GABPB1

General Information

Gene Name       : GABPB1
Gene ID             : ENSG00000104064.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GABPB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GABPB1ENSG00000104064.1728.7025.3927.05ENCSR000AEF
HepG2GABPB1ENSG00000104064.1720.5525.3622.95ENCSR985KAT
K562GABPB1ENSG00000104064.1727.8022.3525.08ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GABPB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GABPB1 RNA is bound by 23 proteins.  







eCLIP assay for GABPB1 is not avaliable on ENCORE database.





23 proteins are bound to GABPB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr155059623250596292-3'-UTR,CDS,intron-Distal,intron-Proximal3.243837.19068K562YBX3
chr155057083550570953-3'-UTR,CDS,intron-Distal4.036505.47804K562ZNF622
chr155057079250570912-3'-UTR,CDS,intron-Distal3.785225.57819K562UCHL5
chr155059622750596303-3'-UTR,CDS,intron-Distal,intron-Proximal3.5725710.82288K562LIN28B
chr155059629250596331-3'-UTR,CDS,intron-Distal,intron-Proximal3.715726.16886K562YBX3
chr155059624150596287-3'-UTR,CDS,intron-Distal,intron-Proximal4.175793.43975HepG2LIN28B
chr155064719050647220-5'-UTR,intron-Distal4.965816.92731HepG2PRPF8
chr155064713550647190-5'-UTR,intron-Distal5.8176024.88330HepG2PRPF8
chr155064724150647311-5'-UTR,intron-Distal4.141203.07217HepG2NCBP2
chr155064717150647188-5'-UTR,intron-Distal5.337876.83278K562PRPF8
chr155058167950581777-CDS,intron-Distal,intron-Proximal3.470136.97987K562ZNF622
chr155060188650601923-CDS,intron-Distal,intron-Proximal3.281583.87559K562YBX3
chr155058174550581814-CDS,intron-Distal4.115763.01429K562IGF2BP1
chr155057834550578381-CDS,intron-Distal,intron-Proximal3.603134.24220K562ZNF622
chr155064372950643793-intron-Distal5.098596.76922HepG2PTBP1
chr155064180850641857-intron-Distal3.805263.42844K562KHSRP
chr155064695650647026-intron-Distal3.194063.38183K562NONO
chr155064657950646685-intron-Distal5.055087.08889K562RBM15
chr155064372950643809-intron-Distal5.8273123.97953HepG2PCBP2
chr155064670950646807-intron-Distal3.034924.87047K562NONO
chr155064185750642024-intron-Distal3.049616.88763K562KHSRP
chr155064712250647171-intron-Distal5.8013010.25778K562PRPF8
chr155064372650643853-intron-Distal4.1158114.28161K562ILF3
chr155064672850646828-intron-Distal3.287334.07500HepG2SLTM
chr155064696250647017-intron-Distal4.2711210.03874HepG2DDX3X
chr155064672850646824-intron-Distal4.535617.34858HepG2RBM15
chr155064672150646806-intron-Distal3.125153.91689K562GTF2F1
chr155064659550646694-intron-Distal3.467424.45974HepG2GTF2F1
chr155064659250646675-intron-Distal3.949447.32634HepG2PRPF4
chr155064660450646693-intron-Distal4.288774.69797HepG2DGCR8
chr155064669450646770-intron-Distal6.371428.80038K562GEMIN5
chr155064660250646679-intron-Distal3.031393.13759K562XRN2
chr155064690050646970-intron-Distal3.197543.34231K562RBM15
chr155061080250610925-intron-Distal4.086003.33944K562MATR3
chr155064672850646807-intron-Distal3.965155.33662K562SLTM
chr155064652150646656-intron-Distal4.575865.93974HepG2UPF1
chr155064658850646653-intron-Distal3.791194.12910K562DROSHA
chr155064379350643858-intron-Distal3.748373.89405HepG2PTBP1
chr155064380950643862-intron-Distal7.1900030.24932HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GABPB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GABPB1 is not available on ENCORE database.

  • 74 RBPs can affect the levels of GABPB1.  








The Knockdown/knockout RNA-Seq assay for GABPB1 is not available on ENCORE database.





