ECHS1

General Information

Gene Name       : ECHS1
Gene ID             : ENSG00000127884.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ECHS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ECHS1ENSG00000127884.422.4538.8330.64ENCSR000AEF
HepG2ECHS1ENSG00000127884.490.6885.7988.24ENCSR985KAT
K562ECHS1ENSG00000127884.448.4945.8247.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ECHS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ECHS1 RNA is bound by 26 proteins.  







eCLIP assay for ECHS1 is not avaliable on ENCORE database.





26 proteins are bound to ECHS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10135176113135176175-3'-UTR,intron-Distal3.242516.22791HepG2LARP4
chr10135176030135176101-3'-UTR,intron-Distal5.8234012.69138K562UPF1
chr10135176099135176166-3'-UTR,intron-Distal4.6609411.61205HepG2AKAP1
chr10135176164135176301-3'-UTR,intron-Distal4.2766520.16150HepG2UPF1
chr10135176112135176156-3'-UTR,intron-Distal3.6244411.37584K562YBX3
chr10135176200135176272-3'-UTR,intron-Distal4.7684313.58361HepG2AKAP1
chr10135176038135176092-3'-UTR,intron-Distal5.7742614.89968HepG2UPF1
chr10135176165135176184-3'-UTR,intron-Distal3.280526.82055K562YBX3
chr10135176184135176202-3'-UTR,intron-Distal3.378907.65028K562YBX3
chr10135176175135176316-3'-UTR,intron-Distal3.3655015.60380HepG2LARP4
chr10135176092135176164-3'-UTR,intron-Distal4.8876822.32576HepG2UPF1
chr10135176172135176299-3'-UTR,intron-Distal3.074307.18980K562PABPC4
chr10135176207135176295-3'-UTR,intron-Distal3.726417.18938HepG2SUB1
chr10135176101135176157-3'-UTR,intron-Distal4.013519.71169K562UPF1
chr10135176211135176295-3'-UTR,intron-Distal3.240405.40646K562RBM15
chr10135176170135176287-3'-UTR,intron-Distal3.458373.28107HepG2PABPN1
chr10135176316135176374-3'-UTR,intron-Distal4.264718.02139HepG2LARP4
chr10135176196135176277-3'-UTR,intron-Distal4.3391910.83280HepG2DDX55
chr10135176358135176437-3'-UTR,CDS,intron-Distal3.925103.05298K562GRWD1
chr10135176022135176099-3'-UTR,intron-Distal3.907869.96705HepG2AKAP1
chr10135176157135176197-3'-UTR,intron-Distal3.252894.96603K562UPF1
chr10135186763135186847-5'-UTR,CDS,intron-Distal4.2006616.30612K562DDX3X
chr10135186749135186866-5'-UTR,CDS,intron-Distal4.0224420.74206HepG2DDX3X
chr10135184023135184071-CDS,intron-Distal,intron-Proximal6.1739816.41790HepG2PRPF8
chr10135176395135176437-CDS,intron-Distal4.816155.35719HepG2GRWD1
chr10135180464135180547-CDS,intron-Distal,intron-Proximal4.452598.61283HepG2SF3B4
chr10135180431135180493-CDS,intron-Distal4.181904.69290HepG2RPS3
chr10135179430135179488-CDS,intron-Distal,intron-Proximal4.475049.76577HepG2PRPF8
chr10135184133135184169-CDS,intron-Distal3.473938.74043K562YBX3
chr10135180468135180498-CDS,intron-Distal,intron-Proximal3.683124.91603HepG2LIN28B
chr10135186748135186763-CDS,intron-Distal4.080519.06301K562DDX3X
chr10135179577135179645-CDS,intron-Distal,intron-Proximal5.7676114.41773HepG2SF3A3
chr10135182426135182460-CDS,intron-Distal,intron-Proximal3.761745.47334HepG2LIN28B
chr10135184169135184203-CDS,intron-Distal4.1265023.36078K562YBX3
chr10135179499135179600-CDS,intron-Distal,intron-Proximal5.2091918.04982K562LIN28B
