PWWP2A

General Information

Gene Name       : PWWP2A
Gene ID             : ENSG00000170234.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PWWP2A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PWWP2AENSG00000170234.1219.7816.9718.38ENCSR000AEF
HepG2PWWP2AENSG00000170234.127.6611.919.79ENCSR985KAT
K562PWWP2AENSG00000170234.1211.3717.6814.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PWWP2A is not avaliable on ENCORE database.



Proteins bound to RNA
  • PWWP2A RNA is bound by 12 proteins.  







eCLIP assay for PWWP2A is not avaliable on ENCORE database.





12 proteins are bound to PWWP2A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5159520990159521093-3'-UTR,CDS,intron-Distal,intron-Proximal4.6896015.06060K562U2AF2
chr5159521022159521092-3'-UTR,CDS,intron-Distal,intron-Proximal4.0895812.93110HepG2U2AF2
chr5159518572159518630-3'-UTR,intron-Distal3.231355.75036K562PUM2
chr5159521038159521093-CDS,intron-Distal,intron-Proximal3.637953.69214K562SF3B4
chr5159520075159520205-CDS,intron-Distal,intron-Proximal4.728304.34038HepG2BCLAF1
chr5159521034159521090-CDS,intron-Distal,intron-Proximal4.726455.81941K562U2AF1
chr5159545761159545826-CDS,intron-Distal3.875015.13777HepG2PRPF8
chr5159546313159546392-CDS,intron-Distal4.040583.36385K562UCHL5
chr5159545690159545804-intron-Distal3.400285.03897K562PRPF8
chr5159529058159529121-intron-Distal3.816443.43813HepG2HNRNPC
chr5159521093159521136-intron-Distal,intron-Proximal4.569203.42835K562SF3B4
chr5159535728159535835-intron-Distal3.078403.57533K562KHSRP
chr5159545726159545746-intron-Distal5.004253.65355K562EFTUD2
chr5159538071159538161-intron-Distal3.743603.08243K562ILF3
chr5159545712159545768-intron-Distal4.738118.42614HepG2EFTUD2
chr5159529594159529678-intron-Distal3.833805.09669HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PWWP2A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PWWP2A is not available on ENCORE database.

  • 24 RBPs can affect the levels of PWWP2A.  








The Knockdown/knockout RNA-Seq assay for PWWP2A is not available on ENCORE database.





24 RBPs can affect the gene expression of PWWP2A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PWWP2AENSG00000170234.8277.28240449.65890-0.697505.191104.40310HepG2BOP1
PWWP2AENSG00000170234.8327.25020443.01350-0.437003.052702.38370HepG2CELF1
PWWP2AENSG00000170234.8195.75390285.54480-0.544702.038201.36420HepG2DDX55
PWWP2AENSG00000170234.8208.75350355.44500-0.767802.141101.59100HepG2DDX6
PWWP2AENSG00000170234.8166.21190241.52170-0.539102.762102.05980HepG2DNAJC21
PWWP2AENSG00000170234.8321.43670433.93590-0.432901.933301.35730HepG2HNRNPL
PWWP2AENSG00000170234.8374.23420472.36070-0.335902.024901.37010HepG2NOL12
PWWP2AENSG00000170234.8419.30970326.723200.359802.277601.56800HepG2PRPF4
PWWP2AENSG00000170234.8334.50940450.90520-0.430802.527801.95490HepG2PUF60
PWWP2AENSG00000170234.8372.22630478.65070-0.362802.791502.19680HepG2PUM1
PWWP2AENSG00000170234.8335.51150478.30430-0.511603.697602.92790HepG2PUM2
PWWP2AENSG00000170234.8326.06460441.98950-0.438902.447301.78140HepG2SF3B1
PWWP2AENSG00000170234.8345.79040432.33730-0.322302.022801.40560HepG2SLBP
PWWP2AENSG00000170234.8576.88360367.499300.650406.835006.17270HepG2SRSF1
PWWP2AENSG00000170234.8230.57140298.98780-0.374901.963801.48400HepG2SRSF9
PWWP2AENSG00000170234.8316.93010435.30040-0.457802.513401.81760HepG2TARDBP
PWWP2AENSG00000170234.8201.75700264.13760-0.388701.927501.44030HepG2TRIM56
PWWP2AENSG00000170234.8604.71380338.649700.836405.059404.22360HepG2U2AF1
PWWP2AENSG00000170234.81142.78470719.038100.668307.266806.38800K562AQR
PWWP2AENSG00000170234.8894.40960672.102400.412203.996002.91730K562DKC1
PWWP2AENSG00000170234.8428.08570546.81750-0.353202.219801.40050K562MATR3
PWWP2AENSG00000170234.8409.80660532.32170-0.377402.498401.86270K562PTBP1
PWWP2AENSG00000170234.8247.56220343.92550-0.474302.450101.52130K562RCC2
PWWP2AENSG00000170234.8540.04760393.638500.456102.452801.68100K562SYNCRIP
PWWP2AENSG00000170234.8391.56970528.16380-0.431702.328301.67640K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PWWP2A is not available on ENCORE database.





7 RBPs can affect the splicing of PWWP2A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPWWP2AENSG00000170234.8chr5-1595355511595356211595207641595210721595458111595458400.699000.000000.00000includedK562SRSF1
SEPWWP2AENSG00000170234.8chr5-159507657159507777159504850159505175159520107159521072-0.506000.001360.02199excludedK562PUS1
SEPWWP2AENSG00000170234.8chr5-1595076571595077771595048501595051751595201071595210720.573000.002120.07867includedHepG2SFPQ
SEPWWP2AENSG00000170234.8chr5-159507657159507777159504850159505175159520107159521072-0.714000.000080.00685excludedHepG2PTBP1
SEPWWP2AENSG00000170234.8chr5-1595076571595077771595048501595051751595201071595210720.579000.000130.02734includedHepG2HNRNPUL1
SEPWWP2AENSG00000170234.8chr5-1595355511595356211595207641595210721595458111595458400.520000.005060.08905includedHepG2SRSF1
SEPWWP2AENSG00000170234.8chr5-159507657159507777159504850159505175159520107159521072-0.761000.000000.00026excludedHepG2SRSF1
SEPWWP2AENSG00000170234.8chr5-159507657159507777159504850159505175159520107159521072-0.908000.000000.00007excludedHepG2PCBP1
SEPWWP2AENSG00000170234.8chr5-1595355511595356211595207641595210721595458111595458400.282000.001690.05623includedK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PWWP2A is not avaliable on ENCORE database.