74 RBPs can affect the gene expression of GABPB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GABPB1ENSG00000104064.12362.44660522.54880-0.527802.407701.52840HepG2ABCF1
GABPB1ENSG00000104064.12366.27320561.83660-0.617203.657003.05700HepG2AKAP1
GABPB1ENSG00000104064.12314.15520464.87570-0.565403.377002.51000HepG2ASCC1
GABPB1ENSG00000104064.12316.47010448.86780-0.504202.586701.68270HepG2BCCIP
GABPB1ENSG00000104064.12245.32160390.00710-0.668803.910702.85980HepG2BCLAF1
GABPB1ENSG00000104064.12682.48180506.742800.429402.856902.24920HepG2BOP1
GABPB1ENSG00000104064.12400.78710557.04450-0.475003.489102.63690HepG2CALR
GABPB1ENSG00000104064.12430.25510625.61790-0.540103.006401.98820HepG2CCAR1
GABPB1ENSG00000104064.12261.82900410.35920-0.648306.206105.28180HepG2CKAP4
GABPB1ENSG00000104064.12264.92670378.65080-0.515301.963601.32470HepG2CNOT7
GABPB1ENSG00000104064.12274.40870465.19810-0.761505.725604.76950HepG2CPSF6
GABPB1ENSG00000104064.12276.03000379.59850-0.459603.537902.60960HepG2DDX19B
GABPB1ENSG00000104064.12409.73660538.20350-0.393501.974401.43760HepG2DDX3X
GABPB1ENSG00000104064.12259.86800441.34270-0.764104.975903.97580HepG2DDX55
GABPB1ENSG00000104064.12360.37930528.27310-0.551802.270801.38790HepG2DDX59
GABPB1ENSG00000104064.12318.82880483.02180-0.599304.206902.96780HepG2DDX5
GABPB1ENSG00000104064.12187.23890444.44760-1.2471011.7011010.53360HepG2EIF2S1
GABPB1ENSG00000104064.12374.09540610.25010-0.706006.133304.94260HepG2EIF4G2
GABPB1ENSG00000104064.12213.39500466.03580-1.126904.924803.57480HepG2FTO
GABPB1ENSG00000104064.12320.92800459.70880-0.518502.868702.19160HepG2G3BP1
GABPB1ENSG00000104064.12257.52120527.28530-1.033908.535707.45250HepG2GPKOW
GABPB1ENSG00000104064.12249.93290395.44960-0.662004.333303.54830HepG2HNRNPA1
GABPB1ENSG00000104064.12251.03740439.85700-0.809106.260205.25010HepG2HNRNPC
GABPB1ENSG00000104064.12364.71450485.55910-0.412903.016102.26940HepG2HNRNPF
GABPB1ENSG00000104064.12425.80750588.18900-0.466104.621503.76770HepG2HNRNPL
GABPB1ENSG00000104064.12270.57780503.20290-0.895107.679506.69060HepG2HNRNPLL
GABPB1ENSG00000104064.12243.15320436.94950-0.845609.919308.82870HepG2HNRNPU
GABPB1ENSG00000104064.121093.99900660.600800.727705.989104.75780HepG2LARP4
GABPB1ENSG00000104064.12370.63870510.24840-0.461202.446801.84960HepG2NCBP2
GABPB1ENSG00000104064.12491.59320640.28770-0.381302.843702.06930HepG2NOL12
GABPB1ENSG00000104064.12269.43670405.33010-0.589202.304601.31740HepG2NONO
GABPB1ENSG00000104064.12334.15160446.22410-0.417302.171901.50670HepG2NSUN2
GABPB1ENSG00000104064.12347.70170456.56720-0.393002.667102.06910HepG2PCBP1
GABPB1ENSG00000104064.12293.83750377.51010-0.361502.140501.45240HepG2PRPF4
GABPB1ENSG00000104064.12168.08410340.39390-1.018007.351706.11070HepG2PRPF8
GABPB1ENSG00000104064.12351.71930464.58560-0.401502.685202.14490HepG2PTBP1
GABPB1ENSG00000104064.12258.70240611.21550-1.2404017.0968015.78860HepG2PUF60
GABPB1ENSG00000104064.12467.47990648.83780-0.473005.229704.46760HepG2PUM1
GABPB1ENSG00000104064.12485.40750648.36040-0.417603.112902.40180HepG2PUM2
GABPB1ENSG00000104064.12357.64670503.13330-0.492403.545202.85030HepG2QKI
GABPB1ENSG00000104064.12294.28510402.37680-0.451302.371401.62630HepG2RPS2
GABPB1ENSG00000104064.12266.98640389.12730-0.543504.281403.51120HepG2SAFB2
GABPB1ENSG00000104064.12480.19100586.07190-0.287502.032101.41340HepG2SLBP
GABPB1ENSG00000104064.12330.90170453.79560-0.455603.812703.07800HepG2SMN1
GABPB1ENSG00000104064.12321.71080554.16870-0.784604.585003.56950HepG2SNRNP70
GABPB1ENSG00000104064.12358.86260477.04400-0.410702.990102.27130HepG2SRSF7
GABPB1ENSG00000104064.12855.98550606.026100.498103.002002.47240HepG2SSB
GABPB1ENSG00000104064.12295.58860439.33060-0.571703.038902.33420HepG2SUPV3L1
GABPB1ENSG00000104064.12358.08810490.60770-0.454302.689801.97410HepG2TARDBP
GABPB1ENSG00000104064.12220.90040424.60630-0.942709.573708.74120HepG2TIAL1
GABPB1ENSG00000104064.12261.87660428.37170-0.710007.304906.46470HepG2TRIM56
GABPB1ENSG00000104064.12279.29890595.07690-1.091303.289902.21200HepG2U2AF2
GABPB1ENSG00000104064.12284.23600403.20930-0.504403.845503.04240HepG2UPF1
GABPB1ENSG00000104064.12290.04580432.47340-0.576303.392702.59490HepG2XRN2
GABPB1ENSG00000104064.121165.99630443.451301.3946051.3238049.73330HepG2ZNF622
GABPB1ENSG00000104064.121712.538701062.059600.6892016.2423014.98680K562AGGF1
GABPB1ENSG00000104064.121481.710501167.091800.344203.016201.97770K562AKAP8
GABPB1ENSG00000104064.121568.828901105.133200.505405.751104.78930K562AKAP8L
GABPB1ENSG00000104064.121696.871601236.783500.456204.080803.39540K562AQR
GABPB1ENSG00000104064.121432.331801159.573400.304703.258802.26160K562ATP5C1
GABPB1ENSG00000104064.121021.81860679.024500.589505.332904.11150K562BOP1
GABPB1ENSG00000104064.121392.459001120.603800.313303.718802.97870K562DDX47
GABPB1ENSG00000104064.121585.880701189.127100.415305.980404.62040K562DKC1
GABPB1ENSG00000104064.121194.93150752.783300.666504.471203.52840K562G3BP2
GABPB1ENSG00000104064.12528.26600686.91600-0.378902.502301.93160K562HNRNPC
GABPB1ENSG00000104064.12698.51560930.04370-0.413004.226003.11300K562HNRNPU
GABPB1ENSG00000104064.121468.255701147.250400.355802.745301.95330K562HSPD1
GABPB1ENSG00000104064.121851.221401172.780400.658404.676603.55390K562KIF1C
GABPB1ENSG00000104064.121590.665901122.673600.502603.417802.18360K562MAK16
GABPB1ENSG00000104064.121707.59830920.893700.890805.258803.90710K562NAA15
GABPB1ENSG00000104064.12479.49920618.97700-0.368402.499001.74000K562POLR2G
GABPB1ENSG00000104064.12748.24850586.037200.352402.014501.36930K562PRPF8
GABPB1ENSG00000104064.12429.73790615.89250-0.519203.434002.41210K562PSIP1
GABPB1ENSG00000104064.121384.911301738.65350-0.328203.667102.56130K562PUM2
GABPB1ENSG00000104064.122555.639901095.903001.2215027.9563026.21390K562PUS1
GABPB1ENSG00000104064.122001.446201067.863500.906208.897807.86070K562RBM15
GABPB1ENSG00000104064.12806.41680596.923400.433902.638801.84350K562RPS19
GABPB1ENSG00000104064.121562.42830955.419000.709503.101601.77390K562SNRNP200
GABPB1ENSG00000104064.12657.95050859.12570-0.384902.875501.79710K562SRSF4
GABPB1ENSG00000104064.12726.49700566.610100.358502.740401.47180K562SSB
GABPB1ENSG00000104064.12765.96380945.99390-0.304603.055202.30150K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GABPB1 is not available on ENCORE database.