chr10135184203135184210-CDS,intron-Distal3.481999.18871K562YBX3
chr10135186714135186758-CDS,intron-Distal3.683716.55814HepG2PRPF8
chr10135184210135184220-CDS,intron-Distal3.218108.30608K562YBX3
chr10135180405135180427-CDS,intron-Distal4.515934.67689HepG2PPIG
chr10135184066135184108-CDS,intron-Distal4.291323.73614HepG2RPS3
chr10135184081135184114-CDS,intron-Distal4.377433.99162HepG2DDX3X
chr10135182383135182441-CDS,intron-Distal,intron-Proximal5.7302610.09256HepG2PRPF8
chr10135179535135179596-CDS,intron-Distal3.225565.65286HepG2LIN28B
chr10135179553135179600-CDS,intron-Distal,intron-Proximal3.514628.36460HepG2BUD13
chr10135182426135182448-CDS,intron-Distal,intron-Proximal4.355473.47885K562LIN28B
chr10135180467135180498-CDS,intron-Distal,intron-Proximal4.543664.13050K562LIN28B
chr10135184240135184261-CDS,intron-Distal3.924636.59200K562DDX3X
chr10135182363135182433-CDS,intron-Distal,intron-Proximal4.874885.69951K562AQR
chr10135180347135180394-CDS,intron-Distal,intron-Proximal3.9107413.31241HepG2PRPF8
chr10135180464135180539-CDS,intron-Distal,intron-Proximal5.861688.26501K562SF3B4
chr10135186298135186460-intron-Distal3.545744.61945HepG2HNRNPK
chr10135180690135180752-intron-Distal3.873563.47043HepG2KHSRP
chr10135186276135186431-intron-Distal3.540928.93510HepG2RBFOX2
chr10135186389135186430-intron-Distal4.570184.42259HepG2DDX59
chr10135176438135176500-intron-Distal4.4879010.59756HepG2SF3A3
chr10135180663135180747-intron-Distal3.857187.37475HepG2U2AF2
chr10135180347135180393-intron-Distal,intron-Proximal4.521533.93614HepG2AQR
chr10135180159135180302-intron-Distal,intron-Proximal3.743833.06084HepG2HNRNPK
chr10135186301135186443-intron-Distal6.2214214.35812HepG2PCBP2
chr10135180385135180392-intron-Distal,intron-Proximal3.587105.35619K562AQR
chr10135182160135182215-intron-Distal4.910579.86390HepG2XPO5
chr10135180350135180365-intron-Distal,intron-Proximal4.416117.92018K562AQR
chr10135180365135180385-intron-Distal,intron-Proximal3.668935.83621K562AQR
chr10135186568135186646-intron-Distal4.473626.69976HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ECHS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ECHS1 is not available on ENCORE database.

  • 110 RBPs can affect the levels of ECHS1.  








The Knockdown/knockout RNA-Seq assay for ECHS1 is not available on ENCORE database.





110 RBPs can affect the gene expression of ECHS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ECHS1ENSG00000127884.4852.106401206.42090-0.501604.916903.52840HepG2AATF
ECHS1ENSG00000127884.41243.168901555.91850-0.323704.520603.77960HepG2ACO1
ECHS1ENSG00000127884.41503.398503163.91580-1.0735016.5709015.38080HepG2AKAP1
ECHS1ENSG00000127884.41962.248902617.81370-0.415903.609102.71430HepG2ASCC1
ECHS1ENSG00000127884.43486.676702487.122900.487305.180204.14050HepG2CIRBP
ECHS1ENSG00000127884.41259.40120982.313500.358402.519801.48970HepG2CSTF2
ECHS1ENSG00000127884.42106.696802501.25400-0.247703.674902.84060HepG2DAZAP1
ECHS1ENSG00000127884.41703.834201438.929100.243702.609701.79700HepG2DDX19B
ECHS1ENSG00000127884.41119.036001563.87400-0.482903.945403.03770HepG2DDX55
ECHS1ENSG00000127884.4595.56660866.89990-0.541602.394601.48560HepG2DDX59
