CDV3

General Information

Gene Name       : CDV3
Gene ID             : ENSG00000091527.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CDV3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CDV3ENSG00000091527.15155.01145.47150.24ENCSR000AEF
HepG2CDV3ENSG00000091527.1554.0896.8675.47ENCSR985KAT
K562CDV3ENSG00000091527.1580.6580.8380.74ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq CDV3-BGKcLV28-K562ENCSR944PAOCDV3K562ReleasedENCSR220DTX   CRISPRKD% = 50.7,53.9
knockdown followed by RNA-seq CDV3-BGHcLV29-HepG2ENCSR875UMYCDV3HepG2ReleasedENCSR462MFN   CRISPRKD% = 57.2,76.4






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
CDV3ENCAB772KPZA304-660A1Released, ENCODE4BGHcLV29-15, Released, ENCODE4BGKcLV28-15, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CDV3K562CRISPRENCSR944PAOENCSR220DTXCDV3-BGKcLV28-15,CDV3-BGKcLV28-16NT-BGKcLV28-1,NT-BGKcLV28-250.7,53.9ReleasedENCODE4
CDV3HepG2CRISPRENCSR875UMYENCSR462MFNCDV3-BGHcLV29-15,CDV3-BGHcLV29-16NT-BGHcLV29-1,NT-BGHcLV29-257.2,76.4ReleasedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
CDV3Product_ID: A304-660A
Lot_ID: 1
Source: Bethyl Labs
Target Name: CDV3-human		 CDV3-HEPG2-CRISPR-A304-660A.png<br>Caption: Western blot following CRISPR against CDV3 in HepG2 whole cell lysate using CDV3 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CDV3. CDV3 protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
 Bethyl_A304-660A_1_CDV3.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the CDV3 specific antibody, A304-660A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the CDV3-specific antibody, A304-660A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 CDV3-K562-CRISPR-A304-660A.png<br>Caption: Western blot following CRISPR against CDV3 in K562 whole cell lysate using CDV3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CDV3. CDV3 protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for CDV3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CDV3 RNA is bound by 28 proteins.  







eCLIP assay for CDV3 is not avaliable on ENCORE database.





