GPHN

General Information

Gene Name       : GPHN
Gene ID             : ENSG00000171723.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GPHN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GPHNENSG00000171723.1524.1425.4824.81ENCSR000AEF
HepG2GPHNENSG00000171723.1520.8627.9524.41ENCSR985KAT
K562GPHNENSG00000171723.158.999.429.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GPHN is not avaliable on ENCORE database.



Proteins bound to RNA
  • GPHN RNA is bound by 20 proteins.  







eCLIP assay for GPHN is not avaliable on ENCORE database.





20 proteins are bound to GPHN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr146729119567291286+3'-UTR,CDS,intron-Distal,intron-Proximal4.7483511.47391HepG2BCLAF1
chr146734665267346692+3'-UTR,CDS,intron-Proximal3.012875.00751HepG2BCLAF1
chr146734671567346754+3'-UTR,CDS,intron-Proximal3.515933.64266HepG2PPIG
chr146697499666975085+5'-UTR6.2314118.10989HepG2PCBP2
chr146697509566975138+5'-UTR4.463906.14899HepG2PCBP2
chr146697498766975079+5'-UTR3.946665.98979K562PCBP1
chr146738956767389658+CDS,intron-Proximal3.158813.41665HepG2GRWD1
chr146745236767452429+CDS,intron-Distal,intron-Proximal3.408863.62357HepG2U2AF2
chr146738959167389652+CDS4.215076.65960HepG2BCLAF1
chr146707701267077090+intron-Distal3.489463.68462HepG2MATR3
chr146697585966975943+intron-Distal3.152223.01293HepG2NKRF
chr146714891667149038+intron-Distal3.935096.98930HepG2U2AF2
chr146704137567041485+intron-Distal4.6373410.78639HepG2HNRNPM
chr146704278967042941+intron-Distal6.2625419.59070HepG2HNRNPM
chr146702524267025341+intron-Distal3.720303.02234K562KHSRP
chr146699544266995519+intron-Distal3.799504.91037K562EXOSC5
chr146700284767002895+intron-Distal3.101503.10883HepG2SUGP2
chr146704294167042986+intron-Distal4.550865.42395HepG2HNRNPM
chr146701078667010860+intron-Distal4.539159.78100HepG2PTBP1
chr146726266067262729+intron-Distal4.653955.68967HepG2PCBP2
chr146701076467010885+intron-Distal4.232124.69074K562PTBP1
chr146743209567432151+intron-Distal,intron-Proximal4.151573.35169HepG2U2AF2
chr146710122767101267+intron-Distal5.142047.15660HepG2HNRNPM
chr146699642966996518+intron-Distal3.770023.16028HepG2SUGP2
chr146753316867533273+intron-Distal3.905603.29248HepG2SUGP2
chr146699532266995392+intron-Distal3.740064.61905HepG2MATR3
chr146699416266994227+intron-Distal3.385063.72904K562EXOSC5
chr146701813167018210+intron-Distal4.214504.36036HepG2SUGP2
chr146726828167268379+intron-Distal5.069668.17201HepG2PCBP2
chr146699345866993501+intron-Distal4.426894.12480HepG2HNRNPM
chr146704249367042574+intron-Distal4.181093.72398HepG2SFPQ
chr146716396767164106+intron-Distal3.105963.48890K562KHSRP
chr146731384867313924+intron-Distal4.525974.85866HepG2QKI
chr146714568567145773+intron-Distal3.982413.60235HepG2HNRNPM
chr146701462567014734+intron-Distal4.600345.93882HepG2CSTF2
chr146709181067091864+intron-Distal3.839543.38413HepG2HNRNPC
chr146704272467042755+intron-Distal4.326443.62366HepG2HNRNPM
chr146700916667009268+intron-Distal3.476603.83822HepG2PTBP1
chr146710115667101208+intron-Distal5.488238.59719HepG2HNRNPM
chr146704318367043272+intron-Distal3.566963.64762HepG2QKI
chr146704097267041050+intron-Distal4.738566.74598HepG2QKI
chr146707575567075827+intron-Distal4.482415.16513HepG2HNRNPM
