POLR3B

General Information

Gene Name       : POLR3B
Gene ID             : ENSG00000013503.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: POLR3B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLR3BENSG00000013503.96.426.746.58ENCSR000AEF
HepG2POLR3BENSG00000013503.97.019.488.25ENCSR985KAT
K562POLR3BENSG00000013503.911.2912.0511.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLR3B is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLR3B RNA is bound by 5 proteins.  







eCLIP assay for POLR3B is not avaliable on ENCORE database.





5 proteins are bound to POLR3B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12106763067106763129+CDS,intron-Proximal3.422593.27569HepG2BCLAF1
chr12106751697106751818+CDS,intron-Proximal4.4592010.26986HepG2PRPF8
chr12106821032106821090+CDS4.026883.02457HepG2BCLAF1
chr12106854538106854618+intron-Distal3.640083.62418K562PTBP1
chr12106842652106842782+intron-Distal4.352543.83958HepG2QKI
chr12106824301106824355+intron-Distal,intron-Proximal4.323284.77477HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLR3B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLR3B is not available on ENCORE database.

  • 80 RBPs can affect the levels of POLR3B.  








The Knockdown/knockout RNA-Seq assay for POLR3B is not available on ENCORE database.





80 RBPs can affect the gene expression of POLR3B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLR3BENSG00000013503.5755.35340397.585400.925808.189807.32680HepG2AKAP1
POLR3BENSG00000013503.5482.04720621.39200-0.366303.032502.31890HepG2AUH
POLR3BENSG00000013503.5844.72930584.417700.531404.629203.87890HepG2BOP1
POLR3BENSG00000013503.5460.29710312.538600.558403.341502.49730HepG2CIRBP
POLR3BENSG00000013503.5372.35200261.664700.508802.960402.01230HepG2DDX24
POLR3BENSG00000013503.5205.48110364.45370-0.826704.392203.44060HepG2DDX55
POLR3BENSG00000013503.5212.31160327.18530-0.623902.990502.35060HepG2DDX6
POLR3BENSG00000013503.5213.97220314.49770-0.555602.612102.03620HepG2EIF2S1
POLR3BENSG00000013503.5240.94840347.54070-0.528502.526801.91510HepG2EIF4A3
POLR3BENSG00000013503.5280.37310196.122600.515502.338901.52240HepG2GEMIN5
POLR3BENSG00000013503.5436.70120608.20890-0.477902.730202.09290HepG2GPKOW
POLR3BENSG00000013503.5363.13100259.462600.484902.478801.86450HepG2HNRNPA1
POLR3BENSG00000013503.5346.83200466.59000-0.427903.276502.50070HepG2HNRNPF
POLR3BENSG00000013503.5279.90030354.67300-0.341601.990501.40720HepG2HNRNPL
POLR3BENSG00000013503.5449.43000580.42410-0.369001.911801.38020HepG2HNRNPLL
POLR3BENSG00000013503.5212.14370286.69480-0.434502.422801.85250HepG2HNRNPU
POLR3BENSG00000013503.5359.85370459.45630-0.352502.139901.49730HepG2IGF2BP1
POLR3BENSG00000013503.5231.83270350.82560-0.597703.063602.37330HepG2MAGOH
POLR3BENSG00000013503.5259.51880386.07500-0.573004.189803.25170HepG2NOL12
POLR3BENSG00000013503.5335.61140514.65010-0.616804.283803.35820HepG2NSUN2
POLR3BENSG00000013503.5206.68540283.78050-0.457302.458901.65630HepG2PARN
POLR3BENSG00000013503.5553.76990391.209400.501205.203904.44290HepG2PUM1
POLR3BENSG00000013503.5501.06110342.227800.549904.080403.27540HepG2RBM25
POLR3BENSG00000013503.5409.98230263.589900.637203.428602.24740HepG2RCC2
POLR3BENSG00000013503.5303.34040502.65570-0.728606.332405.35840HepG2RPLP0
POLR3BENSG00000013503.5240.62760138.788600.793803.506202.60450HepG2RPS3A
POLR3BENSG00000013503.5180.43520255.31520-0.500802.704102.06540HepG2SAFB2
POLR3BENSG00000013503.5664.65900458.432200.535802.776802.10150HepG2SF3A3
POLR3BENSG00000013503.5275.26770673.51020-1.2909025.6834024.55780HepG2SRFBP1
POLR3BENSG00000013503.5701.23480378.369000.8900013.2159012.34820HepG2SRSF1
POLR3BENSG00000013503.5371.37230458.41480-0.303801.961201.36440HepG2SRSF7
POLR3BENSG00000013503.5170.84490307.82880-0.849407.315906.49490HepG2SRSF9
POLR3BENSG00000013503.5450.11910584.75510-0.377503.140502.60220HepG2SSB
POLR3BENSG00000013503.5163.58240340.11020-1.056009.995809.03610HepG2TAF15
POLR3BENSG00000013503.5429.66100274.318800.647202.372801.38520HepG2TBRG4
POLR3BENSG00000013503.5193.20210281.06750-0.540803.420702.80840HepG2TRIM56