28 proteins are bound to CDV3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3133307914133308019+3'-UTR3.1973922.43632K562FAM120A
chr3133307064133307106+3'-UTR,intron-Distal,intron-Proximal4.243174.43679K562IGF2BP1
chr3133306917133306999+3'-UTR,intron-Distal3.7991210.16905K562IGF2BP2
chr3133307665133307811+3'-UTR3.712305.19069HepG2TIAL1
chr3133308318133308375+3'-UTR3.968958.04798K562UPF1
chr3133306911133307032+3'-UTR,intron-Distal3.691808.48612HepG2IGF2BP1
chr3133306923133307032+3'-UTR,intron-Distal4.670626.18721HepG2IGF2BP3
chr3133307685133307737+3'-UTR4.2214134.29461K562UPF1
chr3133308325133308420+3'-UTR3.225093.04614K562FUS
chr3133308255133308318+3'-UTR3.5992811.90104K562UPF1
chr3133307132133307195+3'-UTR,intron-Proximal5.198706.40308HepG2IGF2BP1
chr3133307712133307786+3'-UTR4.5823043.96313K562FAM120A
chr3133307918133307996+3'-UTR3.0400911.80844K562UPF1
chr3133307242133307312+3'-UTR3.752566.36204K562IGF2BP1
chr3133306999133307044+3'-UTR,intron-Distal4.468678.00923K562IGF2BP2
chr3133307826133307904+3'-UTR3.803558.27558K562LIN28B
chr3133307669133307693+3'-UTR5.234179.05943K562TIA1
chr3133308568133308642+3'-UTR4.180053.79154K562FUS
chr3133307737133307783+3'-UTR3.7369711.61541K562UPF1
chr3133307188133307222+3'-UTR,CDS,intron-Proximal4.727987.30074K562IGF2BP1
chr3133307683133307712+3'-UTR4.4274937.67662K562FAM120A
chr3133307796133307839+3'-UTR3.235708.58981K562FAM120A
chr3133307662133307683+3'-UTR3.9635616.30821K562FAM120A
chr3133306925133307012+3'-UTR,intron-Distal3.653699.65383K562IGF2BP1
chr3133307693133307765+3'-UTR4.4430020.68132K562TIA1
chr3133307684133307712+3'-UTR3.634053.06310K562HNRNPC
chr3133307663133307689+3'-UTR3.372484.08506K562APOBEC3C
chr3133308659133308692+3'-UTR3.685434.24288K562UPF1
chr3133307590133307635+3'-UTR3.957164.32275HepG2FAM120A
chr3133308260133308310+3'-UTR3.019978.09757K562FAM120A
chr3133307665133307754+3'-UTR5.064485.69187HepG2TIA1
chr3133307126133307188+3'-UTR,intron-Proximal5.1614219.57874K562IGF2BP1
chr3133308141133308205+3'-UTR3.329634.77875HepG2SUB1
chr3133307662133307685+3'-UTR3.9130913.90707K562UPF1
chr3133293907133293959+5'-UTR,CDS3.259278.82209K562UCHL5
chr3133293914133293962+5'-UTR,CDS,intron-Proximal3.431555.91405HepG2BCLAF1
chr3133292823133293022+5'-UTR,CDS3.203883.87906HepG2SRSF9
chr3133292714133292900+5'-UTR,CDS3.2519025.10519HepG2DDX3X
chr3133292692133292782+5'-UTR3.362996.90018K562PUM1
chr3133293882133293895+5'-UTR,CDS,intron-Proximal3.004103.59602K562UCHL5
chr3133292782133292896+5'-UTR,CDS3.6195112.33022K562PUM1
chr3133292610133292639+5'-UTR4.821964.86570K562ZNF800
chr3133292699133292803+5'-UTR3.201583.67487HepG2FTO
chr3133293899133293958+5'-UTR,CDS3.602514.24070HepG2GRWD1
chr3133292580133292706+5'-UTR3.075323.94428K562DDX3X
chr3133302845133302902+CDS,intron-Proximal3.074973.07833K562ZNF800
chr3133302920133302995+CDS,intron-Proximal3.7471413.36249K562UCHL5
chr3133305406133305468+CDS,intron-Proximal4.713764.74293HepG2ZNF800
chr3133292891133293006+CDS3.7157113.05358HepG2GRWD1
chr3133292896133293006+CDS3.7381310.58323K562PUM1
chr3133293019133293130+CDS,intron-Distal,intron-Proximal3.597705.89284K562RBM15
chr3133302844133302877+CDS,intron-Proximal4.922596.04243HepG2BCLAF1
chr3133302902133302991+CDS3.047407.13758K562ZNF800
chr3133305500133305565+CDS3.159533.09129HepG2GRWD1
chr3133293035133293135+CDS,intron-Distal,intron-Proximal3.694506.62734HepG2SDAD1
chr3133293093133293167+CDS,intron-Distal,intron-Proximal4.179715.90528HepG2AQR
chr3133302953133302984+CDS3.045873.28855HepG2GRWD1
chr3133293029133293141+CDS,intron-Distal,intron-Proximal3.3775212.79844K562GEMIN5
chr3133305407133305499+CDS,intron-Proximal4.268927.06029HepG2GRWD1
chr3133293006133293112+CDS,intron-Proximal3.2990419.51569K562PUM1
chr3133293008133293125+CDS,intron-Distal,intron-Proximal3.9751412.14691HepG2GRWD1
chr3133302901133302990+CDS3.5326410.92329HepG2BCLAF1
chr3133302833133302901+CDS,intron-Proximal3.367473.22327HepG2AQR
chr3133302863133302920+CDS3.403157.80035K562UCHL5
chr3133292924133293002+CDS3.482757.72566K562ZNF800
chr3133305443133305543+CDS3.525204.84084K562ZNF800
chr3133305571133305684+intron-Distal,intron-Proximal3.633189.84476K562AQR
chr3133305592133305689+intron-Distal,intron-Proximal3.249703.78727K562PRPF8
chr3133293141133293174+intron-Distal,intron-Proximal3.607705.90285HepG2PRPF8
chr3133295241133295305+intron-Distal3.354455.42728HepG2HNRNPM
chr3133305599133305652+intron-Proximal4.079723.56076K562BUD13
chr3133305593133305660+intron-Proximal3.458139.64693HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CDV3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CDV3 is not available on ENCORE database.

