BRF1

General Information

Gene Name       : BRF1
Gene ID             : ENSG00000185024.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: BRF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BRF1ENSG00000185024.163.335.964.64ENCSR000AEF
HepG2BRF1ENSG00000185024.1611.739.5610.64ENCSR985KAT
K562BRF1ENSG00000185024.167.625.496.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BRF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • BRF1 RNA is bound by 31 proteins.  







eCLIP assay for BRF1 is not avaliable on ENCORE database.





31 proteins are bound to BRF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14105676380105676574-3'-UTR,intron-Distal,intron-Proximal4.427599.82827HepG2UPF1
chr14105695142105695247-3'-UTR,CDS,intron-Distal,intron-Proximal3.824265.52342HepG2PPIG
chr14105676510105676627-3'-UTR,intron-Distal,intron-Proximal3.147323.02335HepG2LSM11
chr14105675827105675907-3'-UTR,CDS,intron-Distal4.991916.42091K562UPF1
chr14105676416105676551-3'-UTR,intron-Distal,intron-Proximal5.109139.17081HepG2AKAP1
chr14105676466105676574-3'-UTR,intron-Distal,intron-Proximal4.464974.34093HepG2RBM15
chr14105676370105676452-3'-UTR,intron-Distal,intron-Proximal5.5079210.81337K562UPF1
chr14105676763105676853-3'-UTR,intron-Distal4.404045.07111HepG2UPF1
chr14105676573105676739-3'-UTR,intron-Distal,intron-Proximal6.3673017.30102K562UPF1
chr14105676551105676682-3'-UTR,intron-Distal,intron-Proximal3.542917.19520HepG2AKAP1
chr14105714825105714865-5'-UTR,intron-Distal4.028897.86200HepG2SLTM
chr14105714188105714271-5'-UTR,intron-Distal,intron-Proximal6.1213914.67277K562SLTM
chr14105714309105714400-5'-UTR,intron-Distal,intron-Proximal4.8303313.36902HepG2SLTM
chr14105715528105715630-5'-UTR,intron-Distal5.0238015.66634HepG2SLTM
chr14105692958105693089-5'-UTR,CDS,intron-Distal,intron-Proximal3.357203.84771K562ZNF622
chr14105714322105714387-5'-UTR,intron-Distal,intron-Proximal4.268753.28264K562YWHAG
chr14105707998105708100-5'-UTR,intron-Distal3.930163.94652K562FUS
chr14105715638105715722-5'-UTR,intron-Distal4.253378.77491K562SLTM
chr14105714310105714411-5'-UTR,intron-Distal,intron-Proximal6.5358321.28944K562SLTM
chr14105714557105714613-5'-UTR,intron-Distal4.096463.27946HepG2HNRNPM
chr14105688129105688243-5'-UTR,CDS,intron-Distal,intron-Proximal3.379143.12941K562UCHL5
chr14105715531105715597-5'-UTR,intron-Distal6.2325814.67277K562SLTM
chr14105707786105707929-5'-UTR,intron-Distal,intron-Proximal4.711233.99130HepG2FAM120A
chr14105708009105708080-5'-UTR,intron-Distal3.789905.08142K562SLTM
chr14105688105105688160-5'-UTR,CDS,intron-Distal,intron-Proximal3.969123.60441HepG2GRWD1
chr14105713681105713716-5'-UTR,intron-Distal3.797884.21638K562SLTM
chr14105707814105707877-5'-UTR,intron-Distal,intron-Proximal3.437933.84914K562SLTM
chr14105714141105714278-5'-UTR,intron-Distal,intron-Proximal4.3058815.31144HepG2SLTM
chr14105713667105713727-5'-UTR,intron-Distal4.066563.83566K562YWHAG
chr14105713608105713647-5'-UTR,intron-Distal,intron-Proximal4.748676.11055K562SLTM
chr14105685464105685559-5'-UTR,CDS,intron-Distal,intron-Proximal3.344553.95937K562UCHL5
chr14105692961105693095-5'-UTR,CDS,intron-Distal,intron-Proximal3.914255.35682HepG2GRWD1
chr14105713694105713707-5'-UTR,intron-Distal4.706783.51211HepG2SLTM
chr14105707831105707891-5'-UTR,intron-Distal,intron-Proximal4.964075.22630HepG2SLTM
