FOXO3

General Information

Gene Name       : FOXO3
Gene ID             : ENSG00000118689.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FOXO3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FOXO3ENSG00000118689.141.401.561.48ENCSR000AEF
HepG2FOXO3ENSG00000118689.148.818.958.88ENCSR985KAT
K562FOXO3ENSG00000118689.147.986.297.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FOXO3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FOXO3 RNA is bound by 22 proteins.  







eCLIP assay for FOXO3 is not avaliable on ENCORE database.





22 proteins are bound to FOXO3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6109003611109003721+3'-UTR3.500153.88925HepG2UPF1
chr6109003169109003275+3'-UTR5.4826114.94017K562UPF1
chr6109001235109001315+3'-UTR4.139054.08466HepG2IGF2BP1
chr6109005848109005899+3'-UTR5.462704.37209K562PUM2
chr6109003134109003252+3'-UTR4.869004.20997HepG2UPF1
chr6109003612109003685+3'-UTR3.7897719.23093K562UPF1
chr6109001148109001220+3'-UTR4.177793.57526HepG2IGF2BP1
chr6109003263109003356+3'-UTR5.3908110.58401HepG2QKI
chr6109001668109001756+3'-UTR4.463693.64119HepG2UPF1
chr6109003685109003726+3'-UTR5.284408.41097K562UPF1
chr6108883013108883066+CDS,intron-Proximal3.223453.05161HepG2PPIG
chr6108888407108888492+intron-Distal4.294074.70434HepG2RBFOX2
chr6108932737108932838+intron-Distal3.213834.30679K562KHSRP
chr6108921255108921335+intron-Distal5.262376.37964HepG2ILF3
chr6108930560108930588+intron-Distal3.919644.94813HepG2HNRNPM
chr6108934975108935045+intron-Distal3.122297.08259HepG2SUGP2
chr6108883842108883896+intron-Distal3.651444.83336HepG2FAM120A
chr6108934362108934405+intron-Distal3.273353.00129HepG2SUGP2
chr6108934629108934685+intron-Distal3.759405.66122HepG2MATR3
chr6108930588108930627+intron-Distal5.108486.79824HepG2HNRNPM
chr6108883433108883525+intron-Distal3.191235.04644HepG2HNRNPUL1
chr6108904700108904742+intron-Distal4.233666.98528HepG2HNRNPM
chr6108883410108883516+intron-Distal4.136407.76457HepG2GTF2F1
chr6108904656108904700+intron-Distal3.770423.39857HepG2HNRNPM
chr6108934974108935026+intron-Distal3.077943.63322HepG2MATR3
chr6108934262108934295+intron-Distal3.977533.54208HepG2SUGP2
chr6108904661108904740+intron-Distal3.334713.59509K562HNRNPM
chr6108883254108883309+intron-Distal3.237973.16890HepG2XRN2
chr6108888586108888673+intron-Distal3.906808.81766HepG2XPO5
chr6108905112108905142+intron-Distal4.182385.28337HepG2HNRNPM
chr6108883132108883238+intron-Distal4.977776.22015HepG2FASTKD2
chr6108905142108905208+intron-Distal5.3730917.63532HepG2HNRNPM
chr6108883409108883537+intron-Distal4.791026.92157K562CSTF2T
chr6108972486108972576+intron-Distal4.095253.83958HepG2QKI
chr6108905155108905195+intron-Distal4.453303.04182K562HNRNPM
chr6108934633108934687+intron-Distal3.854485.78794HepG2SUGP2
chr6108905542108905572+intron-Distal3.116153.11000HepG2HNRNPM
chr6108883220108883262+intron-Distal4.369473.90256HepG2PRPF4
chr6108935408108935459+intron-Distal4.900988.16055HepG2SUGP2
chr6108914603108914684+intron-Distal5.029409.81157HepG2HNRNPC
chr6108883221108883317+intron-Distal3.062857.62135HepG2CSTF2T
chr6108883407108883516+intron-Distal4.078067.41476HepG2RBFOX2
chr6108904585108904619+intron-Distal4.426895.02084HepG2HNRNPM
chr6108936928108937033+intron-Distal3.885496.73852HepG2SUGP2
chr6108993960108994018+intron-Distal3.209436.48384HepG2PTBP1
chr6108934774108934845+intron-Distal3.638553.02234K562KHSRP
chr6108935372108935439+intron-Distal3.546736.29905HepG2MATR3
chr6108934578108934617+intron-Distal4.369674.78128HepG2SUGP2
chr6108883213108883321+intron-Distal3.335773.50009K562CSTF2T
chr6108951658108951734+intron-Distal4.270424.31871HepG2HNRNPM
chr6108884489108884586+intron-Distal4.541803.83958HepG2QKI
chr6108935301108935428+intron-Distal3.754885.98773K562KHSRP
chr6108934178108934244+intron-Distal3.503056.55984HepG2SUGP2
chr6108902330108902362+intron-Distal4.247673.97018HepG2HNRNPM
chr6108936137108936208+intron-Distal3.261065.36060HepG2SUGP2
chr6108934424108934520+intron-Distal3.8969410.74597HepG2SUGP2
chr6108906593108906705+intron-Distal3.036965.96019HepG2HNRNPC
chr6108894674108894827+intron-Distal3.220093.10946HepG2SFPQ
chr6108883397108883498+intron-Distal3.7178610.97733HepG2FAM120A
chr6108905675108905719+intron-Distal3.728935.28337HepG2HNRNPM
chr6108883382108883505+intron-Distal3.188335.28242HepG2PRPF4
chr6108934423108934506+intron-Distal4.587865.42395HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FOXO3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FOXO3 is not available on ENCORE database.