  • 92 RBPs can affect the levels of CDV3.  








The Knockdown/knockout RNA-Seq assay for CDV3 is not available on ENCORE database.





92 RBPs can affect the gene expression of CDV3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CDV3ENSG00000091527.114115.686803395.116600.277601.986901.31710HepG2ASCC1
CDV3ENSG00000091527.113180.125503826.62310-0.267002.215101.67400HepG2BOP1
CDV3ENSG00000091527.112227.991802808.81990-0.334203.101401.79860HepG2BUD13
CDV3ENSG00000091527.113154.852204654.72400-0.561104.784603.48740HepG2CCAR1
CDV3ENSG00000091527.114000.949503225.571300.310702.474201.73870HepG2CIRBP
CDV3ENSG00000091527.111699.840003355.45240-0.981109.449608.06960HepG2CNOT7
CDV3ENSG00000091527.112545.527803513.04040-0.464805.167304.25350HepG2CPSF6
CDV3ENSG00000091527.115541.889803989.318200.474102.336201.43920HepG2DDX59
CDV3ENSG00000091527.112094.829202549.97300-0.283603.504502.71990HepG2DNAJC21
CDV3ENSG00000091527.111633.376902527.42740-0.6298020.8339019.19900HepG2DNAJC2
CDV3ENSG00000091527.112803.021902113.957100.406905.009203.60760HepG2EIF3G
CDV3ENSG00000091527.114219.115203716.493500.182902.109901.36270HepG2EIF4G1
CDV3ENSG00000091527.112469.816901984.658200.315403.010402.19370HepG2FUBP3
CDV3ENSG00000091527.112113.435003105.95620-0.555403.892102.57290HepG2GRSF1
CDV3ENSG00000091527.112172.809602713.88460-0.320805.081203.79790HepG2HDGF
CDV3ENSG00000091527.111951.581102863.53690-0.553207.587606.48590HepG2HNRNPC
CDV3ENSG00000091527.113155.178103768.32140-0.256203.602302.79280HepG2HNRNPF
CDV3ENSG00000091527.112863.426003431.59330-0.261105.119904.22600HepG2HNRNPL
CDV3ENSG00000091527.111193.271702844.60560-1.2533062.1948059.70150HepG2HNRNPU
CDV3ENSG00000091527.112917.422103710.73180-0.347004.262503.38050HepG2IGF2BP1
CDV3ENSG00000091527.112305.113502905.67210-0.334007.636506.48260HepG2ILF2
CDV3ENSG00000091527.112877.406603620.22550-0.331302.485601.86340HepG2MAGOH
CDV3ENSG00000091527.114714.414003640.573200.372801.899101.37110HepG2MATR3
CDV3ENSG00000091527.113668.414203063.905600.259702.570101.78890HepG2MSI2
CDV3ENSG00000091527.112271.554603875.92980-0.770906.923405.35650HepG2MTPAP
CDV3ENSG00000091527.111825.278002572.65170-0.495106.125904.32770HepG2NAA15
CDV3ENSG00000091527.112430.066203735.49400-0.6203012.6264011.05380HepG2NOL12
CDV3ENSG00000091527.112662.538203318.92110-0.317902.274001.61440HepG2PABPC4
CDV3ENSG00000091527.113811.608503267.219200.222203.066602.43290HepG2PCBP1
CDV3ENSG00000091527.113504.630802971.366800.238003.155002.33440HepG2PRPF4
CDV3ENSG00000091527.112298.736503565.84660-0.6334010.848509.77210HepG2PUF60
CDV3ENSG00000091527.112569.117302895.33680-0.172502.059901.50990HepG2PUS1
CDV3ENSG00000091527.112600.124303600.52490-0.469608.311907.31720HepG2QKI
CDV3ENSG00000091527.114745.408004166.046600.187802.166101.69270HepG2RBM22
CDV3ENSG00000091527.111882.063302483.03780-0.399802.533101.51920HepG2RCC2
CDV3ENSG00000091527.112538.751703368.26990-0.407902.570701.79900HepG2RPS3A
CDV3ENSG00000091527.112093.260002533.25270-0.275204.411903.63150HepG2SAFB2