chr14105686401105686467-5'-UTR,CDS,intron-Distal,intron-Proximal4.310414.13746HepG2PPIG
chr14105766776105766915-CDS,intron-Distal,intron-Proximal4.399288.98365HepG2PPIG
chr14105684045105684138-CDS,intron-Distal,intron-Proximal3.103955.08732HepG2PPIG
chr14105683968105684053-CDS,intron-Distal,intron-Proximal4.973957.33003K562UCHL5
chr14105692956105692972-CDS,intron-Distal,intron-Proximal4.7430310.92835HepG2PRPF8
chr14105683942105684138-CDS,intron-Distal,intron-Proximal3.349626.78413K562ZNF622
chr14105683984105684044-CDS,intron-Distal4.187843.71570HepG2BCLAF1
chr14105683915105684032-CDS,intron-Distal,intron-Proximal3.822954.13746HepG2PPIG
chr14105677456105677562-CDS,intron-Distal,intron-Proximal4.141696.81876K562UPF1
chr14105677565105677630-CDS,intron-Distal3.349213.42164K562UPF1
chr14105722812105722886-CDS,intron-Distal,intron-Proximal3.144944.36737HepG2PRPF8
chr14105692564105692617-CDS,intron-Distal,intron-Proximal4.752464.02817HepG2PRPF8
chr14105722759105722878-CDS,intron-Distal,intron-Proximal4.114143.49003K562PRPF8
chr14105678391105678508-CDS,intron-Distal,intron-Proximal3.706153.09957HepG2AQR
chr14105685359105685392-CDS,intron-Distal,intron-Proximal3.594053.67894HepG2AQR
chr14105684043105684135-CDS,intron-Distal3.810443.22063K562TRA2A
chr14105684041105684139-CDS,intron-Distal,intron-Proximal3.416534.45064HepG2GRWD1
chr14105678407105678421-intron-Distal,intron-Proximal4.945565.26064K562AQR
chr14105737299105737356-intron-Distal4.894733.62238HepG2MATR3
chr14105686397105686406-intron-Distal,intron-Proximal4.002793.96535HepG2AQR
chr14105698727105698778-intron-Distal4.643375.94008HepG2HNRNPM
chr14105710720105710779-intron-Distal3.655213.13435HepG2STAU2
chr14105678219105678296-intron-Distal3.560246.64595HepG2RBFOX2
chr14105686355105686395-intron-Distal,intron-Proximal4.967669.85896K562AQR
chr14105678421105678450-intron-Distal,intron-Proximal4.992115.65342K562AQR
chr14105689672105689748-intron-Distal3.596825.89614HepG2HNRNPM
chr14105707521105707582-intron-Distal,intron-Proximal3.815753.02711K562EWSR1
chr14105681107105681168-intron-Distal4.451315.15063HepG2CSTF2T
chr14105677961105678048-intron-Distal3.893933.63122HepG2PRPF4
chr14105686351105686387-intron-Distal,intron-Proximal5.248726.03362HepG2AQR
chr14105736022105736122-intron-Distal3.112983.28007HepG2NKRF
chr14105750438105750535-intron-Distal4.167504.51309K562HNRNPM
chr14105716485105716551-intron-Distal3.994087.64085K562SLTM
chr14105737314105737405-intron-Distal4.735786.48639K562MATR3
chr14105678368105678433-intron-Distal,intron-Proximal3.233433.26275K562BUD13
chr14105677821105677908-intron-Distal4.6848611.95397HepG2RBFOX2
chr14105678506105678562-intron-Distal,intron-Proximal4.097563.98427HepG2SF3B4
chr14105677958105678047-intron-Distal4.060019.72085HepG2RBFOX2
chr14105681048105681152-intron-Distal3.956093.11728K562FAM120A
chr14105686395105686406-intron-Distal,intron-Proximal4.392347.15298K562AQR
chr14105737169105737251-intron-Distal3.785723.06347K562NONO
chr14105680068105680113-intron-Distal3.898413.16310HepG2CSTF2T
chr14105677821105677910-intron-Distal4.060548.39483K562RBFOX2
chr14105681690105681773-intron-Distal3.458364.82429K562TARDBP
chr14105718767105718844-intron-Distal,intron-Proximal4.739114.48002K562AQR
chr14105715417105715482-intron-Distal4.9013116.82235HepG2SLTM