chr146697591166976036+intron-Distal3.523466.07855HepG2SFPQ
chr146729911767299199+intron-Distal6.0879515.78113HepG2QKI
chr146697613166976289+intron-Distal,intron-Proximal3.135446.81051HepG2SFPQ
chr146700916567009234+intron-Distal3.796203.19026HepG2HNRNPL
chr146700114767001266+intron-Distal3.950793.24603K562KHSRP
chr146697616266976223+intron-Distal,intron-Proximal4.168003.99137K562NONO
chr146708307967083131+intron-Distal3.753424.61500HepG2HNRNPM
chr146699634066996390+intron-Distal4.490714.90578HepG2HNRNPM
chr146718119567181261+intron-Distal3.208503.14999K562EXOSC5
chr146707574467075802+intron-Distal4.639245.70028HepG2MATR3
chr146715645167156529+intron-Distal4.526143.34098HepG2HNRNPM
chr146742571267425806+intron-Distal4.566965.04993HepG2QKI
chr146762665367626725+intron-Distal4.607054.51735HepG2QKI
chr146700346167003550+intron-Distal4.305413.97018HepG2HNRNPM
chr146720037767200434+intron-Distal4.379764.51735HepG2QKI
chr146718306067183144+intron-Distal4.167983.89080K562EXOSC5
chr146699382466993862+intron-Distal4.007023.01445K562EXOSC5
chr146697867666978806+intron-Distal4.082314.10688K562KHSRP
chr146720358967203693+intron-Distal5.201828.66996HepG2PTBP1
chr146710136767101451+intron-Distal4.373099.46032HepG2HNRNPM
chr146700903467009100+intron-Distal3.978283.51329HepG2MATR3
chr146751245567512574+intron-Distal4.133073.41738HepG2PTBP1
chr146729840267298452+intron-Distal4.288773.30440HepG2QKI
chr146749021567490295+intron-Distal,intron-Proximal4.612233.83958HepG2QKI
chr146699544366995496+intron-Distal4.270763.51329HepG2MATR3
chr146729908767299117+intron-Distal4.232043.16986HepG2QKI
chr146726265867262747+intron-Distal5.017195.85495HepG2QKI
chr146700337167003427+intron-Distal4.006983.54208HepG2SUGP2
chr146707597467076035+intron-Distal4.232183.96879HepG2MATR3
chr146715664067156695+intron-Distal4.664774.48623K562EXOSC5
chr146704237967042421+intron-Distal4.301124.38558HepG2HNRNPM
chr146715602367156070+intron-Distal4.325733.59909K562EXOSC5
chr146707720567077254+intron-Distal4.092693.24322HepG2MATR3
chr146715699767157035+intron-Distal4.014993.30687K562EXOSC5
chr146739814867398232+intron-Distal4.118494.07628HepG2PTBP1
chr146701084067010913+intron-Distal3.728783.16028HepG2SUGP2
chr146716796067168065+intron-Distal3.885504.12694HepG2CSTF2
chr146700593767006027+intron-Distal3.415524.28254HepG2MATR3
chr146699345966993509+intron-Distal3.903796.11008K562EXOSC5
chr146716397967164090+intron-Distal3.356453.81210HepG2KHSRP
chr146715384367153874+intron-Distal3.846053.01445K562EXOSC5
chr146697596766976036+intron-Distal3.933453.06347K562NONO
chr146715883767158901+intron-Distal3.426324.09242HepG2QKI
chr146751218467512279+intron-Distal4.057073.53723HepG2PTBP1
chr146715990267160011+intron-Distal3.694063.02234K562KHSRP
chr146710120867101227+intron-Distal4.663144.66899HepG2HNRNPM
chr146700906367009112+intron-Distal4.006983.54208HepG2SUGP2
chr146709922367099281+intron-Distal3.066403.84371HepG2HNRNPC
chr146704288967042985+intron-Distal4.448223.28836HepG2GRSF1
chr146699240566992464+intron-Distal3.686975.20960K562EXOSC5
chr146700631067006349+intron-Distal3.846023.54208HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GPHN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GPHN is not available on ENCORE database.