  • 103 RBPs can affect the levels of FOXO3.  








The Knockdown/knockout RNA-Seq assay for FOXO3 is not available on ENCORE database.





103 RBPs can affect the gene expression of FOXO3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FOXO3ENSG00000118689.10966.450802555.72220-1.4030025.7792024.34630HepG2AKAP1
FOXO3ENSG00000118689.101184.572001658.64300-0.485602.580501.57550HepG2AKAP8
FOXO3ENSG00000118689.10700.42930962.50260-0.458602.806101.86200HepG2BCCIP
FOXO3ENSG00000118689.10870.357601423.19520-0.7095018.1417016.76460HepG2CKAP4
FOXO3ENSG00000118689.10991.500801546.80720-0.641604.072503.13740HepG2CNOT7
FOXO3ENSG00000118689.10985.096001185.37420-0.267002.370301.43140HepG2YBX3
FOXO3ENSG00000118689.10972.867901316.51290-0.436407.314606.06690HepG2DDX19B
FOXO3ENSG00000118689.10956.136101280.32660-0.421203.809703.02610HepG2DDX21
FOXO3ENSG00000118689.101239.649802448.07770-0.9817015.6269014.26180HepG2DDX3X
FOXO3ENSG00000118689.10662.65780946.34180-0.514103.433602.58250HepG2DDX55
FOXO3ENSG00000118689.101399.59930915.259000.612703.205202.15560HepG2DDX59
FOXO3ENSG00000118689.10656.587701153.69050-0.8132020.5106018.88690HepG2DNAJC2
FOXO3ENSG00000118689.10954.653801321.37370-0.469002.200301.37630HepG2EEF2
FOXO3ENSG00000118689.10733.926401101.74530-0.586103.105801.93380HepG2EFTUD2
FOXO3ENSG00000118689.10955.222901210.22910-0.341402.928801.72280HepG2EIF2S2
FOXO3ENSG00000118689.101352.882402233.98920-0.723607.858606.78330HepG2EIF4A3
FOXO3ENSG00000118689.102264.638402005.744600.175001.979801.45280HepG2ETF1
FOXO3ENSG00000118689.10580.92500958.57290-0.722504.919403.32190HepG2FAM120A
FOXO3ENSG00000118689.101134.358001596.13430-0.492703.058801.88540HepG2FUS
FOXO3ENSG00000118689.101562.470502254.38080-0.528905.334704.39450HepG2FXR1
FOXO3ENSG00000118689.101110.022802091.06920-0.9137012.6350011.26780HepG2G3BP1
FOXO3ENSG00000118689.101515.377102220.19880-0.551005.866304.55810HepG2G3BP2
FOXO3ENSG00000118689.10616.80500913.57440-0.566704.336003.54620HepG2GPKOW
FOXO3ENSG00000118689.101319.792001549.01780-0.231002.215801.37000HepG2HNRNPA2B1
FOXO3ENSG00000118689.10860.561401307.05430-0.603006.794105.74480HepG2HNRNPC
FOXO3ENSG00000118689.101308.39760997.734700.391005.171404.22900HepG2HNRNPF
FOXO3ENSG00000118689.101223.128402117.86290-0.7920012.0841010.72470HepG2HNRNPK
FOXO3ENSG00000118689.101512.49830871.847100.7947010.202209.08110HepG2HNRNPLL
FOXO3ENSG00000118689.10813.794101111.47580-0.449704.574803.38440HepG2HNRNPM
FOXO3ENSG00000118689.10779.431101298.41130-0.7363016.1335014.76480HepG2HNRNPU
FOXO3ENSG00000118689.101345.02250982.485000.453002.936402.19230HepG2IGF2BP1
FOXO3ENSG00000118689.101534.624702125.45520-0.469904.322003.49430HepG2IGF2BP2
FOXO3ENSG00000118689.101039.924001326.28060-0.350905.028304.06460HepG2ILF2
FOXO3ENSG00000118689.101029.282401474.52090-0.518603.760802.33420HepG2KHDRBS1
FOXO3ENSG00000118689.101634.749402137.97750-0.387202.370501.45280HepG2KHSRP
FOXO3ENSG00000118689.10823.614501194.41830-0.536303.403702.14600HepG2LARP7
FOXO3ENSG00000118689.101402.727602255.16950-0.685008.132307.01970HepG2MAGOH
FOXO3ENSG00000118689.101202.721602267.72980-0.9149012.1988010.93910HepG2MATR3