ECHS1ENSG00000127884.41537.563001065.970100.528405.400504.03440HepG2DDX5
ECHS1ENSG00000127884.41749.590902603.70890-0.573605.284304.45640HepG2DDX6
ECHS1ENSG00000127884.41434.390301065.150500.429302.533601.64810HepG2EEF2
ECHS1ENSG00000127884.41588.489502502.70250-0.655807.735606.78050HepG2EIF2S1
ECHS1ENSG00000127884.41530.607702693.01390-0.815108.006406.86620HepG2EIF4B
ECHS1ENSG00000127884.41535.948702467.84040-0.6841014.1138012.51190HepG2EIF4G1
ECHS1ENSG00000127884.42143.095002692.33360-0.329205.414404.62180HepG2ETF1
ECHS1ENSG00000127884.41022.818601268.33070-0.310402.432301.35820HepG2FASTKD2
ECHS1ENSG00000127884.4807.750601274.57580-0.658005.441104.39320HepG2FIP1L1
ECHS1ENSG00000127884.41245.798101584.68930-0.347103.046602.22400HepG2FUBP3
ECHS1ENSG00000127884.4933.777201361.95240-0.544503.479302.22490HepG2FUS
ECHS1ENSG00000127884.42106.520002790.85520-0.405803.464002.69510HepG2FXR1
ECHS1ENSG00000127884.41587.999402588.69170-0.705008.247907.12840HepG2G3BP1
ECHS1ENSG00000127884.41131.07230865.301400.386302.240301.66040HepG2GPKOW
ECHS1ENSG00000127884.41403.642601038.052400.435204.130803.36450HepG2HNRNPA1
ECHS1ENSG00000127884.41699.042002621.83520-0.625908.399207.23480HepG2HNRNPK
ECHS1ENSG00000127884.41749.006202278.38060-0.381507.749206.67050HepG2HNRNPL
ECHS1ENSG00000127884.4902.327901146.99170-0.346104.001103.28350HepG2HNRNPU
ECHS1ENSG00000127884.41540.018501156.887100.412604.556503.64670HepG2IGF2BP1
ECHS1ENSG00000127884.41966.699902631.26470-0.420003.584802.82640HepG2IGF2BP2
ECHS1ENSG00000127884.41013.078902469.66610-1.285607.250105.70700HepG2IGF2BP3
ECHS1ENSG00000127884.41214.804801422.20630-0.227402.612401.62020HepG2KIF1C
ECHS1ENSG00000127884.4801.419701031.41930-0.364002.988702.14860HepG2MSI2
ECHS1ENSG00000127884.4657.59710866.11990-0.397403.242301.92520HepG2NAA15
ECHS1ENSG00000127884.41474.933902480.25080-0.7498016.7554014.97390HepG2NOL12
ECHS1ENSG00000127884.41763.848702558.72650-0.536705.338304.34590HepG2PABPC4
ECHS1ENSG00000127884.41432.608402600.11730-0.8599029.1983027.58340HepG2PCBP1
ECHS1ENSG00000127884.41738.758701289.187800.431502.364901.40190HepG2PCBP2
ECHS1ENSG00000127884.41246.587501023.028000.285002.113201.46210HepG2PPIL4
ECHS1ENSG00000127884.41734.049902645.80750-0.6096014.6897013.62290HepG2PTBP1
ECHS1ENSG00000127884.41740.016102513.47270-0.5306015.2921014.12970HepG2PUM1
ECHS1ENSG00000127884.41763.682002511.59000-0.510007.778906.68010HepG2PUM2
ECHS1ENSG00000127884.41938.287701584.780800.290404.154003.42580HepG2PUS1
ECHS1ENSG00000127884.41683.442002865.28110-0.7673018.5469017.13010HepG2QKI
ECHS1ENSG00000127884.4767.131601243.80050-0.697203.979003.13910HepG2RAVER1
ECHS1ENSG00000127884.4813.822201382.76860-0.7648013.0561011.40490HepG2RBM15
ECHS1ENSG00000127884.41381.716502250.28080-0.7036016.4458015.39690HepG2RBM22
ECHS1ENSG00000127884.41749.089702600.50000-0.572208.692407.54580HepG2RBM25
ECHS1ENSG00000127884.41770.978401278.083500.470503.699102.47220HepG2RCC2
ECHS1ENSG00000127884.42115.000002944.45420-0.4773010.012109.10180HepG2NELFE
ECHS1ENSG00000127884.41941.073602742.49600-0.4986010.964709.86170HepG2RECQL
ECHS1ENSG00000127884.4661.11310841.36050-0.347802.615702.01730HepG2RPS19