CDV3ENSG00000091527.112355.957001858.852000.341802.819101.87130HepG2SERBP1
CDV3ENSG00000091527.113868.061603461.245000.160201.796801.30320HepG2SF3B4
CDV3ENSG00000091527.114883.452603612.797300.4347011.5047010.68240HepG2SRSF1
CDV3ENSG00000091527.112764.070103520.74080-0.349106.600205.69050HepG2SRSF5
CDV3ENSG00000091527.114055.989502939.208900.4645012.3847011.36400HepG2SRSF9
CDV3ENSG00000091527.111949.486302556.30420-0.391004.201603.05480HepG2SUPT6H
CDV3ENSG00000091527.114175.890602545.045400.7143010.142508.98340HepG2SUPV3L1
CDV3ENSG00000091527.114475.467003247.342100.462709.242008.31260HepG2TAF15
CDV3ENSG00000091527.112239.170102764.10130-0.303803.453802.90800HepG2TIAL1
CDV3ENSG00000091527.115346.728103238.180900.7234012.1301010.78580HepG2U2AF1
CDV3ENSG00000091527.111883.619901503.607100.325002.743201.98640HepG2UCHL5
CDV3ENSG00000091527.113577.248602629.785300.443802.731101.47810HepG2XRCC5
CDV3ENSG00000091527.112480.119102932.40940-0.241703.964403.18460HepG2ZC3H8
CDV3ENSG00000091527.114415.658303697.112600.256105.571004.86490HepG2ZNF622
CDV3ENSG00000091527.113372.517803998.97330-0.245801.951401.40000K562AKAP8L
CDV3ENSG00000091527.114371.476205547.36500-0.343703.582902.93200K562AQR
CDV3ENSG00000091527.113137.136303703.20990-0.239302.559201.31290K562BCCIP
CDV3ENSG00000091527.112904.386503578.56980-0.301105.210003.87630K562BCLAF1
CDV3ENSG00000091527.113036.603404258.60880-0.487905.678604.41700K562BOP1
CDV3ENSG00000091527.114987.745706313.87260-0.340105.180803.63340K562CPEB4
CDV3ENSG00000091527.112465.547404528.02570-0.8770023.1276020.81540K562CPSF6
CDV3ENSG00000091527.112152.655602714.87830-0.334804.382703.01360K562CSTF2
CDV3ENSG00000091527.113907.503604554.24410-0.221002.825901.60180K562DDX21
CDV3ENSG00000091527.111880.457402420.54420-0.364205.435002.93480K562DDX24
CDV3ENSG00000091527.111887.686302284.46020-0.275202.485401.50070K562DDX3X
CDV3ENSG00000091527.119853.277106534.614300.5924020.7730019.14270K562DDX47
CDV3ENSG00000091527.112400.949703156.13770-0.394603.597202.54570K562EFTUD2
CDV3ENSG00000091527.113871.128704985.09910-0.364904.172303.31600K562EIF2S2
CDV3ENSG00000091527.112898.647101745.127000.731905.375403.93290K562EIF3A
CDV3ENSG00000091527.114183.069202945.232900.506108.797307.37970K562EIF3G
CDV3ENSG00000091527.114311.835905648.15950-0.389504.326803.25060K562FIP1L1
CDV3ENSG00000091527.113430.920904607.34710-0.425304.707403.58980K562FMR1
CDV3ENSG00000091527.112811.433503905.22400-0.474104.903703.65010K562FTO
CDV3ENSG00000091527.114323.143202481.995700.8005026.9000025.13680K562FXR1
CDV3ENSG00000091527.113774.482802849.668100.405402.662301.97180K562G3BP2
CDV3ENSG00000091527.113170.713704323.07240-0.447205.712004.57520K562GPKOW
CDV3ENSG00000091527.114510.250006643.60210-0.558807.416206.16400K562GRSF1
CDV3ENSG00000091527.111803.158603052.29360-0.759409.189408.15230K562HNRNPC
CDV3ENSG00000091527.114564.308803283.884700.474904.951503.24620K562HNRNPK
CDV3ENSG00000091527.113447.726404219.51080-0.291403.877102.81520K562HNRNPU