FOXO3ENSG00000118689.10853.643501303.72620-0.610907.954406.64840HepG2MSI2
FOXO3ENSG00000118689.101726.112402321.09730-0.427303.461802.75710HepG2NCBP2
FOXO3ENSG00000118689.101332.009701671.31860-0.327403.436402.58760HepG2NOL12
FOXO3ENSG00000118689.101034.29160773.108600.419803.106402.31510HepG2NSUN2
FOXO3ENSG00000118689.101097.433401285.17890-0.227802.060701.32040HepG2PARN
FOXO3ENSG00000118689.10525.36150887.13520-0.755805.051503.40710HepG2PKM
FOXO3ENSG00000118689.101064.386001994.23370-0.9058027.4509026.07410HepG2PTBP1
FOXO3ENSG00000118689.10833.425601449.88510-0.7988021.3102019.89620HepG2PUS1
FOXO3ENSG00000118689.101613.441201950.27240-0.273502.515201.69410HepG2RBM15
FOXO3ENSG00000118689.102170.463401676.449800.372505.490404.82300HepG2RBM22
FOXO3ENSG00000118689.101013.969801440.21760-0.506302.807501.80920HepG2RBM27
FOXO3ENSG00000118689.101429.115802219.34550-0.6350014.8817013.81460HepG2NELFE
FOXO3ENSG00000118689.101527.967902067.10050-0.436007.605806.65820HepG2RECQL
FOXO3ENSG00000118689.101351.629601074.787500.330502.520301.86360HepG2RPLP0
FOXO3ENSG00000118689.10670.907301043.75010-0.637603.773403.06570HepG2RPS19
FOXO3ENSG00000118689.101001.285601328.36230-0.407802.091201.38970HepG2RPS2
FOXO3ENSG00000118689.101002.429001553.83550-0.632304.878003.81420HepG2RPS3A
FOXO3ENSG00000118689.10835.873301156.28040-0.468107.231206.26090HepG2SAFB2
FOXO3ENSG00000118689.10747.335101047.72970-0.487402.302201.44130HepG2SERBP1
FOXO3ENSG00000118689.101382.341002013.39700-0.542503.971503.15720HepG2SF3A3
FOXO3ENSG00000118689.101537.28620862.917100.8330012.2499010.86410HepG2SF3B1
FOXO3ENSG00000118689.101238.395602076.15740-0.7454019.6679018.32420HepG2SF3B4
FOXO3ENSG00000118689.10937.365101348.39780-0.5246010.479309.35820HepG2SMN1
FOXO3ENSG00000118689.102632.838401893.521000.4754011.4501010.61900HepG2SRFBP1
FOXO3ENSG00000118689.101155.559002167.09850-0.9072030.0539028.86320HepG2SRSF1
FOXO3ENSG00000118689.101233.31830980.237400.331203.745102.95300HepG2SRSF7
FOXO3ENSG00000118689.101311.851301791.50010-0.449608.615807.61940HepG2SUCLG1
FOXO3ENSG00000118689.101429.400801789.81390-0.324403.057802.18370HepG2TIA1
FOXO3ENSG00000118689.10713.269601261.57130-0.8227014.7377013.74510HepG2TIAL1
FOXO3ENSG00000118689.10923.625501272.93240-0.462807.110206.27870HepG2TRIM56
FOXO3ENSG00000118689.102066.270901378.097600.584306.639205.67970HepG2U2AF1
FOXO3ENSG00000118689.10430.27500556.50600-0.371101.975201.33370HepG2UCHL5
FOXO3ENSG00000118689.101223.794701785.58070-0.5450010.868509.65220HepG2UPF1
FOXO3ENSG00000118689.101536.525701835.28710-0.256302.796401.74480HepG2UTP18
FOXO3ENSG00000118689.101242.190901723.89980-0.472808.121707.18320HepG2UTP3
FOXO3ENSG00000118689.101156.321401603.60050-0.471802.832501.76430HepG2XRCC6
FOXO3ENSG00000118689.10731.72220927.36110-0.341801.946501.33040HepG2XRN2
FOXO3ENSG00000118689.10893.405901096.71650-0.295802.599101.94490HepG2ZC3H8
FOXO3ENSG00000118689.101564.958001963.78940-0.327504.905504.23000HepG2ZNF622
FOXO3ENSG00000118689.10996.780301277.71820-0.358202.975601.94630K562AKAP8
FOXO3ENSG00000118689.10945.873901209.96100-0.355202.828702.16760K562AKAP8L
FOXO3ENSG00000118689.101755.93730907.788600.9517016.3384015.07050K562AQR
