EXOC2

General Information

Gene Name       : EXOC2
Gene ID             : ENSG00000112685.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOC2ENSG00000112685.1313.0513.2913.17ENCSR000AEF
HepG2EXOC2ENSG00000112685.1313.9716.4115.19ENCSR985KAT
K562EXOC2ENSG00000112685.1314.6116.3115.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOC2 RNA is bound by 27 proteins.  







eCLIP assay for EXOC2 is not avaliable on ENCORE database.





27 proteins are bound to EXOC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6576850576894-3'-UTR,CDS,intron-Distal,intron-Proximal3.598113.03452HepG2U2AF2
chr6485983486050-3'-UTR,intron-Distal3.751553.10834HepG2CSTF2
chr6486180486248-3'-UTR,intron-Distal3.754886.47483K562PUM2
chr6485227485289-3'-UTR,intron-Distal5.557478.21523HepG2SUB1
chr6693018693105-5'-UTR,intron-Distal4.792646.43970K562FXR2
chr6693024693092-5'-UTR,intron-Distal4.815375.38689K562FMR1
chr6693011693107-5'-UTR,intron-Distal4.236447.22925K562DDX3X
chr6692972693058-5'-UTR,intron-Distal4.1916810.26986HepG2PRPF8
chr6692948693099-5'-UTR,intron-Distal3.375944.09778HepG2NCBP2
chr6556482556554-CDS,intron-Distal,intron-Proximal4.154285.20093K562DDX24
chr6556483556538-CDS,intron-Distal,intron-Proximal3.413635.15500HepG2BCLAF1
chr6592474592519-CDS,intron-Distal3.741304.93978HepG2BCLAF1
chr6549197549255-CDS,intron-Distal3.302113.31745K562ZNF622
chr6637662637733-CDS,intron-Distal,intron-Proximal5.320229.06713HepG2PRPF8
chr6598049598109-CDS,intron-Distal4.019203.69113K562LIN28B
chr6532468532504-CDS,intron-Distal,intron-Proximal3.611844.46864HepG2BCLAF1
chr6598859598933-CDS,intron-Distal,intron-Proximal5.8638016.18483K562LIN28B
chr6556478556540-CDS,intron-Distal,intron-Proximal3.589064.22563K562UCHL5
chr6592484592564-CDS,intron-Distal3.760343.38114HepG2GRWD1
chr6556479556563-CDS,intron-Distal,intron-Proximal4.029167.55042HepG2PPIG
chr6592470592565-CDS,intron-Distal4.021916.06308HepG2PPIG
chr6619433619488-CDS,intron-Distal3.922595.36555HepG2BCLAF1
chr6592519592558-CDS,intron-Distal3.484023.28366HepG2BCLAF1
chr6617741617823-CDS,intron-Distal4.273044.96452K562YBX3
chr6556327556394-intron-Distal,intron-Proximal4.116373.45799HepG2U2AF2
chr6684140684253-intron-Distal3.924905.76537HepG2PCBP2
chr6520823520904-intron-Distal4.098053.94684HepG2CSTF2T
chr6519193519256-intron-Distal4.166084.61649HepG2CSTF2T
chr6664223664285-intron-Distal4.346054.48623K562EXOSC5
chr6655863655920-intron-Distal3.930773.47315HepG2CSTF2
chr6664378664423-intron-Distal4.235283.30696K562EXOSC5
chr6601102601266-intron-Distal5.277314.96498HepG2GRSF1
chr6520746520816-intron-Distal4.131614.19345HepG2CSTF2T
chr6567659567753-intron-Distal4.394163.98095HepG2HNRNPL
chr6662664662703-intron-Distal3.903796.10949K562EXOSC5
chr6541044541113-intron-Distal3.892573.04224HepG2SUGP2
chr6683168683238-intron-Distal4.030843.27946HepG2HNRNPM
chr6506990507131-intron-Distal4.453665.79092K562TARDBP
chr6534677534748-intron-Distal3.848023.39864HepG2SUGP2
chr6542509542583-intron-Distal3.960803.47525K562MATR3
chr6542967543025-intron-Distal3.839983.29248HepG2SUGP2
chr6542503542573-intron-Distal4.239324.10336HepG2SUGP2
chr6520931521018-intron-Distal5.703795.03841K562AATF
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOC2 is not available on ENCORE database.