chr14105686360105686398-intron-Distal,intron-Proximal3.870906.04280HepG2PRPF8
chr14105692919105692956-intron-Distal,intron-Proximal4.5883613.26139HepG2PRPF8
chr14105677937105678037-intron-Distal4.747306.34807K562RBFOX2
chr14105681115105681165-intron-Distal5.014926.10540K562EIF4G2
chr14105715425105715479-intron-Distal5.450879.34978K562SLTM
chr14105746054105746137-intron-Distal4.593615.72853HepG2HNRNPM
chr14105750993105751052-intron-Distal4.358863.97018HepG2HNRNPM
chr14105689748105689834-intron-Distal5.7747523.81608HepG2HNRNPM
chr14105737294105737375-intron-Distal3.322323.00914HepG2PTBP1
chr14105689673105689748-intron-Distal4.727655.04680K562HNRNPM
chr14105698727105698787-intron-Distal3.364794.07903K562EWSR1
chr14105745989105746054-intron-Distal4.344864.38558HepG2HNRNPM
chr14105713221105713300-intron-Distal5.452898.73743HepG2SLTM
chr14105681664105681740-intron-Distal6.1368914.49571K562EIF4G2
chr14105698723105698781-intron-Distal3.046276.07808K562UCHL5
chr14105682654105682724-intron-Distal5.262666.58769K562EIF4G2
chr14105723640105723704-intron-Distal3.225933.77567K562NONO
chr14105683370105683461-intron-Distal,intron-Proximal3.445624.14880HepG2CSTF2T
chr14105717968105718013-intron-Distal3.394203.84914K562SLTM
chr14105692645105692727-intron-Distal,intron-Proximal4.195318.45115HepG2SF3B4
chr14105723936105724045-intron-Distal4.307924.58989K562NONO
chr14105715928105715966-intron-Distal5.026877.32644K562SLTM
chr14105750478105750540-intron-Distal4.455193.97018HepG2HNRNPM
chr14105750218105750291-intron-Distal4.350894.66899HepG2HNRNPM
chr14105692667105692727-intron-Distal,intron-Proximal5.019436.40247K562SF3B4
chr14105689748105689831-intron-Distal5.002437.63393K562HNRNPM
chr14105738439105738499-intron-Distal4.127163.27946HepG2HNRNPM
chr14105682367105682438-intron-Distal3.923173.46495K562TARDBP
chr14105698729105698781-intron-Distal3.215193.74485K562DROSHA
chr14105715305105715374-intron-Distal,intron-Proximal6.0851112.64763HepG2SLTM
chr14105678195105678271-intron-Distal4.012643.53160K562RBFOX2
chr14105737231105737314-intron-Distal4.531485.01208K562MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BRF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BRF1 is not available on ENCORE database.

  • 82 RBPs can affect the levels of BRF1.  








The Knockdown/knockout RNA-Seq assay for BRF1 is not available on ENCORE database.





82 RBPs can affect the gene expression of BRF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BRF1ENSG00000185024.11104.43600177.81850-0.767802.815801.44350HepG2CSTF2T
BRF1ENSG00000185024.11333.64970240.398700.472802.740302.10040HepG2CELF1
BRF1ENSG00000185024.11495.39090346.363400.516205.182804.08830HepG2DDX19B
BRF1ENSG00000185024.11452.71720358.291900.337402.026001.43240HepG2DKC1
BRF1ENSG00000185024.11200.34250119.937800.740103.972603.14290HepG2DNAJC21
BRF1ENSG00000185024.11215.87230118.889700.860506.018905.11120HepG2DNAJC2
BRF1ENSG00000185024.11447.56460289.497500.628403.747603.06430HepG2EIF2S1
BRF1ENSG00000185024.11481.31180319.858200.589402.007601.46030HepG2EIF4A3
BRF1ENSG00000185024.11463.98990322.937000.522702.956702.24030HepG2FXR1
BRF1ENSG00000185024.11296.23310158.172300.905105.155403.23560HepG2HNRNPA0
BRF1ENSG00000185024.11191.61150121.087000.662002.473501.86010HepG2HNRNPA1
BRF1ENSG00000185024.11164.72310237.56940-0.528302.644201.72940HepG2HNRNPA2B1