11 RBPs can affect the splicing of GABPB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGABPB1ENSG00000104064.12chr15-505951255059532050593453505935655059616250596330-0.313000.000000.00000excludedHepG2U2AF1
SEGABPB1ENSG00000104064.12chr15-5057447550574588505707385057098150578264505783800.052000.001820.04984includedK562AKAP8L
SEGABPB1ENSG00000104064.12chr15-505951255059532050593453505935655059616250596330-0.115000.000000.00000excludedK562AQR
SEGABPB1ENSG00000104064.12chr15-505951255059532050593453505935655059616250596330-0.080000.000160.00495excludedK562U2AF1
A3SSGABPB1ENSG00000104064.12chr15-5059298550593225505929855059309950593417505935120.067000.000280.00219longerK562AQR
A3SSGABPB1ENSG00000104064.12chr15-505816795058186550581679505818625059298550593099-0.107000.001650.01085shorterK562AQR
A3SSGABPB1ENSG00000104064.12chr15-505816795058186550581679505818625059298550593099-0.338000.000000.00000shorterHepG2CDC40
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.276000.000000.00087longerK562RBM22
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.237000.000000.00002longerK562AQR
A5SSGABPB1ENSG00000104064.12chr15-505934175059356550593453505935655059298550593099-0.223000.000430.01974shorterHepG2U2AF2
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.314000.001370.09276longerHepG2RBM22
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.208000.000740.06549longerK562PRPF8
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.225000.000330.03994longerK562EFTUD2
A5SSGABPB1ENSG00000104064.12chr15-505934175059356550593453505935655059298550593099-0.217000.000080.03562shorterHepG2HNRNPL
A5SSGABPB1ENSG00000104064.12chr15-5059341750593565505934535059356550592985505930990.270000.000000.00016longerK562SRSF1
A5SSGABPB1ENSG00000104064.12chr15-505934175059356550593453505935655059298550593099-0.306000.000060.08171shorterHepG2FUS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GABPB1 is not avaliable on ENCORE database.