9
RFFLENSG00000092871.121357.907701866.06100-0.458602.869102.18220HepG2SF3A3
RFFLENSG00000092871.122365.972401211.048800.9661018.6904017.02990HepG2SF3B1
RFFLENSG00000092871.121562.227102343.60500-0.5851013.7686012.60540HepG2SF3B4
RFFLENSG00000092871.12838.899201351.80190-0.6883017.5904016.18160HepG2SMN1
RFFLENSG00000092871.121395.616102446.20920-0.8096026.7202025.58010HepG2SRSF1
RFFLENSG00000092871.121355.023101591.68170-0.232202.289501.71330HepG2SRSF5
RFFLENSG00000092871.121666.620201190.206800.485608.377707.28060HepG2SRSF7
RFFLENSG00000092871.12819.404601912.21290-1.2226048.9975047.49260HepG2SSB
RFFLENSG00000092871.121478.127101957.56840-0.405302.828101.53340HepG2SSRP1
RFFLENSG00000092871.12839.899901259.18420-0.584204.379002.96330HepG2STIP1
RFFLENSG00000092871.121235.587701810.16110-0.5509012.4585011.30190HepG2SUCLG1
RFFLENSG00000092871.121497.457202198.72870-0.5542010.650709.66460HepG2TAF15
RFFLENSG00000092871.12983.101701264.78960-0.363503.483602.93630HepG2TIAL1
RFFLENSG00000092871.121081.152901574.93000-0.542706.856505.38270HepG2TUFM
RFFLENSG00000092871.122436.938501777.242600.455304.433303.64700HepG2U2AF1
RFFLENSG00000092871.121133.320101654.91680-0.546208.408107.29960HepG2UPF1
RFFLENSG00000092871.121364.938601700.97810-0.317503.012101.92490HepG2UTP18
RFFLENSG00000092871.12849.351001355.00070-0.673905.055703.65100HepG2XRCC6
RFFLENSG00000092871.12647.46890880.75700-0.443903.115102.34700HepG2XRN2
RFFLENSG00000092871.121069.364201492.90250-0.481409.142008.03990HepG2ZC3H8
RFFLENSG00000092871.122164.635001820.083200.250003.372402.78560HepG2ZNF622
RFFLENSG00000092871.121466.437401207.196400.280601.873401.33140K562AKAP8L
RFFLENSG00000092871.12792.993701003.21090-0.339203.179701.98700K562CPEB4
RFFLENSG00000092871.12924.64120656.442400.494104.515903.51520K562CPSF6
RFFLENSG00000092871.12735.73410607.428500.276401.935901.31570K562EIF2S2
RFFLENSG00000092871.12521.42990682.62890-0.388602.574401.78280K562EIF4A3
RFFLENSG00000092871.12444.54800709.90840-0.675308.222607.24930K562FXR1
RFFLENSG00000092871.12832.62820675.246100.302202.360101.31510K562GLRX3
RFFLENSG00000092871.12638.95620809.39690-0.341102.452601.73900K562GRSF1
RFFLENSG00000092871.121188.46680927.452400.357702.636801.85930K562HSPD1
RFFLENSG00000092871.121583.860901281.103100.306002.581801.78760K562KIF1C
RFFLENSG00000092871.12806.91200535.206500.592203.777102.67130K562KRR1
RFFLENSG00000092871.12599.37320821.97170-0.455604.049803.02720K562MAGOH
RFFLENSG00000092871.121137.20280788.807200.527609.447808.18000K562NSUN2
RFFLENSG00000092871.121120.55220692.949700.693302.955001.92180K562PABPN1
RFFLENSG00000092871.12348.68620529.39160-0.602404.064303.15390K562PRPF8
RFFLENSG00000092871.12541.80160798.59540-0.559705.874504.93630K562PTBP1
RFFLENSG00000092871.121108.316201324.16760-0.256702.081701.37400K562PUF60
RFFLENSG00000092871.121153.618701408.80720-0.288302.882201.79290K562PUM1
RFFLENSG00000092871.121753.794601166.488300.5882010.247009.13070K562RBM15
RFFLENSG00000092871.12598.32890765.76950-0.356002.379701.60560K562RBM22
RFFLENSG00000092871.12609.50410805.84710-0.402902.758501.66890K562NELFE
RFFLENSG00000092871.121095.21580778.337300.492606.440305.23830K562SF3A3