BRF1ENSG00000185024.11246.87030154.434700.676703.098001.61690HepG2HNRNPAB
BRF1ENSG00000185024.11368.96960276.937400.413802.528901.84230HepG2HNRNPF
BRF1ENSG00000185024.11323.60330235.495500.458402.722502.05420HepG2HNRNPL
BRF1ENSG00000185024.11255.86510133.799800.935207.298006.35000HepG2HNRNPU
BRF1ENSG00000185024.11430.20680304.353700.499202.604701.94790HepG2IGF2BP2
BRF1ENSG00000185024.11194.45400136.671400.508602.300001.62430HepG2ILF2
BRF1ENSG00000185024.11355.24190178.208800.995103.356802.01750HepG2KHDRBS1
BRF1ENSG00000185024.11614.21990430.706600.511902.768101.93720HepG2LARP4
BRF1ENSG00000185024.11585.26760323.050700.857207.378306.32130HepG2MAGOH
BRF1ENSG00000185024.11529.90100332.447200.672503.500802.79240HepG2NCBP2
BRF1ENSG00000185024.11275.09180170.799900.687502.670901.80220HepG2PABPC1
BRF1ENSG00000185024.11189.02040132.434300.513202.177501.41810HepG2PARN
BRF1ENSG00000185024.11485.76040307.154400.661204.295503.56860HepG2PCBP1
BRF1ENSG00000185024.11309.22810119.338101.3735015.2635013.60290HepG2PPIL4
BRF1ENSG00000185024.11406.19810312.558700.378002.248801.74580HepG2PTBP1
BRF1ENSG00000185024.11343.65630244.692700.489902.523101.95070HepG2PUF60
BRF1ENSG00000185024.11444.03180259.743200.773508.860507.92720HepG2PUM1
BRF1ENSG00000185024.11430.34580338.471200.346401.918401.38360HepG2QKI
BRF1ENSG00000185024.11668.70430493.054600.439503.602003.03230HepG2RBM22
BRF1ENSG00000185024.11371.48480204.523300.860904.626803.32330HepG2RBM27
BRF1ENSG00000185024.11316.42060180.483900.809903.551401.82210HepG2RBM47
BRF1ENSG00000185024.11264.26560166.083600.670002.305501.33990HepG2RCC2
BRF1ENSG00000185024.11503.38290347.833200.533204.409203.75460HepG2NELFE
BRF1ENSG00000185024.11290.09220187.230900.631602.330601.76130HepG2RPS19
BRF1ENSG00000185024.11335.96920188.595300.832904.387903.39230HepG2RPS2
BRF1ENSG00000185024.11369.46880187.781300.976306.390905.17990HepG2RPS3A
BRF1ENSG00000185024.11304.64020119.152501.354208.851907.79930HepG2SAFB2
BRF1ENSG00000185024.11288.14510176.823000.704403.566802.08980HepG2SART3
BRF1ENSG00000185024.11743.74600440.954900.754105.733904.74120HepG2SF3A3
BRF1ENSG00000185024.11449.18850325.382400.465103.380602.73530HepG2SF3B4
BRF1ENSG00000185024.11387.20640234.603900.722806.657405.64430HepG2SLBP
BRF1ENSG00000185024.11246.78580138.948300.828605.865904.98380HepG2SMN1
BRF1ENSG00000185024.11303.26490179.688400.755003.425302.34660HepG2SMNDC1
BRF1ENSG00000185024.11426.88720241.587700.821208.424107.40700HepG2SRSF5
BRF1ENSG00000185024.11376.56900163.421001.2042010.211507.96110HepG2STIP1
BRF1ENSG00000185024.11407.99380274.760900.570304.657803.88840HepG2SUCLG1
BRF1ENSG00000185024.11214.51630305.31890-0.509202.705502.15080HepG2TAF15
BRF1ENSG00000185024.11313.91100129.997801.2718012.3275011.40320HepG2TIAL1
BRF1ENSG00000185024.11198.23310131.174600.595602.969002.38940HepG2TRIM56
BRF1ENSG00000185024.11452.96130239.039900.922004.831203.64390HepG2TUFM
BRF1ENSG00000185024.11485.71410253.010400.940806.706705.37400HepG2UBE2L3
BRF1ENSG00000185024.11206.33540101.765101.019602.127601.46200HepG2UCHL5
BRF1ENSG00000185024.11306.63640168.207900.866202.647401.58060HepG2XPO5
BRF1ENSG00000185024.11343.17730169.636801.016404.178803.29510HepG2XRN2
BRF1ENSG00000185024.11742.98360520.587700.513102.189301.67440K562AGGF1
BRF1ENSG00000185024.11736.20710572.098000.363702.718201.74760K562AKAP8