ECHS1ENSG00000127884.41364.23340921.978500.565203.934802.98190HepG2RPS3A
ECHS1ENSG00000127884.4778.105601193.07420-0.616605.527904.45120HepG2RRP9
ECHS1ENSG00000127884.41983.882201365.334700.539002.183801.58380HepG2SF3A3
ECHS1ENSG00000127884.41298.13190817.319500.667407.669806.54580HepG2SF3B1
ECHS1ENSG00000127884.42134.450802754.46410-0.367906.364805.52910HepG2SF3B4
ECHS1ENSG00000127884.41459.07500909.425200.681904.575603.56160HepG2SNRNP70
ECHS1ENSG00000127884.42120.793802541.58840-0.261103.961903.39370HepG2SRFBP1
ECHS1ENSG00000127884.41916.063502337.82980-0.287003.743703.03630HepG2SRSF5
ECHS1ENSG00000127884.41530.738102339.12930-0.6117016.2985015.15950HepG2SRSF9
ECHS1ENSG00000127884.43352.563802206.663800.6033018.0703017.00280HepG2SSB
ECHS1ENSG00000127884.42149.962202658.67940-0.306405.085504.28540HepG2SUCLG1
ECHS1ENSG00000127884.41096.027501556.73040-0.506204.349703.52910HepG2SUPV3L1
ECHS1ENSG00000127884.41570.836002584.46430-0.7183013.4088012.31160HepG2TAF15
ECHS1ENSG00000127884.41214.473402374.57470-0.9673023.3932021.04140HepG2TIA1
ECHS1ENSG00000127884.41376.048701114.581500.303902.667902.17520HepG2TIAL1
ECHS1ENSG00000127884.4598.766701090.23760-0.8646011.189809.90410HepG2U2AF1
ECHS1ENSG00000127884.4398.631901064.56890-1.417103.455902.34920HepG2U2AF2
ECHS1ENSG00000127884.41752.318802448.61560-0.482704.019402.99960HepG2UBE2L3
ECHS1ENSG00000127884.4732.32240919.55250-0.328502.118201.45490HepG2UCHL5
ECHS1ENSG00000127884.41442.210901210.848500.252202.478901.81170HepG2UPF1
ECHS1ENSG00000127884.4866.177501223.60660-0.498402.696401.45510HepG2XRCC5
ECHS1ENSG00000127884.42081.304101532.432900.441603.443902.63950HepG2XRN2
ECHS1ENSG00000127884.41707.993501331.694000.358904.669804.00640HepG2ZNF622
ECHS1ENSG00000127884.41181.54500793.403200.574408.990708.04300K562AGGF1
ECHS1ENSG00000127884.41171.52210871.786600.426203.138102.07720K562AKAP8
ECHS1ENSG00000127884.41013.98120825.561300.296501.898001.35300K562AKAP8L
ECHS1ENSG00000127884.41101.867701858.81190-0.7544010.788009.74150K562AQR
ECHS1ENSG00000127884.41048.88980866.192300.276002.186101.38140K562ATP5C1
ECHS1ENSG00000127884.4370.96220499.45070-0.429102.649401.62590K562CCAR1
ECHS1ENSG00000127884.41242.91010948.195300.390403.832402.41410K562CCDC124
ECHS1ENSG00000127884.4649.056801046.73800-0.689503.815602.53330K562CNOT7
ECHS1ENSG00000127884.41172.82230888.430400.400604.490703.33750K562DKC1
ECHS1ENSG00000127884.4613.68660871.15540-0.505404.163603.02350K562EFTUD2
ECHS1ENSG00000127884.41219.828501475.15820-0.274202.769002.05050K562EIF2S2
ECHS1ENSG00000127884.4875.00170667.902300.389503.457502.57310K562EIF3G
ECHS1ENSG00000127884.4956.64450773.461000.306602.062001.32640K562FIP1L1
ECHS1ENSG00000127884.4501.34300686.22420-0.452902.413801.37310K562FKBP4
ECHS1ENSG00000127884.41202.60390977.179200.299402.797702.18940K562FXR1
ECHS1ENSG00000127884.4417.91790605.57930-0.535103.034402.28790K562G3BP2
ECHS1ENSG00000127884.4791.590201003.00280-0.341503.126701.91160K562GLRX3
ECHS1ENSG00000127884.4515.75160789.53430-0.614305.872705.03450K562HNRNPC
ECHS1ENSG00000127884.4517.21070705.27300-0.447402.989401.79870K562HNRNPF