CDV3ENSG00000091527.112439.150703287.65810-0.430703.316102.15770K562IGF2BP2
CDV3ENSG00000091527.112712.053303691.56870-0.444803.136002.13430K562KRR1
CDV3ENSG00000091527.114097.815203455.452300.245902.202501.44720K562MAGOH
CDV3ENSG00000091527.112018.262504219.83400-1.0641028.5470025.78180K562METAP2
CDV3ENSG00000091527.113796.723704662.11570-0.296205.650804.52200K562MTPAP
CDV3ENSG00000091527.112497.416203332.39480-0.416102.782301.89600K562NAA15
CDV3ENSG00000091527.114424.654305180.23520-0.227505.674904.66170K562NSUN2
CDV3ENSG00000091527.113364.180704240.84950-0.334102.605901.80130K562PCBP3
CDV3ENSG00000091527.112631.846503252.87510-0.305603.327002.44370K562POLR2G
CDV3ENSG00000091527.115215.686406411.65310-0.297802.668101.86570K562PPIG
CDV3ENSG00000091527.112021.073002736.57940-0.437304.122502.98770K562PSIP1
CDV3ENSG00000091527.114253.422903357.169400.341304.046803.25830K562PTBP1
CDV3ENSG00000091527.113364.233103864.16120-0.199901.956201.44250K562RBM15
CDV3ENSG00000091527.111862.622702496.18870-0.422404.017802.82240K562RCC2
CDV3ENSG00000091527.114106.230903128.777900.392103.372402.46910K562RPS19
CDV3ENSG00000091527.113731.839902898.393700.364504.161602.82280K562SAFB
CDV3ENSG00000091527.114210.174705111.26380-0.279804.323203.32090K562SF3A3
CDV3ENSG00000091527.113450.438602963.734600.219302.071101.33340K562SF3B4
CDV3ENSG00000091527.111867.657702366.38080-0.341502.795201.76490K562SRFBP1
CDV3ENSG00000091527.112423.985503108.14180-0.358703.377502.19820K562SRSF5
CDV3ENSG00000091527.113312.895204064.26400-0.294904.471102.96360K562SRSF7
CDV3ENSG00000091527.115072.660403262.720000.636607.264305.91700K562SYNCRIP
CDV3ENSG00000091527.112592.634203330.88620-0.361503.235202.47070K562TARDBP
CDV3ENSG00000091527.112573.895403212.99980-0.320003.508602.56970K562TIA1
CDV3ENSG00000091527.111884.574402632.20270-0.482004.393303.19410K562TIAL1
CDV3ENSG00000091527.112380.994303147.58860-0.402703.530902.37290K562UCHL5
CDV3ENSG00000091527.114621.242905492.69690-0.249204.379803.49610K562UPF1
CDV3ENSG00000091527.113433.143804699.95390-0.453106.627505.24010K562WDR3
CDV3ENSG00000091527.115665.037104887.223900.213003.566002.61230K562WDR43
CDV3ENSG00000091527.114436.993206249.64060-0.494207.049505.56460K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CDV3 is not available on ENCORE database.





2 RBPs can affect the splicing of CDV3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECDV3ENSG00000091527.11chr3+1333060021333060051333053441333055661333067391333091050.087000.000070.00118includedK562AQR
SECDV3ENSG00000091527.11chr3+133306739133306789133305344133305566133307196133308006-0.201000.000790.01005excludedK562AQR
SECDV3ENSG00000091527.11chr3+133306739133306789133305406133305566133307196133308006-0.355000.000000.00000excludedHepG2SF3A3
A3SSCDV3ENSG00000091527.11chr3+1333053771333055661333054121333055661333028451333029940.687000.000000.00001longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CDV3 is not avaliable on ENCORE database.