  • 51 RBPs can affect the levels of EXOC2.  








The Knockdown/knockout RNA-Seq assay for EXOC2 is not available on ENCORE database.





51 RBPs can affect the gene expression of EXOC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOC2ENSG00000112685.9991.40060757.823400.387504.731703.97640HepG2ACO1
EXOC2ENSG00000112685.91521.84560905.727700.748607.356606.53430HepG2AKAP1
EXOC2ENSG00000112685.9382.77490688.19920-0.846308.631807.47590HepG2CPSF6
EXOC2ENSG00000112685.91079.58900867.634300.315201.820601.30190HepG2DDX3X
EXOC2ENSG00000112685.9632.96750948.50360-0.583505.647004.50640HepG2EIF4G2
EXOC2ENSG00000112685.91100.54300778.628000.499103.138502.32440HepG2FIP1L1
EXOC2ENSG00000112685.9594.23300780.16650-0.392802.177801.60590HepG2GPKOW
EXOC2ENSG00000112685.9768.39310975.71120-0.344603.250302.47830HepG2HNRNPF
EXOC2ENSG00000112685.9717.33280914.32990-0.350104.067103.26230HepG2HNRNPL
EXOC2ENSG00000112685.9485.45210673.40960-0.472204.828604.04570HepG2HNRNPU
EXOC2ENSG00000112685.9740.01480960.80560-0.376702.944302.19920HepG2IGF2BP1
EXOC2ENSG00000112685.9468.48780803.62460-0.778506.638505.69310HepG2MATR3
EXOC2ENSG00000112685.9489.77600684.30280-0.482504.847604.07990HepG2PCBP1
EXOC2ENSG00000112685.9910.69700696.349900.387104.403403.74800HepG2PTBP1
EXOC2ENSG00000112685.9671.21740950.04590-0.501204.850004.08830HepG2PUF60
EXOC2ENSG00000112685.9995.65550754.065600.400903.944103.21620HepG2QKI
EXOC2ENSG00000112685.91505.317401121.948400.424005.472804.80610HepG2RBM22
EXOC2ENSG00000112685.91002.01620684.400200.549906.020405.06060HepG2RBM25
EXOC2ENSG00000112685.91102.48810774.932200.508506.960706.17130HepG2NELFE
EXOC2ENSG00000112685.9863.91110721.813700.259202.136601.58540HepG2RECQL
EXOC2ENSG00000112685.9891.31270724.907200.298002.678802.09580HepG2SF3B4
EXOC2ENSG00000112685.9852.72460699.340600.286002.707602.06830HepG2SMN1
EXOC2ENSG00000112685.91994.333901267.191400.6542016.9280015.96450HepG2SRFBP1
EXOC2ENSG00000112685.91243.02780756.680100.7160014.4590013.55830HepG2SRSF1
EXOC2ENSG00000112685.91056.41610792.900800.413902.318301.41240HepG2SRSF3
EXOC2ENSG00000112685.9732.196201100.20810-0.587509.791108.94100HepG2SSB
EXOC2ENSG00000112685.9840.04410680.227400.304302.489201.95370HepG2TAF15
EXOC2ENSG00000112685.9524.37650660.19440-0.332302.703602.14410HepG2TRIM56
EXOC2ENSG00000112685.9963.08430699.001300.462306.210805.23180HepG2UPF1
EXOC2ENSG00000112685.9484.80060674.36410-0.476103.340202.54860HepG2XRN2
EXOC2ENSG00000112685.9900.75350768.767400.228502.041601.55290HepG2ZNF622
EXOC2ENSG00000112685.91141.582101535.52950-0.427706.271305.46990K562AGGF1
EXOC2ENSG00000112685.91345.308801687.31320-0.326802.652301.69600K562AKAP8
EXOC2ENSG00000112685.91294.252101597.78770-0.304001.894601.35000K562AKAP8L
EXOC2ENSG00000112685.91175.426302082.66130-0.8252012.9875011.85110K562AQR
EXOC2ENSG00000112685.9732.38400941.92740-0.363002.863702.06770K562CPSF6
EXOC2ENSG00000112685.9684.02810867.84660-0.343402.506101.50790K562CSTF2
EXOC2ENSG00000112685.92367.808501775.857300.414907.434606.43620K562DDX47
EXOC2ENSG00000112685.9785.302601044.52270-0.411502.979702.03190K562EFTUD2
EXOC2ENSG00000112685.91126.787101442.45270-0.356304.167903.31220K562EIF2S2
EXOC2ENSG00000112685.9840.969101058.66870-0.332102.598601.37240K562EXOSC5
EXOC2ENSG00000112685.91480.355801922.25480-0.376903.800202.91890K562GRSF1
EXOC2ENSG00000112685.9611.07330975.84460-0.675307.932906.96970K562HNRNPC
EXOC2ENSG00000112685.9686.23200982.46500-0.517703.842202.73440K562HNRNPM
EXOC2ENSG00000112685.91037.924501575.07760-0.6017010.340608.63510K562HNRNPU
EXOC2ENSG00000112685.9435.920301398.44460-1.6817049.1214045.74300K562MATR3
EXOC2ENSG00000112685.9993.344201246.81670-0.327902.512201.58160K562PCBP2
EXOC2ENSG00000112685.91076.935601346.62510-0.322402.009701.30200K562PCBP3
EXOC2ENSG00000112685.91186.584601558.54150-0.393402.894601.30600K562PKM
EXOC2ENSG00000112685.9656.71120874.95810-0.414002.743601.84320K562PSIP1
EXOC2ENSG00000112685.92241.233202780.86040-0.311204.274203.07420K562PUM2
EXOC2ENSG00000112685.91031.880401305.58380-0.339402.623001.80620K562RBM22
EXOC2ENSG00000112685.9577.16450756.79890-0.390902.609701.62310K562SRFBP1
EXOC2ENSG00000112685.9674.75260984.19320-0.544604.124702.86390K562SUPV3L1
EXOC2ENSG00000112685.91084.324701302.90860-0.264902.058801.36010K562TIA1
EXOC2ENSG00000112685.91934.738602346.15620-0.278202.266101.49770K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOC2 is not available on ENCORE database.