BRF1ENSG00000185024.11762.10340541.707600.492402.579801.94790K562AKAP8L
BRF1ENSG00000185024.11378.01310540.23250-0.515102.702402.11970K562AQR
BRF1ENSG00000185024.11706.77730568.405300.314202.438201.58530K562ATP5C1
BRF1ENSG00000185024.11355.65800217.177700.711503.653602.54370K562BCLAF1
BRF1ENSG00000185024.11264.08690164.761800.680502.873801.79760K562CSTF2
BRF1ENSG00000185024.11707.24180536.377000.398902.862302.19990K562DDX47
BRF1ENSG00000185024.11723.96120582.837800.312702.646101.79370K562DKC1
BRF1ENSG00000185024.11276.49010186.175700.570502.548801.67610K562EFTUD2
BRF1ENSG00000185024.11305.31170199.255100.615602.642601.63330K562EIF3D
BRF1ENSG00000185024.11206.95570133.611800.631203.016502.18570K562EIF3G
BRF1ENSG00000185024.11149.27190253.87600-0.766203.496102.20870K562FKBP4
BRF1ENSG00000185024.1147.56290127.30190-1.420304.240803.32360K562G3BP2
BRF1ENSG00000185024.11201.25290291.97610-0.536802.510701.93920K562HNRNPC
BRF1ENSG00000185024.11386.21830214.013600.851604.101102.74540K562IGF2BP2
BRF1ENSG00000185024.11719.49760574.843400.323702.343301.59300K562KIF1C
BRF1ENSG00000185024.11382.24470224.845300.765506.252904.96870K562MAGOH
BRF1ENSG00000185024.11803.84730643.975900.319802.585801.71230K562MBNL1
BRF1ENSG00000185024.11308.55520183.645700.748504.023202.39340K562NONO
BRF1ENSG00000185024.11296.99200200.043100.570003.034902.01050K562PCBP2
BRF1ENSG00000185024.11365.10800261.817900.479702.405601.56840K562PSIP1
BRF1ENSG00000185024.11289.98490218.456900.408502.008501.42600K562PTBP1
BRF1ENSG00000185024.11634.48350835.56990-0.397203.694602.44840K562PUM1
BRF1ENSG00000185024.11744.22530523.432100.507602.930802.32330K562RBM15
BRF1ENSG00000185024.11327.85880209.433400.646504.141503.08940K562RBM22
BRF1ENSG00000185024.11309.69920184.484600.747303.605502.67140K562RPS19
BRF1ENSG00000185024.1165.63140122.68810-0.902503.246701.50380K562SND1
BRF1ENSG00000185024.11284.70860180.992200.653503.260101.46140K562SRP68
BRF1ENSG00000185024.11315.67400214.169000.559603.100002.35490K562SRSF1
BRF1ENSG00000185024.11311.69520202.287200.623603.740802.48550K562SRSF5
BRF1ENSG00000185024.11282.09760175.307000.686203.194902.10070K562SUPV3L1
BRF1ENSG00000185024.11310.79350216.734900.519902.661501.96580K562TARDBP
BRF1ENSG00000185024.11349.05170209.070100.739405.370704.17360K562TIA1
BRF1ENSG00000185024.11335.54450189.071600.827505.245903.38190K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BRF1 is not available on ENCORE database.





5 RBPs can affect the splicing of BRF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSBRF1ENSG00000185024.11chr14-1056774581056776481056774581056776301056784491056785010.104000.016420.08076longerK562AQR
RIBRF1ENSG00000185024.11chr14-1056774581056785011056774581056776301056784491056785010.157000.000010.00167includedK562NPM1
RIBRF1ENSG00000185024.11chr14-1056774581056785011056774581056776301056784491056785010.167000.000590.00889includedK562AGGF1
RIBRF1ENSG00000185024.11chr14-1056774581056785011056774581056776301056784491056785010.173000.006000.05185includedHepG2RBM22
RIBRF1ENSG00000185024.11chr14-1056774581056785011056774581056776301056784491056785010.198000.001590.01027includedK562AQR
RIBRF1ENSG00000185024.11chr14-105677458105678501105677458105677630105678449105678501-0.266000.001830.03470excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BRF1 is not avaliable on ENCORE database.