HTT

General Information

Gene Name : HTT
Gene ID : ENSG00000197386.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HTT)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HTT	ENSG00000197386.12	127.89	77.20	102.55	ENCSR000AEF
HepG2	HTT	ENSG00000197386.12	31.93	24.46	28.20	ENCSR985KAT
K562	HTT	ENSG00000197386.12	16.04	15.69	15.86	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HTT is not avaliable on ENCORE database.

Proteins bound to RNA

HTT RNA is bound by 36 proteins.

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eCLIP assay for HTT is not avaliable on ENCORE database.

36 proteins are bound to HTT RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	3231388	3231486	+	intron-Distal	7.03943	118.19316	K562	AGGF1
chr4	3231323	3231387	+	intron-Distal	8.49477	87.15764	K562	AGGF1
chr4	3231179	3231228	+	intron-Distal	7.19325	72.32122	K562	AGGF1
chr4	3231231	3231285	+	intron-Distal	7.03150	62.74120	K562	AGGF1
chr4	3231125	3231155	+	intron-Distal	6.79061	53.92341	K562	AGGF1
chr4	3230815	3230866	+	intron-Distal,intron-Proximal	6.69995	52.05301	K562	AGGF1
chr4	3231155	3231179	+	intron-Distal	6.60176	47.38147	K562	AGGF1
chr4	3231098	3231125	+	intron-Distal	6.04348	41.83116	K562	AGGF1
chr4	3231018	3231050	+	intron-Distal	6.48057	41.78545	K562	AGGF1
chr4	3231390	3231508	+	intron-Distal	5.65411	38.37388	HepG2	XPO5
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 215 entries

eCLIP assay for HTT is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HTT is not available on ENCORE database.
67 RBPs can affect the levels of HTT.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HTT is not available on ENCORE database.

67 RBPs can affect the gene expression of HTT :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HTT	ENSG00000197386.6	6339.47640	3170.16000	0.99970	59.29350	57.74520	HepG2	SRSF1
HTT	ENSG00000197386.6	5365.15230	3486.47210	0.62180	23.57880	21.93370	HepG2	UPF1
HTT	ENSG00000197386.6	7099.14530	4873.09220	0.54270	17.24300	15.95230	HepG2	ETF1
HTT	ENSG00000197386.6	4791.13420	3216.37310	0.57480	16.93030	15.59890	HepG2	SUCLG1
HTT	ENSG00000197386.6	4650.26070	3159.37860	0.55760	12.00220	10.83570	HepG2	QKI
HTT	ENSG00000197386.6	4936.64650	2867.18310	0.78380	10.78390	9.51420	HepG2	G3BP1
HTT	ENSG00000197386.6	3794.15290	2828.15240	0.42380	9.56880	8.49840	HepG2	SRSF5
HTT	ENSG00000197386.6	4002.90480	3065.67490	0.38470	9.19410	8.17990	HepG2	PUS1
HTT	ENSG00000197386.6	2996.99560	2228.12230	0.42760	7.52750	6.41400	HepG2	DNAJC21
HTT	ENSG00000197386.6	5122.14360	3266.51660	0.64890	7.28490	6.09810	HepG2	FIP1L1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 70 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HTT is not available on ENCORE database.

11 RBPs can affect the splicing of HTT :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	HTT	ENSG00000197386.6	chr4	+	3204708	3204793	3201458	3201666	3205733	3205875	0.10600	0.00011	0.05080	included	K562	BUD13
SE	HTT	ENSG00000197386.6	chr4	+	3204703	3204793	3201458	3201666	3205733	3205875	0.17400	0.00013	0.04372	included	HepG2	BCLAF1
A5SS	HTT	ENSG00000197386.6	chr4	+	3215684	3215883	3215684	3215862	3216836	3216938	0.08500	0.00022	0.02229	longer	HepG2	SF3A3
SE	HTT	ENSG00000197386.6	chr4	+	3204708	3204793	3201458	3201666	3205733	3205875	0.11800	0.00026	0.02276	included	HepG2	FTO
RI	HTT	ENSG00000197386.6	chr4	+	3189377	3190820	3189377	3189613	3190677	3190820	0.08400	0.00046	0.00635	included	HepG2	TAF15
A5SS	HTT	ENSG00000197386.6	chr4	+	3211553	3211696	3211553	3211676	3213655	3213869	0.13300	0.00062	0.07024	longer	HepG2	FTO
SE	HTT	ENSG00000197386.6	chr4	+	3201458	3201666	3189377	3190820	3205733	3205875	-0.09600	0.00094	0.02916	excluded	HepG2	SF3A3
RI	HTT	ENSG00000197386.6	chr4	+	3189377	3190820	3189377	3189613	3190677	3190820	-0.08600	0.00190	0.03085	excluded	K562	FXR1
RI	HTT	ENSG00000197386.6	chr4	+	3189377	3190820	3189377	3189613	3190677	3190820	0.07900	0.00303	0.02869	included	K562	AKAP8L
SE	HTT	ENSG00000197386.6	chr4	+	3204703	3204793	3201458	3201666	3205733	3205875	-0.06900	0.00481	0.08594	excluded	HepG2	SRSF1

Showing 1 to 10 of 14 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HTT

General Information

Functions

Localization

Domains (AlphaFold: HTT)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HTT is not avaliable on ENCORE database.

36 proteins are bound to HTT RNA:

eCLIP assay for HTT is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HTT is not available on ENCORE database.

67 RBPs can affect the gene expression of HTT :

The Knockdown/knockout RNA-Seq assay for HTT is not available on ENCORE database.

11 RBPs can affect the splicing of HTT :

The Knockdown/knockout RNA-Seq assay for HTT is not avaliable on ENCORE database.