RFFLENSG00000092871.12849.91010596.125800.511603.426602.34190K562SF3B1
RFFLENSG00000092871.121033.66390797.422100.374302.722201.79280K562SRPK2
RFFLENSG00000092871.12487.89450782.88730-0.682207.665606.49580K562SRSF1
RFFLENSG00000092871.121068.04760820.903600.379602.564301.36380K562STAU1
RFFLENSG00000092871.12548.55180719.33950-0.391003.025102.16260K562SYNCRIP
RFFLENSG00000092871.12717.66330535.567200.422102.587201.68540K562TIAL1
RFFLENSG00000092871.12800.63110569.086300.492404.099202.89970K562TRIM56
RFFLENSG00000092871.121099.05510715.672200.618807.635806.14090K562WDR3
RFFLENSG00000092871.12909.07380744.207700.288602.787101.93780K562WDR43
RFFLENSG00000092871.121470.935501066.963700.463103.561302.55940K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RFFL is not available on ENCORE database.





13 RBPs can affect the splicing of RFFL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERFFLENSG00000092871.12chr17-3334175833341782333390673333916833343388333435990.228000.004020.06357includedK562SRSF1
SERFFLENSG00000092871.12chr17-333445413334462533343388333435993334838933348800-0.234000.002740.04694excludedK562SRSF1
SERFFLENSG00000092871.12chr17-333417583334178233339020333391683334338833343599-0.348000.002650.04540excludedK562SF3B4
SERFFLENSG00000092871.12chr17-333417583334178233339020333391683334338833343599-0.264000.002890.07016excludedK562AKAP8L
SERFFLENSG00000092871.12chr17-3335220133352359333486403334880033353392333535800.072000.000580.01705includedHepG2HNRNPK
SERFFLENSG00000092871.12chr17-333417583334178233339020333391683334338833343599-0.204000.000260.00449excludedHepG2U2AF2
SERFFLENSG00000092871.12chr17-333483893334880033344541333446253335339233353580-0.085000.001390.06587excludedHepG2PTBP1
SERFFLENSG00000092871.12chr17-3334175833341782333390673333916833343388333435990.113000.001230.04966includedHepG2MATR3
SERFFLENSG00000092871.12chr17-333483893334880033344541333446253335339233353580-0.260000.000020.00246excludedHepG2HNRNPL
SERFFLENSG00000092871.12chr17-333445413334462533343388333435993334838933348800-0.239000.000000.00000excludedHepG2SRSF1
SERFFLENSG00000092871.12chr17-333417583334178233339067333391683334338833343599-0.121000.003040.07210excludedHepG2SF3A3
SERFFLENSG00000092871.12chr17-3334175833341782333390673333916833343388333435990.121000.000640.04802includedHepG2IGF2BP3
SERFFLENSG00000092871.12chr17-333483893334880033344541333446253335339233353580-0.095000.000590.03184excludedHepG2PCBP1
SERFFLENSG00000092871.12chr17-333417583334178233339067333391683334338833343599-0.205000.000180.01189excludedHepG2SF3B4
SERFFLENSG00000092871.12chr17-333417583334178233339020333391683334338833343599-0.269000.001040.02820excludedK562RBM15
SERFFLENSG00000092871.12chr17-3334175833341782333390673333916833343388333435990.126000.000510.08546includedHepG2DDX55
SERFFLENSG00000092871.12chr17-3334175833341782333390203333916833343388333435990.229000.003260.09619includedK562PTBP1
MXERFFLENSG00000092871.12chr17-3334838933348800333533923335358033343388333435993339059433390759-0.155000.006690.096792includedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RFFL is not avaliable on ENCORE database.