ECHS1ENSG00000127884.4997.609201535.07460-0.6218010.653608.92530K562HNRNPU
ECHS1ENSG00000127884.4322.20750504.33890-0.646404.839902.88260K562KHDRBS1
ECHS1ENSG00000127884.41108.17840876.164500.338802.421101.65640K562KIF1C
ECHS1ENSG00000127884.4269.89210415.52540-0.622603.141402.13850K562KRR1
ECHS1ENSG00000127884.4343.06250475.00970-0.469502.819801.93390K562METAP2
ECHS1ENSG00000127884.4798.214901054.52730-0.401704.866003.81570K562MTPAP
ECHS1ENSG00000127884.4888.377001171.67080-0.399306.139405.08780K562NSUN2
ECHS1ENSG00000127884.4673.297901005.60710-0.578703.276501.91620K562PABPC1
ECHS1ENSG00000127884.4530.91730884.68180-0.736706.941105.62140K562PCBP3
ECHS1ENSG00000127884.4540.98300678.58580-0.326902.070801.37840K562POLR2G
ECHS1ENSG00000127884.41159.44000878.144400.400803.254802.35260K562PPIG
ECHS1ENSG00000127884.41235.79120994.679200.313002.646601.99450K562PTBP1
ECHS1ENSG00000127884.41913.439002270.28310-0.246702.741001.78660K562PUM2
ECHS1ENSG00000127884.41248.43790818.807100.608406.395905.60940K562PUS1
ECHS1ENSG00000127884.4381.97080577.76330-0.597002.727201.32450K562RAVER1
ECHS1ENSG00000127884.41059.13760797.740500.408804.081003.37770K562RBM15
ECHS1ENSG00000127884.4980.620501156.14560-0.237602.057701.34720K562SF3A3
ECHS1ENSG00000127884.4338.59260462.80690-0.450902.162901.31420K562SF3B1
ECHS1ENSG00000127884.4410.74700550.15970-0.421602.655901.41980K562SLBP
ECHS1ENSG00000127884.4522.33080832.10410-0.671802.489501.34950K562SNRNP200
ECHS1ENSG00000127884.4444.43590612.56390-0.462902.410401.46970K562SRFBP1
ECHS1ENSG00000127884.4955.746801184.49660-0.309603.616902.56290K562SRPK2
ECHS1ENSG00000127884.41457.67330975.149800.579907.634306.46720K562SRSF1
ECHS1ENSG00000127884.4589.96960772.40030-0.388703.194401.55990K562SRSF9
ECHS1ENSG00000127884.4529.23490820.71660-0.633005.108903.69060K562SUPV3L1
ECHS1ENSG00000127884.4458.55800631.09150-0.460703.175901.46010K562TBRG4
ECHS1ENSG00000127884.4482.17530723.69890-0.585804.540303.25960K562TRIM56
ECHS1ENSG00000127884.4413.76010586.83710-0.504203.077801.91420K562U2AF1
ECHS1ENSG00000127884.4409.83870606.12930-0.564605.273804.17040K562U2AF2
ECHS1ENSG00000127884.4663.38200868.66500-0.389002.577001.59860K562UCHL5
ECHS1ENSG00000127884.4819.093101063.03720-0.376103.231002.29020K562WDR3
ECHS1ENSG00000127884.4890.169901105.43860-0.312503.556402.60420K562WDR43
ECHS1ENSG00000127884.41543.271002094.18090-0.440404.881603.68540K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ECHS1 is not available on ENCORE database.





2 RBPs can affect the splicing of ECHS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSECHS1ENSG00000127884.4chr10-1351840631351843081351840631351842611351867491351871930.058000.000000.00001longerK562AQR
A3SSECHS1ENSG00000127884.4chr10-1351824261351825531351824261351825261351834071351835350.062000.000000.00000longerK562AQR
A5SSECHS1ENSG00000127884.4chr10-135178161135178229135178202135178229135175983135176437-0.071000.000000.00002shorterK562RBM22
A5SSECHS1ENSG00000127884.4chr10-135178161135178229135178202135178229135175983135176437-0.051000.000010.00235shorterHepG2RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ECHS1 is not avaliable on ENCORE database.