FOXO3ENSG00000118689.10950.820801269.51590-0.417004.998403.73090K562ATP5C1
FOXO3ENSG00000118689.101122.530601389.68390-0.308002.828101.63740K562CCDC124
FOXO3ENSG00000118689.101240.52780717.584900.789605.266703.74460K562CNOT7
FOXO3ENSG00000118689.10735.97490524.516100.488604.271503.29610K562CPSF6
FOXO3ENSG00000118689.102034.353301444.005400.494406.503005.02210K562CELF1
FOXO3ENSG00000118689.101005.783201364.31310-0.439903.991102.21950K562DDX19B
FOXO3ENSG00000118689.101588.850501022.159000.6363013.1104011.80260K562DDX47
FOXO3ENSG00000118689.101006.089401302.08600-0.372104.441703.29430K562DKC1
FOXO3ENSG00000118689.10913.04080538.374800.762006.186404.25950K562EEF2
FOXO3ENSG00000118689.10562.65560321.577900.807004.244002.97240K562EIF3A
FOXO3ENSG00000118689.10987.45130758.281900.380903.073702.21030K562EIF4A3
FOXO3ENSG00000118689.101411.836501174.282500.265702.203301.36030K562EIF4G2
FOXO3ENSG00000118689.10648.91310445.532700.542403.763502.41970K562FKBP4
FOXO3ENSG00000118689.10617.33050452.430700.448202.783601.86650K562FTO
FOXO3ENSG00000118689.10941.88060725.945000.375603.144801.99790K562HNRNPA1
FOXO3ENSG00000118689.10819.80150513.156400.675807.270206.34700K562HNRNPC
FOXO3ENSG00000118689.101112.43450795.541200.483608.300707.10680K562NSUN2
FOXO3ENSG00000118689.10998.71870784.934400.347402.510901.58060K562PCBP2
FOXO3ENSG00000118689.101924.81250952.554201.0147015.4330013.51850K562PCBP3
FOXO3ENSG00000118689.101354.33530730.618700.8903016.4530014.58160K562POLR2G
FOXO3ENSG00000118689.10606.95400820.05190-0.434103.212302.31640K562PPIG
FOXO3ENSG00000118689.10679.63890506.153400.425102.563501.84120K562PRPF8
FOXO3ENSG00000118689.10520.82140857.19390-0.718809.373708.20040K562PTBP1
FOXO3ENSG00000118689.102082.017701281.212900.700409.823108.26030K562PUF60
FOXO3ENSG00000118689.10655.780501200.04210-0.8718011.7754010.70310K562PUS1
FOXO3ENSG00000118689.10993.805001169.18340-0.234501.810201.31260K562RBM15
FOXO3ENSG00000118689.10280.48560419.78920-0.581704.019302.82360K562RCC2
FOXO3ENSG00000118689.10506.57720683.89660-0.433004.025302.13110K562RPS10
FOXO3ENSG00000118689.10731.25840515.524800.504203.027002.17210K562RPS19
FOXO3ENSG00000118689.10976.63390785.077400.314902.995402.14990K562SF3A3
FOXO3ENSG00000118689.10637.86720476.338200.421202.297101.41920K562SF3B1
FOXO3ENSG00000118689.101117.74680804.336100.474607.343205.89440K562SRPK2
FOXO3ENSG00000118689.10648.81870840.37140-0.373202.891802.17230K562SRSF1
FOXO3ENSG00000118689.101053.62720831.593800.341302.953601.38140K562SRSF9
FOXO3ENSG00000118689.101429.112201117.861900.354303.423201.75220K562SUCLG1
FOXO3ENSG00000118689.10669.30200489.977600.449802.620701.63350K562SUPV3L1
FOXO3ENSG00000118689.10981.07000736.544500.413502.806801.59690K562UTP3
FOXO3ENSG00000118689.101147.37870721.777900.668609.031407.41260K562WDR3
FOXO3ENSG00000118689.101029.50670750.613800.455706.664505.40500K562WDR43
FOXO3ENSG00000118689.101339.066901022.495000.389003.531002.53450K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FOXO3 is not available on ENCORE database.






No RBPs affect the alternative splcing events of FOXO3 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for FOXO3 is not avaliable on ENCORE database.