  • 61 RBPs can affect the levels of GPHN.  








The Knockdown/knockout RNA-Seq assay for GPHN is not available on ENCORE database.





61 RBPs can affect the gene expression of GPHN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GPHNENSG00000171723.11417.06930519.57600-0.317002.156701.46870HepG2AKAP8L
GPHNENSG00000171723.11683.54860489.538300.481503.494102.83040HepG2BOP1
GPHNENSG00000171723.11620.60230517.019300.263401.940601.37050HepG2CKAP4
GPHNENSG00000171723.11562.13330706.60240-0.330002.411501.80440HepG2CELF1
GPHNENSG00000171723.11341.91930498.30150-0.543402.477501.74080HepG2DDX55
GPHNENSG00000171723.11426.27420637.00140-0.579503.683402.97900HepG2DDX6
GPHNENSG00000171723.11630.65040494.814000.349902.675202.00820HepG2DKC1
GPHNENSG00000171723.11336.69920444.47340-0.400602.639301.94880HepG2DNAJC21
GPHNENSG00000171723.11316.44330440.57080-0.477404.119903.35530HepG2DNAJC2
GPHNENSG00000171723.11335.26070491.17060-0.550903.234802.24300HepG2EEF2
GPHNENSG00000171723.11273.22630409.46930-0.583703.538302.27650HepG2EFTUD2
GPHNENSG00000171723.11330.02850612.35420-0.891808.147607.16800HepG2EIF2S1
GPHNENSG00000171723.11514.61890676.71820-0.395102.029101.47900HepG2EIF4A3
GPHNENSG00000171723.11296.22260658.89000-1.153409.972608.70790HepG2EIF4B
GPHNENSG00000171723.11633.75900928.11690-0.550407.315906.41720HepG2ETF1
GPHNENSG00000171723.11365.41390633.38510-0.793606.718605.70260HepG2G3BP1
GPHNENSG00000171723.11352.91190487.54390-0.466202.555801.58260HepG2GNB2L1
GPHNENSG00000171723.11304.69210509.41370-0.741505.229704.36800HepG2GPKOW
GPHNENSG00000171723.11281.82570448.73180-0.671104.786503.96830HepG2HNRNPA1
GPHNENSG00000171723.11536.94180698.21300-0.378903.029402.05820HepG2HNRNPA2B1
GPHNENSG00000171723.11339.79020451.97960-0.411602.307001.43860HepG2HNRNPM
GPHNENSG00000171723.11536.65140825.39320-0.621104.290403.25120HepG2LARP4
GPHNENSG00000171723.11521.89680683.03440-0.388202.148001.56770HepG2MAGOH
GPHNENSG00000171723.11397.68840530.20010-0.414902.456801.69290HepG2MSI2
GPHNENSG00000171723.11341.22020495.87040-0.539302.221401.35900HepG2MTPAP
GPHNENSG00000171723.11394.44970703.03190-0.833707.478806.46130HepG2NCBP2
GPHNENSG00000171723.11326.83140626.08630-0.937809.104507.81410HepG2PABPC4
GPHNENSG00000171723.11311.66850490.78550-0.655106.569305.34870HepG2PARN
GPHNENSG00000171723.11404.28750593.48740-0.553802.897401.83360HepG2PCBP2
GPHNENSG00000171723.11262.71240384.53760-0.549602.477801.71170HepG2PRPF8
GPHNENSG00000171723.11479.44690719.11980-0.584905.134204.35280HepG2PUF60
GPHNENSG00000171723.11561.25930762.83060-0.442703.596402.83670HepG2PUM2
GPHNENSG00000171723.11703.93470526.806000.418104.276103.54030HepG2PUS1
GPHNENSG00000171723.11551.42240732.79350-0.410203.339602.66260HepG2QKI
GPHNENSG00000171723.11174.55860572.79050-1.7143014.6101013.10900HepG2RAVER1
GPHNENSG00000171723.11334.62710775.72960-1.2130022.7418021.54580HepG2RBM22
GPHNENSG00000171723.11435.89470665.06150-0.609505.642704.71240HepG2RBM25