10 RBPs can affect the splicing of EXOC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOC2ENSG00000112685.9chr6-689138689212637700637861693018693111-0.150000.005820.08507excludedK562SRSF1
SEEXOC2ENSG00000112685.9chr6-5345075345805324685326105491745492910.222000.000000.00000includedK562MATR3
SEEXOC2ENSG00000112685.9chr6-6891386892126377006378616930186931110.222000.000130.02332includedHepG2HNRNPM
SEEXOC2ENSG00000112685.9chr6-6891386892126377006378616930186931110.146000.002600.03129includedHepG2U2AF2
SEEXOC2ENSG00000112685.9chr6-6475006476666377006378616930186931110.068000.010990.08749includedK562AQR
SEEXOC2ENSG00000112685.9chr6-689138689212679142679514693018693111-0.478000.000790.01405excludedK562PUS1
SEEXOC2ENSG00000112685.9chr6-6891386892126377006378616930186931110.211000.000180.01247includedHepG2SFPQ
SEEXOC2ENSG00000112685.9chr6-689138689212637700637861693018693111-0.115000.001520.08661excludedK562HNRNPUL1
SEEXOC2ENSG00000112685.9chr6-689138689212637700637861693018693111-0.080000.001370.03569excludedK562AGGF1
SEEXOC2ENSG00000112685.9chr6-6891386892126377006378616930186931110.181000.005550.07528includedK562HNRNPC
MXEEXOC2ENSG00000112685.9chr6-657162657250689138689212637700637861693018693111-0.755000.002270.036212includedK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOC2 is not avaliable on ENCORE database.