POLR3BENSG00000013503.5593.48490352.941300.749703.517902.81420HepG2U2AF1
POLR3BENSG00000013503.5130.07010214.35430-0.720703.192802.37880HepG2UCHL5
POLR3BENSG00000013503.5538.90390392.517600.457203.848003.15980HepG2UTP3
POLR3BENSG00000013503.5921.089701293.44740-0.489804.564402.96820K562ABCF1
POLR3BENSG00000013503.5384.51560815.74810-1.0851020.5902019.15430K562AGGF1
POLR3BENSG00000013503.5550.08950848.81670-0.625804.818603.94840K562AKAP8L
POLR3BENSG00000013503.51493.66670911.571700.712303.317201.95560K562APOBEC3C
POLR3BENSG00000013503.5470.93520874.31000-0.892605.282304.51650K562AQR
POLR3BENSG00000013503.5722.30820890.60120-0.302202.436901.58410K562ATP5C1
POLR3BENSG00000013503.5721.62280957.09540-0.407403.090201.53310K562DDX19B
POLR3BENSG00000013503.5450.80910569.76990-0.337902.501801.35410K562DDX21
POLR3BENSG00000013503.52090.15270883.644601.2420049.1738046.78410K562DDX47
POLR3BENSG00000013503.5622.07590427.941800.539603.902302.80390K562EFTUD2
POLR3BENSG00000013503.5546.56990248.771401.135507.417005.73110K562EIF3A
POLR3BENSG00000013503.5672.45970458.217700.553303.690302.48020K562EIF3D
POLR3BENSG00000013503.5674.03930444.080000.601906.387505.19460K562EIF3G
POLR3BENSG00000013503.5351.73300478.00180-0.442503.022401.69790K562EXOSC5
POLR3BENSG00000013503.5661.46620929.68870-0.491103.992802.96100K562FIP1L1
POLR3BENSG00000013503.5716.13300340.705801.0716018.3350016.88600K562FXR1
POLR3BENSG00000013503.5882.821101121.66410-0.345402.644901.90510K562GRSF1
POLR3BENSG00000013503.5588.91740462.922800.347202.272801.30370K562HNRNPA1
POLR3BENSG00000013503.5584.04490907.75190-0.636202.659101.47290K562HNRNPA2B1
POLR3BENSG00000013503.5681.34260900.82850-0.402902.960602.10520K562KIF1C
POLR3BENSG00000013503.5556.99980404.252100.462303.127301.62910K562LARP7
POLR3BENSG00000013503.5347.62660464.17840-0.417102.558001.74950K562MAGOH
POLR3BENSG00000013503.5375.95600677.32390-0.8493014.3004012.78780K562NSUN2
POLR3BENSG00000013503.5287.75410411.12610-0.514703.164301.60750K562NUSAP1
POLR3BENSG00000013503.5422.86850794.16510-0.909204.627203.25670K562PABPN1
POLR3BENSG00000013503.5572.71300412.972400.471703.127502.08750K562PCBP2
POLR3BENSG00000013503.5676.104701055.31320-0.642406.932505.52960K562PPIG
POLR3BENSG00000013503.5885.20450416.436101.0878014.5302012.79780K562PRPF8
POLR3BENSG00000013503.5263.90520374.46090-0.504802.526001.66860K562PSIP1
POLR3BENSG00000013503.5584.36590450.991200.373702.578601.93390K562PTBP1
POLR3BENSG00000013503.5549.42340841.83790-0.615605.493904.76060K562PUS1
POLR3BENSG00000013503.5554.89130820.20720-0.563806.228905.36470K562RBM15
POLR3BENSG00000013503.5875.07910424.202801.0446011.7803010.06680K562RPS19
POLR3BENSG00000013503.5449.16910311.531200.527802.771201.76760K562RPS3
POLR3BENSG00000013503.5690.64830415.567400.732807.614205.85750K562SAFB
POLR3BENSG00000013503.5562.79250684.72920-0.282902.209801.36520K562SRPK2
POLR3BENSG00000013503.5604.02210442.141100.450003.343902.57150K562SRSF1
POLR3BENSG00000013503.5337.48870508.50360-0.591405.795704.08640K562SRSF7
POLR3BENSG00000013503.5940.011001219.87940-0.376002.906801.50900K562SSRP1
POLR3BENSG00000013503.5860.695701115.78150-0.374502.563701.36370K562STAU1
POLR3BENSG00000013503.5937.00710467.783501.0021017.3910015.36820K562SYNCRIP
POLR3BENSG00000013503.5250.29130360.17970-0.525102.584001.68260K562TIAL1
POLR3BENSG00000013503.5222.63930382.54300-0.780905.790004.30800K562TRIM56
POLR3BENSG00000013503.5776.317801087.80280-0.486704.128502.33700K562TRIP6
POLR3BENSG00000013503.5566.31530361.332200.648204.703603.66230K562U2AF2
POLR3BENSG00000013503.5390.52600842.10330-1.1086013.6135011.25660K562UTP3
POLR3BENSG00000013503.5397.35580614.52500-0.629005.934304.62630K562WDR3
POLR3BENSG00000013503.5843.55170639.031600.400504.617203.54410K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLR3B is not available on ENCORE database.





1 RBPs can affect the splicing of POLR3B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPOLR3BENSG00000013503.5chr12+1068572351068573981068572551068573981068530281068531460.185000.000030.00027longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POLR3B is not avaliable on ENCORE database.