GPHNENSG00000171723.11587.49280753.01760-0.358103.044802.48220HepG2NELFE
GPHNENSG00000171723.11582.71510701.34170-0.267301.849601.33120HepG2RECQL
GPHNENSG00000171723.11266.75030387.97460-0.540503.253502.59400HepG2RPS19
GPHNENSG00000171723.11339.03040531.26240-0.648005.017203.95820HepG2RPS2
GPHNENSG00000171723.11309.86950542.32660-0.807507.369805.63440HepG2RPS5
GPHNENSG00000171723.11343.41340441.56130-0.362702.457001.84400HepG2SAFB2
GPHNENSG00000171723.11252.11150389.39540-0.627203.630702.54750HepG2SERBP1
GPHNENSG00000171723.11309.83070481.17090-0.635104.467903.58830HepG2SF3B1
GPHNENSG00000171723.11449.92240704.44760-0.646807.787006.87480HepG2SF3B4
GPHNENSG00000171723.11367.94160514.92780-0.484904.630403.83410HepG2SMN1
GPHNENSG00000171723.11585.74660876.15030-0.580908.168807.43400HepG2SRFBP1
GPHNENSG00000171723.11401.47590598.20480-0.575306.498705.71690HepG2SRSF9
GPHNENSG00000171723.11904.59620760.692300.249902.074301.61400HepG2SSB
GPHNENSG00000171723.11265.68740496.09160-0.900905.932004.99900HepG2SUPV3L1
GPHNENSG00000171723.11199.91140332.53720-0.734204.005002.83190HepG2TFIP11
GPHNENSG00000171723.11547.20390702.59620-0.360602.307501.51610HepG2TUFM
GPHNENSG00000171723.11400.42220699.55490-0.8049013.8791012.88830HepG2ZNF622
GPHNENSG00000171723.11205.15060359.68910-0.810104.771304.03840K562AQR
GPHNENSG00000171723.11561.50320384.659700.545605.454204.58480K562DDX47
GPHNENSG00000171723.11132.38390250.03690-0.917405.425004.12120K562EFTUD2
GPHNENSG00000171723.11230.54900337.52290-0.549903.645002.83930K562EIF2S2
GPHNENSG00000171723.11268.25120158.233000.761404.806703.77260K562EIF3G
GPHNENSG00000171723.11207.71230311.92230-0.586603.230802.31100K562FIP1L1
GPHNENSG00000171723.11157.57110231.74240-0.556502.373401.63600K562GPKOW
GPHNENSG00000171723.11234.54390343.41240-0.550103.672902.64380K562HNRNPU
GPHNENSG00000171723.11134.86120243.31570-0.851404.431103.48300K562PRPF8
GPHNENSG00000171723.11430.73000572.34000-0.410102.250601.51570K562PUF60
GPHNENSG00000171723.11168.52240247.10400-0.552202.695001.86630K562RBM22
GPHNENSG00000171723.11126.15110220.46130-0.805403.594902.47930K562SF3B1
GPHNENSG00000171723.11109.35450180.50860-0.723103.486102.52180K562SF3B4
GPHNENSG00000171723.11144.84900252.67710-0.802704.783003.85830K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GPHN is not available on ENCORE database.





4 RBPs can affect the splicing of GPHN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGPHNENSG00000171723.11chr14+6745239867452455674319076743204267490349674903920.224000.001480.05056includedK562HNRNPU
SEGPHNENSG00000171723.11chr14+6701775867017899669752336697530967147824671479030.334000.000830.01649includedK562HNRNPC
MXEGPHNENSG00000171723.11chr14+67243181672432396729119167291284671478246714790367346656673467510.243000.004950.072521includedHepG2FTO
MXEGPHNENSG00000171723.11chr14+67291191672912846734665667346751672431816724323967382719673827860.425000.010790.067301includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GPHN is not avaliable on ENCORE database.